METHODS: A computerized database search identified 41 patients presenting to Indian University with pure teratoma in the orchiectomy specimen. [ncbi.nlm.nih.gov]

• Lymphadenopathy

  In those shown by CT to have retroperitoneal lymphadenopathy, the distribution of disease correlates closely with that reported in the literature following retroperitoneal lymphadenectomy. [ncbi.nlm.nih.gov]

  Therefore, patients can be safely managed with observation after orchiectomy followed by chemotherapy for recurrent tumors. [11] Retroperitoneal lymph node dissection is reserved for children with persistent retroperitoneal lymphadenopathy or increased [emedicine.medscape.com]

  Bilateral inguinal lymphadenopathy was also present. Contrast-enhanced computed tomography scan (CECT) of abdomen confirmed a large heterogenous mass in the right scrotal sac with few specks of calcification and hemorrhage. [ccij-online.org]

  Thorough abdominal examination specifically for masses or tenderness, inguinal and supraclavicular lymphadenopathy, gynecomastia and chest auscultation for evidence of metastatic disease should be performed [ 9 ]. [omicsonline.org]

• Soft Tissue Mass

  We suggest that for a man with testicular cancer who has a soft tissue mass, metastasis of soft tissue from testicular cancer and other solid malignancies should be considered in the differential diagnosis of a soft tissue mass together with primary soft [ncbi.nlm.nih.gov]

• Leg Swelling

  Advanced symptoms include: neck mass; coughing or trouble breathing; stomach problems such as nausea, vomiting, bleeding or anorexia; lower back pain; bone pain; nerve pain or leg swelling. [testicularcancersociety.org]

• Aspiration

  An experienced cytopathologist can easily diagnose seminoma metastasis in fine needle aspiration smears. Primary germinal tumors of testis are diagnosed through fine needle aspiration of lymph node metastasis especially from retroperitoneum. [oncolex.org]

  Fine-needle aspiration cytology of an endometrioid-like variant of yolk sac tumor. Diagn Cytopathol 1992;8:600-4. 4. Ulbright TM. [ijpmonline.org]

  Procedures: Fine-needle aspiration or core biopsy can be used to differentiate benign from malignant mediastinal masses in 90% of cases. Histologic Findings: In cystic teratomas, the outside of the tumor wall usually is lined with native tissue. [csh.org.tw]

• Ulcer

  A past medical history of duodenal ulcer was a significant risk factor for ulceration after radiotherapy (p 0.04) whereas a past history of abdominal surgery was not (p 0.8). [ncbi.nlm.nih.gov]

  Genitourin Med 69:400–403 PubMed Google Scholar Borgström E (1988) Penile ulcer as complication in self-induced papaverine erections. [link.springer.com]

• Suggestibility

  This case suggests that even the benign-appearing components of these tumors have malignant potential. Because these tumors are malignant, they should be treated by radical orchiectomy and radical retroperitoneal dissection. [ncbi.nlm.nih.gov]

• Aggressive Behavior

  In cases of entirely mature benign teratomas, orchidectomy may suffice, although in adults even apparently completely mature teratomas can have aggressive behavior, largely due to the potential of small components of embryonal carcinoma cells 1-3. [radiopaedia.org]

  In the ‘anaplastic’ variant of spermatocytic seminoma, 99 named for its uniformly atypical cells with nucleolar prominence ( Figure 16 ) (although lacking clinical evidence of aggressive behavior), the relatively monomorphous tumor cell population may [nature.com]

• Testicular Mass

  […] cystic testicular mass that proved to be a mixed germ cell tumor Mixed germ cell tumor: Mixed germ cell tumor mainly embryonal cell carcinoma Mixed germ cell tumor: Testis tumor with calcifications that proved to be a mixed germ cell tumor Mixed germ [ultrasoundcases.info]

  Clinically the patient presents with a testicular mass, testicular atrophy, testicular pain and back pain following metastasis to the vertebra. Investigation findings include high level of alkaline phosphatase, elevated human chorionic gonadotropin. [differencebetween.com]

  On exam, the physician discovers a hard, testicular mass on the right testis. On further questioning, the patient remarks that he first noticed it 6 months ago, but did not think he needed to have it examined since it wasn't painful. [medbullets.com]

• Scrotal Mass

  Physical examination revealed a right scrotal mass the size of child's head and several skin tumors. Right high orchiectomy and resection of skin tumors were performed. [ncbi.nlm.nih.gov]

  Rhabdomyosarcoma is the most common malignant tumor (17%) and may arise from the distal spermatic cord and appear as a scrotal mass or hydrocele. [10] These tumors have a bimodal distribution and occur in boys aged 3-4 months and in teenagers. [emedicine.medscape.com]

  Paratesticular rhabdomyosarcoma Paratesticular rhabdomyosarcomas usually present with an enlarging painless scrotal mass. [pediatricurologybook.com]

• Retrograde Ejaculation

  Here's a good starter list of possible problems: Infertility due to retrograde ejaculation. If the doctor cuts a nerve during the surgery, and it is very easy to do this, you will lose the ability to ejaculate normally. [thetcrc.org]

Review Topic QID: 106375 5 No further workup, instruct patient to return if symptomatic M1 Select Answer to see Preferred Response PREFERRED RESPONSE 2 Sorry, this question is for PEAK Premium Subscribers only ARTICLES (4) VIDEOS (1) Topic COMMENTS (12 [medbullets.com]

Testicular Cancer Workup. Available online at . Accessed July 2014. Motzer RJ, Agarwal N, Beard C, et al. Testicular Cancer. Journal of the National Comprehensive Cancer Care Network. 2009;7:672-693. Available online at . Accessed July 2014. [labtestsonline.it]

WORKUP Lab Studies: Elevated serum alpha-fetoprotein (AFP) and beta-human chorionic gonadotropin (HCG) levels may be indicative of malignancy, as these values are within reference ranges in most patients with benign teratomas. [csh.org.tw]

For teratomas, which cannot be distinguished clinically from other tumours, the patient workup should be the same as would be for the evaluation of any other suspicious testicular masses. [omicsonline.org]

Surgical treatment of teratoma in childhood is controversial, especially when it occurs bilaterally. In this report we discuss testis sparing surgery as the treatment for this disease. [ncbi.nlm.nih.gov]

[…] does not appear to affect prognosis. [ncbi.nlm.nih.gov]

(Etiology) The cause of Teratoma of the Testis is unknown. [dovemed.com]

Epidemiologic, etiologic, and pathologic features. Cancer (Philad.) 32, 1186–1201 (1973) CrossRef Google Scholar Mostofi, F. K., Price, E. B. Jr.: Tumors of the male genital system. Atlas of tumor pathology, fasc. 8, second series. Washington, D. [link.springer.com]

Unknown etiology -- possibly trauma immune reaction to sperm. [6] Microscopic Features: [6] Granulomas /- necrosis. /-Destruction of seminiferous tubules. Prominent collagen fibrosis. DDx: GCNIS (ITGCN). Seminoma. [librepathology.org]

Epidemiologic, etiologic, and pathologic features. Cancer. 1973, 32: 1186-1201. 10.1002/1097-0142(197311)32:5 3.0.CO;2-8. [jmedicalcasereports.biomedcentral.com]

This data briefing examines the epidemiology of the main types of testicular tumours, and considers the likely impact of such a change in coding. [ncin.org.uk]

Introduction Testicular tumors can be of germ cell or non-germ cell origin germ cell origin are the majority (95%) and are more commonly malignant non-germ cell origin usually benign Epidemiology incidence most common cancer in men between 15-35 years [medbullets.com]

Testes Overview Epidemiology [ edit ] 7000 cases/yr. Most common neoplasm in men ages 15-35. [en.wikibooks.org]

Epidemiology These account for 1-2% of all tumours The incidence is very low, with prevalence being about 5 per 100 000 They are the most common cancer in men ages 15-35 Ovarian cell cancers are far less common than testicular cancers Teratomas tend to [almostadoctor.co.uk]

These groups are defined by epidemiological characteristics, histological composition and chromosomal constitution (Table 1). [atlasgeneticsoncology.org]

Definition / general Tumor originating from germ cells with more than one embryonic germ layer Pathophysiology Postpubertal type associated with germ cell neoplasia in situ (GCNIS) and chromosome 12p amplification ( Med Surg Urol 2014;3:1 ) Thought to [pathologyoutlines.com]

Pathophysiology: Teratomas are made up of a variety of parenchymal cell types representative of more than a single germ layer, usually all 3. Arising from totipotential cells, these tumors typically are midline or para-axial. [csh.org.tw]

Pathophysiology [ edit ] Teratomas belong to a class of tumors known as nonseminomatous germ cell tumor (N.S.G.C.T.). All tumors of this class are the result of abnormal development of pluripotent cells: germ cells and embryonal cells. [en.wikipedia.org]

The extent of para-aortic metastases could be clearly defined, even when bulk replacement of nodes prevented definition by lymphography. [ncbi.nlm.nih.gov]

[…] from GCNIS Prepubertal is not associated with GCNIS or chromosome 12p amplification ( Med Surg Urol 2014;3:1 ) Prepubertal type significantly less likely to metastasize or recur Diagnosis Ultrasound is used to evaluate a testicle mass Avoid biopsies to prevent [pathologyoutlines.com]

[…] tumors Removal of the testis Debulking surgery to reduce tumor size, followed by chemotherapy Clotting the vessels in the tumor (embolization) Chemotherapy Radiotherapy Undertaking treatment of underlying conditions How can Teratoma of the Testis be Prevented [dovemed.com]

Men diagnosed with a teratoma, with no evidence of metastases (spread of the disease), either have two courses of adjuvant chemotherapy to prevent any spread, or they may be monitored (surveillance), with frequent blood tests and x-rays. [healthtalk.org]