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Thalamic Neoplasm

Thalamic Tumor


Presentation

  • This case highlights an unusual presentation and challenging diagnosis of a dAVF and the importance of pursuing the correct diagnosis.[ncbi.nlm.nih.gov]
  • Outcome in Patients With High-Grade Tumors Nine patients presented with high-grade tumors in our series ( Table 2 ).[thejns.org]
  • Those presenting in unusual locations pose a diagnostic challenge. Pre-operative diagnosis, however, may change the line of management.[content.iospress.com]
  • Methods We reviewed the clinical presentation, surgical approach, perioperative mortality and morbidity, and outcomes of 111 operated patients (71 males, 40 females; mean age at presentation, 33.4   13.2 years) with unilateral thalamic tumor.[springermedizin.de]
  • METHODS: The records of 69 children who presented with a thalamic tumor between 1989 and 2003 were retrospectively reviewed.[ncbi.nlm.nih.gov]
Thalamic Pain
  • Possible syndromes Loss of visual Field (sectoranopsia) Reduction of the sensitivity of the body (hemihypesthesia) Decreased sensitivity to pain on one side of the body (hemihypalgesia) Decreased taste Thalamic pain 8.[braininjury-explanation.com]
  • Additionally, a phenomenon known as thalamic pain – where the thalamus overreacts to pain impulses from the contralateral side – has been observed subsequent to a thalamic infarct.[kenhub.com]
Fixed Pupils
  • Two postoperative deaths occurred: The first patient underwent operation with a GCS score of 3 and bilateral fixed pupils, and died during the immediate postoperative period.[thejns.org]
Generalized Seizure
  • The boy presented with headache, generalized seizures and right-sided paresis of recent onset. Computed tomography and magnetic resonance imaging revealed a mass in the left thalamus with hydrocephalus.[content.iospress.com]

Workup

  • We present a patient with a provisional diagnosis of bilateral thalamic neoplasm based on clinical history and an advanced imaging workup including MR spectroscopy. Subsequent biopsy suggested venous congestion, hypoxia, and edema without neoplasia.[ncbi.nlm.nih.gov]

Treatment

  • After all tests are completed, doctors will be able to outline the best treatment options. What are thalamic and hypothalamic astrocytoma treatment options? A number of treatments may be recommended for thalamic or hypothalamic astrocytomas.[danafarberbostonchildrens.org]
  • Ankylosing spondylitis - Current protocols for diagnosis and treatment options. Wegener granulomatosis - Autoimmune etiology and clinical course.[netdoc.com]
  • The aim of this study was to determine whether clinical and neuroimaging features could guide treatment, and to what extent these features, together with histological diagnosis and treatment modalities, influenced survival.[ncbi.nlm.nih.gov]
  • In the past, the outcome of surgical treatment for thalamic tumors was poor.[thejns.org]
  • Conclusions Surgical treatment of adult thalamic tumors must be individualized according to tumor location. Low-grade tumors and total/subtotal resection seem to be predictors of better surgical outcomes.[springermedizin.de]

Prognosis

  • The thalamopeduncular tumors were mostly pilocytic astrocytomas, which had a good prognosis following surgery.[ncbi.nlm.nih.gov]
  • These are known to have poor prognosis, irrespective of their histopathology. There are two views regarding the origin.[neurology.org]
  • Jentzsch et al made an effort to correlate the tumor volume response to radiation therapy to the prognosis. [17] They found a post treatment increase in tumor size in 4 patients with low grade gliomas which did not correlate with poor prognosis.[neurologyindia.com]
  • I realize we don't have all of the details needed at this point to make a prognosis, but would be interested in hearing stories from anyone with similar tumors.[csn.cancer.org]
  • What’s the Prognosis for Those With Gliomas? High-grade gliomas are fast-growing tumors. with a poor prognosis, especially for older patients.[webmd.com]

Etiology

  • Wegener granulomatosis - Autoimmune etiology and clinical course. Diabetes - disease and management information, including diagnosis, typical treatment plans and diabetes supplies.[netdoc.com]
  • Patients were excluded if there was a neoplastic, infectious, or inflammatory etiology.[ajnr.org]
  • Bilateral thalamic infarction: clinical, etiological and MRI correlates. Acta Neurol Scand 2001; 103: 35–42. Reilly M, Connolly S, Stack J, Martin EA, Hutchinson M.[bioj.org]

Epidemiology

  • SMARCA4 genes is required for the diagnosis of atypical teratoid / rhabdoid tumor (ATRT) Tumors with similar morphology but lacking this mutation are classified as CNS embryonal tumor with rhabdoid features ICD coding C71 : malignant neoplasm of brain Epidemiology[pathologyoutlines.com]
  • Definition / general Pilocytic means "hair-like," due to long, bipolar processes Most common CNS neoplasm of childhood Better prognosis than diffuse types, particularly if resectable (such as cerebellar tumors) WHO grade I Epidemiology Most common CNS[pathologyoutlines.com]
  • "Epidemiological survey of central nervous system germ cell tumors in Canadian children". J. Neurooncol. 82 (3): 289–95. doi : 10.1007/s11060-006-9282-2. PMID 17120159. Packer RJ, Cohen BH, Cooney K, Coney K (2000). "Intracranial germ cell tumors".[en.wikipedia.org]
Sex distribution
Age distribution

Pathophysiology

  • Doran Infant Locomotor Development 1997 2016-07-18 The follicle-stimulating hormone receptor: biochemistry, molecular biology, physiology, and pathophysiology. M. Simoni et al.[carta.anthropogeny.org]
  • Cerebellar glioblastomas: pathophysiology, clinical presentation and management. Acta Neurochir, v. 151, p. 653-75, 2009. [ Links ] 12. GOPALAKRISHNAN, C. V. et al. A retrospective study of primary cerebellar glioblastoma multiforme in adults.[scielo.br]

Prevention

  • With Aneurysms, Size Doesn't Matter Preventing ACL Injury through Strengthening Exercises Preventing ACL Injury through Strengthening Exercises - Women Fitness When Stroke Affects the Thalamus The thalamus is a busy place in the human brain, and a stroke[pinterest.de]
  • Hospital for Sick Children Health A-Z Search a complete list of child health articles expand_more View All Drug A-Z Search a list of articles about medications expand_more View All Learning Hubs Browse a complete list of content groups Healthy Living & Prevention[aboutkidshealth.ca]
  • These views open a newer channel for prophylactic radiation covering MI and third ventricle to prevent the intact thalamus and hence improve the prognosis of the patients. Disclosure: Dr. Gogia has nothing to disclose. Dr.[neurology.org]
  • The steroid is usually given with an acid blocker to prevent stomach irritation or ulcers and can be associated with increased appetite (and occasionally other side effects) when given for more than a few days.[curesearch.org]
  • If we did, then we would be able to treat them more effectively, or even prevent them occurring at all.[brainstrust.org.uk]

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