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Thyroid Gland Disorder
Disease Thyroid

Images

WIKIDATA, CC BY 3.0
WIKIDATA, Public Domain
WIKIDATA, CC BY-SA 3.0
WIKIDATA, Public Domain

Presentation

The classic presentation of Graves disease include: 1. Hyperthyroidism 2. Goitre 3. Opthalmopathy 4. Dermopathy (unusual) 5. [sites.google.com]

Thyroid cancer often presents without symptoms and just causes a goiter or nodules that usually will not impact the thyroid's function or cause any pain in the early stages. [self.com]

| N Engl J Med 2018; 379:e23 A 53-year-old man presented to the endocrinology clinic with fatigue and sensitivity to cold. [nejm.org]

Thyroid and Parathyroid Glands Presents the chemistry, synthesis, and secretion of thyroid hormones. Covers hamburger thyrotoxicosis, pregnancy, fetal development, and sodium-iodide. [dmoztools.net]

Patients may have the disease for months or years without noticing a single symptom.4,6 Graves’ disease has a more sudden onset and presents as hyperthyroidism. [thermofisher.com]

Entire Body System

  • Goiter

    In modern-day America, goiters due to iodine deficiency are no longer common because our salt is iodized, but goiters are still a problem in some areas of the world. [study.com]

    E05.2 Thyrotoxicosis with toxic multinodular goiter... E05.20 Thyrotoxicosis with toxic multinodular goiter... E05.21 Thyrotoxicosis with toxic multinodular goiter... [icd10data.com]

    Treatment with thyroid hormone replacement medication (levothyroxine) may be used to decrease the size of the goiter; surgery is needed if the goiter becomes too large and narrows the airway. [verywell.com]

    (B) Toxic goiter: When swelling or enlargement of the thyroid gland results in excess secretion of thyroid hormones, this condition is called toxic goiter (Fig. 12.11). [biologydiscussion.com]

    Toxic nodular goiter or multinodular goiter. Hyperthyroidism caused by toxic nodular goiter is where one or more nodules of the thyroid becomes overactive. The overactive nodules actually act as benign thyroid tumours. [hon.ch]

  • Fatigue

    The following is a list of symptoms typical of a thyroid gland disorder – some are specific to hypothyroidism and others to hyperthyroidism : Fatigue Weight gain or weight loss Changes in heart rate, including increased blood pressure and heart palpitations [ctsinuscenter.com]

    They experience predominantly fatigue but also weight gain, dry skin, cold intolerance, muscle weakness, constipation, eye puffiness, hoarse voice, and poor memory.13The three treatment modalities for hyperthyroidism include:14 1. Medical therapy 2. [thermofisher.com]

    Other autoimmune disorders Emotional or physical stress Pregnancy or recent childbirth Smoking Graves’ Disease Symptoms in Women Common signs and symptoms of Graves’ disease in women include: Irritability Difficulty sleeping Fatigue A rapid or irregular [usa.healthcare.siemens.com]

    Weight loss, rapid heartbeat, anxiety, fatigue, trouble sleeping, tremors and sweating. Hypothyroidism. Thinning hair, weight gain, fatigue, muscle weakness, joint pain, depression and impaired memory. Thyroid cancer. [mayoclinichealthsystem.org]

    Hypothyroidism Hyperthyroidism Weight gain Weight loss Constipation Diarrhea Fatigue Fatigue Hair loss N/A Depression, “brain fog,” or difficulty concentrating Anxiety, difficulty concentrating, nervousness Joint pain Muscle weakness Infertility, missed [todaysdietitian.com]

  • Thyroid Nodule

    An Introduction to Common Thyroid Disorders Thyroid nodules are very common. About 95% of nodules are benign (not cancer), and most do not require any treatment or surgery. [uofmhealth.org]

    Cysts in the thyroid gland can also cause lumps or nodules. A small number of thyroid nodules are the result of thyroid cancer. Most thyroid nodules do not cause symptoms, and most do not produce thyroid hormone. [medicinenet.com]

    Thyroid Nodules A thyroid nodule is a small lump in the thyroid gland. Thyroid nodules are common. These nodules can be either a growth of thyroid tissue or a fluid-filled cyst, which forms a lump in the thyroid gland. [hormone.org]

    A thyroid nodule (NAHD-yool) is a swelling in one section of the thyroid gland. The nodule may be solid or filled with fluid or blood. You may have just one thyroid nodule or many. [womenshealth.gov]

  • Weight Gain

    The following is a list of symptoms typical of a thyroid gland disorder – some are specific to hypothyroidism and others to hyperthyroidism : Fatigue Weight gain or weight loss Changes in heart rate, including increased blood pressure and heart palpitations [ctsinuscenter.com]

    “Lack of hormones decreases metabolism and calorie burning, so you may see gradual but unexplained weight gain,” says Dr. Gharib. [rd.com]

    gain Goiter Constipation Graves’ disease common symptoms include: Anxiety Irritability Sleeping difficulty Fatigue Rapid or irregular heartbeat Heat sensitivity Weight loss, despite normal food intake Goiter Diarrhea Serological testing can help diagnose [thermofisher.com]

    You may experience weight loss as opposed to weight gain. And you may feel anxious as opposed to depressed. The most common difference between the two diseases relates to hormone levels. Hypothyroidism leads to a decrease in hormones. [healthline.com]

    Unintended weight gain and weight loss are common, and both can be a daunting challenge to rectify. [todaysdietitian.com]

  • Myxedema

    CAUSES Myxedema can occur in: Hyperthyroidism, associated with pretibial myxedema and exophthalmos. Pretibial myxedema can occur in 1–4% of patients with Graves' disease, a cause of hyperthyroidism. [slideshare.net]

    This situation may progress to confusion, stupor, or coma (myxedema coma). Myxedema coma is a life-threatening complication in which breathing slows, seizures occur, and blood flow to the brain decreases. [merckmanuals.com]

    Myxedema coma can result in death. Complications: Myxedema coma, the most severe form of hypothyroidism, is rare. It may be precipitated by an infection, illness, exposure to cold, or certain medications. [uclahealth.org]

    Pruritus pretibial myxedema: this is a mucinosis in which excessive amounts of mucopolysaccharides accumulate in the dermis and subcutis of the skin, to cause localized thickening of the pretibial skin. [news-medical.net]

    Initially: Fatigue, constipation, cold intolerance, slowing of mental and physical performance Late: weight gain, forgetfulness, dry and brittle hair, slow reflexes, deep hoarse voice, macroglossia, periorbital puffiness, pretibial myxedema, hypercholesterolemia [quizlet.com]

Respiratoric

  • Hoarseness

    Initially: Fatigue, constipation, cold intolerance, slowing of mental and physical performance Late: weight gain, forgetfulness, dry and brittle hair, slow reflexes, deep hoarse voice, macroglossia, periorbital puffiness, pretibial myxedema, hypercholesterolemia [quizlet.com]

    Facial expressions become dull, the voice is hoarse, speech is slow, eyelids droop, and the eyes and face become puffy. Usually only one blood test is needed to confirm the diagnosis. [merckmanuals.com]

    Hoarse crying. An umbilical hernia. As the disease progresses, infants are likely to have trouble feeding and may fail to grow and develop normally. [mayoclinic.org]

    […] signs include: Fatigue Weakness Intolerance to cold Muscle aches and cramps Constipation Weight gain or difficulty losing weight Poor appetite Goiter (enlarged thyroid gland) Dry, rough skin Coarse hair or hair loss Eye and face swelling Deeper and/or hoarse [medicinenet.com]

    Later symptoms of an underactive thyroid include: a low-pitched and hoarse voice a puffy-looking face thinned or partly missing eyebrows a slow heart rate hearing loss anaemia Page last reviewed: 27/04/2018 Next review due: 27/04/2021 [nhs.uk]

Cardiovascular

  • Tachycardia

    Chapter 243: Focal Atrial Tachycardia -- Section 4: Disorders of the Heart -- Chapter 263: Multiple and Mixed Valvular Heart Disease -- Chapter 264: Congenital Heart Disease in the Adult -- Part 7: Disorders of the Respiratory System -- Section 1: [worldcat.org]

    Firstly, from the reports ( attachment removed to protect patient identity ) it appears that he is having bradycardia and sinus arrhythmia, but no tachycardia. So, according to me, electrophysiology (EP) studies may be helpful, but not necessary. [icliniq.com]

    SIGNS AND SYMPTOMS For Hyperthyroidism:- • Tachycardia • Palpitations • Nervousness • Tremors • Increased BP • Heat intolerance 10.. [slideshare.net]

    Vitiligo is present in less than 5% of pediatric patients with Graves' disease.74 Tachycardia is the most frequent cardiovascular manifestation and usually presents as palpitations; tachycardia during sleep may be helpful in distinguishing tachycardia [glowm.com]

    Unfortunately, unregulated chronotropic and inotropic stimulation of the heart leads to dysrhythmias such as tachycardia and atrial fibrillation. Therefore, patients may complain of frequent palpitations, or syncopal episodes. [kenhub.com]

Skin

  • Alopecia

    Fine, soft hair: this might occur with a diffuse non-scarring form of hair loss (alopecia). Plummer's nails: this is characterized by a concave contouring which raises the nails away from the nail bed. [news-medical.net]

    […] palmar-plantar erythrodysesthesia) English palmar-plantar erythrodysesthesia (PPE) Last Update: 2017-04-26 Usage Frequency: 1 Quality: Maltese Ħakk, Alopeċja, Disturb fid-dwiefer, Sindrome ta’ eritrodisestesija palmari-plantari, Urtikarja English Pruritus, Alopecia [mymemory.translated.net]

Neurologic

  • Headache

    For the last six months, I was having headache and confusion plus slightly increased urination. Last wee... Read Full » Dr. Sagar Ramesh Makode Cardiologist Answer: Hello, Welcome to icliniq.com. [icliniq.com]

    […] loss of appetite, hypertension (high blood pressure), palmar-plantar erythrodysaesthesia syndrome (rash and numbness on the palms and soles), hypothyroidism (an underactive thyroid gland), insomnia (difficulty falling and staying asleep), dizziness, headache [mymemory.translated.net]

    Medscape Education Clinical Briefs, February 2017 The Nurse View: Practice Pearls in the Use of Immune Checkpoint Inhibitors in NSCLC Learn about the use of checkpoint inhibitors in patients with NSCLC Medscape Education Nurses, January 2017 Can Headache [medscape.org]

    These may include: Headache Diarrhea or vomiting Swelling of the breast area Mild rash Changes in vision Mood changes (Depression or anxiety) Discoloured stools or urine Arrhythmia Report these or any other side effects that occur to your doctor as they [4nrx.org]

    Pain, headache, and thermal sensations -- X. The nervous system: B. The special senses. 49. The eye: I. Optics of vision; 50. The eye: II. Receptor and neural function of the retina; 51. The eye: III. Central neurophysiology of vision; 52. [worldcat.org]

Treatment

treatment of thyroid conditions and to improve patient care. [thermofisher.com]

Technavio’s healthcare and life sciences research analysts segment the global thyroid gland disorder treatment market into the following regions: Americas EMEA APAC Thyroid gland disorder treatment in the Americas The thyroid gland disorders treatment [finance.yahoo.com]

Other causes include radioactive iodine treatment, surgical removal of the thyroid gland, radiation treatments of the head and neck and certain medications. [endocrinology.medicine.ubc.ca]

While their cancer is cured, the curative treatment results in hypothyroidism requiring thyroid hormone replacement for life. [thyroid.org]

Prognosis

German : Non-Thyroidal-Illness-Syndrom 1 Definition The non-thyroidal illness syndrome is a characteristic allostatic constellation of pituitary - thyroid feedback control, which is a common bystander of acute or chronic illness and which heralds poor prognosis [flexikon.doccheck.com]

Etiology

Hypothyroidism has multiple etiologies and manifestations. Appropriate treatment requires an accurate diagnosis and is influenced by coexisting medical conditions. [ncbi.nlm.nih.gov]

Published on Nov 6, 2014 Includes a demonstration of the standard thyroid exam, review of the etiologies of goiters, and an overview of the many physical findings of hypothyroidism and hyperthyroidism. [youtube.com]

Introduction: Inflammatory disorders of thyroid gland are a mixture of various disorders characterized by variable clinical presentations, etiologies and treatment modalities. [sites.google.com]

Thyrotoxicosis of other Etiologies Peter Kopp, MD 20. Thyrotropin-Secreting Pituitary Adenomas Paolo Beck-Peccoz, MD, Luca Persani, MD, PhD and Andrea Lania, MD, PhD DISORDERS OF PREGNANCY AND CHILDHOOD 21. [thyroidmanager.org]

Results: Topics addressed include the etiology, epidemiology, clinical and laboratory evaluation, management, and consequences of hypothyroidism. [dx.doi.org]

Epidemiology

Environmental iodine influences the epidemiology of non-malignant thyroid disease. Iodine supplementation of populations with mild-to-moderate iodine deficiency. [ncbi.nlm.nih.gov]

Table 1 Prevalence of previously undiagnosed overt hypothyroidism and incidence of overt hypothyroidism in selected epidemiological surveys of thyroid dysfunction. [academic.oup.com]

We also highlight the pressing need for detailed epidemiological surveys of thyroid dysfunction and iodine status in developing countries. [doi.org]

Descrizione: 1 online resource : illustrations (chiefly color) Contenuti: Hormones and hormone action -- Endocrine autoimmunity -- Evidence-based endocrinology and clinical epidemiology -- Hypothalamus and pituitary gland -- The posterior pituitary (neurohypophysis [worldcat.org]

Pathophysiology

PATHOPHYSIOLOGY Various auto-antibodies may be present against thyroid peroxidase, thyroglobulin and TSH receptors. [slideshare.net]

Sinossi: "The goal of Pathophysiology of Disease: An Introduction to Clinical Medicine is to introduce students to clinical medicine by reviewing the pathophysiologic basis of the symptoms and signs of various common diseases. [worldcat.org]

Pathophysiology and Diagnosis of Thyroid Disease." Institute of Medicine. 2003. Medicare Coverage of Routine Screening for Thyroid Dysfunction. [nap.edu]

Hyperthyroidism The precise pathophysiology that underlies the characteristic cutaneous symptoms of hyperthyroidism still requires elucidation. [news-medical.net]

Pathophysiology of disease : an introduction to clinical medicine. Hammer, Gary D.,, McPhee, Stephen J. (Eighth ed.). New York. ISBN 9781260026504. [en.wikipedia.org]

Prevention

IMAGE: A preventive approach to lifestyle management can effectively control or prevent thyroid disorder. Photograph: Paresh Gandhi/ Rediff.com. [rediff.com]

Preventive Services Task Force] 08/01/2013 Thyroid Nodules 11/15/2009 Screening for Congenital Hypothyroidism: Reaffirmation Recommendation Statement [U.S. [aafp.org]

Though you may not be able to prevent thyroid disease, you can prevent its complications by getting diagnosed right away and following the treatment your doctor prescribes. [healthline.com]

Prevent hand-foot-and-mouth disease It’s contagious, but you can reduce your child’s risk of catching it. Find out what helps. Scabies? Treat everyone! If your child develops scabies, everyone in your household will need treatment. [aad.org]

Unfortunately, sufferers will likely have to be on medication for the rest of their life, but in most cases these drugs do not prevent the patient from leading a normal life and can prevent major complications, such as heart disease and pregnancy issues [diabetes.co.uk]

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