METHODS: We present a case report with details of the initial presentation, laboratory evaluation, surgical and pathologic findings, and subsequent course in a patient with a thyrotropin (thyroid-stimulating hormone or TSH)-secreting adenoma and postoperative [ncbi.nlm.nih.gov]

• Fatigue

  Transient ( influenza -like symptoms, including fever (>100°F/38°C), chills/shivering, myalgia / arthralgia, fatigue/ asthenia / malaise, headache, and chills. [rxlist.com]

  This causes the body’s system to slow down and can lead to symptoms like fatigue, feeling cold, weight gain due to fluid retention, dry skin, and hair loss. If you experience any of these symptoms, talk to your doctor. [synthroid.com]

  Common symptoms of hypothyroidism include fatigue, weakness, weight gain, muscle aches, constipation, slow heart rate and cold intolerance. [labtestsonline.org.au]

  The symptoms of hypothyroidism include fatigue, weakness, and difficulty concentrating. [healthline.com]

  If there is decreased production of thyroid hormones by the thyroid (underactive thyroid or hypothyroidism ), the person may experience symptoms such as weight gain, dry skin, constipation, cold intolerance, and fatigue. [labtestsonline.org]

• Weakness

  In vitro functional studies of the E575K TSHR mutation demonstrated a weak, but significant, increase in constitutive activation of the cAMP pathway. [ncbi.nlm.nih.gov]

  Thyrotropin-Releasing Hormone Deficiency Related Diseases for Thyrotropin-Releasing Hormone Deficiency Symptoms & Phenotypes for Thyrotropin-Releasing Hormone Deficiency Symptoms via clinical synopsis from OMIM: 57 Endocrine: hypothalamic hypothyroidism Misc: weakness [malacards.org]

  Reports of neurologic events, including acute hemiplegia or hemiparesis, occurring 1-3 days after administration to patients with CNS metastases; these events associated with sudden rapid tumor enlargement Postmarketing reports of stroke or unilateral weakness [reference.medscape.com]

• Fever

  The patient was an infant who presented at the age of 10 months in an unconscious state with exsiccation, wet skin, fever, and tachycardia. [ncbi.nlm.nih.gov]

  Transient ( influenza -like symptoms, including fever (>100°F/38°C), chills/shivering, myalgia / arthralgia, fatigue/ asthenia / malaise, headache, and chills. [rxlist.com]

  If you have diabetes, see your doctor if you suspect you have athlete's foot, especially if you notice any signs of a possible secondary bacterial infection such as excessive redness, swelling, drainage or fever. [mayoclinic.org]

  […] doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever [drugs.com]

• Short Stature

  […] skin 32 HP:0000958 2 intellectual disability 32 HP:0001249 3 muscle weakness 32 HP:0001324 4 hoarse voice 32 HP:0001609 5 constipation 32 HP:0002019 6 delayed skeletal maturation 32 HP:0002750 7 short stature 32 HP:0004322 8 hypothalamic hypothyroidism [malacards.org]

  Case 1 A boy aged 10 years was referred to a paediatric endocrinology clinic following abnormal thyroid function tests performed because of fatigue and short stature. [racgp.org.au]

• Cough

  These medicines include some cough syrups as well as amiodarone, which is used to treat heart arrhythmias. Thyroid nodules are benign lumps that sometimes form on the thyroid. [healthline.com]

  Your body makes antibodies in response that protects against threats like measles, whooping cough, flu, or meningitis.Then, when you come in contact with that virus in your everyday life, your immune system is already primed to kick in so that you don [webmd.com]

  Tell your doctor about the allergy and what signs you had, like rash; hives ; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. [drugs.com]

• Dyspnea

  […] stroke or unilateral weakness occurring within 72 hr (range 20 minutes to 3 days) of administration to women without known CNS metastases Tumor enlargement that is sudden, rapid and painful reported within 12-48 hr of administration; symptoms include dyspnea [reference.medscape.com]

• Kidney Failure

  Let the person taking your blood test know of anything that might affect the readings, especially: Any serious illness such as heart attack, infection, trauma, serious liver disease or kidney failure Medication used to treat thyroid disorders, especially [btf-thyroid.org]

• Ataxia

  TRH and TRH analogs are promising clinical therapeutic agents for inducing arousal effects, amelioration of mental depression, and improvement of cerebellar ataxia. [ncbi.nlm.nih.gov]

• Difficulty Concentrating

  The symptoms of hypothyroidism include fatigue, weakness, and difficulty concentrating. [healthline.com]

  […] thyrotropin alfa had difficulty concentrating at work (9.4% vs. 22.1%, P=0.004) ( Table 3, and Table 10 in the Supplementary Appendix ). [nejm.org]

• Asthenia

  Transient ( influenza -like symptoms, including fever (>100°F/38°C), chills/shivering, myalgia / arthralgia, fatigue/ asthenia / malaise, headache, and chills. [rxlist.com]

Although she had regular menstrual cycles, had conceived spontaneously, and had good hormonal and follicular responses to gonadotropic stimulation regimens during the in vitro fertilization workup, she presented with apparent recurrent pregnancy loss [omim.org]

The authors stressed the need for a biochemical and molecular genetic workup in children with symptoms suggestive of congenital hypothyroidism, even when the neonatal TSH screening is normal. [ncbi.nlm.nih.gov]

"AACE Medical Guidelines for Clinical Practice for Evaluation and Treatment of Hyperthyroidism and Hypothyroidism" (PDF). [en.m.wikipedia.org]

There is no consensus for its treatment. We describe here a case of CPM that occurred in a young patient after correction of hyponatremia, its treatment by intravenous thyrotropin-releasing hormone, and its outcome. [ncbi.nlm.nih.gov]

Despite further enlargement of the remnant thyroid tissue on post-radioiodine scintiscanning, the patient is currently euthyroid, with normal thyroid-stimulating hormone levels; however, her long-term prognosis remains uncertain. [ncbi.nlm.nih.gov]

Prognosis The type of tinea pedis infection and underlying conditions (eg, immunosuppression, diabetes) affect the prognosis; however, with appropriate treatment, the prognosis is generally good. [emedicine.medscape.com]

Thus, life-long follow-up is required to assess the prognosis of the tumor. [doi.org]

Useful For Suggests clinical disorders or settings where the test may be helpful Recommended first-line test for detection of thyrotropin receptor (TSHR) antibodies, and used in the following situations: -Differential diagnosis of etiology of thyrotoxicosis [mayomedicallaboratories.com]

A radioimmunoassay for TSH helps the physician to distinguish the different etiologies of hypothyroidism, to confirm the diagnosis of "euthyroid" Graves' disease and to evaluate pituitary function. [ncbi.nlm.nih.gov]

Author information 1 1 Institute of Medical Epidemiology, Biostatistics and Informatics, Martin-Luther-University Halle-Wittenberg, Halle (Saale), Germany. 2 2 Department of Study of Health in Pomerania/Clinical-Epidemiological Research, Institute for [ncbi.nlm.nih.gov]

Summary Epidemiology Prevalence is unknown. [orpha.net]

A common third cause has been genetically mapped to a locus on chromosome 15, but the underlying pathophysiology has not yet been elucidated. [ncbi.nlm.nih.gov]

Register Pathophysiology of Pulsatile and Copulsatile Release of Thyroid-Stimulating Hormone, Luteinizing Hormone, Follicle-Stimulating Hormone, and α -Subunit * - 24 Hours access EUR €36.00 GBP £28.00 USD $45.00 Rental This article is also available [doi.org]

VIVO Pathophysiology Thyroid-stimulating hormone, also known as thyrotropin, is secreted from cells in the anterior pituitary called thyrotrophs, finds its receptors on epithelial cells in the thyroid gland, and stimulates that gland to synthesize and [vivo.colostate.edu]

A number of tests are required by law and all of the tests are basically problems that would result in mental retardation and are all preventable. [antranik.org]

This tissue-specific glycosylation prevents each TSH from cross activity. Interestingly, this is the first time the role of tissue-specific glycosylation in preventing functional crosstalk between signaling molecules has been shown. [medicaldaily.com]

Prevention of fetal hyperthyroidism by administration of antithyroid drug (ATD) and levothyroxine (LT(4)) to pregnant patients who previously received ablative therapy has been reported. [ncbi.nlm.nih.gov]

Please prevent freeze-thaw cycles. Amino acid sequence Pyr-His-Pro-NH 2. Purity Greater than 98.5% as determined by Analysis by RP-HPLC. Usage Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. [prospecbio.com]