It may result in easy bruising and excessive bleeding from wounds or bleeding in mucous membranes and other tissues A condition in which there is an abnormally small number of platelets in the circulating blood A decrease in the number of platelets in [icd9data.com]

Other symptoms include nosebleeds and easy bruising; sometimes gastrointestinal bleeding, excess menstrual bleeding, or other hemorrhage is observed. Hemorrhage in the brain can have serious consequences. [britannica.com]

Thrombocytopenia is characterized by easy bruising and increased bleeding. [rxlist.com]

bruising, petechiae, bleeding, hematuria, melena Acute ITP (typically in children): following a viral infection Chronic ITP (typically women of childbearing age): insidious onset or incidental finding Diagnosis CBC: normal except for decreased platelet [amboss.com]

disease Platelets become diluted Massive red blood cell replacement or exchange transfusion; stored red blood cells do not contain very many platelets Use or destruction of platelets increases Immune thrombocytopenia HIV infection and other viral infections [msdmanuals.com]

The most common causes of splenomegaly (enlarged spleen) are portal hypertension secondary to liver disease and splenic infiltration with tumor cells, or with macrophages in storage disorders (like Gaucher's disease ). [healthcentral.com]

Platelets get trapped in enlarged spleen in splenomegaly, portal hypertension, Gaucher disease, etc., and cause low platelet count. 1.10. [intechopen.com]

Hemoptysis, hematemesis, hematuria, hematochezia, and melena are rarely the initial symptoms of a bleeding disorder. However, these may be exacerbated by an underlying bleeding disorder. Menstrual history is important. [emedicine.medscape.com]

bleeding gums, epistaxis) at lower platelet counts. Other patients with thrombocytopenia are clinically ill and have multisystem findings (e.g., acute infection, liver disease, TTP/HUS, DIC). [amboss.com]

Key points about ITP in children ITP is a blood disorder with decreased blood platelets, which may result in easy bruising, bleeding gums, and internal bleeding. [stanfordchildrens.org]

People with thrombocytopenia can: bruise easily have nose bleeds or bleeding gums have pinpoint bleeding in the skin that looks like a rash (known as petechiae) have cuts that keep bleeding feel tired In rare cases, dangerous internal bleeding may occur [healthdirect.gov.au]

But if the count drops low enough, a child might have one or more of these problems: easy bruising bleeding gums bleeding from minor wounds or nosebleeds that's hard to stop small red or purple spots on the skin called petechiae (peh-TEE-kee-eye) purple [kidshealth.org]

Possible symptoms include: Severe bruising or bleeding Small red or purple spots (petechiae) on the skin Bleeding gums Nosebleeds Bleeding from a wound that stops and starts again Bloody urine or stool Heavy menstrual flow (women only) How is thrombocytopenia [fairview.org]

At presentation, acquired thrombotic thrombocytopenia purpura in a very young child is commonly misdiagnosed as other conditions like idiopathic thrombocytopenic purpura, Evans syndrome, atypical hemolytic-uremic syndrome, or malignancy. [ncbi.nlm.nih.gov]

"How Is Thrombotic Thrombocytopenic Purpura Treated? - NHLBI, NIH". www.nhlbi.nih.gov. Retrieved 2015-05-20. Thrombocytopenic Purpura: New Insights for the Healthcare Professional: 2013 Edition: ScholarlyPaper. ScholarlyEditions. 2013-07-22. [en.wikipedia.org]

Larger than petechiae, ecchymoses are purple, blue or yellow-green areas of skin that vary in size and shape. [en.wikipedia.org]

Suspect ITP in a child with thrombocytopenia and petechiae following a viral illness! [amboss.com]

A 20-month-old boy presented with a 2-day history of fever and systemic petechiae. There were no abnormal findings except for an extremely low platelet count (8000/μl) on blood examinations. [ncbi.nlm.nih.gov]

[…] thrombocytes Artificial heart valves Use of heart-lung machine Dialysis with extracorporeal circulation Diffusion disorders Splenomegaly Hypothermal anesthesia Laboratory artifact Pseudothrombocytopenia 3 Symptoms In thrombocyte counts below 30,000/µl, petechiae [flexikon.doccheck.com]

The patient was admitted to hematology service with epistaxis, ecchymoses, fever, thrombocytopenia (0.6 x 103/μL) and anemia. His initial diagnosis was idiopathic thrombocytopenic purpura. [ncbi.nlm.nih.gov]

bleeding gums, epistaxis) at lower platelet counts. Other patients with thrombocytopenia are clinically ill and have multisystem findings (e.g., acute infection, liver disease, TTP/HUS, DIC). [amboss.com]

It presents in infancy or in neonates (in severe cases) with patients bruising easily along with further manifestations of thrombocytopenia including epistaxis, petechiae, ecchymoses, or splenomegaly. [enerca.org]

Findings suggestive of intracranial hemorrhage include the following: Headache, blurred vision, somnolence, or loss of consciousness Hypertension and bradycardia, which may be signs of increased intracranial pressure On neurologic examination, any asymmetrical [emedicine.medscape.com]

PGRN deficiency further decreased platelet count in a passive-transfer ITP murine model. By contrast, administration of recombinant PGRN increased platelet count in SCID mice with chronic ITP. [ncbi.nlm.nih.gov]

In addition to a complete medical history and physical examination, laboratory testing of the blood can show decreased platelet counts. [chop.edu]

Thrombocytopenia is a decreased platelet count. Normal platelet count should range from 150,000 to 400,000 per microliter. [youtube.com]

Candida sp.[33]), and Toxoplasma gondii.[32] The severity of thrombocytopenia may be correlated with pathogen type; some research indicates that the most severe cases are related to fungal or gram-negative bacterial infection.[33] The pathogen may be [en.wikipedia.org]