Presentation
Mostly, it presents as a papule or nodule, involving the skin of the face and scalp area. A central, dilated keratin plugged ostium with vellus hair(s) is often present. [ncbi.nlm.nih.gov]
Sebaceous glands may or may not be present. Lymphocytic or granulomatous inflammation may be present in the connective tissue stroma. [histopathology-india.net]
Entire Body System
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Asymptomatic
It presented as an asymptomatic, 10 mm deep sinus and histology showed keratin-filled cysts or sinuses lined by stratified squamous epithelium. [ncbi.nlm.nih.gov]
Elderly patient Localisation Head / face / forehead Description Primary Lesions Papule / skin color Pathophysiology tumors and proliferative diseases / appendageal tumors / hair follicle tumors / benign hair follicle tumors / trichofolliculoma Symptoms Asymptomatic [dermquest.com]
Trichofolliculomas generally are asymptomatic and are not associated with any systemic or other cutaneous diseases. Therefore, no treatment is required. [thefreelibrary.com]
The lesion was otherwise asymptomatic and had not previously been treated. The provisional clinical diagnosis was either a keratoacanthoma or a molluscum contagiosum. [journals.lww.com]
Ears
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Otalgia
We present a case of a 7-year old girl who presented with bloody otorrhea, aural fullness, and otalgia, in the irst pediatric report of trichofolliculoma of the external auditory canal. [semanticscholar.org]
Skin
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Normal Hair
In spite of the well known regressive changes of normal hair follicles during catagen and telogen, the possibility of corresponding changes in the trichofolliculoma has not yet been discussed in the literature. [ncbi.nlm.nih.gov]
Clinical images Images hosted on other servers: Gross description Solitary and nodular, may have multiple fine hairs protruding Microscopic (histologic) description Highly organoid hamartomatous lesions that recapitulate various phases of normal hair [pathologyoutlines.com]
This results in disorder of the normal-hair cycle. [ILLUSTRATION OMITTED] The clinical differential diagnosis for trichofolliculoma includes dermal nevus, basal cell carcinoma, and pilar sheath acanthoma. [thefreelibrary.com]
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Cutaneous Manifestation
Multiple facial angiofibromas: a cutaneous manifestation of Birt-Hogg-Dube syndrome. J Am Acad Dermatol. 2005;53(Suppl):108-111. 2009 Lippincott Williams & Wilkins, Inc. [journals.lww.com]
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Facial Angiofibroma
Multiple facial angiofibromas: a cutaneous manifestation of Birt-Hogg-Dube syndrome. J Am Acad Dermatol. 2005;53(Suppl):108-111. 2009 Lippincott Williams & Wilkins, Inc. [journals.lww.com]
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Furunculosis
Trichofolliculoma (ruptured) and secondary pyogranulomatous furunculosis in a rock hyrax. ( 28703675 ) 2017 3 Chronological changes in trichofolliculoma: Folliculosebaceous cystic hamartoma is not a very-late-stage trichofolliculoma. ( 28370423 ) 2017 [malacards.org]
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Dermatitis
PDF PD F PDF Download Next Article: Dermatitis Herpetiformis Dermatopathology [mdedge.com]
Psychiatrical
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Suggestibility
In the TF lesions, no features indicating the replacement of the regressing secondary hair follicles by any sebaceous elements were observed, thereby suggesting that FSCH is not a very-late-stage TF. 2017 Japanese Dermatological Association. [ncbi.nlm.nih.gov]
The finding of cohesive, branching keratinized squamous cell clusters admixed with sebaceous cells may suggest a diagnosis of trichofolliculoma, as was seen in the present case. [mayoclinic.pure.elsevier.com]
Findings in NLCS are reminiscent of fetal adipogenesis; pinocytosis and condensation of the plasma membrane and the many vascular elements in contact with adipocytes suggest a vascular origin of the adipose cells. [e-ijd.org]
Neurologic
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Tingling
Surrounding stroma does not have a basophilic tingle (seen in BCC ). DDx: Trichoblastoma. Basal cell carcinoma. Pilar sheath acanthoma. Images www: Trichofolliculoma DermNet Trichofolliculoma. (WC) See also Dermatologic neoplasms. [librepathology.org]
Workup
Workup Histologic Findings Following surgical excision, these tumors are found to consist of a dilated primary follicle lined by infundibular, stratified squamous epithelium and opening to the skin surface. [6] Low-power view of trichofolliculoma with [emedicine.medscape.com]
Treatment
Treatment Options Treatment options are summarized in Table I. Table I. [dermatologyadvisor.com]
What is the treatment of trichofolliculoma? Trichofolliculoma is a benign follicular tumour that requires no treatment. Occasionally they may be excised for cosmetic reasons or if they occur in functionally sensitive areas. [dermnetnz.org]
Prognosis
The prognosis is excellent. [emedicine.medscape.com]
What is the Prognosis of Trichofolliculoma? (Outcomes/Resolutions) The prognosis for Trichofolliculoma is excellent with appropriate treatment, since it is a benign tumor. [dovemed.com]
Etiology
TERMINOLOGY Definitions Hamartoma with prominent follicular differentiation ETIOLOGY/PATHOGENESIS Unknown Majority of cases are sporadic Likely represents a hamartoma rather than a true tumor CLINICAL ISSUES Epidemiology Incidence Rare Age Usually presents [basicmedicalkey.com]
While the etiology is largely known, it is considered to be a hamartoma with follicular differentiation that results when the pluripotent skin cells cease to differentiate into the hair follicle. [thefreelibrary.com]
Pathophysiology Although the precise etiology of trichofolliculoma is uncertain, these tumors are not associated with systemic disease or other skin disorders. [emedicine.medscape.com]
Etiology Pathophysiology The etiology of trichofolliculoma remains unclear. Systemic Implications and Complications Trichofolliculomas are benign hamartomas. [dermatologyadvisor.com]
Epidemiology
TERMINOLOGY Definitions Hamartoma with prominent follicular differentiation ETIOLOGY/PATHOGENESIS Unknown Majority of cases are sporadic Likely represents a hamartoma rather than a true tumor CLINICAL ISSUES Epidemiology Incidence Rare Age Usually presents [basicmedicalkey.com]
Epidemiology Frequency Trichofolliculoma represents an uncommon clinical entity. Race In reported cases, trichofolliculomas demonstrate no definitive racial predilection. [emedicine.medscape.com]
Pathophysiology
Case Overview trichofolliculoma Member Rated 0 Patient case no. 3133 Date added 30 June 2003 Patient details Age Elderly patient Localisation Head / face / forehead Description Primary Lesions Papule / skin color Pathophysiology tumors and proliferative [dermquest.com]
Pathophysiology Although the precise etiology of trichofolliculoma is uncertain, these tumors are not associated with systemic disease or other skin disorders. [emedicine.medscape.com]
Etiology Pathophysiology The etiology of trichofolliculoma remains unclear. Systemic Implications and Complications Trichofolliculomas are benign hamartomas. [dermatologyadvisor.com]
Prevention
An incomplete removal may result in its recurrence Cauterization (burning-off) of the nodule can be performed using a CO2 laser How can Trichofolliculoma be Prevented? Currently, there are no known methods to prevent Trichofolliculoma occurrence. [dovemed.com]
If laser treatment is attempted with deeper and multiple passes, recurrence can be prevented, but there is an increased risk of scarring. Electrosurgery can also be used, but hypopigmented scars may replace the lesions because of thermal effects. [dermatologyadvisor.com]