CASE PRESENTATION: We report the case of a 44 year old man who presented with an ANCA-associated systemic vasculitis and aortic regurgitation of unusual mechanism. [ncbi.nlm.nih.gov]

• Palpable Spleen

  Examination confirmed aortic regurgitation, palpable spleen and left facial droop. Multiple peripheral blood cultures were negative. [ncbi.nlm.nih.gov]

• Upper Abdominal Pain

  RESULTS: We report a 66-year-old male with a history of renal cell carcinoma and bladder cancer who presented with upper abdominal pain, thoracic myelopathy (progressive weakness and numbness of the lower extremities, and gait disturbances), and weight [ncbi.nlm.nih.gov]

• Rectal Bleeding

  Two weeks before admission to a secondary level hospital, she developed fever up to 40 C followed by abdominal pain, rectal bleeding, hematemesis and blisters on both legs, reason for which she was hospitalized. [ncbi.nlm.nih.gov]

• Larva Migrans

  To our knowledge, this is the first observation of temporal vasculitis associated with helminthic infection, extending the clinical spectrum of visceral larva migrans. [ncbi.nlm.nih.gov]

Prompt referral for a complete rheumatologic workup in cases of unexplained hearing loss would allow for a timely diagnosis of a collagen vascular disease and facilitate early initiation of systemic therapy, possibly yielding better audiological results [ncbi.nlm.nih.gov]

Diagnostic workup for MPA reveals the presence of serum ANCA and absence of surface hepatitis B antigen or antibody. [slideshare.net]

Electrocardiograms (ECGs) are a series of leads placed on a person's chest that measure electrical activity associated with contraction of heart muscle.[83] The taking of an ECG is an important part in the workup of an AMI,[24] and ECGs are often not [en.wikipedia.org]

• Small Kidney

  Systemic vasculitis can be seen in around 10% of cases and may involve the large vessels, appearing as Takayasu-like vasculitis with affection of the aortic valve but also the coronary arteries and the small kidney vasculature. [ncbi.nlm.nih.gov]

• Pseudomonas

  Nosocomial or secondary infections occurred frequently: 8 ventilator associated pneumonia (Escherichia coli 1, Enterobacter aerogenes 1, Enterobacter cloacae 1, Xanthomonas maltophilia 1, Pseudomonas aeruginosa 1, Staphylococcus aureus 1, Mycobacterium [bmcanesthesiol.biomedcentral.com]

  Four (15%) patients died in the ICU, three of septic shock caused by Pseudomonas aeruginosa ( n  1), S. aureus ( n  1) pneumonia or urinary tract infection ( E. coli, n  1). [doi.org]

• Legionella Pneumophila

  Three (12%) patients were admitted to the ICU for infections, including pneumonia ( Legionella pneumophila, n  1; Staphylococcus aureus, n  1) and sepsis ( Escherichia coli, n  1), after 1 month of immunosuppressive treatment for newly diagnosed HBV-related [doi.org]

• Bartonella Henselae

  Grindings from aortic valve leaflets were analysed for rpoB gene, which confirmed the presence of Bartonella henselae. Serological assays demonstrated B henselae IgM 20 (normal 2048 (normal 64). [ncbi.nlm.nih.gov]

• Arterial Biopsy showing Vasculitis

  showing vasculitis with mononuclear cell infiltrate or granulomatous inflammation, usually with multinucleated giant cells These conditions are sometimes considered together with the small vessel vasculitides.Polyarteritis nodosa (PAN). [en.wikipedia.org]

Long-term treatment and disease-related morbidity are major threats. The last decade has seen a collaborative international effort to determine effective treatment. [ncbi.nlm.nih.gov]

The combination of vasculitis and cardiomyopathy is associated with a poor prognosis. Early treatment with immunosuppressants in conjunction with appropriate cardiac pharmacotherapy is considered important and has dramatically improved prognosis. [ncbi.nlm.nih.gov]

For example, a patient with purpura, nephritis, and abdominal pain caused by Henoch–Schönlein purpura usually has a good prognosis. .. [doi.org]

All patients with a vasculitis of unidentified etiology should be evaluated for HIV infection. [ncbi.nlm.nih.gov]

Homepage Rare diseases Search Search for a rare disease Vasculitis Disease definition Vasculitis represents a clinically heterogenous group of diseases of multifactorial etiology characterized by inflammation of either large-sized vessels (large-vessel [orpha.net]

These protean clinical manifestations, combined with the etiologic nonspecificity of the histologic lesions, complicate the diagnosis of specific forms of vasculitis. [doi.org]

[…] provide our annual digest of the recent literature on systemic vasculitis in which we reviewed all the articles published during the last 12 months on large-, medium- and small-vessel vasculitis, and selected the most relevant studies regarding the epidemiology [ncbi.nlm.nih.gov]

: Epidemiology of vasculitis in Europe. Ann Rheum Dis 2001, 60 :1156–1157. PubMed CrossRef Google Scholar 6. [link.springer.com]

Subsequently, we review the literature on the combination of myelodysplastic syndromes and systemic vasculitis and discuss the prognostic consequences, considerations for treatment and possible pathophysiological mechanisms. [ncbi.nlm.nih.gov]

Access personal reporting Related Content This Book Etiology, Pathogenesis and Pathophysiology of Aortic Aneurysms and Aneurysm Rupture Edited by Reinhart Grundmann Next chapter Drug-induced aortic aneurysms, ruptures and dissections By Olav Spigset Related [intechopen.com]

BOSTON— The latest research on the pathophysiology and treatment of small- and large-vessel vasculitides was presented by three international experts at a clinical symposium called “Therapeutic Decisions in Systemic Vasculitis” at the ACR/ARHP Annual [the-rheumatologist.org]

In some vasculitic disorders, such as granulomatosis with polyangiitis or Kawasaki disease, the vessel inflammation (true vasculitis) is only part of the pathophysiology and there is predominant parenchymal inflammation in a characteristic pattern that [merckmanuals.com]

Transthoracic and transesophageal echocardiography disclosed septal hypertrophy preventing a complete closure of the aortic valve and thus responsible for a massive aortic regurgitation. [ncbi.nlm.nih.gov]