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Temporal Lobe Tumor

Neoplasm of Temporal Lobe of Brain


Presentation

  • : Brain tumors, even large ones, may present with minimal ENT symptoms including minimal hearing loss.[thieme-connect.com]
  • Eight patients (38.1%) presented GTCS, six (37.5%) in group I and one (20%) in the non seizure free group. Five patients had presented status epilepticus. Also in these data no significant association was found ( Table 2 ).[scielo.br]
  • Thus, PXA could present with a divergent differentiation, as seen in the present case [ 19 ].[diagnosticpathology.biomedcentral.com]
  • The original patient images from the patient’s first surgery were not present. The Diffusion Weighted Images (DWI) from his most recent MRI of the brain showed the following (Below).[cns.org]
  • We describe 2 cases involving pediatric patients who presented with histories of unusually aggressive and antisocial behavior. Magnetic resonance imaging identified right mesial temporal lobe masses in both patients.[pediatrics.aappublications.org]
Wound Infection
  • The postoperative complications were observed in 4 patients (25%), including temporary hemiparesis in 2 cases, superior quadrant field defect in 3, transient psychosis in 1 and wound infection in 1.[pediatricneurosciences.com]
Anosmia
  • Location - Olfactory Groove and sella (bony space where the pituitary gland is situated) Common Symptoms - Loss of smell (anosmia), subtle personality changes, mild difficulty with memory, euphoria, diminished concentration, urinary incontinence, visual[neurosurgery.ucla.edu]
Hemianopsia
  • “This particular symptom of impaired peripheral vision is known as bitemporal hemianopsia,” says Christopher Carrubba, MD, co-director for medical education at Med School Tutors.[rd.com]
Aggressive Behavior
  • After craniotomy for tumor removal, both patients were seizure-free and had marked reductions in their aggressive behavior.[pediatrics.aappublications.org]
  • behavior towards themselves and/or others.[en.wikipedia.org]
  • […] lobe tumors may cause: vision loss in one or both eyes, visual field cuts; blurred vision, illusions, hallucinations Temporal lobe tumors may cause: difficulty speaking and understanding language; short-term and long-term memory problems; increased aggressive[mayfieldclinic.com]
Auditory Hallucination
  • Its most explicit symptom is the perception of external voices in the form of auditory hallucinations.[en.wikipedia.org]
Anger
  • Moody feelings and risky behavior iStock/SIphotography “Patients suffering from a brain tumor may develop depression, anger or anxiety, even if they don’t commonly exhibit these types of emotions,” says Sumeet Vadera, MD, neurosurgeon at the University[rd.com]
  • A lot happened from surgery to present. but yes bursts of anger does occur ...and hypothyroid....I think there is something else missing (diagnose) as a continous red flush is constantly on checks I should note that my son excels in school honors and[inspire.com]
Visual Hallucination
  • "Assuming for now a more rational scientific view, he was having a visual hallucination and he heard God's voice," Devinsky observes. It could have been God; it could have been a seizure.[npr.org]
Emotional Outbursts
  • The emotional outbursts range from intense ecstasy to profound despair. In some cases there may be a sense impending doom or even fits of extreme rage and terror. Women patients sometimes experience orgasm during temporal lobe seizure.[netmind2011.blogspot.com]
Seizure
  • Of the study group of 35 patients, 27 (77.1%) became completely seizure free after surgery (class I), and 2 patients (5.7%) had no more than 2 seizures per year (class II). Worthwhile seizure control was achieved in 29 patients (82.8%).[ncbi.nlm.nih.gov]
  • seizure-free after a subtotal resection.[pediatricneurosciences.com]
  • In the seizure free group the seizure frequency ranged from 2 to 45 per month (mean: 10.25) and in the non seizure free group ranged from 6 to 180 (mean: 52.8).[scielo.br]
  • Seizure. 1999 ; 8 : 480 – 484 Caplan R, Comair Y, Shewmon DA, Jackson L, Chugani HT, Peacock WJ. Intractable seizures, compulsions, and coprolalia: a pediatric case study.[pediatrics.aappublications.org]
  • A seizure duration of almost 60 years was not reported earlier. Most probably, the lesion was already present at the beginning of his seizures, 57 years ago.[surgicalneurologyint.com]
Confusion
  • A person with Wernicke’s dysphasia may also suffer from a lack in comprehension, confusing them further. A person with a temporal lobe tumor may also suffer from slurred speech though they comprehend information normally.[livestrong.com]
  • Confusion, short term memory loss, vision loss, less side numbness, cognitive deficits. Any experiences would be great. I had a tumor removed that was benign (not cancerous), but growing against the base of my right temporal lobe.[cancercompass.com]
  • Altered perception of touch or pressure, arm or leg weakness on 1 side of the body, or confusion with left and right sides of the body are linked to a tumor in the frontal or parietal lobe of the cerebrum.[cancer.net]
Personality Change
  • Location - Sphenoid Ridge Common Symptoms - Eye-bulging, decreased vision, paralysis of eye movement, seizures, memory difficulty, personality change, headache.[neurosurgery.ucla.edu]
  • Symptoms in older people In elderly people, vague symptoms could be put down to getting older such as: memory loss personality changes difficulty walking If several symptoms like these develop over less than 6 months, it is worth checking in with your[cancerresearchuk.org]
  • The most common symptoms are seizures, headaches, and personality changes. Other symptoms vary by location and size of the tumor.[abta.org]
  • I am very happy to say he has had no personality changes, memory loss, or any other deficits from his surgery. He was in the hospital for two days after the surgery and then only took a week off from work.[inspire.com]
Irritability
  • ., irritability) Difficulty speaking and swallowing Drowsiness Headache, especially in the morning Hearing loss Muscle weakness on one side of the face (e.g., head tilt, crooked smile) Muscle weakness on one side of the body (i.e., hemiparesis) Uncoordinated[healthcommunities.com]
  • Fecal transplant is used to treat gut infections and is now being studied as a treatment for obesity, urinary tract infections, irritable bowel syndrome and more.[nytimes.com]
  • “This is related to tumor irritation or compression of portions of the frontal lobe, which is responsible for many of our personality traits.”[rd.com]
  • The proposed hypotheses include direct pressure and irritation in the cortical tissue, gliosis, disrupted vascularization in the surrounding cortex, morphological neuronal alterations in cellular levels, changes in the level of neurotransmitters, denervation[pediatricneurosciences.com]
  • Increased pressure on the brain If the tumour causes an increase in pressure inside the skull, it can lead to the following symptoms: epilepsy or fits, which can be either major seizures or twitching in one area of the body severe, persistent headache irritability[your.md]
Amnesia
  • The difference between retrograde and anterograde amnesia is that retrograde amnesia is loss of memory from before an event.[patient.info]
  • […] the recognition of faces and distinction of unique individual facial features. [9] Damage specifically to the anterior portion of the left temporal lobe can cause savant syndrome. [10] Disorders [ edit ] Pick's disease, also known as frontotemporal amnesia[en.wikipedia.org]
  • (the functions are the opposite in men and women, right left) I have been completely frustrated with my outcome...yea, nice to be alive...but feel far from being Normal...due to emotionalism, short term memory, amnesia, a Naiveness that embarrasing, etc[braintumour.ca]
  • The symptoms that i do currently have are memory problems equivalent to GTA (global temporary amnesia) which has been an ongoing issue for about a year and a half, severe ongoing headaches, tiredness, extreme difficulty with problem solving/making decisions[inspire.com]

Workup

  • METHODS: In patients who presented with intractable seizures secondary to mass lesions and underwent comprehensive epilepsy workup, the tumor was resected and the diagnosis confirmed by pathological examination.[ncbi.nlm.nih.gov]
  • Here’s when to consider seeing your doctor for a workup.[rd.com]
  • All patients underwent comprehensive pre- and postsurgical workups, including a thorough seizure history, neurological examinations, neuroimaging studies (magnetic resonance imaging with seizure protocol) and routine electroencephalogram (EEG) recordings[pediatricneurosciences.com]
Lymphocytic Infiltrate
  • The other part of the lesion [ Figure 4 ] had a clear neuronal and glial component and showed large and polymorph ganglion cells in a fibrillary matrix with glial cells and perivascular lymphocytic infiltrates.[surgicalneurologyint.com]

Treatment

  • […] clinics have in their treatment solutions.[inspire.com]
  • Asked for Female, 63 Years 148 Views v Any symptomatic brain tumor (Tumor that causes some or the other symptoms) requires treatment. One of the aspects of the treatment is to find out the type of tumor, whether it is a tumor or something ...[practo.com]
  • Hippocampectomy as the treatment of tumor-associated epilepsy in the absence of hippocampal atrophy is debatable.[pediatricneurosciences.com]
  • All patients were considered refractory to medical treatment and presented complex partial seizures (CPS).[scielo.br]
  • OBJECT: Surgical treatment of brain tumors in the mesial temporal lobe (MTL) is a highly demanding procedure.[ncbi.nlm.nih.gov]

Prognosis

  • Lesionectomy associated with partial mesial resection did not guarantee a better prognosis.[scielo.br]
  • Otherwise underdiagnosis may result in substantial delay affecting management and prognosis.[thieme-connect.com]
  • The MTL tumors are heterogeneous in their prognosis. Older age, short duration of epilepsy, and tumor size are all associated with poor outcome.[ncbi.nlm.nih.gov]
  • This strategy may produce acceptable control of seizures; however, it must be considered against the excellent prognosis provided by surgery.[pediatrics.aappublications.org]

Etiology

  • Infectious and vascular etiologies would also be on the differential for this patient. Infectious etiologies to consider are an abscess and limbic encephalitis. Abscesses can have a range of characteristics on MRI depending on the age of the lesion.[frontiersin.org]
  • Etiology as a risk factor for medically refractory epilepsy: a case for early surgical intervention.[scielo.br]
  • […] autoimmune) Gliomatosis cerebri Peri- or postictal edema Infarction Additional Key Images and Findings in (Figure 2) Discussion The differential diagnosis in a patient with cortically-based temporal lobe signal abnormality on MRI is broad and includes etiologies[jaocr.org]
  • Classification, epidemiology, and etiology of brain tumors. Samuels MA, Feske S, eds. Office Practice of Neurology. 2nd ed. Philadelphia, Pa: Churchill Livingstone; 2003. 1006-13. Van der Drift JHA, Magnus O. EEG and cerebral tumor.[emedicine.medscape.com]
  • Wilms' tumor a rapidly developing malignant mixed tumor of the kidneys, made up of embryonal elements, occurring chiefly in children before the seventh year; a genetic component is suspected in its etiology.[medical-dictionary.thefreedictionary.com]

Epidemiology

  • The observations of the present case did not completely correspond with any differential diagnosis with regard to epidemiological, radiological, and histological findings.[diagnosticpathology.biomedcentral.com]
  • Definition / general Well differentiated neuroepithelial tumors composed of neoplastic ganglion cells (gangliocytoma) or combination of neoplastic ganglion cells and neoplastic glial component (ganglioglioma) Epidemiology 2% of all brain tumors Ages 2[pathologyoutlines.com]
  • References 1 Epidemiology and molecular pathology of glioma, Nat Clin Pract Neurol, 2006, vol. 2(9) (pg. 494 - 503 ) 2 Cognitive impairments in patients with low grade gliomas and high grade gliomas, Arq Neuro-Psiquiatr, 2011, vol. 69 4 (pg. 596 - 601[academic.oup.com]
  • Epidemiology [ edit ] Epilepsy is a relatively common disorder, affecting between 0.5-1% of the population, [35] and frontal lobe epilepsy accounts for about 1-2% of all epilepsies. [3] The most common subdivision of epilepsy is symptomatic partial epilepsy[en.wikipedia.org]
  • Classification, epidemiology, and etiology of brain tumors. Samuels MA, Feske S, eds. Office Practice of Neurology. 2nd ed. Philadelphia, Pa: Churchill Livingstone; 2003. 1006-13. Van der Drift JHA, Magnus O. EEG and cerebral tumor.[emedicine.medscape.com]
Sex distribution
Age distribution

Pathophysiology

  • It is thus obvious that a proper understanding of the pathophysiological mechanisms leading to tumoral epilepsy is essential, and without this, it may be difficult to determine the optimal surgical strategy.[pediatricneurosciences.com]

Prevention

  • Purpose Lobectomies are usually performed to prevent the spread of cancer from part of one organ to other parts of the organ or other parts of the body.[encyclopedia.com]
  • When symptoms occur, it's because the tumour is putting pressure on the brain and preventing a specific area of the brain from functioning properly.[nhs.uk]
  • Can temporal lobe lesions be prevented? There is a great deal we can do to reduce our risk of a stroke. See separate leaflet called Preventing Cardiovascular Diseases for more details .[patient.info]
  • This happens because the tumour prevents that part of the brain from working normally. In the frontal lobe – changes in personality or behaviour, uncoordinated walking or weakness on one side of the body.[express.co.uk]

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