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Umbilical Sepsis


Presentation

  • We present a rare presentation of neonatal herpes in an 8 day old neonate who presented with fever and pustules around the umbilicus. Baby was treated with intravenous benzylpenicillin and flucloxacillin.[adc.bmj.com]
  • It normally disappears between the fifth and ninth weeks of intrauterine life .A patient with PVID (patent vitello-intestinal duc) may present with umbilical sepsis.[scopemed.org]
  • DOI: Umbilical pilonidal cyst presenting as umbilical sepsis Abstract Pilonidal disease comprises a spectrum of clinical presentations, ranging from asymptomatic hair containing cysts and sinuses to large symptomatic abscesses that have some tendency[ijmedicine.com]
  • Superbly presented with line drawings, high quality radiographic images and colour photographs. Presented in similar form to its sister textbook Davidson’s Principles and Practice of Medicine.[books.google.es]
Persistent Vomiting
  • vomiting (last three feeds)/refusal to feed/inability to suck/weak suck), altered mentation (lethargic/unconsciousness/convulsions) or skin changes (deep jaundice/ periumbilical redness) 29.[f1000research.com]
Hypertrophic Pyloric Stenosis
  • Pyloric Stenosis 361 Gastrostomy and Jejunostomy 369 Duodenal Obstruction 383 Intestinal Malrotation 392 JejunoIleal Atresia 405 Meconium Ileus 415 Duplications of the Alimentary Tract 423 Necrotizing Enterocolitis 434 Constipation 445 Hirschsprungs[books.google.es]
Purpura
  • […] symptoms (e.g. body temperature inestability, hypotension, poor perfusion with pallor, tachycardia or bradycardia, apnoea, respiratory distress, grunting, cyanosis, irritability, lethargy, seizures, refusal to feed, abdominal distension, petechial, purpura[journals.plos.org]
Indecisiveness
  • Diagnostic indecision leads to increased morbidity due to delayed treatment and overuse of empiric broad-spectrum antibiotics 5.[biorxiv.org]
Vaginal Bleeding
  • Multiple pregnancies, structural/chromosomal anomalies and patients with clinical signs of chorioamnionitis or vaginal bleeding at admission were not considered eligible for this study.[journals.plos.org]

Workup

  • Currently the baseline workup is done using blood samples from the infant to perform Blood culture, CBC, I/T ratio. These tests have shown to have low sensitivity and specificity to diagnosis EONS.[clinicaltrials.gov]
  • We studied 50 LBW (Low birth weight) neonates born from mothers with PROM as the case group and fifty LBW neonates born from mothers without PROM as our control group Neonates born from pregnant women with PROM underwent sepsis workup and blood samples[scialert.net]
Mediastinal Mass
  • Child Abuse 213 Head and Neck 221 Choanal Atresia 223 Thyreoglossal and Branchial Cysts Sinuses and Fistulas 228 Tracheostomy 235 Chest 245 Chest Wall Deformities 247 Breast Disorders in Children and Adolescents 257 Congenital Airway Malformations 262 Mediastinal[books.google.es]
Bordetella Pertussis
  • pertussis and other bordetella sp infections; herpes simplex; toxoplasmosis; pneumocystis and other less common fungal infections; and healthcare-associated infections in the nursery Keep up with the most relevant topics in fetal/neonatal infectious[books.google.es]
White Matter Lesions
  • Yoon BH, Romero R, Yang SH, Jun JK, Kim IO, et al. (1996) Interleukin-6 concentrations in umbilical cord plasma are elevated in neonates with white matter lesions associated with periventricular leukomalacia. Am J Obstet Gynecol May 174(5): 1433–40.[journals.plos.org]

Treatment

  • Due to the risk of peritoneal extension of inflammation from this lesion, conservative treatment is not acceptable. Surgery is the choice of treatment. Keywords Umbilicus, Pilonidal cyst, Sepsis, Hairy References Azzam S, Al-Kadi.[ijmedicine.com]
  • Early detection and treatment, has been shown to decrease the mortality significantly. We present a rare presentation of neonatal herpes in an 8 day old neonate who presented with fever and pustules around the umbilicus.[adc.bmj.com]
  • Due to the risk of peritoneal extension of inflammation from this lesion, conservative treatment is not acceptable. Surgery is the choice of treatment. Key words: Umbilicus, Pilonidal cyst, Sepsis, Hairy[scopemed.org]
  • Form a definitive diagnosis and create the best treatment plans possible using evidence-based recommendations and expert guidance from world authorities.[books.google.es]

Prognosis

  • Prognosis The prognosis for most infants is variable. • In most cases prognosis is Poor. • Omphalitis with complications is associated with mortality rate up to 80% in developed countries. • In the less developed countries, mortality is 95% 17.[slideshare.net]
  • Prognosis The prognosis for foals with neonatal sepsis is fair to poor with more than 50% of these foals not surviving.[vetspecialists.com]
  • Prognosis The prognosis for infants with omphalitis varies. Outcome is usually favorable in infants with uncomplicated omphalitis associated with cellulitis of the anterior abdominal wall.[emedicine.medscape.com]
  • Neonatal atrial flutter: significant early morbidity and excellent long-term prognosis. Am Heart J, 133 (1997), pp. 302-306 Copyright 2015. Sociedade de Pediatria de São Paulo[elsevier.es]

Etiology

  • The etiology and treatment of the pilonidal sinus. Dig Surg. 1995;12:117-20. Ali C, Hakan B, Omer FA, Abdullah O. Etiological factors in umbilical pilonidal sinus. Indian J Surg. 2011;73:54-7. Eryilmaz R, Sahin M, Okan I.[ijmedicine.com]
  • Conclusion: UCBC has good diagnostic validity for etiological diagnosis of bacterial sepsis in high risk neonates. Organisms grown in umbilical cord blood samples are comparable with venous blood culture samples.[medicalsciencejournal.com]
  • Cord pus swabs were taken on these to determine the bacterial etiology for cord sepsis and the neonates were then followed up for a maximum of ten days to determine the immediate outcome.[makir.mak.ac.ug]
  • Etiology Omphalitis is a polymicrobial infection typically caused by a mixture of aerobic and anaerobic organisms.[emedicine.medscape.com]

Epidemiology

  • The text gives a global emphasis on epidemiological and cultural issues such as problems associated with directed transfusion of blood products from first degree relatives, the issues of informed consent and patient autonomy.[books.google.es]
  • Hospital-acquired infections in the NICU: epidemiology for the new millennium. Clin Perinatol 2008; 35: 223–249. Kumar M, Paul VK, Kapoor SK, Anand K, Deoraria AK. Neonatal outcomes at a subdistrict hospital in north India.[jemds.com]
  • Infections acquired in the nursery: epidemiology and control. En: Remington JS, Klein JO, editores. Infectious diseases of the fetus and newborn infant. Fifth edition. Philadelphia: Saunders; 2001. p. 1264-83. 10.[revistas.uis.edu.co]
Sex distribution
Age distribution

Pathophysiology

  • This article outlines the pathophysiology, differential diagnosis, microscopic features and management of this rare disease. Due to the risk of peritoneal extension of inflammation from this lesion, conservative treatment is not acceptable.[scopemed.org]
  • Kunio Okuda, Jean-Pierre Benhamou Springer Science & Business Media, ٠٩‏/١١‏/٢٠١٣ - 569 من الصفحات Portal hypertension is the abnormal pathophysiologic state that develops in liver cirrhosis and certain other disorders with characteristic clinical and[books.google.com]
  • […] s career goals to: 1) lead a clinical-translational research program on the pathophysiology and host responses of perinatal infection and 2) bring new, reliable sepsis diagnostics to clinical practice, to improve neonatal outcomes through targeted treatment[grantome.com]

Prevention

  • Prevention of sepsis is probably the best management strategy as far as neonatal sepsis is concerned. Strategies include prevention of early-onset sepsis and prevention of late-onset sepsis.[books.google.es]
  • Most of newborn infections can be prevented by following some simple rules of cleanliness and hygiene.[prernanayak.blogspot.com]
  • Endoscopic sclerotherapy and beta-blockers have come to be widely used in the man agement and prevention of variceal bleeding.[books.google.com]

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