Case presentation: We report a girl which presented with sensorineural deafness treated with a hearing prosthesis, insulin requiring diabetes, macrocytic anemia, treated with thiamine (100 mg/day). [pubmed.ncbi.nlm.nih.gov]

However, our patient presented diabetic ketoacidosis. [latunisiemedicale.com]

• Seizure

  Our patient presented retinitis pigmentosa, nystagmus, seizure and development delay; these features are more common in respiratory chain deficiency. [latunisiemedicale.com]

• Agitation

  He could not speak; he had hearing loss and was an agitated and disturbed boy. He was the third child of the family. His two sisters died at the age of two and three years. [latunisiemedicale.com]

After two months of the combined treatment a complete resolution of anemia was observed. Insulinotherapy was successfully stopped at one month after beginning treatment with thiamine. [latunisiemedicale.com]

Keywords: anemia; diabetes mellitus; hearing loss; megaloblastic; sensorineural; thiamine; treatment. [pubmed.ncbi.nlm.nih.gov]