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Tropical Myositis

Pyomyositis %2F Tropical Pyomyositis


Presentation

  • We describe a renal transplant recipient who presented with tropical myositis and acute allograft dysfunction 2(1/2) years after transplantation. Graft biopsy showed immune-complex crescentic glomerulonephritis.[ncbi.nlm.nih.gov]
  • Colour plates and line drawings are present throughout along with tables of key information.[books.google.com]
  • It is a rare presentation in which the patient has progressed from Stage I to Stage III without a Stage II where pus formation is present.[astrocyte.in]
  • The importance of immunocompetence and its impact on the presentation of pyomyositis is demonstrated by our present case. Hematologic malignancies are known to be associated with pyomyositis.[jmedicalcasereports.biomedcentral.com]
Pathologist
  • Kradin is also an Associate Pathologist at Massachusetts General Hospital in the Immunopathology Unit. His techniques include tissue culture and immunocytochemistry, flow cytometry, Northern blotting and immunocytochemistry. Dr.[books.google.com]
Laboratory Technician
  • Abbreviations AML: Acute myeloid leukemia MRI: Magnetic resonance imaging Declarations Acknowledgments The authors would like to acknowledge the contribution of the doctors, nurses and laboratory technicians in the Departments of Radiology, Microbiology[jmedicalcasereports.biomedcentral.com]
Anterior Uveitis
  • An unusual patient of tropical pyomyositis, who developed pleuropericardial effusion and anterior uveitis, is described. Such complications of this disease have not been reported in the literature reviewed.[ncbi.nlm.nih.gov]
Myopathy
  • Other parasitic myopathies such as trichinosis and cysticercosis are acquired through consumption of poorly cooked meats.[mja.com.au]
  • […] research laboratories of Boston Children's and other institutions, focuses on the description of novel mutations in patients with neuromuscular diseases and the application of new technologies to explore the pathogenesis and treatment of congenital myopathies[books.google.com]
  • .- ) muscular dystrophies and myopathies ( G71 - G72 ) myopathy in amyloidosis ( E85.- ) myopathy in polyarteritis nodosa ( M30.0 ) myopathy in rheumatoid arthritis ( M05.32 ) myopathy in scleroderma ( M34.- ) myopathy in Sjögren's syndrome ( M35.03 )[icd10data.com]
  • .- ) muscular dystrophies and myopathies ( G71-G72 ) myopathy in: · amyloidosis ( E85.- ) · polyarteritis nodosa ( M30.0 ) · rheumatoid arthritis ( M05.3 ) · scleroderma ( M34.- ) · Sjögren's syndrome ( M35.0 ) · systemic lupus erythematosus ( M32.- )[apps.who.int]
Myalgia
  • The most common presentation was localised myalgia (100%), fever (96.7%) generalized myalgia (56.7%), arthralgia (40%), pain in abdomen (33.3%) and breathlessness (30%). Extramuscular complications were present in 50% cases.[ncbi.nlm.nih.gov]
  • DD DVT Cellulitis Haematoma Rupture of Muscle/Tendon Polymyositis Leptospirosis(Diffuse myalgia wit severe LFT disturbances) 23. INVESTIGATIONS Muscle biopsy with culture Pus for C/S Blood C/S(Sterile in 90%) CT/MRI/X-RAY 24.[slideshare.net]
  • The patient reported asthenia and diffuse myalgia, beginning 15 days prior to admission, without association with other signs or symptoms, obtaining partial improvement with analgesics.[clinmedjournals.org]
  • There had been no myalgia. The patient had grown up in Queensland and was living in Innisfail, but had travelled around Australia in the 3 previous years, visiting Western Australia, New South Wales and Victoria.[mja.com.au]
Muscle Tenderness
  • Although myositis can cause muscle aches and muscle tenderness, weakness is usually the dominant symptom. In some cases, myositis is a short-term problem that goes away after a few days or weeks.[health.harvard.edu]
  • Occasionally, the stage of invasion by Cysticercus cellulosae is characterised by fever, muscle tenderness, and eosinophilia and needs to be differentiated from tropical pyomyositis.[pmj.bmj.com]
Muscle Swelling
  • Imaging Electromyography Short duration, low amplitude polyphasic potentials Ultrasonography First imaging investigation usually Characteristic features are Muscle swelling; Hypoechoic areas in the muscle belly Heterogenous hypoechoic areas Hyperechoic[boneandspine.com]
Foot Drop
  • The white arrow shows wasting of the tibialis anterior muscle, which caused foot drop.[mja.com.au]
  • O/E Pt well built Not pale/icteric/cyanosed/clubbing/sig gen lymphadenopathy Vitals Normal CVS,RS,Abdomen—Normal Rt LL- swollen,erythematous,warm,tense,tender Rt foot drop Power 1/5 sensation intact Plantar Flexor Injection marks found around inguinal[slideshare.net]

Workup

  • However, there is no microbiological evidence for the etiological agent for pyomyositis in our case as bacteriological workup was inconclusive. Trichinella was the only pathogen isolated.[jgid.org]
Mycobacterium Avium Complex
  • .: Mycobacterium avium complex infections in patients with the acquired immunodeficiency syndrome. Ann. Intern. Med. 105 :184, 1986 PubMed CrossRef Google Scholar 24.[link.springer.com]

Treatment

  • Renal function did not improve despite treatment with antibiotics, methylprednisolone pulse therapy, and cyclophosphamide. He died of septicemia.[ncbi.nlm.nih.gov]
  • Treatment with albendazole led to a slow and incomplete recovery, but treatment with steroids caused life-threatening deterioration.[mja.com.au]
  • Stay at the forefront of your field with updated treatment methods throughout, as well as an increased focus on patients with skin of color.[books.google.com]
  • Though our patient was in the latter part of stage 2 when he sought treatment initially, his condition deteriorated quickly to stage 3.[jmedicalcasereports.biomedcentral.com]

Prognosis

  • PROGNOSIS CFR 0.5 to 10% 26. THANK YOU 27.[slideshare.net]
  • The prognosis remains excellent if promptly treated.[ncbi.nlm.nih.gov]
  • The prognosis remains excellent if the disease is promptly identified and treated correctly. Chattopadhyay Bitoti, Mukhopadhyay Mainak, Chatterjee Atri, Biswas Pijush Kanti, Chatterjee Nandini, et al. (2013) Tropical pyomyositis.[clinmedjournals.org]
  • Treatment and prognosis Depending on the infective agent systemic antibiotics are administered. If an abscess has formed, then it should usually be drained either surgically or percutaneously.[radiopaedia.org]
  • Ryle JA: The natural history, prognosis and treatment of staphylococcal fever. In: The Natural History of Disease. Oxford University Press, Oxford, p 226, 1936. (Reprinted from Guy's Hospital Reports, 1930).[isradiology.org]

Etiology

  • Part II (Etiology and Mechanisms) covers advances in the immunopathology and viral etiology of PM/DM along with a frequently recognized entity: inclusion body myositis.[books.google.com]
  • The identification of one predisposing cause should not stop the etiologic search for others, because underlying subclinical sinister causes may be discovered that require urgent intervention.[jmedicalcasereports.biomedcentral.com]
  • Mad cow's disease (bovine spongioform encephalopathy bse ) is a very serious incurable disease often with progressive psychological and mental problems associated with rigidity and movement disorders of the extremities fortunately now that we know the etiology[healthtap.com]
  • Concerning the supposed etiologic association between Ancylostoma duodenale infection and TP, among the 35 patients with TP the stool examination of 22 (62.8%) revealed the presence of eggs of A. duodenale .[link.springer.com]

Epidemiology

  • ISSN: 0950-2688 EISSN: 1469-4409 URL: /core/journals/epidemiology-and-infection Unfortunately you do not have access to this content, please use the Get access link below for information on how to access this content.[cambridge.org]
  • Staphylococcal pyomyositis in a temperate region: epidemiology and modern management. Medical journal of Australia. 2008 Sep 15;189(6):323. Pyomyositis UpToDate Ali I, Rashdan I. Hospital physician. 1999 Mar:39.[dermnetnz.org]
  • .: The epidemiology of tropical myositis in the Mengo districts of Uganda. Trans. R. Soc. Trop. Med. Hyg. 72 :46, 1978 PubMed CrossRef Google Scholar 3. Kerrigan, K.R., Nelson, S.J.: Tropical pyomyositis in eastern Ecuador. Trans. R. Soc. Trop. Med.[link.springer.com]
Sex distribution
Age distribution

Pathophysiology

  • This report mainly focuses on nontropical primary pyomyositis because the pathophysiologic features, clinical course, and response to treatment is similar for both.[triggered.clockss.org]

Prevention

  • The efficacy of intranasal mupirocin in the prevention of staphylococcal infections: a review of recent experience. J Hosp Infect 1994 ; 27 : 81 –98.[pmj.bmj.com]
  • The results of the blood cultures were negative, preventing guided antibiotic therapy.[clinmedjournals.org]
  • Courtesy of Centers for Disease Control and Prevention. American trypanosomiasis: The causative organism is a protozoan, Trypanosoma cruzi.[emedicine.medscape.com]
  • Therefore, treatment for at least 8 weeks is suggested to prevent auto-reinfection. Treatment solely with albendazole, without concomitant steroid use, was not associated with adverse reactions from nematode death.[mja.com.au]

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