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Toxic Effect of Copper Salts


Presentation

  • Petroleum does contain many acutely toxic, chronically toxic, and carcinogenic compounds such as benzene, however, and we must assume that some of them are present in copper naphthenate.[beyondpesticides.org]
  • Data present means standard error based on 3 replicates with 10 fish each.[fisheriessciences.com]
  • Zinc chloride is corrosive and should not be used when copper fixtures are present. This product is toxic to fishes and aquatic invertebrates. Avoid contaminating water sources with zinc chloride.[bryophytes.science.oregonstate.edu]
  • Workshop Proceedings: Copper BLM Workshop Presentations: Copper BLM Top of Page[epa.gov]
  • All information presented is for general reference and does not represent a professional opinion nor the policy of an author's employer.[finishing.com]
Anemia
  • Hemolytic anemia and anuria can result and may be fatal. Indian childhood cirrhosis, non-Indian childhood cirrhosis, and idiopathic copper toxicity are probably identical disorders in which excess copper causes cirrhosis.[merckmanuals.com]
  • Complications If as little as 2gm of a copper salt are ingested, usually with suicidal intent, the resulting copper-induced hemolytic anemia and kidney damage are generally fatal.[diagnose-me.com]
  • According to eMedicine, symptoms of lead toxicity include headaches, low appetite, irritability, digestive problems, lethargy, insomnia, hypertension and iron deficiency anemia.[leaf.tv]
  • Chronic health effects Chronic exposure to copper salts may result in anemia.11 Exposure to naphthenic acids increases the permeability of membranes, which could increase uptake of other toxic substances.12 Although as much as 25% of copper naphthenate[beyondpesticides.org]
  • […] neuropathy, coma, autonomic instability, MODS Late: Alopecia, Mees lines, residual neurologic symptoms Alopecia, neuropathy Toxic: 3 µg/L (blood) MDAC Prussian blue Zinc MFF (oxide fumes); vomiting, diarrhea, abdominal pain (ingestion) Copper deficiency: anemia[emedicine.medscape.com]
Weakness
  • The results obtained with copper nitrate showed that it exerts a weak effect on the control of cercariae. The LC50 for copper sulphate, copper acetate and copper chloride was 1.25, 1.05 and 0.6 mg/1/hour respectively.[agris.fao.org]
  • According to the MedlinePlus website, symptoms of copper toxicity include nausea, vomiting, digestive discomfort, metallic taste, yellow skin and eyes, depression, anorexia and muscle weakness.[leaf.tv]
Anorexia
  • According to the MedlinePlus website, symptoms of copper toxicity include nausea, vomiting, digestive discomfort, metallic taste, yellow skin and eyes, depression, anorexia and muscle weakness.[leaf.tv]
Epilepsy
  • It is being used in radiology for the treatment of cancer, and for epilepsy. Research also suggests its anti-ulcer use.[xbrain.co.uk]
Nausea
  • In prolonged contact with copper cooking utensils, an acidic food or beverage can dissolve milligram quantities of copper, sufficient to cause acute toxicity symptoms such as self-limited nausea, vomiting and diarrhea.[diagnose-me.com]
  • According to the MedlinePlus website, symptoms of copper toxicity include nausea, vomiting, digestive discomfort, metallic taste, yellow skin and eyes, depression, anorexia and muscle weakness.[leaf.tv]
  • Typical Presentation of the Most Commonly Encountered Metals and Their Treatment (Open Table in a new window) Metal Acute Chronic Toxic Concentration Treatment Arsenic Nausea, vomiting, "rice-water" diarrhea, encephalopathy, MODS, LoQTS, painful neuropathy[emedicine.medscape.com]
  • The symptoms of copper toxicity include nausea, vomiting and abdominal and muscle pain. Excessive body copper is usually removed with the use of specific chelating agents or by the consumption of high levels of zinc.[xbrain.co.uk]
  • If you ingest copper orally, it may cause: Nausea Vomiting Diarrhea Liver Damage Kidney Damage Death While the Environmental Protection Agency (EPA) has not yet classified copper as a carcinogen to humans, questions remain regarding its safety and long[globalhealingcenter.com]
Vomiting
  • , diarrhea, painful neuropathy, coma, autonomic instability, MODS Late: Alopecia, Mees lines, residual neurologic symptoms Alopecia, neuropathy Toxic: 3 µg/L (blood) MDAC Prussian blue Zinc MFF (oxide fumes); vomiting, diarrhea, abdominal pain (ingestion[emedicine.medscape.com]
  • The symptoms of copper toxicity include nausea, vomiting and abdominal and muscle pain. Excessive body copper is usually removed with the use of specific chelating agents or by the consumption of high levels of zinc.[xbrain.co.uk]
  • Self-limited gastroenteritis with nausea, vomiting, and diarrhea may occur.[merckmanuals.com]
  • In prolonged contact with copper cooking utensils, an acidic food or beverage can dissolve milligram quantities of copper, sufficient to cause acute toxicity symptoms such as self-limited nausea, vomiting and diarrhea.[diagnose-me.com]
  • According to the MedlinePlus website, symptoms of copper toxicity include nausea, vomiting, digestive discomfort, metallic taste, yellow skin and eyes, depression, anorexia and muscle weakness.[leaf.tv]
Diarrhea
  • Self-limited gastroenteritis with nausea, vomiting, and diarrhea may occur.[merckmanuals.com]
  • , painful neuropathy, coma, autonomic instability, MODS Late: Alopecia, Mees lines, residual neurologic symptoms Alopecia, neuropathy Toxic: 3 µg/L (blood) MDAC Prussian blue Zinc MFF (oxide fumes); vomiting, diarrhea, abdominal pain (ingestion) Copper[emedicine.medscape.com]
  • In prolonged contact with copper cooking utensils, an acidic food or beverage can dissolve milligram quantities of copper, sufficient to cause acute toxicity symptoms such as self-limited nausea, vomiting and diarrhea.[diagnose-me.com]
  • If you ingest copper orally, it may cause: Nausea Vomiting Diarrhea Liver Damage Kidney Damage Death While the Environmental Protection Agency (EPA) has not yet classified copper as a carcinogen to humans, questions remain regarding its safety and long[globalhealingcenter.com]
  • Exposure to high concentrations of copper salts can cause nausea, vomiting, gastric pain and diarrhea. If it gets in the eyes it can case severe irritation and corneal clouding.[finishing.com]
Abdominal Pain
  • pain (ingestion) Copper deficiency: anemia, neurologic degeneration, osteoporosis Normal range: 0.6-1.1 mg/L (plasma) 10-14 mg/L (red cells) * *No accepted chelation regimen; contact a medical toxicologist regarding treatment plan.[emedicine.medscape.com]
Metallic Taste
  • According to the MedlinePlus website, symptoms of copper toxicity include nausea, vomiting, digestive discomfort, metallic taste, yellow skin and eyes, depression, anorexia and muscle weakness.[leaf.tv]
  • MFF, or "brass founder’s ague," "zinc shakes," or "Monday morning fever" as it is variously known, is characterized by fever, headache, fatigue, dyspnea, cough, and a metallic taste occurring within 3-10 hours after exposure.[emedicine.medscape.com]
Hypotension
  • […] nickel carbonyl: myocarditis, ALI, encephalopathy Occupational (inhaled): pulmonary fibrosis, reduced sperm count, nasopharyngeal tumors Excessive exposure: 8 µg/L (blood) Severe poisoning: 500 µg/L (8-h urine) * Selenium Caustic burns, pneumonitis, hypotension[emedicine.medscape.com]
Hypertension
  • According to eMedicine, symptoms of lead toxicity include headaches, low appetite, irritability, digestive problems, lethargy, insomnia, hypertension and iron deficiency anemia.[leaf.tv]
Jaundice
  • Jaundice and pain over the liver have been reported in acute human poisonings. Copper is mainly absorbed through the gastrointestinal tract. All other intakes of copper (inhalation and dermal) are insignificant in comparison to the oral route.[espimetals.com]
Flushing
  • Symptoms of Exposure : May cause chills, flushing, fatigue, muscle and stomach aches, dyspnea, and nausea if fumes are inhaled. Dusts may irritate skin and eyes.[espimetals.com]
Muscle Weakness
  • According to the MedlinePlus website, symptoms of copper toxicity include nausea, vomiting, digestive discomfort, metallic taste, yellow skin and eyes, depression, anorexia and muscle weakness.[leaf.tv]
Irritability
  • Skin Irritation When wearing a copper bracelet, it is common to experience mild to moderate skin irritation as well as skin discoloration.[leaf.tv]
  • Seek medical attention if irritation develops or persists. EYES : Flush eyes with lukewarm water, including under upper and lower eyelids, for at least 15 minutes. Seek medical attention if irritation develops or persists.[espimetals.com]
  • If it gets in the eyes it can case severe irritation and corneal clouding. Copper sulphate has an LD50 of 300 mg/kg for rats, so it is not particularly toxic.[finishing.com]
  • Organ damage Both copper salts and naphthenic acids are skin irritants.[beyondpesticides.org]
  • For instance, simply breathing in copper can cause irritation to your nose and throat.[globalhealingcenter.com]
Seizure
  • Normal excretion: 25 µg/24 h (urine) BAL D-Penicillamine Succimer Iron Vomiting, GI hemorrhage, cardiac depression, metabolic acidosis Hepatic cirrhosis Nontoxic: 300 µg/dL Severe: 500 µg/dL Deferoxamine Lead Nausea, vomiting, encephalopathy (headache, seizures[emedicine.medscape.com]

Treatment

  • Despite early treatment, many children have abnormal neurodevelopment.[merckmanuals.com]
  • It is used for the purification of water and treatment of chest infection. Some research show that copper can help prevent arthritis and other join related inflammations. It is being used in radiology for the treatment of cancer, and for epilepsy.[xbrain.co.uk]
  • Typical Presentation of the Most Commonly Encountered Metals and Their Treatment (Open Table in a new window) Metal Acute Chronic Toxic Concentration Treatment Arsenic Nausea, vomiting, "rice-water" diarrhea, encephalopathy, MODS, LoQTS, painful neuropathy[emedicine.medscape.com]
  • Like her, women who cannot find a scientific solution end up considering theories on nutrition and alternative treatments as a possible remedy to their psychological and physical distress.[womensenews.org]
  • Mollusks accumulate more naphthenic acids than less toxic components of oil.16 Leaching potential and environmental fate Copper salts have been found to leach from wood treatment sites.[beyondpesticides.org]

Prognosis

  • Because early diagnosis and treatment seem to result in a better prognosis, the disorder is ideally detected before age 2 wk. However, diagnostic accuracy of these tests is limited. Thus, other tests are being developed.[merckmanuals.com]
  • […] toxicity, though sharing some similarities with Wilson's Disease , is different in that the latter is an inherited & rare genetic disorder which, like copper toxicity, causes copper to collect in the liver, brain and other body tissues, but has a more dire prognosis[coppertoxic.com]

Etiology

  • […] and multiple body system manifestations due to the underlying etiology.[icd10data.com]

Prevention

  • Copper sulfate prevents these problems. Test soil regularly, and apply copper sulfate as needed in a spray or fertilizer preparation.[homeguides.sfgate.com]
  • Most diets contain enough copper (2-5mg daily) to prevent a deficiency and not enough to cause toxicity. The World Health Organization (WHO) suggests that 10-12mg per day may be the upper safe limit for consumption. Diagnose your symptoms now![diagnose-me.com]
  • The rates for application should be followed closely to prevent toxicity. Generally, the rates of copper are about 3 to 6 pounds per acre, but this is really dependent on the soil type and plants grown.[gardeningknowhow.com]
  • Some research show that copper can help prevent arthritis and other join related inflammations. It is being used in radiology for the treatment of cancer, and for epilepsy. Research also suggests its anti-ulcer use.[xbrain.co.uk]
  • Many lakes and streams are treated with copper to help prevent overgrowth of algae. If you live near a copper smelting plant, there is a good chance your soil has a large amount of copper in it.[globalhealingcenter.com]

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