Hirsutism is present in up to 25% reproductive aged women and is most often caused by polycystic ovary syndrome. [ncbi.nlm.nih.gov]

• Noncompliance

  […] concentrations, and seemingly unpredictable response requires close monitoring and careful follow up and suggests this modality of therapy may not be appropriate for a substantial number of hypogonadal patients, but this strategy warrants consideration in noncompliant [ncbi.nlm.nih.gov]

  Bureau of voluntary noncompliance seminar—anabolic steroids. NABP Newsl. 1988; 17:110-1. 119. Thompson PD, Cullinane EM, Sady SP et al. Contrasting effects of testosterone and stanozolol on serum lipoprotein levels. JAMA. 1989; 261:1165-8. 120. [drugs.com]

• Deepening of Voice

  During puberty, testosterone helps build a man's muscles, deepens his voice, and boosts the size of his penis and testes. In adulthood, it keeps a man's muscles and bones strong and maintains his interest in sex. [webmd.com]

  […] of voice Menstrual irregularities Acne Weight gain Boys may also need a testosterone levels test. [medlineplus.gov]

  It deepens the voice, increases muscle growth, promotes facial and body hair, and spurs the sex drive. Testosterone also is associated with personality traits related to power and dominance. [theatlantic.com]

• Hemianopsia

  Bitemporal hemianopsia was diagnosed by an ophthalmologist, but no other symptoms were reported. Neurosurgical evaluation was otherwise normal. [ncbi.nlm.nih.gov]

  Other symptoms that may be associated with low testosterone include gynecomastia, history of infertility/difficulty conceiving, visual field changes (bitemporal hemianopsia), and anosmia. [auanet.org]

• Hirsutism

  To examine the significance of the non-SHBG-bound testosterone (i.e. free plus albumin bound) in hyperandrogenism, we obtained single blood samples from 17 normal women, 20 regularly menstruating but hirsute women, and 20 oligoamenorrheic hirsute women [ncbi.nlm.nih.gov]

  To examine the significance of the non-SHBG-bound testosterone ( i.e. free plus albumin bound) in hyperandrogenism, we obtained single blood samples from 17 normal women, 20 regularly menstruating but hirsute women, and 20 oligoamenorrheic hirsute women [doi.org]

• Alopecia

  […] resulting from inhibition of 5α-reductases with drugs, such as finasteride and dutasteride, to block transformation of T into 5α-DHT in the course of treatment of benign prostatic hyperplasia (BPH) and male pattern hair loss, also known as androgenetic alopecia [ncbi.nlm.nih.gov]

  In addition, in 42 of 55 females, testosterone was lower than the upper limit of the ID/GC-MS range (0.50–2.55 nmol/L) as measured in normally menstruating women 19–35 years of age with no evidence of hirsutism, acne, or alopecia and taking no oral contraceptives [doi.org]

  […] by granulosa-theca cell tumors of the ovary, especially in mares. testosterone cyclopentylpropionate, testosterone cypionate, testosterone propionate esters with a long period of activity. testosterone-responsive dermatosis a bilaterally symmetrical alopecia [medical-dictionary.thefreedictionary.com]

• Acne Vulgaris

  Zouboulis, Acne vulgaris Acne vulgaris, Der Hautarzt, 10.1007/s00105-009-1830-1, 61, 2, (107-114), (2010). Andrew T. [doi.org]

• Acneiform Eruption

  Three men receiving testosterone and one man receiving placebo had acneiform eruptions; these men may have assumed themselves to be receiving testosterone. [doi.org]

• Nipple Discharge

  Breast cancer was diagnosed in three women in the testosterone groups between 4 and 12 months after treatment initiation ( Table 2 ), one of whom reported in retrospect a bloody nipple discharge before randomization. [dx.doi.org]

• Bloody Nipple Discharge

  Breast cancer was diagnosed in three women in the testosterone groups between 4 and 12 months after treatment initiation ( Table 2 ), one of whom reported in retrospect a bloody nipple discharge before randomization. [dx.doi.org]

• Increased Libido

  Potential benefits of therapy include increased libido, improved sexual function, improved mood and well-being, and increased muscle mass and bone density; however, there is little or mixed evidence confirming clinically significant benefits. [ncbi.nlm.nih.gov]

  All have seen an increase in physical and mental drive, better moods, increased libido, and a decrease in belly fat. [menstclinic.com]

  The hormone testosterone stands for typically male attributes – it fosters the forming of the sexual characteristics, increases libido and muscle building. Women also have this sex hormone, but to a much lesser extent. [uni-bonn.de]

  Children exposed to the hormone have experienced enlargement of the penis or clitoris, growth of pubic hair, increased libido, and aggressive behavior. [consumerreports.org]

  Testosterone promotes attention, memory, spatial reasoning, and energy — essentially, it makes you sharper — and, of course, it increases libido and muscle mass. [bigthink.com]

• Type A Personality

  Central serous chorioretinopathy (CSR) is a serous detachment of the neurosensory retina commonly associated with male sex, Type-A personality and corticosteroid use. [ncbi.nlm.nih.gov]

• Bitemporal Hemianopsia

  Bitemporal hemianopsia was diagnosed by an ophthalmologist, but no other symptoms were reported. Neurosurgical evaluation was otherwise normal. [ncbi.nlm.nih.gov]

  Other symptoms that may be associated with low testosterone include gynecomastia, history of infertility/difficulty conceiving, visual field changes (bitemporal hemianopsia), and anosmia. [auanet.org]

• Sexual Dysfunction

  KEYWORDS: hypogonadism; infertility; sexual dysfunction; testicular volume; testosterone [ncbi.nlm.nih.gov]

  Sexual dysfunction should be seen as a marker for other health issues. "The penis is the dipstick of the body's health," Fisch said. [nbcnews.com]

  Female sexual dysfunction is a complex problem with multiple overlapping etiologies. [doi.org]

• Clitoromegaly

  We describe an 11.5-year-old girl with a 9-month history of voice deepening, mild hirsutism, minor acne, increased growth velocity, weight gain, and clitoromegaly. [ncbi.nlm.nih.gov]

  Abnormally high testosterone levels in women may cause the over-development of typically male sex characteristics and may result in: Hirsutism (excess hair growth, for example on the face or chest); Acne; Male balding pattern; Clitoromegaly (enlargement [healthengine.com.au]

  Sartori Sanchez Bachega and Andrea Dardis, The Presence of Clitoromegaly in the Nonclassical Form of 21-Hydroxylase Deficiency Could Be Partially Modulated by the CAG Polymorphic Tract of the Androgen Receptor Gene, PLOS ONE, 11, 2, (e0148548), (2016) [doi.org]

  Systemic testosterone therapy for postmenopausal women, in doses that approximate physiological testosterone concentrations for premenopausal women, is associated with mild increases in acne and body/facial hair growth in some women, but not with alopecia, clitoromegaly [academic.oup.com]

• Vaginal Bleeding

  Vital signs, weight, and any vaginal bleeding were recorded at each visit. Blood samples were collected at weeks 24 and 52 for laboratory measurements. [dx.doi.org]

• Oligomenorrhea

  A 23-year-old nulliparous woman was found to have an ovarian tumor when she visited her primary doctor for virilization and oligomenorrhea. Magnetic resonance imaging revealed a solid left ovarian tumor 40 mm in size. [ncbi.nlm.nih.gov]

Endocrine workup revealed elevated levels of adrenal androgens and adrenal precursors. Mutation analysis confirmed a non-classical 21-hydroxylase deficiency, that is, a mild form of congenital adrenal hyperplasia (CAH). [ncbi.nlm.nih.gov]

If an adult male's testosterone levels are below 300 ng/dL, a doctor may do a workup to determine the cause of low testosterone, according to the American Urological Association. Low testosterone levels could be a sign of pituitary gland problems. [healthline.com]

[…] testosterone replacement; evaluate patients who report symptoms of pain, edema, warmth, and erythema in the lower extremity for DVT and those who present with acute shortness of breath for PE; if VTE suspected, discontinue testosterone and initiate appropriate workup [reference.medscape.com]

This is usually part of an infertility workup in men and women. Hormonal Supplementation Testosterone is a potent steroid hormone whose chemical formulation is C19-H28-O2. Testosterone is also known as 17-beta-hydroxy-4-androstene-3-one. [verywellhealth.com]

[…] testosterone products; these observations have included patients with and without polycythemia; evaluate signs or symptoms consistent with DVT or PE; if venous thromboembolic event suspected, discontinue treatment with testosterone and initiate appropriate workup [rxlist.com]

• Urine 17 Ketosteroids Increased

  17-ketosteroids: increased excretion Drug-herbs. [medical-dictionary.thefreedictionary.com]

• Testosterone Increased

  We hypothesize that testosterone levels in the brain are depleted as a normal consequence of male aging and that low brain levels of testosterone increase the risk of developing Alzheimer disease (AD). [doi.org]

  In prostate cancer patients, the level of total serum testosterone increased with age. In conclusion, total testosterone is not a statistically significant predictive factor for pathological Gleason score and pathological stage. [ncbi.nlm.nih.gov]

• Androgens Increased

  Low levels of endogenous androgens increase the risk of atherosclerosis in elderly men: the Rotterdam study. [ahajournals.org]

  Low levels of endogenous androgens increase the risk of atherosclerosis in elderly men: the Rotterdam study. J Clin Endocrinol Metab 87 : 3632–3639, 2002. [dx.doi.org]

  J Clin Endocrinol Metab 85 : 1026 – 1031 35 Hak AE, Witteman JCM, de Jong FH, Geerlings MI, Hofman A, Pols HAP 2002 Low levels of endogenous androgens increase the risk of atherosclerosis in elderly men: The Rotterdam Study. [academic.oup.com]

  H. (2001) Posttraining androgens’ enhancement of cognitive performance is temporally distinct from androgens’ increases in affective behavior. Cogn Affect Behav Neurosci. 1, 172–82. PubMed CrossRef Google Scholar 32. Frye C. A., Edinger K. [doi.org]

• Hyperviscosity

  Other possible risks include worsening symptoms of benign prostatic hypertrophy, liver toxicity, hyperviscosity, erythrocytosis, worsening untreated sleep apnea or severe heart failure. [ncbi.nlm.nih.gov]

  […] hematocrit determinations in patients receiving long-term therapy. 117 123 133 135 157 161 162 Perform hematocrit determinations 3–6 months after therapy initiation and annually thereafter. 133 135 157 161 186 187 188 189 190 192 Some clinicians consider hyperviscosity [drugs.com]

• Alternaria

  In vivo, testosterone attenuated Alternaria-extract-induced IL-5 and IL-13 ILC2 numbers and lung eosinophils by intrinsically decreasing lung ILC2 numbers, as well as by decreasing expression of IL-33 and thymic stromal lymphopoietin (TSLP), ILC2-stimulating [ncbi.nlm.nih.gov]

However, this treatment was not effective, so we changed the treatment to testosterone enanthate because of his symptoms with late-onset hypogonadism. [ncbi.nlm.nih.gov]

Treatment Contraception 1 1, 2 Completed Treatment Gender Dysphoria 1 1, 2 Completed Treatment Healthy Males 2 1, 2 Completed Treatment Hypogonadism 1 1, 2 Not Yet Recruiting Treatment Spinal Cord Injuries (SCI) 1 1, 2 Recruiting Treatment Female Infertility [drugbank.ca]

When in combination, TS, SHBG and BMI, affected prognosis in different ways depending on menopausal status. [ncbi.nlm.nih.gov]

Conclusions: The present study demonstrates an association between alcohol drinking and self-reported sober-state aggression, which implies that the etiology of alcohol misuse and aggressive behavior may involve common biological and/or social factors [doi.org]

Female sexual dysfunction is a complex problem with multiple overlapping etiologies. Androgens play an important role in healthy female sexual function, especially in stimulating sexual interest and in maintaining desire. [ncbi.nlm.nih.gov]

Author information 1 Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, Quebec, Canada; Centre for Clinical Epidemiology, Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Quebec [ncbi.nlm.nih.gov]

Samuli Helle, Women With Long Menstrual Cycles Have More Daughters, Epidemiology, 10.1097/01.ede.0000346251.65625.22, 20, 2, (312-313), (2009). William H. [doi.org]

We cannot assume that testosterone replacement will ameliorate the increased risk seen in these epidemiological studies. [ahajournals.org]

Obesity, diabetes, hypogonadism, and specific hormone and metabolic profiles have been implicated in the pathophysiology of CVD. The evolving role of androgens in MetS and CVD is of paramount importance. [ncbi.nlm.nih.gov]

How is low testosterone prevented? Low-T that is caused by genetic factors cannot be prevented, nor can low-T be prevented if the underlying cause is a disease caused by inherited genetic factors or necessary treatments such as chemotherapy. [emedicinehealth.com]