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Teratoma of the Brain

Teratoma of Brain


Presentation

  • Summary A report is presented here of the total extirpation of a teratoma located in the third ventricle of a boy of eight. Since the tumour was made up of mature tissues (adult teratoma), its extirpation may be regarded as a cure.[link.springer.com]
  • Clinical presentation varies according to whether they are intra- or extra-axial. Intra-axial Intra-axial teratomas typically present either antenatally or in the newborn period.[radiopaedia.org]
  • He is board certified in neurological surgery and pediatric neurological surgery, contributed to many publications, book chapters and presentations on pediatric neurosurgery, and has taught at several university medical schools. In addition, Dr.[beckershospitalreview.com]
  • The predilection of neonatal brain tumors for supratentorial locations was also observed in this series of tumors present at birth.[ncbi.nlm.nih.gov]
  • This toxicity presents risks for bleeding, anemia, and infection.[childhoodbraintumor.org]
Falling
  • Karanam, a Ph.D. student at the University of Indiana, first noticed that something was off when she struggled with reading and listening comprehension last fall, Newser reported.[medicaldaily.com]
  • Starting last fall, something seemed to have changed. Fatigue consumed the Indiana University-Purdue University Indiana student. She found herself sleeping 15 hours or more a day — and she was still exhausted.[usatoday.com]
  • "The fear of falling overcomes him when the trail narrows."[deseretnews.com]
Epilepsy
  • Each brain tumor and epilepsy case is unique and traditional treatment methods are well established and broadly efficacious.[beckershospitalreview.com]
  • After the then 24-year-old suffered her first seizure, a neurologist suggested she was simply partying too hard and prescribed her an epilepsy medication. A psychiatrist gave her an antipsychotic used to treat bipolar disorder.[bostonglobe.com]
Surgical Procedure
  • In the EXIT procedure, the fetus is partially delivered by cesarean section and undergoes intubation or surgical procedures while the placenta and umbilical cord remain intact.[e-ultrasonography.org]
Cesarean Section
  • The male baby was delivered by cesarean section at 36 GW and he had facial dimorphism with right exophthalmos. The tumor volume continued to increase after surgery and the baby died at 123 days of life.[degruyter.com]
  • Cesarean section should be performed before the labor stars 2. The incidence of cesarean section is still 60.4%, because cephalopelvic disproportion is common 3.[ispub.com]
  • Method: cesarean section if the fetal head circumference is 40 cm. Prognosis: Survival rate: Recurrence: No increased risk of recurrence.[fetalmedicine.org]
  • section because of abnormally large head size and difficult delivery.[ijpmonline.org]
  • Hopefully this finding will suggest something that can be done to prevent obstetricians from having to tell patients having Cesarean sections that they’ve given birth to baseballs. But at least my baseballs didn’t have hair and teeth in them.[blogs.plos.org]
Headache
  • Janell's medical mystery began with severe "blinding" headaches. These headaches were soon followed by seizures. Most people associate seizures with the generalized convulsions -- when the patient physically collapses and loses consciousness.[abc.go.com]
  • A common initial symptom of a brain tumor is headaches. Often, they don't respond to the usual headache remedies. Keep in mind that most headaches are unrelated to brain tumors.[webmd.com]
  • She asked me later after school how was my headache and I remember thinking to myself, "headache, what headache? I do not remember such thing at all???"[csn.cancer.org]
  • "Then came the headaches. Slips and misses at work," she wrote on her blog. "There were doctors. First, a couple of them and then more."[cbsnews.com]
  • Well Think Like a Doctor: An Unusual Headache Solved See next articles See previous articles By Lisa Sanders, M.D.[well.blogs.nytimes.com]
Seizure
  • For example, nearly eight months after using Visualase, one 14-year-old Children's patient, who previously needed frequent open surgeries when her medications failed to ease her chronic epileptic seizures, is now seizure-free.[beckershospitalreview.com]
  • These headaches were soon followed by seizures. Most people associate seizures with the generalized convulsions -- when the patient physically collapses and loses consciousness.[abc.go.com]
  • Motor and complex seizures may develop, including status epilepticus (continuous seizures), coma can occur and mechanical ventilation is required to maintain breathing.[hormonesmatter.com]
  • Neuropsychologic changes observed with this disease include agitation, mood lability, speech dysfunction, hallucinations, paranoia, hypersexuality, and seizures.[mdedge.com]
  • Then she, too, had a seizure. The women’s slow unraveling could have been the beginning of a psychotic break, followed by a lifetime of hospitalization and medication.[bostonglobe.com]
Stroke
  • Updated coverage of brain trauma addresses newly recognized entities, techniques and imaging for rapid stroke triage, and functional imaging and dementia diagnosis.[books.google.com]
  • They suspect that it maybe an infarction - silent stroke rather than a new cancer. But at this time not sure. Long story short... Could you tell me about the growth hormones. Our doctors don't want to add "growth hormones" at this time.[csn.cancer.org]
Papilledema
  • On physical examination, except for mild papilledema, no positive neurological signs were found.[medsci.org]
Encephalopathy
  • The doctors were worried she could have some infectious encephalopathy and that was the only single room available. The patient didn’t know what the doctors were thinking.[well.blogs.nytimes.com]

Workup

  • For teratomas, which cannot be distinguished clinically from other tumours, the patient workup should be the same as would be for the evaluation of any other suspicious testicular masses.[omicsonline.org]

Treatment

  • The survivor is disease-free 12 months after completing treatment, which included extensive use of chemotherapy, surgery and radiotherapy.[nature.com]
  • Each brain tumor and epilepsy case is unique and traditional treatment methods are well established and broadly efficacious.[beckershospitalreview.com]
  • ., Treatment of tumours of the posterior part of the third ventricle and the pineal region: A long term follow-up. Acta Neurochir. (Wien) 40 (1978), 131–143. Google Scholar 2. Cole, H., Tumours in the region of the pineal. Clin.[link.springer.com]
  • Treatment for children may be different than treatment for adults.[cancer.gov]
  • Being well informed about your tumour and its treatment can make it easier to make decisions and cope with what happens. Follow up You will have regular check ups once you finish your treatment.[cancerresearchuk.org]

Prognosis

  • Prognosis As with many types of cancer the prognosis for those with teratoma varies greatly depending on the type of teratoma, the size and the location of the tumor. Where complete removal of the teratoma is possible prognosis is very good.[knowcancer.com]
  • Only 5 % of childhood brain tumors arise in fetal and their prognosis is poor 2. Teratomas are the most common congenital tumors 1,3,4,5,6.[ispub.com]
  • Location and size determine prognosis: intra-axial (fetal) lesions: stillbirth occurs relatively frequently, and difficulty with vaginal delivery (if attempted) can occur due to enlarged cranial circumference 3 extra-axial lesions: largely depends on[radiopaedia.org]
  • , or therapies New developments in treatment As with any cancer, prognosis and long-term survival can vary greatly from individual to individual.[stanfordchildrens.org]
  • The embryonal subtype is most common in children and has the best prognosis, but all have a poor prognosis if they occur in perinatal period and are in an advanced stage [ 59, 60 ].[e-ultrasonography.org]

Etiology

  • Etiology With sacrococcygeal teratomas, no causative agents are known. With respect to ovarian germ cell tumors, a familial predilection may be present.[emedicine.medscape.com]

Epidemiology

  • They can be divided into two broad categories, intra- and extra-axial , which differ in epidemiology and clinical presentation. Another method of classifying an intracranial teratoma is as mature, immature and mature with malignant transformation.[radiopaedia.org]
  • The risk factors and epidemiologic features of testicular cancer suggest that cryptorchidism increases the risk of germ cell tumor by a factor of 10. Tumors may appear in the ipsilateral or contralateral testicle.[emedicine.medscape.com]
  • Grady RW, Ross JH, Kay R (1997) Epidemiological features of testicular teratoma in a prepubertal population. J Urol 158: 1191-1192. Carver BS, Al-Ahmadie H, Sheinfeld J (2007) Adult and pediatric testicular teratoma. Urol Clin North Am 34: 245-251.[omicsonline.org]
  • Adequate follow-up requires close observation, involving repeated physical examination, scanning (ultrasound, MRI, or CT), and measurement of AFP and/or βhCG. [50] [51] Epidemiology [ edit ] Embryonal teratomas most commonly occur in the sacrococcygeal[en.wikipedia.org]
Sex distribution
Age distribution

Pathophysiology

  • Josep Dalmau and colleagues in the Department of Neurology at the University of Pennsylvania published a series of papers documenting a link between encephalitis and ovarian teratomas. 1-5 The pathophysiologic connection is thought to be the presence[mdedge.com]
  • Color Doppler US (CDUS) and Doppler spectrum analysis is helpful for understanding of the pathophysiology of fetal tumors and the accompanying fetal hemodynamic changes.[e-ultrasonography.org]
  • Most of the malignant tumors produce markers that can be serologically assessed. [1, 2, 3, 4, 5, 6, 7] Pathophysiology Several theories about the origin of these tumors are recognized.[emedicine.medscape.com]
  • Pathophysiology [ edit ] Teratomas belong to a class of tumors known as nonseminomatous germ cell tumor (N.S.G.C.T.). All tumors of this class are the result of abnormal development of pluripotent cells: germ cells and embryonal cells.[en.wikipedia.org]

Prevention

  • In general, chemotherapy can make it possible to delay, decrease or eliminate the radiation normally given to the entire brain and spine in an attempt to prevent relapse distant from the site of the primary tumor.[childhoodbraintumor.org]
  • With the decrease in swelling, doctors hope that permanent brain damage may be prevented. Testing. Meredith noticed that Janell had a hemolytic anemia.[abc.go.com]
  • […] prognosis for astrocytoma and choroid plexus papilloma is good, [7] but that for congenital intracranial teratoma is extremely poor, with a mortality rate around 90%. [6] Thus, early diagnosis of immature intracranial teratomas is extremely important to prevent[ijpmonline.org]
  • Treatment may include (alone or in combination): Surgery (to remove the tumor and involved organs) Chemotherapy Radiation Bone marrow transplantation Supportive care (for the effects of treatment) Hormonal replacement (if necessary) Antibiotics (to prevent[stanfordchildrens.org]
  • Hopefully this finding will suggest something that can be done to prevent obstetricians from having to tell patients having Cesarean sections that they’ve given birth to baseballs. But at least my baseballs didn’t have hair and teeth in them.[blogs.plos.org]

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