Presentation
Thus, we report a rare presentation of thelaziasis, that is, periocular involvement. This case presentation is first of its kind in the Indian literature. [ncbi.nlm.nih.gov]
Musculoskeletal
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Fracture
Orbital subperiosteal abscess and blindness complicating a minimally displaced zygomatic complex fracture. Br J Oral Maxillofac Surg 1995;33:185–188. 14. Choudhury AR. Thelaziasis. Am J Ophthalmol 1969;67:773–774. 15. [synapse.koreamed.org]
Skin
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Flushing
When the presence of nematodes was confirmed, the conjunctival fornix was flushed with a saline solution for parasite recovery and counting, and the dogs were treated appropriately. [doi.org]
Treatment is based on the mechanical removal of the worms by flushing the eyes. [parasite-journal.org]
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Petechiae
Early signs including rheum and light ocular discharge are frequently followed by conjunctivitis, petechiae, oedema, keratitis and epiphora [ 13 ]. Treatment is based on the mechanical removal of the worms by flushing the eyes. [parasite-journal.org]
Eyes
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Photopsia
She had no photopsia or field loss, and no pain, redness, or discharge. She had no past ocular or medical history, and was otherwise well. On examination she had a visual acuity of 6/60 in the right eye, and 6/6 in the left eye. [doi.org]
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Anterior Uveitis
Intraocular localization ofOnchocerca lupiadult worm in a dog with anterior uveitis: A case report. Veterinary Ophthalmology, Vol. 19, Issue. 3, p. 245. CrossRef Google Scholar Maia, C. Catarino, A. L. Almeida, B. Ramos, C. [doi.org]
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Conjunctival Injection
Later five and seven adult worms were removed every 4 weeks and the conjunctival injection improved with no parasites detected after the final extraction. [synapse.koreamed.org]
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Blurred Vision
A 41-year-old woman experienced swelling, itching sensation and occasional blurred vision of the right eye 2 weeks after a small group of flies swarmed her eye while she was hiking. [ncbi.nlm.nih.gov]
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Blepharospasm
The most frequent signs observed in infected dogs included conjunctivitis (74% of the positive cases), epiphora (70%), pruritus (35%), purulent exudation (33%), and blepharospasm (20%). [parasite-journal.org]
Neurologic
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Irritability
[…] causative organism in thelaziasis, a well described condition affecting the external eye. 1 It is primarily a parasite of the conjunctiva in dogs, and is also found in rabbits and humans. 2 Its presence in the conjunctival sac causes lacrimation and irritation [doi.org]
Case summary A 71-year-old male visited the ophthalmic clinic, complaining of itching, a foreign body sensation, and irritation in the right eye. He was previously diagnosed with Thelazia callipaeda infection, 3 months prior, at another hospital. [synapse.koreamed.org]
The clinical signs of thelaziosis are related to the presence of irritant foreign-bodies, i.e., the nematodes, in the conjunctival sac. [parasite-journal.org]
Workup
Microbiology
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Gnathostoma Spinigerum
Gnathostoma spinigerum, a close relative of Thelazia, is quite frequently found within the eye and causes major tissue destruction. [doi.org]
Gnathostoma spinigerum mitochondrial genome sequence: a novel gene arrangement and its phylogenetic position within the class chromadorea. Sci. Rep. 5:12691. doi: 10.1038/srep12691 PubMed Abstract CrossRef Full Text Google Scholar Liu, G. [frontiersin.org]
Treatment
The efficacy of treatments was established by eye inspection and parasite viability and vitality after 1, 5 and 9 days after animal treatments (groups A and B) and after 9 days only in untreated animals (group C). [ncbi.nlm.nih.gov]
Allocation and treatment At inclusion, each dog was randomly allocated to one of the two treatment groups. [parasite-journal.org]
Treatment with ivermectin is recommended for cases of thelaziasis, but in the absence of preoperative and postoperative symptoms of inflammation due to infestation, pharmacological treatment was not commenced in this case. [doi.org]
Etiology
Until now, the etiological agent of all human thelaziasis reported in China was identified as T. callipaeda, but few cases reported detailed morphological characteristics. [frontiersin.org]
The seasonality of human thelaziasis may impair correct etiologic diagnosis of this disease because spring and summer are the seasons in which allergic conjunctivitis (e.g., by pollens) occurs most frequently. [doi.org]
Epidemiology
CONCLUSIONS: The Asian population of T. callipaeda has a high level of genetic diversity, but further studies should be performed to explore the biology, ecology and epidemiology of T. callipaeda. [ncbi.nlm.nih.gov]
Descriptive epidemiology 2. Clinical features 3. Distribution map 4. Images 5. Global status and status in every relevant country 6. [books.google.es]
Molecular epidemiological survey on the vectors of Thelazia gulosa, Thelazia rhodesi and Thelazia skrjabini (Spirurida: Thelaziidae). Parasitology 127, 365 – 373. ROSSI, L. & BERTAGLIA, P. ( 1989 ). [doi.org]
Prevention
Key words: Thelazia callipaeda / eyeworm / prevention / dog / milbemycin oxime / Europe W. [doi.org]
Thirty dogs were treated with milbemycin oxime monthly from June to November with the recommended dose rate for the prevention of heartworm disease ( or 0.5mg/kg), 30 dogs served as untreated controls. [ncbi.nlm.nih.gov]
To prevent infection, the fly vector should be avoided in areas in which the parasite is endemic. The patient has not reported any recurrence since the removal of the parasites. [nejm.org]