Nevertheless, peculiar clinical presentations may require additional work-up to rule out life-threatening conditions, and dermatological consultation and histological examination are required for the final diagnosis. [unboundmedicine.com]

We report an exceedingly unusual presentation of transient neonatal pustular melanosis, suggesting the importance of a systematic diagnostic approach to allow a confident recognition of this benign condition. [ncbi.nlm.nih.gov]

The lesions often present as, or evolve into, a pigmented macule and persist from three weeks to three months. [uthscsa.influuent.utsystem.edu]

The lesions of transient neonatal pustular melanosis are present at birth. [thehealthscience.com]

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The initial lesions usually disappear spontaneously within the first 2 weeks of life without long-term sequelae, and no treatment is required. [link.springer.com]

Clinical recognition of this disease can help physicians avoid unnecessary diagnostic testing and treatment for infectious etiologies because no specific therapy is recommended. [unboundmedicine.com]

Treatment includes topical anti-yeast agents such as nystatin, clotrimazole, and econazole. [hawaii.edu]

Prognosis Neonatal pustular melanosis is a completely benign condition that is not known to cause any long-term sequelae. [2] The prognosis is excellent. Postinflammatory pigmented macules resolve in 2-4 months. [emedicine.medscape.com]

Part I of this article reviews the presentation, prognosis, and treatment of the most common rashes that present during the first four weeks of life. [aafp.org]

Keywords: neonatal, transient, skin disease Introduction The majority of the dermatologic findings in neonates are physiological and transient so no treatment is required; parents can therefore be reassured about the good prognosis. [clinicaldermatology.eu]

It is a benign and self-limited disease, and the etiology is still unknown. We present a full-term female neonate with multiple vesiculopustular and pigmented macular lesions found immediately after her birth. [ncbi.nlm.nih.gov]

Clinical recognition of this disease can help physicians avoid unnecessary diagnostic testing and treatment for infectious etiologies because no specific therapy is recommended. [unboundmedicine.com]

College of Medicine, Korea University, Seoul, Korea Corresponding Author: Baik Lin Eun ,Email: 1 Copyright © 1999 by The Korean Pediatric Society ABSTRACT Transient neonatal pustular melanosis(TNPM) is a benign, self-limited, cutaneous disorder of unknown etiology [kjp.or.kr]

The brown macules may persist for several months. [3, 5] Epidemiology Frequency United StatesPreviously published incidence rates for transient neonatal pustular melanosis are 0.6% in white infants and 4.4% in African American infants. [thehealthscience.com]

Epidemiology US frequency Few reports of large numbers of screened infants are available; however, incidence has been reported to be as much as 2.2% in white infants and 4.4% in black infants. [emedicine.medscape.com]

Prospective study of erythema toxicum neonatorum: epidemiology and predisposing factors. Pediatr Dermatol. 2012 Mar-Apr;29(2):166-8 4. Rudnick CM, Hoekzema GS. Neonatal herpes simplex virus infections. Am Fam Physician. 2002 Mar 15;65(6):1138-42. [mdmag.com]

Epidemiologic study of the predisposing factors in erythema toxicum neonatorum. Dermatology. 2005;210(4):269–272. 5. Carr JA, Hodgman JE, Freedman RI, Levan NE. Relationship between toxic erythema and infant maturity. [aafp.org]

Although it is rare in Taiwan and Asian countries, transient neonatal pustular melanosis should always be considered when pustulosis is found in the neonatal period to prevent the use of unnecessary antibiotics. [ncbi.nlm.nih.gov]

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The information presented here is not intended to diagnose, treat, cure or prevent any disease. Read disclaimer. [gulfdoctor.net]

Robert A Schwartz, MD, MPH Professor and Head of Dermatology, Professor of Pathology, Pediatrics, Medicine, and Preventive Medicine and Community Health, Rutgers New Jersey Medical School; Visiting Professor, Rutgers University School of Public Affairs [emedicine.medscape.com]