Presentation
The case is reported in view of its rarity, atypical presentation and need to distinguish from meningiomas which they can mimic radiologically. [ncbi.nlm.nih.gov]
NEUROPATHOLOGY FOR MEDICAL STUDENTS Presented by William I. [web.archive.org]
Article / Publication Details First-Page Preview Abstract Three cases of melanotic neuroectodermal tumors of infancy are presented. Two were localized on the midline, involving the skull and extending subdurally. [karger.com]
More than 70% of meningiomas express somatostatin receptors which can be used with radiological imaging, especially when looking for local recurrence. [ 2, 9 ] Presentation Meningiomas present as a space-occupying lesion. [patient.info]
Entire Body System
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Collapse
An MR angiogram was performed on the previous case, with the following sequences: MRA through the level of the middle cerebral arteries, MRA through the level of the petrous segment of the internal carotid arteries, collapsed MRA, and MRA projection. [emedicine.com]
Respiratoric
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Cough
[…] the knee or ankle, with or without shooting pain down the leg) Back pain that gets worse over time, is often in the middle or lower back, is usually severe and not relieved by pain medicine, gets worse when lying down or straining (such as during a cough [medlineplus.gov]
You may experience headaches that: are worse in the morning when waking up occur while you’re sleeping are made worse by coughing, sneezing, or exercise You may also experience: vomiting blurred vision or double vision confusion seizures (especially in [healthline.com]
Unfortunately, the patient later presented with persistent cough and hypoxia: a total body CT scan documented multiple thoracic space occupying lesions, compatible with metastases. [bmccancer.biomedcentral.com]
Musculoskeletal
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Contusion
Imaging showed a small left frontotemporal contusion along with a large right frontoparietal extra axial mass lesion suggestive of a meningioma. Patient improved significantly after craniotomy and tumour decompression. [ncbi.nlm.nih.gov]
Skin
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Hirsutism
[…] symptoms can occur with pituitary tumors: nipple discharge, or galactorrhea lack of menstruation in women development of breast tissue in men, or gynecomastia enlargement of the hands and feet sensitivity to heat or cold increased amounts of body hair, or hirsutism [healthline.com]
Psychiatrical
Neurologic
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Headache
Sphenoid Ridge Eye-bulging, decreased vision, paralysis of eye movement, seizures, memory difficulty, personality change, headache. [braininjury-explanation.com]
These types of posterior fossa meningiomas can cause headaches, seizures, and difficulty walking. [mountsinai.org]
Seek emergency care if you have: Sudden onset of seizures Sudden changes in your vision or memory Make an appointment to see your doctor if you have persistent signs and symptoms that concern you, such as headaches that worsen over time. [mayoclinic.com]
A large meningioma tumor could eventually become cancerous, but even if it remains benign, it can create pressure on the brain, resulting in vision or hearing loss, headaches, seizures or other problems. [abcnews.go.com]
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Agitation
Some of the side effects include indigestion, weight gain, restlessness, agitation and sleep disturbance. Let your doctor or nurse know if these are causing problems or you notice any other effects. [macmillan.org.uk]
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Motor Disturbances
Neuropsychiatric symptoms, bowel and bladder dysfunction, and sensory and motor disturbances. Increasing intracranial pressure 66. Neuroimaging: CT and MRI of melanocytosis and melanomatosis shows diffuse thickening and enhancement of the leptomeninges [slideshare.net]
Workup
If an emergency craniotomy is required, an extensive workup may not be possible. Common Types of Brain Tumors We treat several types of brain tumors at Goodman Campbell. [goodmancampbell.com]
If an emergency craniotomy is required, an extensive workup may not be possible. [tnbrainandspine.com]
[…] cauda equina, or subependymal areas, which extend into the sulci of the cerebrum or folia of the cerebellum MRI of the spinal cord can show nerve-root thickening, cord enlargement, intraparenchymal and subarachnoid nodules, or epidural compression See Workup [emedicine.medscape.com]
Any adult who has a recent onset of seizures, particularly focal seizures, is considered a tumor suspect until adequate neurologic workup proves otherwise. Specific Tumor Types There are many types of tumors that develop intracranially. [dartmouth.edu]
Treatment
Treatment The decision of whether to, and how best to, treat a meningioma is based on multiple factors, including size and location of the tumor, symptoms, growth rate, and age of the patient (among others). [braininjury-explanation.com]
When clinical trials show that a new treatment is better than the standard treatment, the new treatment may become the standard treatment. Patients may want to think about taking part in a clinical trial. [web.archive.org]
The recurrence of intracranial meningiomas after surgical treatment. J Neurol Neurosurg Psychiatry 1957; 20 (1) 22-39 50 McWhirter R, Pennybacker J, et al. Radiation treatment of cerebral tumours. [doi.org]
Because most meningiomas grow slowly, often without any significant signs and symptoms, they do not always require immediate treatment and may be monitored over time. [mayoclinic.com]
Prognosis
More novel molecular targets are being researched. [ 18, 19 ] Prognosis Atypical and anaplastic types of meningiomas can rarely metastasise. Completely resected meningiomas usually have an excellent prognosis. [patient.info]
Prognosis A prognosis is an estimate of the likely progress of a disease after a diagnosis, based on an average patient group. [braintumour.ca]
In adults, the age that a person is diagnosed with meningioma is one of the best ways to predict prognosis. In general, the younger the adult, the better the prognosis. Extent of tumor residual. Resection is surgery to remove a tumor. [cancer.net]
What is the prognosis of meningiomas? For tumours treated by surgery, the prognosis (likely outcome of treatment) depends primarily on the extent of the surgical resection, which is largely determined by the location of the tumour. [uhs.nhs.uk]
Certain factors affect prognosis (chance of recovery) and treatment options. The prognosis (chance of recovery) and treatment options for primary brain and spinal cord tumors depend on the following: The type and grade of the tumor. [my.clevelandclinic.org]
Etiology
The etiology of meningioma is largely unknown, and exposure to high-dose ionizing radiation and coexistence with certain rare genetic conditions explain only a small fraction of the incidence of the disease. [doi.org]
Epidemiology
The epidemiology study results were heterogeneous, with sparse data on long‐term use ( 10 years). [doi.org]
Pathophysiology
Pathophysiology The brain and spinal cord tissue are very delicate and are protected within the bony cavities of the skull (cranium) and vertebral column (spinal canal) respectively. [healthhype.com]
The authors review the pathophysiology, presentation, and treatment of this tumor, including new prognostic indicators in atypical and malignant meningiomas. [medlink.com]
Pathophysiology Meningiomas may occur intracranially or within the spinal canal. They are thought to arise from arachnoidal cap cells, which reside in the arachnoid layer covering the surface of the brain. See the images below. [emedicine.com]
Metabolomics is defined as “the quantitative measurement of the multiparametric metabolic response of living systems to pathophysiological stimuli or genetic modification” ( 9 ). [doi.org]
Prevention
Strength of the Evidence for a Cancer-Preventive Effect of the Absence of Excess Body Fatness, According to Cancer Site or Type. [doi.org]
"These findings should not prevent anyone from going to the dentist," says lead researcher and neurosurgeon Elizabeth B. Claus, MD, PhD, of Yale University School of Medicine and Boston's Brigham and Women's Hospital. [web.archive.org]
Depending on the areas of the brain and/or spinal cord that are involved, radiation therapy may help shrink any remaining tumor and can also prevent it from spreading to the tissues around it. [columbianeurology.org]
There are medications under investigation that may be helpful in preventing neurocognitive effects from radiation. [targetingcancer.com.au]