Presentation
Case Presentation: A 12 year old obese male presented to the Pediatric clinic for evaluation of dyspnea on exertion. Mother reported snoring and restless sleep since 7 years of age. [shmabstracts.com]
Doctor's Order Required Michigan law requires that a valid order signed by an authorized person be presented before any laboratory test or procedure can be conducted. [midmichigan.org]
Phlebotomy, known also as bloodletting or venesection, is a major therapeutic procedure that has been performed by physicians in various civilisations since antiquity up to the present 1, 2. [phlebotomytechnicianschools.net]
Studies with JAK inhibitors are presently ongoing. [aetna.com]
Entire Body System
- Pain
Pain., fatigue, pain) Adherence Always Burden A little hard to take Dosage: Weekly Advice & Tips: Drink PLENTY of water. I am also excessively hungry and tired on blood draw days. [patientslikeme.com]
Too much iron in the blood causes a toxic overload which can lead to organ damage, joint pain and long-term health concerns. [chop.edu]
This patient no longer requires narcotic analgesics for pain, has resolution of constitutional symptoms, and has not required further hospitalizations for vaso-occlusive pain crises. [aetna.com]
- Anemia
It also emphasizes that anemia per se is not a contraindication to embarking on a therapeutic phlebotomy program. [nejm.org]
You may develop anemia. Anemia is a low number of red blood cells or a low amount of hemoglobin in your red blood cells. Hemoglobin is a protein that helps carry oxygen throughout your body. Red blood cells use iron to create hemoglobin. [drugs.com]
Disclosures: Off Label Use: Use of hydroxyurea in children with sickle cell anemia. © 2011 by The American Society of Hematology [bloodjournal.org]
At anytime during treatment you experience symptoms of heart irregularities or severe abdominal pain or symptoms of anemia, alert your physician immediately. Symptoms of anemia can often be mistaken by a patient as symptoms of iron overload. [irondisorders.org]
- Weakness
DISCHARGE INSTRUCTIONS: Contact your healthcare provider if: You feel weak or more tired than usual. Your heart is beating faster than usual. You have shortness of breath. You have pale skin or cold hands and feet. You cannot think clearly. [drugs.com]
But I digress… During the procedure or right after it, low blood pressure, which may lead to feeling light headed, weak, or even fainting can occur. Bruising can occur. Some symptoms can persist beyond the treatment. [hemochromatosishelp.com]
People with polycythemia usually experience fatigue, weakness, headaches, and hypertension. Polycythemia is a symptom which occurs with a variety of known and sometimes unknown origins. [defymedical.com]
- Swelling
Call Your Doctor Call your doctor if any of these occur: Redness Swelling Persistent bleeding or discharge Pain If you think you have an emergency, call for emergency medical services right away. [winchesterhospital.org]
[…] every 4 weeks,face and ear bleeding therapy was 1 times a week, Both of the two group were treated 20 weeks.Then we analysed and compared the changes of the subjective symptom score(scorching, pruritus, dry),objective symptom score(erythema, papule, swell [big5.oversea.cnki.net]
As the disease progresses, symptoms typical of emphysema or cirrhosis include: Fatigue Chronic cough Swelling of the ankles and feet Jaundice (this is more commonly associated with cirrhosis) Fluid in the abdomen (ascites) How Is Alpha-1 Antitrypsin Deficiency [webmd.com]
- Falling
When ferritin falls more rapidly following a phlebotomy, there is likely some other reason for the fast rate other than the blood donation. [hemochromatosis.org]
In fact 0.45 is used more Won't bother going in to other options as clearly my knowledge is falling upon deaf ears who want to argue over how to represent a ratio of cellular matter to plasma Share this post Link to post Share on other sites Look all [uk-muscle.co.uk]
People suspected with polycythaemia can fall under the following criteria: Increase in haematocrit, more than 52% in men or 48% in women More than 18.5 g/dL increase in haemoglobin level in men and 16.5 g/dL increase in women Increase in red blood cell [ephlebotomytraining.com]
Respiratoric
- Dyspnea
Case Presentation: A 12 year old obese male presented to the Pediatric clinic for evaluation of dyspnea on exertion. Mother reported snoring and restless sleep since 7 years of age. [shmabstracts.com]
The major medical benefit of this therapy is the prevention or reversal of liver fibrosis; some patients report decreased dyspnea, pigmentation, fatigue, or arthralgia, or improved control of diabetes mellitus. [bloodjournal.org]
Gastrointestinal
- Overeating
STUDY DESIGN AND METHODS: TP procedures over 13 months were evaluated at a 142-bed rural hospital. The hospital had a Food and Drug Administration variance for a hereditary hemochromatosis (HH) donor program. [ncbi.nlm.nih.gov]
The blood should be collected at a rate that the patient can tolerate, generally over 10-15 minutes. Observe the patient for adverse reactions during and immediately following the procedure. [healthcare.uiowa.edu]
If systolic is over 180 or under 90, if diastolic is over 100 or under 50, the patient must be admitted to the ER and seen by the ER physician prior to being drawn and again before leaving. [chalab.org]
Cardiovascular
- Hypertension
People with polycythemia usually experience fatigue, weakness, headaches, and hypertension. Polycythemia is a symptom which occurs with a variety of known and sometimes unknown origins. [defymedical.com]
What You Need to Know About Successfully Reducing High Blood Pressure High blood pressure, or hypertension, is one of those diseases, if left untreated, can kill you. [geisingerbloodcenter.org]
Therapeutic efficiency of phlebotomy in posttransplant hypertension associated with erythrocytosis. Clin Nephrol. 1993; 40 :241–3. [ PubMed ] 30. Vlahakos DV, Marathias KP, Agroyannis B, Madias NE. Posttransplant erythrocytosis. [ncbi.nlm.nih.gov]
Because of this, it can help some people who suffer from hypertension. It may also help to lower blood pressure and dangerous cholesterol levels. Therapeutic phlebotomy gives your spleen a break! [phlebotomyexaminer.com]
- Hypotension
Notify his primary care provider if he has hypotension or signs and symptoms of dehydration; she may cancel the procedure or order intravenous replacement fluids. [journals.lww.com]
Elderly patients with some cardiovascular compromise or cerebral vascular complications should have the volume replaced with saline solution after each procedure to avoid postural hypotension. [emedicine.medscape.com]
Interestingly, phlebotomy was only associated with self-limited adverse events (prevalence: 3.5%), such as hypotension, dizziness, syncope, headache, and weakness. [ncbi.nlm.nih.gov]
Intolerance of phlebotomy Decreasing the phlebotomy interval to every 2 weeks is necessary in some patients, especially women. 9 In patients who report hypotension or dizziness, the volume of oral salt drinks can be increased; rarely, an intravenous saline [bloodjournal.org]
Skin
- Skin Disease
Porphyria Cutanea Tarda – A photsensitive skin disease. Polycythemia Secondary to Arterio-venous Fistulae – This is an increase in the number of blood cells and an abnormal passageway that’s between an artery and a vein. [ephlebotomist.com]
Musculoskeletal
- Arthritis
Over time, people with hereditary hemochromatosis may develop liver cirrhosis, liver cancer, heart disease, diabetes, arthritis, hypothyroidism, and impotence. If iron overload is untreated, it can be fatal. [nybloodcenter.org]
In later stages, the excess iron can lead to arthritis, diabetes, liver disease, heart problems and other chronic conditions. [chop.edu]
It also increases the risk of arthritis (osteoarthritis, osteoporosis), cirrhosis of the liver or liver cancer, diabetes mellitus, depression, gall bladder disease, hypothyroidism, hypogonadism, irregular heart beat or heart attack, impotence, infertility [ephlebotomytraining.com]
Neurologic
- Stroke
/phlebotomy for the reduction of recurrent stroke and improvement in iron overload management in children with sickle cell anemia (SCA) and history of overt stroke. [bloodjournal.org]
Abstract Serial phlebotomy was performed on sixty children with sickle cell anaemia, stroke and transfusional iron overload randomized to hydroxycarbamide in the Stroke With Transfusions Changing to Hydroxyurea trial. [ncbi.nlm.nih.gov]
[…] experienced an initial stroke. [aetna.com]
This latest study was prompted by earlier research which suggested regular blood donors have lower cholesterol and reduced risk of heart problems and stroke. [defymedical.com]
- Headache
People with polycythemia usually experience fatigue, weakness, headaches, and hypertension. Polycythemia is a symptom which occurs with a variety of known and sometimes unknown origins. [defymedical.com]
Interestingly, phlebotomy was only associated with self-limited adverse events (prevalence: 3.5%), such as hypotension, dizziness, syncope, headache, and weakness. [ncbi.nlm.nih.gov]
Symptoms of anemia or iron overload can include: fatigue, heart arrhythmia, headache, sensitivity to cold, shortness of breath, dizziness and restless legs syndrome. Lab tests are needed to distinguish between the two. [irondisorders.org]
- Irritability
They also check to see if your child is anxious, irritable, dizzy, pale, or thirsty. If your child has any of these problems, the nurse will stop the procedure and tell the doctor. The procedure will not start again until the doctor says it can. [stjude.org]
- Excitement
The changes induced by the treatment were assessed by clinical scores, biological tests, and neurophysiological study of cortical excitability using transcranial magnetic stimulation techniques. [aetna.com]
Workup
Tough to answer without a full workup of some kind, and maybe you have done that, I am not familiar with your posting history. Stress in marriage, work, anything, can cause a lot of problems. [allthingsmale.com]
Serum
- Thrombocytosis
PV may also be suspected among the following patients: More than 18 g/dL elevated haemoglobin level in men and more than 16 g/dL in women More than 52% haematocrit in men and more than 47% in women Splenomegaly with or without leucocytosis and thrombocytosis [ephlebotomytraining.com]
Thrombocythemia and Thrombocytosis. National Heart Lung and Blood Institute [On-line information]. Available online at http://www.nhlbi.nih.gov/health/dci/Diseases/thrm/thrm_what.html. Accessed March 2009. Mayo Clinic Staff (2009 February 3). [labtestsonline.it]
Tefferi (2012) stated that PV and ET are myelo-proliferative neoplasms (MPN) primarily characterized by erythrocytosis and thrombocytosis, respectively. [aetna.com]
Patients with thrombotic tendencies or those who develop thrombocytosis after phlebotomy should be treated with marrow suppression; consider anagrelide in younger patients (aged 50-70 y). [emedicine.medscape.com]
Treatment
Reviewing these diagnoses will help nurses understand why phlebotomy is an important part of treatment. [ncbi.nlm.nih.gov]
TP treatment is not available at mobile blood drives. 6. All TP treatment performed at BloodworksNW centers is subject to cost recovery through the patient’s insurer or from the patient. The cost per TP treatment will be $103.00. 7. [bloodworksnw.org]
[…] performed by our Registered Nurse • Q&A discussion during treatment with experienced clinician • No wait time • One-on-one care during treatment • Appointment Reminders when routine treatments are needed • Average time for treatment: 1 hour Further reading [defymedical.com]
Initiation of therapeutic phlebotomy is based on serum ferritin and does not require liver biopsy Treatment has centered on cytoreduction by therapeutic phlebotomy and/or treatment with cytoreductive pharmaceuticals such as hydroxyurea or [alpha]-interferon [medical-dictionary.thefreedictionary.com]
Prognosis
What Is the Prognosis for People With Inherited Liver Diseases? With proper treatment, hemochromatosis and alpha-1 antitrypsin deficiency disease are usually not fatal. However, complications associated with the diseases can be. [webmd.com]
Prognosis and treatment of polycythemia vera. Last reviewed June 2013. UpToDate Inc., Waltham, MA. Wang WC, Dwan K. Blood transfusion for preventing primary and secondary stroke in people with sickle cell disease. [aetna.com]
JAK2V617F mutational status and allele burden have little influence on clinical phenotype and prognosis in patients with post-polycythemia vera and post-essential thrombocythemia myelofibrosis. Haematologica. 2009 Jan. 94(1):144-6. [Medline]. [emedicine.medscape.com]
Pathophysiology
Normal iron metabolism and the pathophysiology of iron overload disorders. Clinic Biochem Rev. 2006; 27 :5–16. [ PMC free article ] [ PubMed ] 47. McLaren CE, McLachlan GJ, Halliday JW, et al. [ncbi.nlm.nih.gov]
Hereditary hemochromatosis: Pathophysiology, diagnosis, and management. Crit Care Nurs Clin North Am. 2008;20(2):191-201, vi. Finazzi G, Barbui T. Evidence and expertise in the management of polycythemia vera and essential thrombocythemia. [aetna.com]
Prevention
The first 2 trials addressed the use of chronic transfusion to prevent primary stroke; the third utilized the drug hydroxycarbamide (hydroxyurea) and phlebotomy to prevent both recurrent (secondary) stroke and iron over-load in patients who had already [aetna.com]
Tell him to move slowly afterward when changing positions or standing, to prevent light-headedness, faintness, and a rapid drop in blood pressure. Tell him to drink plenty of liquids over the next 24 hours to replace lost fluid. [journals.lww.com]
People with alpha-1 antitrypsin deficiency are able to produce this protein; however, the disease prevents it from entering the bloodstream and it instead accumulates in the liver. [webmd.com]