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Thyroid Dysfunction


Presentation

  • CONCLUSIONS: The present study demonstrated a high prevalence of thyroid dysfunction in Mexican elderly people living in the community.[ncbi.nlm.nih.gov]
  • We present a case of thyroid dysfunction in severe OHSS in a patient diagnosed with subclinical hypothyroidism before COH.[ncbi.nlm.nih.gov]
  • The present paper describes the abovementioned mechanisms based on the latest research. We also present a review of some recent original studies evaluating thyroid function in overweight and obese children, including thyroid ultrasound.[ncbi.nlm.nih.gov]
  • In this paper we present two cases in which thyroid disorders were unexpectedly brought to view.[ncbi.nlm.nih.gov]
  • The pathogenesis of autoimmune diseases in patients with Hepatitis C virus infection and interferon therapy is not clear, but usually these disorders are reversible and only require supervision and treatment if clinical or laboratory abnormalities are present[ncbi.nlm.nih.gov]
Transient Hypothyroidism
  • Thyroid dysfunction developed after surgery for glucocorticoid excess in two patients; one with Carney's complex had transient hypothyroidism after bilateral adrenalectomy for PAND, and the other had transient hyperthyroidism due to thyroiditis after[ncbi.nlm.nih.gov]
  • hypothyroidism (at 21 months postpartum in one patient, and 5 months after another pregnancy in the other).[ncbi.nlm.nih.gov]
Abdominal Obesity
  • Subjects with hypothyroidism had significantly higher level of BMI, WC, TC, LDL-C, and higher prevalence of abdominal obesity (84.6%, p Copyright 2017 Diabetes India. Published by Elsevier Ltd. All rights reserved.[ncbi.nlm.nih.gov]
Periodontitis
  • Abstract Thyroid dysfunction causes spreading and development of caries in the teeth and changes in periodontal tissues.[ncbi.nlm.nih.gov]
Mild Cognitive Impairment
  • METHODS: Cognitive performances were examined in 215 participants, including 54 healthy participants, 52 SIVD patients with no dementia (SIVDND), 55 patients with mild cognitive impairment (SVMCI), and 54 patients with vascular dementia (VD).[ncbi.nlm.nih.gov]

Workup

  • Complete thyroid workup was done in 106 patients of SSc which included thyroid function test, antithyroid peroxidase (TPO) antibody, antithyroid-stimulating hormone receptor (TSHR) antibody, antithyroglobulin antibody, and thyroid ultrasound to assess[ncbi.nlm.nih.gov]
  • Apart from TSH, other essential test required to measure thyroid health include: Free T3 Free T4 Thyroid antibodies A full workup of lifestyle and nutritional deficiencies should also address: Food allergies (especially gluten intolerance) Heavy metal[drpompa.com]
  • A fever of unknown origin requires a careful workup.[verywell.com]

Treatment

  • […] of thyroid autoantibodies prior to or during treatment.[ncbi.nlm.nih.gov]
  • Morphological changes of the thyroid gland can be associated with the well-described adverse biochemical effects of treatment with sunitinib and can be a potential marker of the irreversible organ damage.[ncbi.nlm.nih.gov]
  • As illustrated in this case series, in contrast to other causes of auto-immune thyroiditis, hypothyroidism can develop rapidly within 3 months of treatment.[ncbi.nlm.nih.gov]
  • Autoimmune disorders and BRAF mutation were associated with a better clinical response to CTLA4 followed by PD1 treatment.[ncbi.nlm.nih.gov]
  • Amiodarone is an effective medication for the treatment of cardiac arrhythmias.[ncbi.nlm.nih.gov]

Prognosis

  • […] of thyroid hormones (THs) on the cardiovascular system involves the regulation of key processes related to maintenance of cardiac function; however, there are no long-term studies available showing that intervening the TD changes the incidence or the prognosis[ncbi.nlm.nih.gov]
  • In conclusion, early detection and effective treatment of patients affected by thyroid dysfunction is essential to improve their cardiovascular prognosis. Close cooperation between endocrinologists and cardiologists is necessary.[excemed.org]
  • Although, papillary carcinoma is the most common type, it has the best prognosis. In the other hand, the follicular carcinoma is rare and has the worst prognosis [ 50 , 52 ].[omicsonline.org]

Etiology

  • We report the rare case of a patient with adenomyosis who showed thyroid dysfunction of unknown etiology during treatment for endometriosis.[ncbi.nlm.nih.gov]
  • Although pigmentation occurs in the sun exposed areas, the etiology remains unknown and there are no appropriate treatment guidelines. Association with thyroid disorder has been described in various disorders of pigmentation.[ncbi.nlm.nih.gov]
  • We recommend that thyroid dysfunction should be frequently considered as a potential etiology for many of the nonspecific complaints that physicians face daily.[ncbi.nlm.nih.gov]
  • Hypothyroidism: etiology, diagnosis, and management. Med Clin North Am. 2012; 96(2): 203-21. PubMed Carney LA, Quinlan JD, West JM. Thyroid disease in pregnancy. Am Fam Physician. 2014; 89(4): 273-8. PubMed Casey B, de Veciana M.[arupconsult.com]
  • Skin manifestations of thyroid dysfunction may be divided into two main categories: (I) direct action of thyroid hormone on skin tissues, and (II) autoimmune skin disease associated with thyroid dysfunction of autoimmune etiology.[austinpublishinggroup.com]

Epidemiology

  • In future, clinicians should make efforts in documenting similar cases with associated clinical profiles from our part of the world, thereby contributing to the local and regional epidemiology of these syndromes.[ncbi.nlm.nih.gov]
  • This study aimed to establish the reference intervals for FT4, TSH, and thyroid peroxidase antibody (TPO Ab), and identify the epidemiological prevalence of thyroid dysfunction in a Korean pediatric population.[ncbi.nlm.nih.gov]
  • Purpose: Epidemiologic evidence of a relationship between thyroid dysfunction and age-related macular degeneration (AMD) is inconsistent and unclear.[ncbi.nlm.nih.gov]
  • However, epidemiological studies on the association between maternal thyroid dysfunction and long-term child outcomes are observational in design, and are challenged by important methodological aspects. 2017 European Society of Endocrinology.[ncbi.nlm.nih.gov]
  • This call should stimulate thyroidologists working in different areas (from basic research or epidemiology to the frontline of the clinical arena or to those designing public health programs) to be aware of this new outlook.[ncbi.nlm.nih.gov]
Sex distribution
Age distribution

Pathophysiology

  • The exact pathophysiology remains unknown but we discuss several possible mechanisms of sunitinib-induced thyroid shrinkage.[ncbi.nlm.nih.gov]
  • PURPOSE OF REVIEW: The purpose of this review is to provide an update on the current knowledge of the pathophysiology, the mechanisms, and the cardiovascular impact of the different stages of thyroid dysfunction (TD) in heart failure (HF) patients.[ncbi.nlm.nih.gov]
  • Pathophysiology and Diagnosis of Thyroid Disease." Institute of Medicine. 2003. Medicare Coverage of Routine Screening for Thyroid Dysfunction.[nap.edu]
  • Pathophysiology of disease : an introduction to clinical medicine. Hammer, Gary D.,, McPhee, Stephen J. (Eighth ed.). New York. ISBN 9781260026504.[en.wikipedia.org]
  • Pathophysiology/Complications A longitudinal study A longitudinal study Abstract OBJECTIVE —Cross-sectional studies have reported that the risk of thyroid dysfunction in patients with type 1 diabetes is two- to threefold higher than in the general population[care.diabetesjournals.org]

Prevention

  • It is essential to diagnose thyroid dysfunction at an early stage because congenital hypothyroidism (CH) represents one of the most common preventable causes of delayed physical and psychological development, including mental retardation.[ncbi.nlm.nih.gov]
  • Developed By: United States Preventive Services Task Force Healthy People 2020 Topic Area(s): Nutrition and Weight Status Citation: U.S. Preventive Services Task Force. Thyroid Dysfunction: Screening [Internet]. 2015 Mar [cited 2017 Sept 8].[healthypeople.gov]
  • These services, known as preventive services, are intended either to prevent disease (by vaccination) or to detect disease (by diagnostic test) before the symptoms of illness appear.[books.google.com]
  • Alterations of thyroid function in overweight and obese patients cause an increase in energy expenditure, which facilitates weight loss and prevents further weight gain.[ncbi.nlm.nih.gov]
  • Most recently, the United States Preventive Services Task Force did not endorse screening for thyroid dysfunction based on a lack of proven benefit and potential harm of treating those with thyroid dysfunction, which is mostly subclinical disease.[ncbi.nlm.nih.gov]

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