[…] suspicious lesions or body fluids For further testing recommendations, see the Syphilis (Reverse Sequence) Testing Algorithm and the Syphilis (Traditional) Testing Algorithm Differential Diagnosis Genital chancre/ulcer (primary syphilis) Herpes simplex virus Chancroid [arupconsult.com]

Author information 1 Work Group Neglected Tropical Diseases, Infection Biology Unit, German Primate Center, Leibniz- Institute for Primate Research, Göttingen, Germany. 2 Department of Biology, Faculty of Medicine, Masaryk University, Brno, Czech Republic [ncbi.nlm.nih.gov]

PLoS neglected tropical diseases. 2008;2(1):e148–e. pmid:18235852 View Article PubMed/NCBI Google Scholar 8. Gray R, Mulligan C, Molini B, Sun E, Giacani L, Godornes C, et al. [journals.plos.org]

PLoS Neglected Trop Dis 2 : e148. ( 1996 ) DNA repeats identify novel virulence genes in Haemophilus influenzae. Proc Nat Acad Sci 93 : 11121 – 11125. ( 1996 ) R: a language for data analysis and graphics. [doi.org]

RECOMMENDED MEDIA For culture: 3 subspecies ( Treponema pallidum, Treponema carateum, and Treponema paraluiscuniculi have not been cultivated successfully in media or tissue culture). [catalog.hardydiagnostics.com]

Treponema carateum is the least invasive and causes only cutaneous disease. Treponema pallidum subspp pertenue and endemicum are intermediate in invasiveness and cause destructive lesions in bones and soft tissues. [ncbi.nlm.nih.gov]

T reponema pallidum subspp. pallidum, endemicum, and pertenue, the agents of venereal syphilis, endemic syphilis, and yaws, respectively, together with Treponema carateum, the agent of pinta, are primary pathogens of humans that have eluded in vitro cultivation [aac.asm.org]

cruzi macrophage infectivity potentiator protein) TPANIC_1033 Patatin family phospholipase 1st rank: VipD ( Legionella pneumophila phospholipase effector protein) 2nd rank: ExoU ( Pseudomonas aeruginosa type 3 secretion system effector protein) Our analyses [bmcstructbiol.biomedcentral.com]

Sutton Baltimore-9 T.p. pallidum United States 1970s Live strain Liver biopsy CDC Chicago B T.p. pallidum United States 1951 Live strain Lesion on prepuce CDC Dallas-1 T.p. pallidum United States 1988 Live strain Amniotic fluid CDC Grady T.p. pallidum [doi.org]