The main outcome measures included cessation of the presenting tonic-clonic convulsion/episode of convulsive status epilepticus; the number of additional drugs required to stop the convulsion; people demonstrating respiratory depression and people requiring [ncbi.nlm.nih.gov]

Approximately 22 other posters about research on perampanel's safety profile and effectiveness were also presented at the meeting. [eisai.mediaroom.com]

This four step guideline is presented in this paper. [adc.bmj.com]

Witnesses present during the episodes often report them as "seizures." The spared consciousness and variability may be evidence against an epileptogenic mechanism. [jamanetwork.com]

They are characterized by non-motor symptoms, although brief twitches may be present. A common symptom of this type of seizure is blank staring that is often mistaken for daydreaming. [dravetsyndromenews.com]

Children experiencing this type of seizure may not require an extensive workup. The same may apply to children with a known seizure disorder who are already on anticonvulsant therapy. [cps.ca]

First-line treatment First-line treatment usually begins outside the hospital. It has been shown that prehospital treatment of children reduces seizure length but often is not utilized [11]. [cps.ca]

Treatment for non-convulsive status epilepticus is less urgent than for convulsive status epilepticus. [nice.org.uk]

"Experiencing freedom from seizures, especially convulsive seizures, is a key objective in the treatment of epilepsy, and there is growing interest among doctors in the safety and efficacy of monotherapy AED treatment options like perampanel," said Lynn [eisai.mediaroom.com]

Emergency medical services (paramedics) also carry medicine so they can start treatment as soon as they arrive. [epilepsy.org.uk]

There may be variations in treatment that your pediatrician may recommend based on individual facts and circumstances. [healthychildren.org]

What Is the Prognosis for Seizures in Children? The prognosis for children with seizures depends on the type of seizures. Most children do well, are able to attend regular school, and have no limitations. [emedicinehealth.com]

An investigator must consider whether to include patients with a narrow spectrum of seizure etiologies (e.g. febrile seizures) as opposed to including ‘all-comers’. Additionally, efficacy and adverse event outcomes are not well standardized. [academiccommons.columbia.edu]

Common etiologies are listed in Table 1 [3]. Mortality has been reported to be between 2.7% and 8%, with an overall morbidity (mainly newly diagnosed neurological disorders) of between 10% and 20% [2]. [cps.ca]

With PGES Without PGES Number of patients 109 64 45 Age (year) 35 (12.3) 35 (14.7) 35 (10.9) Gender F (56%), M (44%) F (57%), M (43%) F (54%), M (46%) Seizure onset (year) 11 ± 8.3 12 ± 8.1 10 ± 9.4 Duration of epilepsy 21 ± 10.7 20 ± 12.1 22 ± 10.3 Etiologies [onlinelibrary.wiley.com]

If signs or symptoms are present, immediately evaluate the patient and discontinue FYCOMPA if an alternative etiology for signs or symptoms cannot be established. [eisai.mediaroom.com]

Descriptive epidemiology of epilepsy: Contributions of population-based studies from Rochester, Minnesota. Mayo Clinic Proceedings, 71(6). 576-586. [epilepsyaustralia.net]

Data from epidemiological studies suggest that four to eight children per 1000 may be expected to experience an episode of CSE before the age of 15 years, 8 and in children with first seizures, 12% present with CSE as their first unprovoked seizure. 9 [adc.bmj.com]

Key Words: Convulsions; Emergency management; Paediatrics; Seizures; Status epilepticus Background and epidemiology The conventional definition of convulsive status epilepticus (CSE) is continuous generalized tonic-clonic seizure activity with loss of [cps.ca]

The pathophysiological mechanisms remain uncertain. Further functional studies are necessary to clarify the nature of this phenomenon. Accepted for publication July 5, 2000. We thank Jose A. Bueri, MD, for his kind collaboration. [jamanetwork.com]

How to Prevent Seizures in Children Most seizures cannot be prevented. There are some exceptions, but these are very difficult to control, such as head trauma and infections during pregnancy. [emedicinehealth.com]

Termination of the seizure and prevention of recurrence Principles of treatment and monitoring The major goal of treatment is to stop the seizure and, in doing so, prevent brain injury. [cps.ca]

Simple preventative measures can be taken to decrease seizures triggered this way such as wearing wrap-around sunglasses to reduce glare and covering one eye to reduce the effects of flickering or flashing light. [epilepsyaustralia.net]

However, these approaches do not prevent future febrile seizures, but only make the child more comfortable. If a bacterial infection is present, your doctor will probably prescribe an antibiotic. [healthychildren.org]

However, the guideline stated that 'for practical purposes, the approach to the child who presents with a tonic–clonic convulsion lasting more than 5 minutes should be the same as the child who is in "established" status – to stop the seizure and to prevent [nice.org.uk]