Including all cases detected on the first and second routine NBS test, we found that 32 of 109 (29.4%) had transient hypothyroidism. [karger.com]

All preterm babies with permanent or transient hypothyroidism were detected by the first TSH cut-off of 6 mU/L. Only one infant with a birth weight CONCLUSIONS: The incidence of permanent CHT in preterm infants is similar to term infants. [ncbi.nlm.nih.gov]

DEFINITIONS OF TRANSIENT HYPOTHYROIDISM The definition of transient hypothyroidism in the medical literature is variable. [pediatrics.aappublications.org]

Evidence summary Feeding difficulties, inadequate weight gain, and unusual physical exam findings may lead providers to assess thyroid function in newborns. [mdedge.com]

Some symptoms and signs of hypothyroidism in older children and adolescents are similar to those of adults (eg, weight gain; fatigue; constipation; coarse, dry hair; sallow, cool, or mottled coarse skin—see Hypothyroidism : Symptoms and Signs ). [msdmanuals.com]

Symptoms and signs include the following: Decreased activity Large anterior fontanelle Poor feeding and weight gain Small stature or poor growth Jaundice Decreased stooling or constipation Hypotonia Hoarse cry Often, affected infants are described as [emedicine.medscape.com]

Clinical symptoms include severe mental retardation, impaired skeletal development, short stature, and myxedema. A deficiency of thyroid hormone present at birth. [icd10data.com]

TG and TPO antibodies occur commonly in patients of Hashimoto’s thyroiditis and myxedema [ 4 ]. [alliedacademies.org]

Signs include the following: Coarse facial features Macroglossia Large fontanelles Umbilical hernia Mottled, cool, and dry skin Developmental delay Pallor Myxedema Goiter Anemia may occur, due to decreased oxygen carrying requirement. [emedicine.medscape.com]

[…] to thrive Illustration by Emily Roberts, Verywell Causes There are two main forms of congenital hypothyroidism: permanent congenital hypothyroidism and transient congenital hypothyroidism. [verywell.com]

Most of these children eventually ended up in institutional care. 3 month old infant with untreated CH; picture demonstrates hypotonic posture, myxedematous facies, macroglossia, and umbilical hernia Close up of face, showing myxedematous facies, macroglossia [en.wikipedia.org]

Symptoms Feeding difficulties Somnolence Lethargy Low frequency of crying Constipation Signs Large fontanelles Myxoedema - with coarse features and a large head and oedema of the genitalia and extremities Nasal obstruction Macroglossia Low temperature [patient.info]

[…] and hypothyroidism remains undiagnosed or untreated, it usually slows CNS development moderately to severely and may be accompanied by low muscle tone, sensorineural hearing loss, prolonged hyperbilirubinemia, umbilical hernia, respiratory distress, macroglossia [msdmanuals.com]

Signs include the following: Coarse facial features Macroglossia Large fontanelles Umbilical hernia Mottled, cool, and dry skin Developmental delay Pallor Myxedema Goiter Anemia may occur, due to decreased oxygen carrying requirement. [emedicine.medscape.com]

Examination may show macroglossia, cold or mottled skin, hypothermia, edema, wide fontanel, open sutures, flat nasal bridge, protuberant abdomen, umbilical hernia, delayed reflexes, and hypotonia. Presence of goiter indicates DH. [dovepress.com]

Previous reports suggest that biallelic mutations of DUOX2 cause permanent congenital hypothyroidism and that monoallelic mutations cause transient congenital hypothyroidism. [ncbi.nlm.nih.gov]

All infants were treated with thyroxine, which was subsequently withdrawn from three. Following thyroxine withdrawal, one infant resumed normal thyroid function and two developed compensated hypothyroidism. [ncbi.nlm.nih.gov]

Screeing for phenylketonuria and congenital hypothyroidism in 5.8 million neonates in China. Clin. J. Prev. Med., 38 (2):99–101. Google Scholar Hrytsiuk, I., Gilbert, R., Logan, S., Pindoria, S., Brook, C.G., 2002. [link.springer.com]

This is part of the UK Newborn Screening Programme (the blood is also analysed for phenylketonuria, cystic fibrosis and sickle cell disease). [ 4, 5 ] A high TSH and low T4 confirm the diagnosis. [ 6 ] Thyroglobulin levels can also be measured - usually [patient.info]

[…] amount of blood is placed on a filter type paper that is tested for an array of tests depending on the errors in metabolism endemic to a particular area and some standard tests like thyroid function, hemoglobinopathies like sickle cell, galactosemia and phenylketonuria [quizlet.com]

Phenylketonuria, congenital hypothyroidism and haemoglobinopathies: public health issues for a Brazilian newborn screening program. Cad Saude Publica. 2012;28(9):1623–1631. 10. Skordis N, Toumba M, Savva SC, et al. [dovepress.com]

Children with a normal thyroid ultrasound result but abnormal thyroid-function tests had a perchlorate-discharge test. Children with normal results had repeat thyroid-function tests 4 and 6 months later. [pediatrics.aappublications.org]