A patient who sustained thiopental extravasation and received local injection of lidocaine and local application of EMLA (Eutectic Mixture of Local Anesthetics) for treatment with excellent results is presented hereunder. [ncbi.nlm.nih.gov]

• Acute Intermittent Porphyria

  Contraindications Absolute Contraindications Absence of suitable veins for intravenous administration, hypersensitivity (allergy) to barbiturates and variegate porphyria (South African) or acute intermittent porphyria. [druglib.com]

  Contraindications : Acute intermittent porphyria Liver and kidney disease Severe pulmonary insufficiency. e.g. emphysema· Obstructive sleep apnoea. For detailed query or in case of uncertainty, Always consult your doctor or pharmacist. [doctoralerts.com]

  Acute attacks of variegate or acute intermittent porphyria may be triggered in susceptible individuals. Drug interactions Other cerebral depressants may augment the action of thiopental. [apps.who.int]

  CONTRAINDICATIONS Absolute Contraindications Absence of suitable veins for intravenous administration, hypersensitivity (allergy) to barbiturates and variegate porphyria (South African) or acute intermittent porphyria. [rxlist.com]

• Pharyngitis

  We concluded that, when propofol, rather than thiopental, is used for the induction of anesthesia, it results in a lower incidence of early pharyngeal morbidity and postoperative nausea and vomiting after the insertion of a LMA. [ncbi.nlm.nih.gov]

• Formication

  Cartridges were washed using 10% methanol in ammonium acetate buffer (50mM, pH 7) before elution with mobile phase comprising 0.1% formic acid in water and acetonitrile with a flow rate of 0.55mL/min using a 7.2min run time. [ncbi.nlm.nih.gov]

• Pneumoperitoneum

  Creation of pneumoperitoneum resulted in a significant increase in IOP which remained elevated throughout the operation in both groups. [ncbi.nlm.nih.gov]

• Lymphopenia

  However, barbiturate-mediated neuroprotection correlates with lymphopenia, which increases the risk of infection. The mechanisms by which barbiturates lead to lymphopenia remain to be determined. [ncbi.nlm.nih.gov]

Early diagnosis and treatment may bear a favorable outcome. [ncbi.nlm.nih.gov]

CONCLUSION: Because this multicenter study has an epidemiological character, the prevalence of i.v. thiopental use in psychiatric emergency settings in Japan is considered to be 8.0%. [ncbi.nlm.nih.gov]

The epidemiology of major depressive disorder: Results from the National Comorbidity Survey Replication (NCS-R). JAMA 2003;289:3095-105. 2. Sadock BJ, Sadock VA, Ruiz P, Kaplan HI. Kaplan and Sadock's Comprehensive Textbook of Psychiatry. [annals.in]

Alfentanil 55 μg/kg was needed to prevent increases in ABP postintubation >10% above baseline with 95% probability. One individual needed a bolus of vasopressor postintubation. [ncbi.nlm.nih.gov]

Alendronate slows bone loss while increasing bone mass, which may prevent bone fractures. Alendronate is used to treat or prevent postmenopausal osteoporosis and steroid-induced osteoporosis. [emedicinehealth.com]