Abstract A child with truncus arteriosus communis, characterized by the posterior origin of an individualized pulmonary trunk is presented. [ahajournals.org]

Case presentation A 28-year old female with a history of unrepaired TA presented to the Adolescent and Young Adult Congenital Clinic for a second opinion regarding pregnancy counseling. [jcmr-online.biomedcentral.com]

It occurs in 1.5% of cases of congenital heart defects in newborns, presenting variations in their presentation as to the origin of the pulmonary trunk, which in 1949 generated an initial classification by Collett and Edwards 2, followed by Van Praagh [scielo.br]

Adult and Adolescent Management Adult patients with truncus arteriosus may present in two ways. The first is that they are still blue or cyanotic, almost always with very high blood pressures in their lungs. [cincinnatichildrens.org]

In the older, unrepaired infant who has received little or no cardiac care, a higher risk of infections is present if 22q11 deletions are present. Most complications occur post-operatively and usually in the first 48 hours postoperatively. [ncbi.nlm.nih.gov]

• Fatigue

  Symptoms include: Bluish skin (cyanosis) Delayed growth or growth failure Fatigue Lethargy Poor feeding Rapid breathing (tachypnea) Shortness of breath (dyspnea) Widening of the finger tips (clubbing) Surgery is needed to treat this condition. [medlineplus.gov]

  Progressive pulmonary hypertension Leaky heart valves (regurgitation) Heart rhythm disturbances (arrhythmias) Problems related to prior operation Common signs and symptoms of these complications include shortness of breath when exercising, dizziness, fatigue [mayoclinic.org]

• Diastolic Murmur

  […] and a diastolic murmur if truncal valve regurgitation is present. [ncbi.nlm.nih.gov]

• Systolic Murmur

  These infants exhibit poor feeding, lethargy, tachypnea, costal-sternal retractions, grunting, nasal flaring, tachycardia, or hepatomegaly.[2] The cardiac exam will be notable for an ejection click and systolic murmur, single loud second heart sound, [ncbi.nlm.nih.gov]

The first diagnosis of truncus arteriosus in the life of this patient, promoted by our hospital, prompted the hospital's medical staff to deepen invasive workups, even with a history of two previous cardiac catheterizations with a diagnosis of pulmonary [scielo.br]

• Right Bundle Branch Block

  Right bundle branch block and arrhythmias such as supraventricular tachycardia were also noted. [ncbi.nlm.nih.gov]

• Biventricular Hypertrophy

  hypertrophy Cardiomegaly Increased pulmonary vascularity Hypocalcemia (if associated with DiGeorge syndrome) Classification[edit] A well-known classification is the fourfold system developed by Collett and Edwards in 1949.[9] Collett/Edwards Types I, [en.wikipedia.org]

Treatment of Truncus Arteriosus Initial treatment begins with stabilizing the infant. Medications to control congestive heart failure such as diuretics are often begun. [cincinnatichildrens.org]

Into adulthood We will help patients who have had truncus arteriosus treatment transition care to an adult cardiologist. [chop.edu]

Periventricular closure of a perimembranous VSD: treatment option in selected patients. Thorac Cardiovasc Surg. 2012 ;60 (1): 78 – 80. Google Scholar | Medline | ISI 5. Carminati, M, Butera, G, Chessa, M. [journals.sagepub.com]

PMID: 7677508 [Surgical treatment of interrupted aortic arch in infants under three months of age]. Yamaguchi M, Ohashi H, Imai M, Oshima Y, Maeda H, Hosokawa Y, Tsukube T, Tachibana H. Yamaguchi M, et al. [pubmed.ncbi.nlm.nih.gov]

The peripheral pulmonary arteries also may become narrowed and require treatment. [heart.org]

The prognosis of patients with TA lesions is poor without surgical intervention. Newborns often present with signs of florid heart failure and cyanosis. [jcmr-online.biomedcentral.com]

The role of coronary artery abnormalities in the prognosis of truncus arteriosus. J Thorac Cardiovasc Surg. 1992 Dec;104(6):1728-42. [PubMed: 1453739] 7. Martin BJ, Karamlou TB, Tabbutt S. [ncbi.nlm.nih.gov]

Objectives: Identify the etiology of truncus arteriosus. Recall the presentation of an infant with truncus arteriosus. List the treatment and management options available for truncus arteriosus. [ncbi.nlm.nih.gov]

A number of these cases have survived well into adulthood.[14] Epidemiology[edit] Persistent truncus arteriosus is a rare cardiac abnormality that has a prevalence of less than 1%.[3][15] Additional images[edit] See also[edit] Truncus arteriosus (embryology [en.wikipedia.org]

Keith JD: Prevalence, incidence, and epidemiology. Heart Disease in Infancy and Children. 1978, New York: Macmillan, 3 2. [jcmr-online.biomedcentral.com]

This also inhibits the proper creation of separate aortic and pulmonary valves resulting in a single truncal valve.[3] While no direct cause is known, TA is frequently associated with 22q11 genetic mutations.[4] Epidemiology TA is seen with an annual [ncbi.nlm.nih.gov]

To understand the pathophysiology of TA, it is first important to understand the path of blood flow and anatomy. [ncbi.nlm.nih.gov]

[citation needed] Pathophysiology[edit] Anatomical changes associated with this disorder includes:[citation needed] single artery arising from the two ventricles which gives rise to both the aortic and pulmonary vessels abnormal truncal valve right sided [en.wikipedia.org]

What about preventing endocarditis? For patients with uncorrected or partially corrected truncus arteriosus, antibiotics are recommended before certain dental procedures to prevent endocarditis. See the section on Endocarditis for more information. [heart.org]

There is no known prevention. Early treatment can often prevent serious complications. Fraser CD, Kane LC. Congenital heart disease. In: Townsend CM Jr, Beauchamp RD, Evers BM, Mattox KL, eds. [medlineplus.gov]

Prevention In most cases, congenital heart defects such as truncus arteriosus can't be prevented. [mayoclinic.org]

The more leaky (or narrowed) this valve is, the greater the chance that some intervention has to be done sooner than later (on average within five to seven years) to prevent severe damage to the heart. [cincinnatichildrens.org]

Contributed by Centers for Disease Control and Prevention (Public Domain) Figure Truncus arteriosus. Image courtesy O.Chaigasame References 1. Chen Q, Gao H, Hua Z, Yang K, Yan J, Zhang H, Ma K, Zhang S, Qi L, Li S. [ncbi.nlm.nih.gov]