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Tinea Capitis Profunda

Kerion celsi


Presentation

  • Figure 1 Weeping, pustular scalp lesion at presentation.[adc.bmj.com]
  • The most common presenting symptoms of ALL are nonspecific (e.g., bleeding, fever, lymphadenopathy, bone pain) [ 2, 3 ].[clinical-pediatrics-dermatology.imedpub.com]
  • The boy lived on a farm where cows and calves were present. He presented with a 5 cm erythematous, erosive, edematous, and sharply defined lesion with yellow crusts and circumscribed alopecia on the temporoparietal scalp.[ncbi.nlm.nih.gov]
Rhinitis
  • Experience with 6 cases]. ( 8657953 ) Zaror L...Navarrete M 1995 36 The association of perennial rhinitis with Trichophyton infection. ( 1611549 ) Kivity S...Fireman E 1992 37 Tinea of the eyebrow showing kerion celsi reaction: report of one case. ( 1657533[malacards.org]
Aspiration
Abdominal Distension
Constipation
Hepatosplenomegaly
  • Physical examination showed hepatosplenomegaly cervical lymphadenopathy in addition to the nodule. Bone marrow aspiration was performed and morphological and flow cytometric analysis was consistent with B cell ALL.[clinical-pediatrics-dermatology.imedpub.com]
Bone Pain
  • ., bleeding, fever, lymphadenopathy, bone pain) [ 2, 3 ]. Herein we report the case of a three year old girl with B cell ALL presenting with a nodule on the scalp skin, mimicking kerion celsi (tinea capitis profunda).[clinical-pediatrics-dermatology.imedpub.com]
Alopecia
  • It is characterized by one or more large, tender boggy masses with erythema, pustules, crusting, and alopecia. Such a mass is called a kerion. Lymphadenopathy is frequent.[dermis.net]
  • Abstract A 28-month-old boy developed a cutaneous and subcutaneous lesion of the scalp together with alopecia. Treatment with sulfadiazine silver ointment and oral administration of cefaclor failed.[ncbi.nlm.nih.gov]
  • […] predominantly affects the scalp and that is characterized by the development of painful crusty lesions covered with follicular pustules and surrounded by erythematous alopecic areas, that can later evolve into abscesses and leave permanent cicatricial alopecia[orpha.net]
Ulcer
  • A culture of the secretion from the ulcer in the lesion tested negative for bacteria. Mycological examination The affected hair and excretion from the ulcer were taken and prepared with a potassium hydroxide (KOH) solution for direct examination.[mmy.oxfordjournals.org]
  • They described the lesions asymtomatic papules and nodules brown- red to violence without ulceration.[clinical-pediatrics-dermatology.imedpub.com]

Treatment

  • An occasional lesion requires additional treatment to one or two small areas two weeks after the[jamanetwork.com]
  • The low dose of terbinafine was continued for 16 days until the treatment was completed. The patient was cured clinically and mycologically 72 days after initiation of treatment without adverse drug-related events.[mmy.oxfordjournals.org]
  • In the first stage of the treatment, the antibacterial agents should be topically applied in the thick layer.[aspergillus.org.uk]

Prognosis

  • LC often has rapid disease progression and poor prognosis. The mean interval between diagnosis of LC and death was reported as 3.8 and 4.8 months respectively in different studies [ 13, 14 ]. The interval time was 2 months for our patient.[clinical-pediatrics-dermatology.imedpub.com]
  • Diagnosis, treatment, and prognosis We had established that the etiologic agent was M. gypseum based on morphologic features, biochemical test results and molecular methods.[mmy.oxfordjournals.org]

Etiology

  • Moreover, the new or previously very sporadic etiologic agents causing kerion have been recently observed in Croatia, such as T. tonsurans, mostly in wrestlers, so far.[aspergillus.org.uk]
  • Topical application of naftifine-ketoconazole cream after use of ketoconazole shampoo was used to wash out and kill the etiologic agent on the surface of the hair.[mmy.oxfordjournals.org]
  • Tinea pedis, or athlete's foot, is the most common dermatophyte infection Its etiology is closely tied to the use of occlusive footwear.12 Most commonly, tinea. Synonyms for tinea profunda in Free Thesaurus.[amunisocyxekyhero.xpg.uol.com.br]

Epidemiology

  • “Updates on the epidemiology of dermatophyte infections”. Mycopathologia.. vol. 166. 2008. pp. 335-52. (Highlights the change in epidemiology of dermatophyte species over the last 100 years.[dermatologyadvisor.com]
  • Kerion celsi: a clinical epidemiological study, Mycoses, 1998 , vol. 41 (pg. 169 - 173 ) 3. Tinea capitis: no incision nor excision, J Pediatr Surg, 2007 , vol. 42 (pg. e33 - e36 ) 4.[mmy.oxfordjournals.org]
  • Kerion celsi: a clinical epidemiological study , Mycoses , 1998 , vol. 41 (pg. 169 - 173 ) 3. Tinea capitis: no incision nor excision , J Pediatr Surg , 2007 , vol. 42 (pg. e33 - e36 ) 4.[academic.oup.com]
  • Updates on the epidemiology of dermatophyte infections. Mycopathologia. 2008 Nov-Dec. 166(5-6):335-52. [Medline]. Kondo M, Nakano N, Shiraki Y, Hiruma M, Ikeda S, Sugita T.[emedicine.medscape.com]
Sex distribution
Age distribution

Pathophysiology

  • Pathophysiology Dermatophytes, which are keratinophilic fungi, are the causative agents. These are molds that live in the cornified layers of the skin and are capable of invading the outermost layer of skin, hair, and nails.[dermatologyadvisor.com]

Prevention

  • The most recent advances require corresponding evolution of diagnostic and treatment strategies of kerion in order to provide the suitable laboratory testing and antifungal therapy and to prevent the unnecessary surgical procedures. abstract No: Full[aspergillus.org.uk]
  • Combs and hairbrushes should be disinfected or discarded to prevent transmission of infection or re- infection. As the fungus causing the kerion (e.g.[dermnetnz.org]
  • Household items such as brushes and combs should be replaced and then boiled for 5 minutes once a week while the patient is on therapy to prevent reinfection. Patients should not share brushes, combs, or hats with other family members.[dermatologyadvisor.com]

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