The main results obtained are (i) only triglycerides and aniline are required to produce PAP esters, thus eliminating the possibility that unknown activators present in the deodorization tank were required for toxification of the oil; (ii) PAP and PAP [ncbi.nlm.nih.gov]

• Memory Impairment

  Cognitive symptoms - impaired memory, impaired concentration, or mood change. Gastrointestinal symptoms are less common - these include dry mouth, dyspepsia, dysphagia and diarrhoea. [patient.info]

• Difficulty Concentrating

  concentrating and difficulty communicating. [rarediseases.org]

• Tingling

  Further, other symptoms included joint pains, weakness or fatigue, difficulty breathing or cough, rash, headache, peripheral edema (swelling), fever and abnormal tingling sensations. [rarediseases.org]

Research into the etiologic agents, preferred treatments, and ways to avoid similar problems in the future is needed. [ncbi.nlm.nih.gov]

TOS was the leading cause of death among subjects CONCLUSIONS: The major clinical manifestations showed worse prognosis for overall and TOS-related mortality. [ncbi.nlm.nih.gov]

Prognosis In most patients, there was slow improvement after stopping their use of L-TRP products; most patients reported improvement two years after onset of EMS. [patient.info]

When PHT becomes observable it is already advanced; 15 ,16 and d) PHT is a severe condition and therapeutic interventions modify the prognosis. 15 ,16 Given these circumstances, and the fact that patients with TOS are affected by a new syndrome whose [revespcardiol.org]

This finding is the first reported chemical link between TOS and EMS and suggests that these two related diseases share a common etiology, namely, PAA. [ncbi.nlm.nih.gov]

An analysis of the epidemiological evidence available on TOS is carried out in this paper, in an attempt to elucidate the aetiological role of the purported toxic oil. [ncbi.nlm.nih.gov]

The pathophysiology is not well understood. [patient.info]

The exact pathophysiology of EMS remains unknown. [emedicine.medscape.com]

Clinical features in 20 patients and aspects of pathophysiology. Ann Intern Med. 1990;113:124-134. http://www.ncbi.nlm.nih.gov/pubmed/2360751 Hertzman PA, Blevins WL, Mayer J, et al. [rarediseases.org]

Clearly, developing an understanding of causative agents will be essential for the development of strategies for therapy, if not prevention, of these health problems. [ncbi.nlm.nih.gov]

As this did not entirely prevent the possibility of the commission reaching inconvenient conclusions, it was soon closed down altogether. [guardian.co.uk]

In the uncertainty prevailing at the time, these investigations - which some epidemiologists might consider crude - were carried out with a zeal and commitment reminiscent of John Snow’s search for clues to prevent the spread of cholera in London in the [helid.digicollection.org]