Blue-native gel electrophoresis revealed that TbTim62 is present primarily in ∼150-kDa and also in ∼1100-kDa protein complexes, whereas TbTim17 is present in multiple complexes within the range of ∼300 to ∼1100 kDa. [ncbi.nlm.nih.gov]

The present study demonstrated that T. brucei can infect microglial cells in the human CNS. [omicsonline.org]

They also present a cytosolic localization, a similar pattern of expression and a marked preference for Arg/Lys residues at P1′. [ri.conicet.gov.ar]

• Camping

  […] targets of unknown function, the cAMP response proteins (CARPs), rather than the classical protein kinase A cAMP effector (PKA). [mdpi.com]

  The site where these remnants were found fits the meagre, albeit significant, information presented by Bruce in his writings on the location of the camp. [doi.org]

  Trypanosoma brucei is also able to utilise adenylate cyclases (AdCs), namely T. brucei adenylate cyclase (TbAdC), an enzyme which catalyses the conversion of ATP to cyclic adenosine monophosphate (cAMP). [owlcation.com]

  Intriguing mechanistic insights into how trypanosomes employ cAMP to coopt host pathways and thereby thwart immunity. 116. Oberholzer M, et al. [ncbi.nlm.nih.gov]

  Glycan-induced antilipolysis is blocked by a low Km cAMP phosphodiesterase ihibitor, imazodan, and okadaic acid. [microbewiki.kenyon.edu]

• Neglect

  Abstract Neglected tropical diseases (NTDs) affect over one billion people all over the world. [ncbi.nlm.nih.gov]

• Candida

  Burrack and Judith Berman, Real-Time Evolution of a Subtelomeric Gene Family in Candida albicans, Genetics, 10.1534/genetics.115.177451, 200, 3, (907-919), (2015). [doi.org]

The compound is currently awaiting phase III clinical trials and could lead to a novel oral therapeutic for the treatment of HAT. However, the mode of action of AN5568 in T. brucei is unknown. [ncbi.nlm.nih.gov]

Reliable and validated biomarkers could represent a possible breakthrough in the management of this tumor type, by facilitating diagnosis, refining prognosis and providing guidance towards the choice of the most appropriate therapy In this thesis we approach [avhandlingar.se]

Prognosis African trypanosomiasis is fatal if not treated. [ 15 ] In early or stage 1 disease, most patients recover fully with treatment. [patient.info]

Brigadeiro Trompowski, Rio de Janeiro 21941-590, Brazil Received: 6 February 2018 / Revised: 12 April 2018 / Accepted: 20 April 2018 / Published: 25 April 2018 Trypanosoma brucei, etiological agent of Sleeping Sickness in Africa, is the prototype of African [mdpi.com]

Protozoan parasites within the species Trypanosoma brucei are the etiological agent of human sleeping sickness and Nagana in animals. Infections are limited to patches of sub-Saharan Africa where insects vectors of the Glossina genus are endemic. [sanger.ac.uk]

Here, we have explored the feasibility of using commercially available LAMP kits, designed to detect the Trypanozoon group of trypanosomes, as a xenomonitoring tool to screen tsetse flies for trypanosomes to be used in future epidemiological surveys. [ncbi.nlm.nih.gov]

The epidemiology of Trypanosoma rhodesiense sleeping sickness in Alego location, Central Nyanza, Kenya. Evidence that cattle may act as a reservoir host of trypanosomes infectious to man. [cambridge.org]

The second volume, Antimicrobial Drug Resistance: Clinical and Epidemiological Aspects, is devoted to the clinical aspects of drug resistance. [books.google.it]

Here we report that T. b. gambiense resists TLFs via a hydrophobic β-sheet of the T. b. gambiense-specific glycoprotein (TgsGP), which prevents APOL1 toxicity and induces stiffening of membranes upon interaction with lipids. [ncbi.nlm.nih.gov]

[…] ice crystal formation in one part of a tightly sealed metal tube to prevent crystallization in another part of the same volume. [leica-microsystems.com]