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Temporal Lobe Tumor

Neoplasm of Temporal Lobe of Brain


Presentation

  • Background: Brain tumors, even large ones, may present with minimal ENT symptoms including minimal hearing loss.[thieme-connect.com]
  • Thus, PXA could present with a divergent differentiation, as seen in the present case [ 19 ].[diagnosticpathology.biomedcentral.com]
  • Eight patients (38.1%) presented GTCS, six (37.5%) in group I and one (20%) in the non seizure free group. Five patients had presented status epilepticus. Also in these data no significant association was found ( Table 2 ).[scielo.br]
  • The original patient images from the patient’s first surgery were not present. The Diffusion Weighted Images (DWI) from his most recent MRI of the brain showed the following (Below).[cns.org]
  • Wolpow, EEG Laboratory, Massachusetts General Hospital, Boston, MA 02114 (USA) Abstract PDF Abstract Six pathologically verified cases are presented in which temporal lobe tumor (glioma or metastatic carcinoma) was associated in the EEG with regular ¾[karger.com]
Anosmia
  • Location - Olfactory Groove and sella (bony space where the pituitary gland is situated) Common Symptoms - Loss of smell (anosmia), subtle personality changes, mild difficulty with memory, euphoria, diminished concentration, urinary incontinence, visual[neurosurgery.ucla.edu]
Constitutional Symptom
  • He denies any recent fevers, chills, weight loss or other constitutional symptoms. PMH: 1. Orchiectomy 10 years ago for an undescended right testicle 2. Diabetes SOCIAL HISTORY: The patient works as a computer animator.[cns.org]
Aggressive Behavior
  • After craniotomy for tumor removal, both patients were seizure-free and had marked reductions in their aggressive behavior.[pediatrics.aappublications.org]
  • behavior towards themselves and/or others.[en.wikipedia.org]
  • […] lobe tumors may cause: vision loss in one or both eyes, visual field cuts; blurred vision, illusions, hallucinations Temporal lobe tumors may cause: difficulty speaking and understanding language; short-term and long-term memory problems; increased aggressive[mayfieldclinic.com]
Anger
  • Moody feelings and risky behavior iStock/SIphotography “Patients suffering from a brain tumor may develop depression, anger or anxiety, even if they don’t commonly exhibit these types of emotions,” says Sumeet Vadera, MD, neurosurgeon at the University[rd.com]
  • A lot happened from surgery to present . but yes bursts of anger does occur ...and hypothyroid....I think there is something else missing (diagnose) as a continous red flush is constantly on checks I should note that my son excels in school honors and[inspire.com]
Visual Hallucination
  • "Assuming for now a more rational scientific view, he was having a visual hallucination and he heard God's voice," Devinsky observes. It could have been God; it could have been a seizure.[npr.org]
  • Case 5 The salient features in the video of this 6-year-old, left-handed girl who started having seizures at the age of two years include the initial cry, which probably represents an aura of fear probably in response to a visual hallucination (she reported[jle.com]
Auditory Hallucination
  • Its most explicit symptom is the perception of external voices in the form of auditory hallucinations.[en.wikipedia.org]
Emotional Outbursts
  • The emotional outbursts range from intense ecstasy to profound despair. In some cases there may be a sense impending doom or even fits of extreme rage and terror. Women patients sometimes experience orgasm during temporal lobe seizure.[netmind2011.blogspot.com]
Seizure
  • Of the study group of 35 patients, 27 (77.1%) became completely seizure free after surgery (class I), and 2 patients (5.7%) had no more than 2 seizures per year (class II). Worthwhile seizure control was achieved in 29 patients (82.8%).[ncbi.nlm.nih.gov]
  • Although the duration of seizure has been reported to be adversely related to the seizure outcome by some authors, [6] , [13] we have not observed any definite association between the seizure control and duration, type or frequency of seizure and age[pediatricneurosciences.com]
  • In the seizure free group the seizure frequency ranged from 2 to 45 per month (mean: 10.25) and in the non seizure free group ranged from 6 to 180 (mean: 52.8).[scielo.br]
  • Seizure . 1999 ; 8 : 480 – 484 Caplan R, Comair Y, Shewmon DA, Jackson L, Chugani HT, Peacock WJ. Intractable seizures, compulsions, and coprolalia: a pediatric case study.[pediatrics.aappublications.org]
  • A seizure duration of almost 60 years was not reported earlier. Most probably, the lesion was already present at the beginning of his seizures, 57 years ago.[surgicalneurologyint.com]
Confusion
  • A person with Wernicke’s dysphasia may also suffer from a lack in comprehension, confusing them further. A person with a temporal lobe tumor may also suffer from slurred speech though they comprehend information normally.[livestrong.com]
  • Confusion, short term memory loss, vision loss, less side numbness, cognitive deficits. Any experiences would be great. I had a tumor removed that was benign (not cancerous), but growing against the base of my right temporal lobe.[cancercompass.com]
  • Altered perception of touch or pressure, arm or leg weakness on 1 side of the body, or confusion with left and right sides of the body are linked to a tumor in the frontal or parietal lobe of the cerebrum.[cancer.net]
Personality Change
  • Location - Sphenoid Ridge Common Symptoms - Eye-bulging, decreased vision, paralysis of eye movement, seizures, memory difficulty, personality change, headache.[neurosurgery.ucla.edu]
  • Symptoms may include headaches, personality changes (such as suddenly becoming depressed, anxious, or uninhibited), loss of balance, trouble concentrating, seizures, and incoordination.[merckmanuals.com]
  • Symptoms in older people In elderly people, vague symptoms could be put down to getting older such as: memory loss personality changes difficulty walking If several symptoms like these develop over less than 6 months, it is worth checking in with your[cancerresearchuk.org]
  • The most common symptoms are seizures, headaches, and personality changes. Other symptoms vary by location and size of the tumor.[abta.org]
Amnesia
  • The difference between retrograde and anterograde amnesia is that retrograde amnesia is loss of memory from before an event.[patient.info]
  • […] long term memory . [4] : 194–199 The medial temporal lobes include the hippocampi , which are essential for memory storage, therefore damage to this area can result in impairment in new memory formation leading to permanent or temporary anterograde amnesia[en.wikipedia.org]
  • The symptoms that i do currently have are memory problems equivalent to GTA (global temporary amnesia) which has been an ongoing issue for about a year and a half, severe ongoing headaches, tiredness, extreme difficulty with problem solving/making decisions[inspire.com]
  • (the functions are the opposite in men and women, right left) I have been completely frustrated with my outcome...yea, nice to be alive...but feel far from being Normal...due to emotionalism, short term memory, amnesia, a Naiveness that embarrasing, etc[braintumour.ca]
Deja Vu
  • I started having reoccuring instances when I would feel an intense deja vu and experience hallucinations, hear voices, but wouldn't remember anything afterwards.[epilepsy.com]
  • Metallic taste, always on the left side of my mouth, deja vu, and sometimes a little disorientation. The visuals, yes, thats part of it. But within a minute, you're back. As I said, time will pass and you'll learn to deal with it.[community.macmillan.org.uk]
  • vu extreme happiness a rising sensation in the abdomen anxiety These early signs are called auras or warnings, and they may last for a few seconds up to a few minutes before the seizure occurs.[healthline.com]

Workup

  • METHODS: In patients who presented with intractable seizures secondary to mass lesions and underwent comprehensive epilepsy workup, the tumor was resected and the diagnosis confirmed by pathological examination.[ncbi.nlm.nih.gov]
  • Here’s when to consider seeing your doctor for a workup.[rd.com]
  • All patients underwent comprehensive pre- and postsurgical workups, including a thorough seizure history, neurological examinations, neuroimaging studies (magnetic resonance imaging with seizure protocol) and routine electroencephalogram (EEG) recordings[pediatricneurosciences.com]

Treatment

  • […] clinics have in their treatment solutions.[inspire.com]
  • Asked for Female, 63 Years 121 Views v Any symptomatic brain tumor (Tumor that causes some or the other symptoms) requires treatment. One of the aspects of the treatment is to find out the type of tumor, whether it is a tumor or something ...[practo.com]
  • Hippocampectomy as the treatment of tumor-associated epilepsy in the absence of hippocampal atrophy is debatable.[pediatricneurosciences.com]
  • OBJECT: Surgical treatment of brain tumors in the mesial temporal lobe (MTL) is a highly demanding procedure.[ncbi.nlm.nih.gov]

Prognosis

  • Lesionectomy associated with partial mesial resection did not guarantee a better prognosis.[scielo.br]
  • Otherwise underdiagnosis may result in substantial delay affecting management and prognosis.[thieme-connect.com]
  • The MTL tumors are heterogeneous in their prognosis. Older age, short duration of epilepsy, and tumor size are all associated with poor outcome.[ncbi.nlm.nih.gov]
  • This strategy may produce acceptable control of seizures; however, it must be considered against the excellent prognosis provided by surgery.[pediatrics.aappublications.org]

Etiology

  • Infectious and vascular etiologies would also be on the differential for this patient. Infectious etiologies to consider are an abscess and limbic encephalitis. Abscesses can have a range of characteristics on MRI depending on the age of the lesion.[frontiersin.org]
  • Etiology as a risk factor for medically refractory epilepsy: a case for early surgical intervention.[scielo.br]
  • Paramasivam, Gowrishankar; Ghi, Tullio; Galli, Letizia; Groenenberg, Irene AL; Tangi, Amanda; Accorsi, Patrizia; Echevarria, Monica; Angeles Rodríguez Perez, Maria; Albaiges Baiget, Gerard; Prefumo, Federico; Frusca, Tiziana; Go, Attie TJI; Lees, Christoph C: Etiology[thieme-connect.com]
  • Characteristic Infants and toddlers (0-3 years) Pre-school and early school (3-6 years) Older children, adolescents and adults ( 6 years) Etiology Cortical dysplasia, Low grade neoplasms, Tuberous sclerosis, etc; hippocampal sclerosis uncommon Cortical[jle.com]
  • […] autoimmune) Gliomatosis cerebri Peri- or postictal edema Infarction Additional Key Images and Findings in (Figure 2) Discussion The differential diagnosis in a patient with cortically-based temporal lobe signal abnormality on MRI is broad and includes etiologies[jaocr.org]

Epidemiology

  • The observations of the present case did not completely correspond with any differential diagnosis with regard to epidemiological, radiological, and histological findings.[diagnosticpathology.biomedcentral.com]
  • References 1 Epidemiology and molecular pathology of glioma , Nat Clin Pract Neurol , 2006 , vol. 2(9) (pg. 494 - 503 ) 2 Cognitive impairments in patients with low grade gliomas and high grade gliomas , Arq Neuro-Psiquiatr , 2011 , vol. 69 4 (pg. 596[academic.oup.com]
  • Epidemiology [ edit ] Epilepsy is a relatively common disorder, affecting between 0.5-1% of the population, [36] and frontal lobe epilepsy accounts for about 1-2% of all epilepsies. [3] The most common subdivision of epilepsy is symptomatic partial epilepsy[en.wikipedia.org]
  • Classification, epidemiology, and etiology of brain tumors. Samuels MA, Feske S, eds. Office Practice of Neurology . 2nd ed. Philadelphia, Pa: Churchill Livingstone; 2003. 1006-13. Van der Drift JHA, Magnus O. EEG and cerebral tumor.[emedicine.medscape.com]
Sex distribution
Age distribution

Pathophysiology

  • It is thus obvious that a proper understanding of the pathophysiological mechanisms leading to tumoral epilepsy is essential, and without this, it may be difficult to determine the optimal surgical strategy.[pediatricneurosciences.com]

Prevention

  • Purpose Lobectomies are usually performed to prevent the spread of cancer from part of one organ to other parts of the organ or other parts of the body.[encyclopedia.com]
  • When symptoms occur, it's because the tumour is putting pressure on the brain and preventing a specific area of the brain from functioning properly.[nhs.uk]
  • 10] , [11] , [12] Tumor removal is not only associated with effective seizure control, it can also improve psychological and intellectual development of the patient, reduce the incidence of secondary epileptogenesis, ensure an accurate diagnosis and prevent[pediatricneurosciences.com]
  • Can temporal lobe lesions be prevented? There is a great deal we can do to reduce our risk of a stroke. See separate leaflet called Preventing Cardiovascular Diseases for more details .[patient.info]

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