Presentation
A marked peripheral eosinophilia is often present. If the parasitic infection is low, eosinophilia may be the only diagnostic sign evident. Occasionally, splinter hemorrhages may be present below the nails. [clinicalgate.com]
Calabar swellings are subcutaneous edematous areas of 3-10 cm that are nonerythematous and do not pit; local pain, pruritus, and mild fever may be present. [antiinfectivedrugs.com]
The most common presenting feature is abdominal pain, observed in 98% of patients. Less common features include ascending cholangitis, acute pancreatitis, and, rarely, obstructive jaundice. [emedicine.medscape.com]
FIELD EVALUATION It is critical to know the nematode species present and the density of their populations to make management decisions. [ipm.ucanr.edu]
The vector is present in the United States but there is no presence of Bursaphelenchus cocophilus yet. Native Origin Native Origin: Central and South America Current Location U.S. [tsusinvasives.org]
Entire Body System
- Anemia
Hookworms The major manifestations of hookworm disease include iron deficiency anemia and chronic protein energy malnutrition. [emedicine.medscape.com]
Heavy infections can result in enough blood loss to result in anemia. Finding the hookworm egg in a fecal examination is the basis of lab diagnosis. [livestrong.com]
[…] damage, ocular damage (visual impairment and blindness), and brain damage (seizures and coma) Granuloma formation causes damage Fecal-oral Ingestion of eggs Migrates from intestinal wall to blood Bendazoles Trichuris trichiura (whipworm) Microcytic anemia [medbullets.com]
Clonorchis sinensis Clonorchiasis Lever fluke Inflammation of biliary tract Praziquontel 17 Paragonimus westermani Paragonimiasis Lung fluke Infection of lung Praziquontel 18 Ancylostoma duodenale Hookworm Intestinal nematodes Intestinal infection and cause anemia [medimoon.com]
Eyes
- Visual Impairment
impairment and blindness), and brain damage (seizures and coma) Granuloma formation causes damage Fecal-oral Ingestion of eggs Migrates from intestinal wall to blood Bendazoles Trichuris trichiura (whipworm) Microcytic anemia Abdominal pain and diarrhea [medbullets.com]
Prevalence and Incidence Onchocerciasis is the second leading cause of blindness due to infection in the world. [2] It is estimated that anywhere between 18 - 37 million people are infected, with up to 1-2 million people who are visually impaired and [eyewiki.aao.org]
- Visual Impairment
impairment and blindness), and brain damage (seizures and coma) Granuloma formation causes damage Fecal-oral Ingestion of eggs Migrates from intestinal wall to blood Bendazoles Trichuris trichiura (whipworm) Microcytic anemia Abdominal pain and diarrhea [medbullets.com]
Prevalence and Incidence Onchocerciasis is the second leading cause of blindness due to infection in the world. [2] It is estimated that anywhere between 18 - 37 million people are infected, with up to 1-2 million people who are visually impaired and [eyewiki.aao.org]
- Photophobia
These symptoms can be very severe, leading to excoriation, bleeding, and even suicide. [1] [17] In terms of ocular disease, patients will classically complain of an insidious onset of decreased vision, eye redness, eye pain and photophobia related to [eyewiki.aao.org]
Workup
Microbiology
- Necator Americanus
Hookworm, Ancylostoma duodenale, and Necator americanus. Juveniles in the soil can burrow into human skin. The eggs are usually eaten along with food. However, it appears that hookworm infections in humans are not always totally bad news! [bumblebee.org]
Types of Roundworms There are a number of different species of roundworms but the most common ones to infect humans include: Ascaris lumbricoides (most common roundworm infections in humans) Hookworms ( Ancylostoma duodenale and Necator americanus ) Guinea [healthhype.com]
Treatment
Treatment The treatment of choice is ivermectin, 150 5g/kg orally as a single dose, which kills microfilariae but is less effective against adult worms. Treatment is repeated at 3-mo intervals for 2-3 years. [antiinfectivedrugs.com]
Treatment is usually with thiabendazole or albendazole. Enterobiasis Enterobius vermicularis (the threadworm) is cosmopolitan. [oxfordmedicine.com]
Treatment If asymptomatic then no treatment is required. Otherwise, either diethylcarbamazine or ivermectin is effective. [patient.info]
Treatment: diethylcarbamazine (DEC) or ivermectin, surgical remonval. 28 NON-FILARIAL TISSUE NEMATODE INFECTIONS treatment Diagnosis Location in human Mode of transmission Disease Nematode species Surgical extraction clinical Subcutaneous, mainly in lower [slideplayer.com]
Long-term suppression of Mansonella streptocerca microfilariae after treatment with ivermectin. J Infect Dis 180 : 1403 – 1405. 70. Gonzalez AA ,, Chadee DD ,, Rawlins SC. 1999. Ivermectin treatment of mansonellosis in Trinidad. [asmscience.org]
Prognosis
Describe trichinosis and disease progression in humans, including body sites affected, peripheral blood presentation, severity of disease, and prognosis. 5. List the various methods used to diagnose tissue nematode infections. 6. [clinicalgate.com]
Prognosis Prognosis depends on the stage at which the infection is treated. If treated early during the course of the disease, the corneal opacities may be minimal and may recede with appropriate treatment. [eyewiki.aao.org]
Etiology
Surgery Surgical interventions can be directed at the underlying etiology of vision loss. Cataract extraction can be performed on visually significant cataracts induced by the disease process. [eyewiki.aao.org]
Epidemiology
Epidemiology It is estimated that 2-13 million humans are infected with the Loa loa larvae. [patient.info]
Epidemiology Trichinella occurs worldwide with the cycle maintained in several different mammalian species. The mammal serves as the definitive host for the adult worm and the intermediate host for the encysted larvae. [clinicalgate.com]
Human filariasis: a global survey of epidemiology and control. University Park Press, Baltimore, MD. 8. Freedman DO ,, de Almeida Filho PJ ,, Besh S ,, Maia e Silva MC ,, Braga C ,, Maciel A. 1994. [asmscience.org]
Onchocerca volvulus DNA probe classification correlates with epidemiologic patterns of blindness. J Infect Dis 165, 964-8 (1992). ↑ Erttmann, K.D., Meredith, S.E., Greene, B.M. & Unnasch, T.R. [eyewiki.aao.org]
Systematics and epidemiology of trichinella. Adv Parasitol. 2006. 63:367-439. [Medline]. Pozio E, Gomez Morales MA, Dupouy-Camet J. Clinical aspects, diagnosis and treatment of trichinellosis. Expert Rev Anti Infect Ther. 2003 Oct. 1(3):471-82. [emedicine.medscape.com]
Pathophysiology
Pathophysiology The multiple sequelae result from direct invasion of the nematodes, which leads to induction of inflammation in the infected host. [eyewiki.aao.org]
Prevention
Prevention Control of blackfly by spraying. Mass distribution of ivermectin. [patient.info]
Care should be taken to practice preventative measures before the nematode population increases and infests the entire field. [blog.agrivi.com]
As will be explained further, eradication of the disease is relatively simple and is in near sight--eradication can be accomplished simply by preventing people from drinking from water contaminated by the parasite. [web.stanford.edu]
Prevention (Sanitation and Exclusion) Use certified clean, nematode-free seed. Stem nematode is not seedborne, but can live on alfalfa chaff. [ipm.ucanr.edu]
However, the focus should also be on prevention to avoid a recurrence of the infection. The worms do not have to be removed surgically unless large number of worms are causing an obstruction, or other complications. [healthhype.com]