Presentation
A 41-year-old man was hospitalized, presenting increasing dyspnea and extensive ground-glass opacities on chest X-ray. Infection by human immunodeficiency virus was confirmed. [ncbi.nlm.nih.gov]
Infection is much more common in women than in men In women it usually presents with a vaginal discharge which may be offensive with an associated vulvitis/vaginitis. Men usually present as sexual contacts of women with infection. [hse.ie]
Entire Body System
- Pain
When present, symptoms may include vaginal discharge with strong odor, painful urination, and genital itching. [questdiagnostics.com]
Multivariate analyses revealed that increased days with ulcers (OR 0.1, 95% CI 0.04 to 0.5, p=0.002) and ulcer pain intensity (OR 0.08, 95% CI 0.007 to 1.1, p=0.05) remained significantly associated with decreased odds of TV infection. [ncbi.nlm.nih.gov]
Symptoms Men : White discharge from the penis and painful urination are possible symptoms. [richmondpractice.co.uk]
- Infertility
And these signals should not be ignored: trichomoniasis can increase the risk of contracting both herpes and HIV – as well as the risk of pelvic inflammatory disease, premature birth and low birth weight, and indeed infertility. [giantmicrobes.com]
Though it was once virtually ignored, T. vaginalis infection in men is now recognized as an important cause of nongonococcal urethritis and is associated with prostatitis and male infertility. [meridianbioscience.com]
While acute symptoms in women may include vaginitis, infections are often asymptomatic, but can persist and are associated with medical complications including increased HIV susceptibility, infertility, pre-term labor, and higher incidence of cervical [ncbi.nlm.nih.gov]
In women the infection can cause pelvic inflammatory disease, urethritis, infertility, as well as complications for newborns such as postabortal infection, low birth weight, and preterm delivery. [diagnostics.roche.com]
The use of culture method in routine diagnosis of T. vaginalisinfection is advocated as this will reduce cases of infertility resulting from undetected and untreated infection as well as the risk of HIV transmission and acquisition. [ajol.info]
- Swelling
The patient had no urethral discharge but had a penile swelling tht discharged pus. Microscopic examination and culture of the discharge showed the presence of T. vaginalis. [ncbi.nlm.nih.gov]
Infected men might experience urethral irritation and swelling, along with a characteristic discharge. Infected women can also experience irritation and swelling (sometimes referred to as "strawberry cervix"), as well as a frothy discharge. [bio390parasitology.blogspot.com]
[…] may have: Burning after urination or ejaculation Itching of urethra Slight discharge from urethra Occasionally, some men with trichomoniasis may develop: Swelling and irritation in the prostate gland ( prostatitis ). [nlm.nih.gov]
Occasionally they may also have swelling or irritation of the prostate gland (prostatitis) or swelling in the epididymis (epididymitis). [en.vircell.com]
- Candidiasis
Candidiasis can also occur during pregnancy and can cause infant thrush in children born to infected mothers. Treatment of these infectious forms of vaginitis is by appropriate antimicrobial… Read More [britannica.com]
Of the 35 HIV-seropositive FSWs, BV was detected in six (17.14%), candidiasis in six (17.14%), syphilis in five (14.28%) and HBsAg in two (5.71%). One (2.85%) HIV-positive FSW was positive for both candidiasis and syphilis. [doi.org]
In 1998, candidiasis was the most frequent infection, diagnosed in 22.5% of the tests. [scielo.br]
Light microscopy of a vaginal wet preparation at ×40 magnification was used to diagnose vaginal trichomoniasis and candidiasis on the basis of identifying motile trichomonads and yeast forms, respectively. [academic.oup.com]
- Disability
It has also been involved in some cases of intellectual disability. The recommended treatment is a 2g metronidazole oral single dose, even for asymptomatic patients. [ncbi.nlm.nih.gov]
The store will not work correctly in the case when cookies are disabled. [fitzgerald-fii.com]
Your display settings disabled the content of this page (blocked by marine only ). Change the options on top of this page if desired. Back to taxon search [marinespecies.org]
The store will not work correctly in the case when cookies are disabled. One of the most common sexually transmitted diseases among women, a relationship with Trichomonas can be hard to handle. Featured on NPR's popular game show Wait Wait.. [giantmicrobes.com]
Although rare, the infection can be transmitted to the baby during delivery. suggested that your child’s risk of developing an intellectual disability increases if you have trich during pregnancy. [healthline.com]
Gastrointestinal
- Abdominal Pain
Vaginitis with a purulent discharge is the prominent symptom, and can be accompanied by vulvar and cervical lesions, abdominal pain, dysuria and dyspareunia. The incubation period is 5 to 28 days. [cdc.gov]
'Lower abdominal pain syndrome' had low sensitivity (26%-41%) and PPV (8%-23%) but moderate specificity (66%-68%) and high NPV (74%-93%) among women attending WWC, and moderate-high sensitivity (67%-79%) and NPV (62%-86%) but low specificity (26%-28%) [ncbi.nlm.nih.gov]
Symptoms include vaginal discharge (which is often diffuse, malodorous, yellow-green), dysuria, itching, vulvar irritation and abdominal pain. [clinicaltrials.gov]
When symptoms do occur, they can include a foul- or strong-smelling vaginal discharge yellow or grayish-green in color, mild vaginal itching, pain during urination, and in rare cases, lower abdominal pain. [healthychildren.org]
Doing so can cause: Severe nausea Abdominal pain Vomiting Avoid sexual intercourse until you have finished treatment. Your sexual partners should be treated at the same time, even if they have no symptoms. [nlm.nih.gov]
Skin
- Ulcer
Multivariate analyses revealed that increased days with ulcers (OR 0.1, 95% CI 0.04 to 0.5, p=0.002) and ulcer pain intensity (OR 0.08, 95% CI 0.007 to 1.1, p=0.05) remained significantly associated with decreased odds of TV infection. [ncbi.nlm.nih.gov]
Superficial ulceration of the epithelium can occur. Transmission issues: Can survive up to 45 minutes on clothing, washcloths, and in bathwater. The presence of infection enhances the acquisition of HIV infection. [hopkinsguides.com]
By speculum shows small red ulcers in the vaginal wall or cervix Dot-blot DNA hybridization assay Vaginal scraping ~> pap or culturd Vaginal irrigatation ~> culture Metrinadazole (hero of the parasites we took) Can be given to a pregnant lady Male condom [quizlet.com]
- Pruritus
Is noticed vulvar erythema, edema, and pruritus, also is noted the characteristic erythematous, punctate epithelial papillae or “strawberry” appearance of the cervix. Vaginal pH was 6.2. [heighpubs.org]
Trichomonas vaginalis Etymology: Gk, thrix + monas + L, vagina, sheath a motile protozoan parasite that causes vaginitis with a copious malodorous discharge and pruritus. See also trichomoniasis. [medical-dictionary.thefreedictionary.com]
Acute infections are characterised by severe pruritus, vaginitis, vulvitis with dysuria and dyspareunia, and hemorrhagic spots on the mucosa (in 2% of patients) which results in colpitis macularis or petechiae (strawberry cervix). [msdsonline.com]
- Erythema
Erythema and discharge were the most frequent abnormal signs (58.6% and 56.0%). Not a single T. vaginalis-positive sample was detected using wet mount microscopy, culture or APTIMA T. vaginalis assay. [ncbi.nlm.nih.gov]
Is noticed vulvar erythema, edema, and pruritus, also is noted the characteristic erythematous, punctate epithelial papillae or “strawberry” appearance of the cervix. Vaginal pH was 6.2. [heighpubs.org]
Cervical mucopurulence, erythema, and friability have been observed. 7, 23 T vaginalis may be associated with cervical cancer; however, confounding factors, such as co-infection with HPV, have not been well controlled for in some of these studies. 25 [sti.bmj.com]
- Petechiae
Acute infections are characterised by severe pruritus, vaginitis, vulvitis with dysuria and dyspareunia, and hemorrhagic spots on the mucosa (in 2% of patients) which results in colpitis macularis or petechiae (strawberry cervix). [msdsonline.com]
- Blister
The odds of TV infection were significantly associated with high blister counts (OR 4.0, 95% CI 1.6 to 28, p=0.01), ulcer pain (OR 0.4, 95% CI 0.2 to 0.7, p=0.003), number of days with ulcers (OR 0.4, 95% CI 0.2 to 0.8, p=0.006), sought treatment before [ncbi.nlm.nih.gov]
Call your doctor at once if you have: diarrhea; painful or difficult urination; trouble sleeping, depression, irritability; headache, dizziness, weakness; a light-headed feeling (like you might pass out); or blisters or ulcers in your mouth, red or swollen [drugs.com]
Urogenital
- Dysuria
Female: Symptoms: Offensive vaginal odour Abnormal vaginal discharge – thick/thin/frothy and yellow-green Itchiness or soreness of the vulva Dyspareunia Dysuria Signs: Abnormal vaginal discharge – thick/thin/frothy and yellow-green Vulvitis Vaginitis [teachmeobgyn.com]
Symptoms include vaginal discharge (which is often diffuse, malodorous, yellow-green), dysuria, itching, vulvar irritation and abdominal pain. [clinicaltrials.gov]
METHODS: Women with recurrent UTIs, defined as the presence of lower urinary tract symptoms (dysuria, frequency and urgency) and three positive urine cultures on voided urine specimens in the previous year, were enrolled prospectively from January 2013 [ncbi.nlm.nih.gov]
Vaginitis with a purulent discharge is the prominent symptom, and can be accompanied by vulvar and cervical lesions, abdominal pain, dysuria and dyspareunia. The incubation period is 5 to 28 days. [cdc.gov]
- Urethral Discharge
The patient had no urethral discharge but had a penile swelling tht discharged pus. Microscopic examination and culture of the discharge showed the presence of T. vaginalis. [ncbi.nlm.nih.gov]
Strawberry cervix – punctate and papilliform appearance Male: Symptoms: Urethral discharge Dysuria Urinary frequency Pain or itching around the foreskin Signs: Urethral discharge Balanoposthitis – inflammation of the glans penis (rare) Investigations [teachmeobgyn.com]
Men might notice urethral discharge, burning after urination or ejaculation, and/or itching or irritation inside the penis. When infected, sex can become unpleasant. [paho.org]
Of 103 Tanzanian men with trichomoniasis, dysuria occurred in 42%; only five men complained of urethral discharge. 19 Finally, trichomoniasis was diagnosed in 66 of 410 men from the Central African Republic with urethral discharge. 8 In men, urethral [sti.bmj.com]
- Dyspareunia
Vaginal complaints were more common among women with T. vaginalis, but only dyspareunia had significant association. [ncbi.nlm.nih.gov]
Vaginitis with a purulent discharge is the prominent symptom, and can be accompanied by vulvar and cervical lesions, abdominal pain, dysuria and dyspareunia. The incubation period is 5 to 28 days. [cdc.gov]
Female: Symptoms: Offensive vaginal odour Abnormal vaginal discharge – thick/thin/frothy and yellow-green Itchiness or soreness of the vulva Dyspareunia Dysuria Signs: Abnormal vaginal discharge – thick/thin/frothy and yellow-green Vulvitis Vaginitis [teachmeobgyn.com]
Clinical aspects Persistentvaginitis, 50% asymptomatic Discharge 75% Vulvar itching and burning 50% Dyspareunia 50% Dysurea %0% Bad odor 10% 13. [slideshare.net]
- Urethral Disease
Complications are rare, but can potentially lead to genitourinary inflammation disease, sterility, scanty, clear to mucopurulent discharge, dysuria, non-gonococcal urethritis, prostatitis, balanoposthitis, epididymitis, and urethral disease(4). [msdsonline.com]
Complications are rare, but can potentially lead to genitourinary inflammation disease, sterility, scanty, clear to mucopurulent discharge, dysuria, non-gonococcal urethritis, prostatitis, balanoposthitis, epididymitis, and urethral disease ( 4 ). [phac-aspc.gc.ca]
Neurologic
- Burning Sensation
Indeed, men can carry the disease unknowingly for years – though some men do develop itching and burning sensations which demand attention. Fortunately, it’s very easy to break up with Trich: one dose of antibiotics usually does the trick. [giantmicrobes.com]
Common symptoms in men include penis irritation, mild discharge and burning sensation after urination or ejaculation, while women experience frothy, yellow-green vaginal discharge with strong odor. [livestrong.com]
Workup
Trichomoniasis workup. Medscape. Available online at http://emedicine.medscape.com/article/230617-workup. Accessed February 2017. (2016 November). Advances in laboratory detection of Trichomonas vaginalis (updated). [labtestsonline.it]
Considering the suboptimal sensitivity of the wet mount, routine screening using culture may soon become included in the diagnostic workup, especially when high-prevalence populations are being screened. [doi.org]
Treatment
Treatment of trichomoniasis Metronidazole was originally synthesised and approved for the treatment of trichomoniasis in 1959 25. [nature.com]
Patients with disease unresponsive to first-line treatments pose a major challenge, as therapeutic options are limited. [ncbi.nlm.nih.gov]
Prognosis
Prognosis Spontaneous resolution of T. vaginalis is known to occur at relatively high rates (36-69%) in men[3]. [patient.info]
What Is The Prognosis? Treatment with metronidazole produces a cure in about 95% of patients. Prevention Important preventive measures include regular use of latex condoms or abstaining from sexual activity. [healthychildren.org]
Outlook / Prognosis What can I expect if I have this condition? Trichomoniasis is a very common STI that goes away with proper treatment. [my.clevelandclinic.org]
Control of T vaginalis may represent an important means of slowing HIV transmission, particularly among African Americans. [37] Prognosis Recommended metronidazole therapy regimens have produced a 90-95% cure rate in randomized clinical trials. [9] The [emedicine.medscape.com]
Etiology
We hypothesize that an ascending trichomonal infection may have played an etiologic role in the development of their acute disease. [ncbi.nlm.nih.gov]
Trichomoniasis represents 30% of non-viral sexually transmitted infections worldwide; its etiological agent is the protozoan parasite Trichomonas vaginalis. [ojs.southfloridapublishing.com]
Epidemiology
SETTING: Molecular typing methods previously identified two genetically distinct subpopulations for T. vaginalis; however, few molecular epidemiological studies have been performed. [ncbi.nlm.nih.gov]
Utilization of polymerase chain reaction-based diagnostics has enhanced our understanding of the epidemiology of T. vaginalis both at the population level and in sexual partners. [doi.org]
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Pathophysiology
Pathophysiology Trichomonas vaginalis is transmitted through unprotected vaginal sexual intercourse – it is not passed on through oral or anal sex. [teachmeobgyn.com]
The host-parasite interaction and pathophysiological processes of trichomonosis remain incompletely understood. [ncbi.nlm.nih.gov]
Useful For Suggests clinical disorders or settings where the test may be helpful Detection of Trichomonas vaginalis in female patients Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory [mayomedicallaboratories.com]
Prevention
This critical review updates the state of the art on advances in T. vaginalis diagnostics and strategies for treatment and prevention of trichomoniasis. [ncbi.nlm.nih.gov]
Centers for Disease Control and Prevention. Available online at http://www.cdc.gov/std/trichomonas/STDFact-Trichomoniasis.htm. Accessed February 2017. Centers for Disease Control and Prevention: Trichomonas Fact Sheet. [labtestsonline.it]
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