Manganese poisoning presents clinically with parkinsonian-like symptoms and psychological changes. Seizures are a rare presentation of this disease. [ncbi.nlm.nih.gov]

• Massive Splenomegaly

  We present a unique case of massive splenomegaly, hepatomegaly, and lymphadenopathy caused by lipid-laden macrophages in a 50 year old white female with short-bowel syndrome treated with long-term total parenteral nutrition. [ncbi.nlm.nih.gov]

• Noncompliance

  Noncompliance and an inability to discontinue TPN earlier increase the likelihood of complications. Discontinuation of parenteral support requires an assessment of gastrointestinal anatomy and absorption capacity. [ncbi.nlm.nih.gov]

• Lymphadenopathy

  We present a unique case of massive splenomegaly, hepatomegaly, and lymphadenopathy caused by lipid-laden macrophages in a 50 year old white female with short-bowel syndrome treated with long-term total parenteral nutrition. [ncbi.nlm.nih.gov]

• Persistent Vomiting

  She was admitted to the hospital for persistent vomiting. In the hospital, she continued to receive TPN without MVI, but continued taking an oral multivitamin preparation. [ncbi.nlm.nih.gov]

After this treatment, nine of the 25 patients were readmitted for recurrence of appetite loss. Two patients required additional TPN treatment, but seven immediately recovered their appetite after hospitalization without TPN treatment. [ncbi.nlm.nih.gov]

(PCI) was not associated with survival, low CA-125 within one week of GT placement was associated with improved survival (p CONCLUSIONS: Women with malignant bowel obstructions from gynecologic cancers requiring palliative GT placement had a guarded prognosis [ncbi.nlm.nih.gov]

This case illustrates the difficulty in establishing etiology in some patients and the effectiveness of total parenteral nutrition plus octreotide therapy in idiopathic chylous ascites in HIV-infected patients. [ncbi.nlm.nih.gov]

Additional case reports should be directed to the Epidemiology Branch, Division of Epidemiology and Surveillance, Office of Epidemiology, Center for Drug Evaluation and Research, Food and Drug Administration, Room 15-42, 5600 Fishers Lane, Rock- ville [cdc.gov]

The pathophysiology is postulated to be multifactorial. Diagnosis in adults is primarily by exclusion, eliminating other causes of chronic liver disease or cirrhosis, and other factors seen in critically ill or postoperative patients on TPN. [ncbi.nlm.nih.gov]

[…] and intervene as appropriate (e.g., hyperglycemia, fluid imbalance, infection) Educate client on the need for and use of TPN Apply knowledge of nursing procedures and psychomotor skills when caring for a client receiving TPN Apply knowledge of client pathophysiology [registerednursing.org]

"The pathophysiology of prolonged periods of no enteral nutrition or nothing by mouth". Newborn & Infant Nursing Reviews. 3 (2): 47–54. doi : 10.1016/S1527-3369(03)00005-9. [en.wikipedia.org]

This complication can be prevented by monitoring the client and adjusting the rate of the total parenteral nutrition to prevent fluid overload. [registerednursing.org]

An awareness of the factors that influence crystal solubility may prevent adverse interactions in patients who require parenteral nutrition. [ncbi.nlm.nih.gov]

Hand hygiene prevents the spread of microorganisms. Proper identification prevents patient errors. Compare MAR to patient wristband 4. Complete all safety checks for CVC as per agency policy. [opentextbc.ca]