Presentation
A patient who sustained thiopental extravasation and received local injection of lidocaine and local application of EMLA (Eutectic Mixture of Local Anesthetics) for treatment with excellent results is presented hereunder. [ncbi.nlm.nih.gov]
Entire Body System
- Acute Intermittent Porphyria
Contraindications Absolute Contraindications Absence of suitable veins for intravenous administration, hypersensitivity (allergy) to barbiturates and variegate porphyria (South African) or acute intermittent porphyria. [druglib.com]
Contraindications : Acute intermittent porphyria Liver and kidney disease Severe pulmonary insufficiency. e.g. emphysema· Obstructive sleep apnoea. For detailed query or in case of uncertainty, Always consult your doctor or pharmacist. [doctoralerts.com]
Acute attacks of variegate or acute intermittent porphyria may be triggered in susceptible individuals. Drug interactions Other cerebral depressants may augment the action of thiopental. [apps.who.int]
CONTRAINDICATIONS Absolute Contraindications Absence of suitable veins for intravenous administration, hypersensitivity (allergy) to barbiturates and variegate porphyria (South African) or acute intermittent porphyria. [rxlist.com]
Respiratoric
- Pharyngitis
We concluded that, when propofol, rather than thiopental, is used for the induction of anesthesia, it results in a lower incidence of early pharyngeal morbidity and postoperative nausea and vomiting after the insertion of a LMA. [ncbi.nlm.nih.gov]
Skin
- Formication
Cartridges were washed using 10% methanol in ammonium acetate buffer (50mM, pH 7) before elution with mobile phase comprising 0.1% formic acid in water and acetonitrile with a flow rate of 0.55mL/min using a 7.2min run time. [ncbi.nlm.nih.gov]
Workup
X-Ray
- Pneumoperitoneum
Creation of pneumoperitoneum resulted in a significant increase in IOP which remained elevated throughout the operation in both groups. [ncbi.nlm.nih.gov]
Serum
- Lymphopenia
However, barbiturate-mediated neuroprotection correlates with lymphopenia, which increases the risk of infection. The mechanisms by which barbiturates lead to lymphopenia remain to be determined. [ncbi.nlm.nih.gov]
Treatment
Early diagnosis and treatment may bear a favorable outcome. [ncbi.nlm.nih.gov]
Epidemiology
CONCLUSION: Because this multicenter study has an epidemiological character, the prevalence of i.v. thiopental use in psychiatric emergency settings in Japan is considered to be 8.0%. [ncbi.nlm.nih.gov]
The epidemiology of major depressive disorder: Results from the National Comorbidity Survey Replication (NCS-R). JAMA 2003;289:3095-105. 2. Sadock BJ, Sadock VA, Ruiz P, Kaplan HI. Kaplan and Sadock's Comprehensive Textbook of Psychiatry. [annals.in]
Prevention
Alfentanil 55 μg/kg was needed to prevent increases in ABP postintubation >10% above baseline with 95% probability. One individual needed a bolus of vasopressor postintubation. [ncbi.nlm.nih.gov]
Alendronate slows bone loss while increasing bone mass, which may prevent bone fractures. Alendronate is used to treat or prevent postmenopausal osteoporosis and steroid-induced osteoporosis. [emedicinehealth.com]