Clinical and immunohistochemical features of this rare case are presented and discussed. [ncbi.nlm.nih.gov]

The current case shows the value of multiple biopsy sites when the presentation is heterogeneous in appearance, as well as the importance of a high index of suspicion for carcinoma. [nejm.org]

• Fatigue

  This is where complementary medications help in getting rid of fatigue. [epainassist.com]

  Weight loss and fatigue are not uncommon. Treatment may lead to pain, xerostomia, infections, poor wound healing, dysphagia, fistula formation, trismus, potential disfigurement and fatigue. [patient.info]

  Radiotherapy has side effects like: sore skin ulcers in the mouth fatigue dry mouth loss of, or changes in, taste loss of appetite nausea bad breath etc. [news-medical.net]

• Constitutional Symptom

  CASE DESCRIPTION In December 2005, a 66-year-old woman presented to the otolaryngology clinic at our institution with mild dysphagia and a globus sensation, with no constitutional symptoms, odynophagia, or referred otalgia. [current-oncology.com]

• Respiratory Insufficiency

  There was no finding suggestive of local recurrence; however, the patient died from hemoptysis and respiratory insufficiency. [ncbi.nlm.nih.gov]

• Lesion of the Tongue

  Drainage patterns depend on the location of the primary lesion 6 : anterior tongue: level Ia nodes (submental nodes) lateral tongue level Ib nodes : submandibular and level II nodes : upper jugulodigastric nodes potentially drain directly to level IV [radiopaedia.org]

  In general, low-grade lesions of the tongue base tend to be well demarcated, enhance uniformly, and demonstrate T1 hypointensity and T2 hyperintensity. High-grade lesions tend to have less distinct and infiltrative margins. [ajnr.org]

  CASE REPORT A 12-year-old male Caucasian patient was referred by the Hematology Service to the Stomatology and Bucomaxillofacial Cancer Prevention Service of São Lucas Hospital, (Brazil) for examination of asymptomatic white lesions on his tongue with [scielo.br]

  With early stage carcinoma of the oral tongue, partial glossectomy is adequate treatment in most cases. 9 Martin and coworkers do not favor neck dissection for occult metastatic lesions from the tongue however prophylactic dissection, used on an individua1 [journalgateway.com]

• Photosensitivity

  METHODS: In this study we prepared covalent conjugates between the photosensitizer chlorin(e6) and hyperbranched poly(ether-ester), HPEE. [ncbi.nlm.nih.gov]

• Otalgia

   Referred otalgia results from innervation by V3,lesser palatine nerve, and the glossopharyngeal nerve.  Lymphatic into Level II nodes. 10. Floor of the Mouth 11. Tongue 12. [slideshare.net]

  Symptoms of tongue base tumors may be odynophagia (pain on swallowing food or fluid), otalgia (pain in the ear), or a mass in the neck. The mass is usually due to metastases that can be felt in three-quarters of cases at the time of the diagnosis. [medicinenet.com]

  CASE DESCRIPTION In December 2005, a 66-year-old woman presented to the otolaryngology clinic at our institution with mild dysphagia and a globus sensation, with no constitutional symptoms, odynophagia, or referred otalgia. [current-oncology.com]

• Referred Otalgia

   Referred otalgia results from innervation by V3,lesser palatine nerve, and the glossopharyngeal nerve.  Lymphatic into Level II nodes. 10. Floor of the Mouth 11. Tongue 12. [slideshare.net]

  CASE DESCRIPTION In December 2005, a 66-year-old woman presented to the otolaryngology clinic at our institution with mild dysphagia and a globus sensation, with no constitutional symptoms, odynophagia, or referred otalgia. [current-oncology.com]

  The evaluation of a patient with tongue cancer begins with a detailed history, specifically inquiring about tobacco and alcohol use, pain, weight loss, dysphagia and odynophagia, referred otalgia, hemoptysis, neck mass, hoarseness, and articulation difficulties [emedicine.medscape.com]

• Neck Mass

  A neck mass may, therefore, be the presenting complaint. A common staging system is used for all squamous cell carcinomas of the oral cavity, with tumor staging being based on size and extension into adjacent structures. [radiopaedia.org]

  Other symptoms include: A sore on the lip that doesn't heal Persistent lip pain or lip numbness A lump or thickening on the lip A white or red patch on the lip A neck mass Treatments for lip cancer Our goal is to treat lip cancer in ways that cause as [cancercenter.com]

• Headache

  The side effects of this treatment can include: fever headache vomiting diarrhea an allergic reaction skin rashes Although these treatments do have side effects, they’re often necessary in beating the cancer. [healthline.com]

  Tianna Age 17 Stage IV Nasopharyngeal Cancer Non Smoker TIANNA from Illinois Symptoms: Persistent headache and sore throat Treatment: Modified neck dissection, radiation and chemotherapy Delay in Diagnosis: 6 weeks I had a headache and a sore throat that [sixstepscreening.org]

• Cavitary Lesion

  There was a big cavitary lesion in the right lower lobe and bilateral multiple nodular lesions, some of which had cavity formation on computed tomography. [ncbi.nlm.nih.gov]

Curative treatment for base-of-tongue squamous cell carcinoma (BOT SCC) has evolved over time; however, comparative outcomes analysis for various treatment strategies is lacking. [ncbi.nlm.nih.gov]

CONCLUSIONS: Bcl-2 is associated with aggressive disease, neck lymph node metastasis, and poor prognosis. Whereas Bax is related with histologic grade. [ncbi.nlm.nih.gov]

If metastasis (such as to the local lymph nodes) is observed, then the prognosis is guarded or unpredictable Tumors in their early stage with complete excisional treatment typically have good prognosis In cases of metastasis, its prognosis depends upon [dovemed.com]

The etiology of the lesion was considered to be ischemia secondary to compression by the necrotic myocutaneous flap. [ncbi.nlm.nih.gov]

Etiology 19. Etiology 20. [slideshare.net]

This report focuses on the etiological factors and prognosis related to the case. Additionally, a brief literature review regarding squamous cell carcinoma in young patients is also included. [indianjcancer.com]

This study emphasizes the current clinico-epidemiological trends of carcinoma tongue in central India and needs more studies on this issue to tackle the situation efficiently. [ccij-online.org]

Key variants in OTSCC and their relationship with habits, clinical and epidemiological parameters. A. [f1000research.com]

Further research in molecular profiling and epidemiology is essential to elucidate the causal factors of OTSCC in young adults. [jco.ascopubs.org]

Epidemiology and risk factors are similar to squamous cell carcinomas elsewhere in the upper aerodigestive tract, with tobacco smoking and alcohol ingestion being major risk factors 1-3,9. [radiopaedia.org]

The fact that expression of the immune-related proteins varied between HPV-positive and HPV-negative cases was considered to be linked to the stronger immune defense activity found in cases of HPV-positive TSCC/BOTSCC. [3] Pathophysiology The tongue is [emedicine.medscape.com]

The 5-year survival rate for patients with localized disease at diagnosis is 83%, compared with 32% for those whose cancer has spread. 1-3 Pathophysiology Oral cancer can develop in any part of the mouth, including the lips, gums, tongue, cheeks, and [uspharmacist.com]

A few methods to prevent Squamous Cell Carcinoma of Tongue include: Maintain proper oral hygiene Avoid chewing tobacco and smoking Regular medical screening at periodic intervals with blood tests, scans, and physical examinations, are mandatory, due to [dovemed.com]

The role of the dental practitioner in detection and prevention of oral cancer: review of the literature. Dent Update. 2000;27:404-08. Yoleri L, Mavioglu H. [rarediseases.org]

Asian Pacific Journal of Cancer Prevention. Asian Pacific Organization for Cancer Prevention. 14 (10): 5567–5577. doi : 10.7314/apjcp.2013.14.10.5567. ISSN 1513-7368. [en.wikipedia.org]

The main aims of treatment are tumor eradication, recurrence prevention and conservation and/or restoration of form and function of the tongue. [ccij-online.org]