Presentation
Moreover, the 58 and 68-kDa antigens presented the lowest IgM cross-reactivity. When tested as a combination, a mixture of the 58 and 68-kDa antigens presented 100% sensitivity and specificity, as well as minor cross-reactivity. [ncbi.nlm.nih.gov]
In the present study, parasitic ova contaminated the soil and/or floor present in the kennel and it might be reason for development of the chronic and recurrent gastritis in dogs. [alliedacademies.org]
Entire Body System
- Veterinarian
If your dog is showing symptoms of having roundworms or if you visually see “spaghetti type” worms in his vomit or stool, he should be seen by a veterinarian as soon as possible. [wagwalking.com]
Due to its zoonotic potential, this roundworm is of special interest not only for veterinarians, but also for medical practitioners. [ncbi.nlm.nih.gov]
Take your pets to the veterinarian to prevent infection with Toxocara. Your veterinarian can recommend a testing and treatment plan for deworming. [cdc.gov]
I’m sitting in my usual study spot, at my favorite cafe, composing my final post for Merck Manuals Vet Student Stories as a student veterinarian. I’m in shock that these... More Featured [merckvetmanual.com]
It is possible to prevent infection in unborn puppies by using a specific daily protocol of fenbendazole (your veterinarian can provide details) or with selamectin (Revolution®). [veterinarypartner.com]
- Fatigue
A range of symptoms are connected with VLM: fatigue weight loss anorexia fever cough pneumonia bronchospasm abdominal pain headache rash seizures (rarely) A swollen liver, infected lymph nodes, and wheezing may also be present. [news-medical.net]
However, some people experience mild symptoms, such as: a cough a high temperature of 38C or above headaches stomach pain In rare cases, the roundworm larvae infect organs such as the liver, lungs, eyes or brain and cause severe symptoms, such as: fatigue [nhs.uk]
This wandering causes inflammation and can result in a myriad of syptoms such as fatigue, anorexia, pneumonia, fever, coughing, abdominal pain, headaches, rashes, and even occasionally seizures. A child with ocularis larva migrans. [parasitophilia.blogspot.com]
- Chills
A 44-year-old man presented with chills, eruptions, marked leukocytosis (31,400/microlitter), and eosinophilia (eosinophil, 72%). Multiple liver nodules were detected as low-density lesions on computed tomography (CT). [ncbi.nlm.nih.gov]
[…] anyone simultaneously taking other medications confusion severe diarrhea hallucinations irritability loss of appetite severe nausea and vomiting numbness or tingling in the hands or feet skin rash itching muscle and joint aches blurred or yellow vision chills [web.stanford.edu]
- Plethora
Humans are amongst a plethora of possible intermediate animal hosts. [statpearls.com]
Respiratoric
- Bronchospasm and Wheezing
Lung involvement can result in bronchospasm and wheezing. [statpearls.com]
Gastrointestinal
- Abdominal Pain
We report a case of T canis infection manifested as abdominal pain with diarrhea, eosinophilia, and diffuse noncavitating nodules in an immunocompetent adult. [ncbi.nlm.nih.gov]
Clinical manifestations of toxocarosis include frequently a marked hypereosinophilia and also asthenia, abdominal pain or asthma. [bordier.ch]
Toxocaral visceral larva migrans is characterised by fever, malaise, cough and bronchospasm, abdominal pain, and occasionally failure to thrive. Hepatosplenomegaly, lymphadenitis, and bronchopulmonary signs predominate. [bmj.com]
Other possible symptoms include cough, poor sleep, headaches, and abdominal pain. Children may show signs of infected lymph nodes, a swollen liver, or wheezing. [news-medical.net]
- Worms in Stool
*If seen adult worms in stool- obvious infection. (hit or miss, because will mostly likely need to be a dead worm) *Fecal flotation is preferred- if taken in pre-patent period, we will not see eggs in feces. [quizlet.com]
Liver, Gall & Pancreas
- Hepatosplenomegaly
Hepatosplenomegaly, lymphadenitis, and bronchopulmonary signs predominate. Severe infection may cause myocarditis or respiratory failure. Focal or generalised seizures may occur. [bmj.com]
In VLM, which occurs mostly in preschool children, the larvae invade multiple tissues (commonly liver, lung, skeletal muscle, occasionally heart) and cause various nonspecific symptoms (e.g. fever, myalgia, weight loss, cough, rashes, hepatosplenomegaly [cdc.gov]
An exam may be notable for hepatosplenomegaly, which can serve as a clue for clinicians that the presentation is not simple viral gastroenteritis. Lung involvement can result in bronchospasm and wheezing. [statpearls.com]
The larvae invade multiple tissues and clinical features include fever, anorexia, abdominal pain, weight loss, cough, wheezing, pleural effusion, hepatosplenomegaly, urticaria, subacute meningitis/encephalitis, seizures, monoarthritis, cutaneous vasculitis [patient.info]
Skin
- Larva Migrans
We consider that the differential diagnosis of multiple liver nodules should include visceral larva migrans. [ncbi.nlm.nih.gov]
Larvae remain most frequently located in the liver and the lungs but can also cause serious ocular damage by migrating into the retina (ocular larva migrans). [bordier.ch]
Eyes
- Visual Impairment
Involvement is typically unilateral (affecting one eye) and associated visual impairment usually presents with uveitis, retinitis, or endophthalmitis; permanent visual damage or blindness can occur. [cdc.gov]
Musculoskeletal
- Myalgia
In VLM, which occurs mostly in preschool children, the larvae invade multiple tissues (commonly liver, lung, skeletal muscle, occasionally heart) and cause various nonspecific symptoms (e.g. fever, myalgia, weight loss, cough, rashes, hepatosplenomegaly [cdc.gov]
Visceral Larva Migrans is caused by chronic or heavy infections and may cause: Common Less Common gastrointestinal and intraabdominal dysfunction headache weakness lethargy fever coughing asthma pneumonia eosinophilia myalgia (muscle pain) seizures urticaria [web.stanford.edu]
Twenty-eight (40%) of the 70 patients reported symptoms such as cough ( n = 10), itching ( n = 4), weakness ( n = 2), myalgia ( n = 3), and fever ( n = 1), but there were no symptoms or signs suggesting the possibility of a specific disease. [ajronline.org]
Neurologic
- Neglect
Abstract Toxocara canis is an intestinal nematode of canids with a worldwide distribution, causing an important but neglected parasitic zoonosis in humans. [ncbi.nlm.nih.gov]
Key words: Larva Migrans; Toxocara canis; Neglected Diseases; Diagnosis; Colombia RESUMEN Introducción. [scielo.org.co]
Palabras clave (en_US) Larva Migrans; Toxocara canis; Neglected Diseases; Diagnosis; Colombia Resumen (es_ES) Introducción. [revistas.unal.edu.co]
- Encephalopathy
Central nervous system disease is rare but can be severe and range from eosinophilic meningitis to fulminant meningoencephalitis, presenting with seizures, encephalopathy or neuropsychiatric symptoms. [7] [8] Evaluation Diagnosis of toxocariasis is difficult [statpearls.com]
CNS involvement can lead to seizures, neuropsychiatric symptoms, or encephalopathy. There is an increasing appreciation that more subtle clinical manifestations might also arise as a result of long-term exposure to the migrating juveniles. [dx.doi.org]
Workup
The patients underwent extensive blood and CSF workup as well as MRI of the spinal cord and brain. Only 2 patients had a high eosinophil count in the CSF, although blood eosinophilia was seen in 6 patients. [ncbi.nlm.nih.gov]
The people with epilepsy who consented for further workup were then called to our institute for evaluation regarding cause of epilepsy. [annalsofian.org]
Microbiology
- Fasciola Hepatica
Considerations include ascariasis (Löffler’s syndrome), trichinosis, strongyloides, onchocerciasis, schistosomiasis, paragonimus, entamoeba histolytica, and Fasciola hepatica. The central differential for OLM is retinoblastoma. [statpearls.com]
Also Toxocara cati, Ascaris suum, Trichinella spiralis, Ancylostoma caninum, Dipylidium caninum, Fasciola hepatica, Leishmania mexicana, Trypanosoma cruzi, Giardia intestinalis, Trichomonas vaginalis and Acanthamoeba spp. antigens were tested. [parasitesandvectors.biomedcentral.com]
- Entamoeba Histolytica
histolytica, hydatid and hookworm infections. [ncbi.nlm.nih.gov]
Considerations include ascariasis (Löffler’s syndrome), trichinosis, strongyloides, onchocerciasis, schistosomiasis, paragonimus, entamoeba histolytica, and Fasciola hepatica. The central differential for OLM is retinoblastoma. [statpearls.com]
Treatment
Effectiveness of selected stages of wastewater treatment in elimination of eggs of intestinal parasites. [revistabiomedica.org]
We found that treatment with 300 or 400 MPa for 60 s killed 100% of eggs using embryonation as the standard. Treatment with 250, 241, and 207 MPa was less effective and killed 80%, 56%, and 8% of eggs, respectively. [ncbi.nlm.nih.gov]
Pictured below are different levels of treatment. Treatments will vary based on your pets' age, production level and activity level. [en.wikipedia.org]
Prognosis
Prognosis The prognosis for VLM is generally good; however, chronic disease has potential correlations with both epilepsy and cognitive delay. [statpearls.com]
Those that require surgical intervention typically have a poorer prognosis and visual acuity. [eyewiki.aao.org]
Prognosis and complications In the ocular form, outcome is variable but uniocular visual loss is not uncommon. In the visceral form, outcome is usually good but marked organ damage and even death can occur in extreme cases. [patient.info]
A study with longer follow up is required to see how multifocal granulomata differ in prognosis from usual focal granuloma of Toxocara. [wjgnet.com]
Etiology
The present study indicates that direct contact with T. canis infected dogs may be a potential etiological factor for human toxocariasis. [ncbi.nlm.nih.gov]
The etiology of visceral larva migrans. I. Diagnostic morphology of infective second-stage Toxocara larvae. J Parasitol 1956;42(4 Section 1):349–362. 10. Nichols RL. The etiology of visceral Larva migrans. II. [parasitol.kr]
Epidemiology
A clinical and epidemiological questionnaire and body mass index were used to assess the risk factors associated with human toxocariasis in 108 children with an age range of 2-16 years. [ncbi.nlm.nih.gov]
The epidemiology and public health importance of toxocariasis: A zoonosis of global importance. Int J Parasitol. 2013;43:999-1008. https://doi.org/10.1016/j.ijpara.2013.07.004 Fan CK, Liao CW, Cheng YC. [revistabiomedica.org]
Thorough information is also required especially on the symptoms and the epidemiological history of the patients. [ijmm.org]
Pathophysiology
The diagnostic approach, especially parasitic serological data, which must be carefully interpreted, are discussed; in addition, the possible pathophysiological mechanisms involved in the production of ascites are evoked. [ncbi.nlm.nih.gov]
Pathophysiology Clinical disease is due to parasitic nematode larva migration through tissues. The signs and symptoms differ based on the affected organ and the host inflammatory response. [statpearls.com]
Pathophysiology In humans, after contact with infected fecal material, the roundworm migrates throughout various organs but is unable to sexually mature. Reactive inflammatory processes lead to the organism's encapsulation. [eyewiki.aao.org]
In regard to nematodes, a role for eosinophils in the pathophysiology of Toxocara canis infection has been reported. [frontiersin.org]
Prevention
The best treatment for puppies is pyrantel pamoate to prevent the larvae from reproducing and causing disease. There are several ways to prevent a T. canis infection in both dogs and humans. [en.wikipedia.org]
Detection of circulating antigens helps provide appropriate and timely treatment and prevents irreversible damage. [ncbi.nlm.nih.gov]
Owing to transmission of the infection from bitches to puppies, preventive anthelmintic treatment of newborn puppies is strongly recommended. [parasitetesting.co.uk]