Presentation
Hirsutism is present in up to 25% reproductive aged women and is most often caused by polycystic ovary syndrome. [ncbi.nlm.nih.gov]
Entire Body System
- Abdominal Obesity
However, only after comparing men with TD and abdominal obesity with men without TD and no abdominal obesity, we found a 3.30 fold increased risk of death (HR = 3.30, 95% CI = 1.21-8.71). [ncbi.nlm.nih.gov]
Too much estrogen slows testosterone production, and with less testosterone, more abdominal obesity occurs and even more estrogen is made, a vicious cycle of emasculation. [njurology.com]
Although testosterone loss is common as men age, it is often associated with diabetes, abdominal obesity, sexual dysfunction, depression and other adverse conditions. [healio.com]
- Rigor
Yet, despite the mythic properties popularly associated with T, in every rigorous scientific study to date there is no significant correlation in healthy men between levels of T and sexual desire. [aeon.co]
"History compels us to ensure that decisions about genetic superiority are supported by objective, rigorous and reproducible data." [bbc.com]
Although some men believe that taking testosterone medications may help them feel younger and more vigorous as they age, few rigorous studies have examined testosterone therapy in men who have healthy testosterone levels. [mayoclinic.org]
When it comes to testosterone and aggression, the authors say that some of the most rigorous studies (double-blind, placebo-controlled) show no connection. [nature.com]
- Plethora
It will focus on the molecular signaling pathways governed by mAR activation, discuss latest attempts to elucidate the molecular identity of mAR, address the plethora of cell responses initiated by mAR and evaluate the potential role of mAR and mAR-specific [doi.org]
AskMen features a plethora of articles on the topic of becoming better in bed. And it's not just to attract readers. When it comes to relationships, sex is important. And testosterone has a big effect on our sexual health. [askmen.com]
In most cases, not all but most, acne is caused by using gear you shouldnt be using in the first place; were talking about the plethora of underground gear that is nothing short of garbage. [steroid.com]
- Underweight
Likewise, for men who are underweight, getting your weight up to a healthy level can also have a positive effect on the hormone. 3. Stay Active. Testosterone adapts to your body's needs, Yu says. [webmd.com]
Respiratory Medicine. 98(9): 906-13 Weisberg J, Wanger J, Olson J, Streit B, Fogarty C, Martin T, Casaburi R (2002) Megestrol acetate stimulates weight gain and ventilation in underweight COPD patients. [ncbi.nlm.nih.gov]
Respiratoric
- Deepening of Voice
During puberty, testosterone helps build a man's muscles, deepens his voice, and boosts the size of his penis and testes. In adulthood, it keeps a man's muscles and bones strong and maintains his interest in sex. [webmd.com]
It deepens the voice, increases muscle growth, promotes facial and body hair, and spurs the sex drive. Testosterone also is associated with personality traits related to power and dominance. [theatlantic.com]
During a boy's puberty, testosterone causes the growth of body hair, muscle development, and deepening of the voice. In adult men, it controls sex drive, maintains muscle mass, and helps make sperm. [medlineplus.gov]
- Aspiration
University of Texas professor John Hoberman, author of an exhaustively researched book, Testosterone Dreams, argues that the fact that testosterone helps people meet societal aspirations is why it’s so difficult to regulate. [fusion.net]
After dilution with 0.01 N nitric acid (serum: 1:10; urine: 1:2), the samples were directly aspirated into the AAS system. [doi.org]
M.E.W. has received funding from: VA Merit Review 001 9U54AG062319-06 CO-SCORE, Corcept Therapeutics, Inc., Novartis LC1699C2301, and Cancer League of Colorado; has received honoraria or consultation fees from Pfizer to review ASPIRE grant applications [academic.oup.com]
Cardiovascular
- Vascular Disease
We suggest that androgen deficiency is associated with IR, T2D, MetS, and with increased deposition of visceral fat, which serves as an endocrine organ, producing inflammatory cytokines and thus promoting endothelial dysfunction and vascular disease. [ncbi.nlm.nih.gov]
Skin
- Hirsutism
To examine the significance of the non-SHBG-bound testosterone (i.e. free plus albumin bound) in hyperandrogenism, we obtained single blood samples from 17 normal women, 20 regularly menstruating but hirsute women, and 20 oligoamenorrheic hirsute women [ncbi.nlm.nih.gov]
To examine the significance of the non-SHBG-bound testosterone ( i.e. free plus albumin bound) in hyperandrogenism, we obtained single blood samples from 17 normal women, 20 regularly menstruating but hirsute women, and 20 oligoamenorrheic hirsute women [doi.org]
- Alopecia
Skin cells express all androgen metabolizing enzymes required for the independent cutaneous synthesis of androgens and the development of hyperandrogenism-associated conditions and diseases, such as seborrhea, acne, hirsutism and androgenetic alopecia [ncbi.nlm.nih.gov]
Finner and Jerry Shapiro, Androgenetic Alopecia, Endocrinology and Metabolism Clinics of North America, 36, 2, (379), (2007). [doi.org]
[…] by granulosa-theca cell tumors of the ovary, especially in mares. testosterone cyclopentylpropionate, testosterone cypionate, testosterone propionate esters with a long period of activity. testosterone-responsive dermatosis a bilaterally symmetrical alopecia [medical-dictionary.thefreedictionary.com]
- Acne Vulgaris
Zouboulis, Acne vulgaris Acne vulgaris, Der Hautarzt, 10.1007/s00105-009-1830-1, 61, 2, (107-114), (2010). Andrew T. [doi.org]
Psychiatrical
- Increased Libido
Potential benefits of therapy include increased libido, improved sexual function, improved mood and well-being, and increased muscle mass and bone density; however, there is little or mixed evidence confirming clinically significant benefits. [ncbi.nlm.nih.gov]
All have seen an increase in physical and mental drive, better moods, increased libido, and a decrease in belly fat. [menstclinic.com]
The hormone testosterone stands for typically male attributes – it fosters the forming of the sexual characteristics, increases libido and muscle building. Women also have this sex hormone, but to a much lesser extent. [uni-bonn.de]
Children exposed to the hormone have experienced enlargement of the penis or clitoris, growth of pubic hair, increased libido, and aggressive behavior. [consumerreports.org]
Testosterone promotes attention, memory, spatial reasoning, and energy — essentially, it makes you sharper — and, of course, it increases libido and muscle mass. [bigthink.com]
Neurologic
- Difficulty Concentrating
Testosterone deficiency can also be the cause of these following symptoms: decreased intensity of orgasm; decreased sensation in the genital organs; inability to obtain or maintain an erection; depressed mood; difficulty concentrating. [brunet.ca]
Symptoms There are several symptoms that are associated with a deficiency in testosterone in men: Reduced libido Difficulty obtaining or maintaining an erection Difficulty concentrating or making decisions Poor results from exercise programs Increase [urmc.rochester.edu]
- Forgetful
Forget the Supplements. Finally, although you're likely to encounter online ads for testosterone-boosting supplements, you aren't likely to find any that will do much good. [webmd.com]
They forget about the fact that they are 50 pounds overweight," Fisch said. "Unfortunately, there's no money to be made telling people to sleep longer and get a better lifestyle." [nbcnews.com]
Who can forget Marion Jones relinquishing her medals from the 2000 Olympics after admitting to using performance-enhancing steroids? This unfortunate trend has overshadowed the beneficial side of these hormones. [health.howstuffworks.com]
Sweet and Spicy Sauce Forget all those sugar-laden sauces, and stick with this low-carb, low-calorie Sweet and Spicy Sauce recipe that still packs just as much flavor! [testshock.com]
- Perseveration
Perseverance is key since testosterone deficiency cannot be cured; it requires taking medication every day. [brunet.ca]
Urogenital
- Sexual Dysfunction
[…] treat low libido and sexual dysfunction in women for over 40 y. [ncbi.nlm.nih.gov]
Sexual dysfunction should be seen as a marker for other health issues. "The penis is the dipstick of the body's health," Fisch said. [nbcnews.com]
[…] treat low libido and sexual dysfunction in women for over 40 y. [doi.org]
Physicians should discuss whether to initiate testosterone treatment in men with age-related low testosterone with sexual dysfunction who want to improve sexual and erectile function based on the potential benefits, harms, costs, and patient preferences [eurekalert.org]
- Clitoromegaly
We describe an 11.5-year-old girl with a 9-month history of voice deepening, mild hirsutism, minor acne, increased growth velocity, weight gain, and clitoromegaly. [ncbi.nlm.nih.gov]
Sartori Sanchez Bachega and Andrea Dardis, The Presence of Clitoromegaly in the Nonclassical Form of 21-Hydroxylase Deficiency Could Be Partially Modulated by the CAG Polymorphic Tract of the Androgen Receptor Gene, PLOS ONE, 11, 2, (e0148548), (2016) [doi.org]
Abnormally high testosterone levels in women may cause the over-development of typically male sex characteristics and may result in: Hirsutism (excess hair growth, for example on the face or chest); Acne; Male balding pattern; Clitoromegaly (enlargement [healthengine.com.au]
Systemic testosterone therapy for postmenopausal women, in doses that approximate physiological testosterone concentrations for premenopausal women, is associated with mild increases in acne and body/facial hair growth in some women, but not with alopecia, clitoromegaly [academic.oup.com]
Workup
Endocrine workup revealed elevated levels of adrenal androgens and adrenal precursors. Mutation analysis confirmed a non-classical 21-hydroxylase deficiency, that is, a mild form of congenital adrenal hyperplasia (CAH). [ncbi.nlm.nih.gov]
Available online at https://emedicine.medscape.com/article/922038-workup#c6. Accessed March 2018. (Updated 2018 March). Male Hypogonadism. ARUP Laboratories. Available online at https://arupconsult.com/content/hypogonadism-male. Accessed March 2018. [labtestsonline.it]
If an adult male's testosterone levels are below 300 ng/dL, a doctor may do a workup to determine the cause of low testosterone, according to the American Urological Association. Low testosterone levels could be a sign of pituitary gland problems. [healthline.com]
[…] testosterone replacement; evaluate patients who report symptoms of pain, edema, warmth, and erythema in the lower extremity for DVT and those who present with acute shortness of breath for PE; if VTE suspected, discontinue testosterone and initiate appropriate workup [reference.medscape.com]
This is usually part of an infertility workup in men and women. Hormonal Supplementation Testosterone is a potent steroid hormone whose chemical formulation is C19-H28-O2. Testosterone is also known as 17-beta-hydroxy-4-androstene-3-one. [verywellhealth.com]
Urine
- Urine 17 Ketosteroids Increased
thyroxine-binding globulin: decreased levels Urine creatine and creatinine: decreased excretion Urine 17-ketosteroids: increased excretion Drug-herbs. [medical-dictionary.thefreedictionary.com]
Serum
- Testosterone Increased
Muscle morphometry showed no significant increase in muscle fiber diameter. These studies suggest that testosterone increases muscle mass by increasing muscle protein synthesis. [ncbi.nlm.nih.gov]
We hypothesize that testosterone levels in the brain are depleted as a normal consequence of male aging and that low brain levels of testosterone increase the risk of developing Alzheimer disease (AD). [dx.doi.org]
- Androgens Increased
Low levels of endogenous androgens increase the risk of atherosclerosis in elderly men: the Rotterdam study. [ahajournals.org]
J Clin Endocrinol Metab 85 : 1026 – 1031 35 Hak AE, Witteman JCM, de Jong FH, Geerlings MI, Hofman A, Pols HAP 2002 Low levels of endogenous androgens increase the risk of atherosclerosis in elderly men: The Rotterdam Study. [academic.oup.com]
Low levels of endogenous androgens increase the risk of atherosclerosis in elderly men: the Rotterdam study. J Clin Endocrinol Metab 87 : 3632–3639, 2002. [dx.doi.org]
H. (2001) Posttraining androgens’ enhancement of cognitive performance is temporally distinct from androgens’ increases in affective behavior. Cogn Affect Behav Neurosci. 1, 172–82. PubMed CrossRef Google Scholar 32. Frye C. A., Edinger K. [doi.org]
Treatment
What is the treatment for low testosterone? In males, the treatment for low-T is based on two approaches. [emedicinehealth.com]
However, this treatment was not effective, so we changed the treatment to testosterone enanthate because of his symptoms with late-onset hypogonadism. [ncbi.nlm.nih.gov]
Prognosis
When in combination, TS, SHBG and BMI, affected prognosis in different ways depending on menopausal status. [ncbi.nlm.nih.gov]
Etiology
Female sexual dysfunction is a complex problem with multiple overlapping etiologies. Androgens play an important role in healthy female sexual function, especially in stimulating sexual interest and in maintaining desire. [ncbi.nlm.nih.gov]
Conclusions: The present study demonstrates an association between alcohol drinking and self-reported sober-state aggression, which implies that the etiology of alcohol misuse and aggressive behavior may involve common biological and/or social factors [doi.org]
Epidemiology
Author information 1 Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, Quebec, Canada; Centre for Clinical Epidemiology, Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Quebec [ncbi.nlm.nih.gov]
Samuli Helle, Women With Long Menstrual Cycles Have More Daughters, Epidemiology, 10.1097/01.ede.0000346251.65625.22, 20, 2, (312-313), (2009). William H. [doi.org]
We cannot assume that testosterone replacement will ameliorate the increased risk seen in these epidemiological studies. [ahajournals.org]
Pathophysiology
Obesity, diabetes, hypogonadism, and specific hormone and metabolic profiles have been implicated in the pathophysiology of CVD. The evolving role of androgens in MetS and CVD is of paramount importance. [ncbi.nlm.nih.gov]
Prevention
How is low testosterone prevented? Low-T that is caused by genetic factors cannot be prevented, nor can low-T be prevented if the underlying cause is a disease caused by inherited genetic factors or necessary treatments such as chemotherapy. [emedicinehealth.com]
Testosterone: A "male hormone" -- a sex hormone produced by the testes that encourages the development of male sexual characteristics, stimulates the activity of the male secondary sex characteristics, and prevents changes in them following castration [medicinenet.com]
Secondary Prevention, Testosterone, Treatment Outcome, Venous Thrombosis < Back to Listings [acc.org]