Presentation
Presented with midline ulcerated mass. Diagnosis: Squamous cell carcinoma, arising actinic cheilitis 64 year old male with a long history of cigarette smoking presents with an a symetrical nodular mass in the retromolar region. [oralcancerfoundation.org]
At the present time, surgery associated or not with post-operative radiotherapy seems to be optimal curative treatment. The question of whether neck dissection should be performed remains debated for patients without clinically nodes. [ncbi.nlm.nih.gov]
Updated, reorganized, and revised throughout, this highly lauded three-volume reference provides an interdisciplinary approach to the diagnosis, treatment, and management of head and neck diseases, including the incidence, etiology, clinical presentation [books.google.com]
Advertisements present are clearly labelled and in no way support the website or influence the contents. [fauquierent.net]
Potentially malignant disorders of the oral and oropharyngeal mucosa; terminology, classification and present concepts of management. Oral Oncology 45 (2009) 317–323. Medline. [dermnetnz.org]
Entire Body System
- Asymptomatic
Diagnosis: Aspirin Burn A 31 year old female noticed a flat grey/black asymptomatic alteration in the anterior floor of her mouth, of unknown duration. [oralcancerfoundation.org]
This form is usually asymptomatic. 2. [dermnetnz.org]
Most oral cancers are asymptomatic to begin with, meaning they don't give you any pain or altered feelings- these only come much later on. [jamiethedentist.com]
Premalignant lesions and early cancers are usually asymptomatic (ie the patient has no pain and they don’t even know they have a lesion), so their detection is contingent upon a careful soft tissue examination by a dentist. [maaom.memberclicks.net]
Two of the three patients were asymptomatic. One had tenderness on palpation. [northshore.org]
Respiratoric
- Hoarseness
Signs and Symptoms Diagnosis Treatment Symptoms may include: Reddish patches, called erythroplasia Whitish patches, called leukoplakia A sore that does not heal and bleeds easily A lump or thickening of the tissues Chronic sore throat or hoarseness Difficulty [ucsfhealth.org]
Some patients complain of numbness in the tongue or other areas of the mouth, while others experience persistent hoarseness. [livestrong.com]
Hoarseness or a change in the voice can be the first sign of cancer of the voice box. [livescience.com]
[…] a lump in the neck loose teeth, or dentures that no longer fit earache, or ringing in the ears Pharyngeal cancer throat pain or difficulty swallowing a persistent sore throat or cough coughing up bloody phlegm bad breath weight loss voice changes or hoarseness [cancervic.org.au]
You may get some mouth ulcers and your voice may become hoarse. You might find that your sense of taste and smell changes. Eating food can become difficult and swallowing can be painful. Your doctor can prescribe medicines to help. [macmillan.org.uk]
Jaw & Teeth
- Bleeding Gums
Unexplained bleeding. See- Bleeding gums for a range of common explanations for blood in the mouth. Nerve changes. Changes in the feelings of your nerves that supply your lower lip or tongue. [jamiethedentist.com]
Adverse effects of radiation therapy in the mouth include: tooth decay mouth sores bleeding gums jaw stiffness fatigue skin reactions, as with a burn Chemotherapy Chemotherapy, radiotherapy, and surgery are three treatment options. [medicalnewstoday.com]
It can also be associated with a white patch, loose teeth, bleeding gums, persistent ear ache, a feeling of numbness in the lip and chin or swelling. [16] In the case of pharyngeal cancer there can also be difficulty or painful swallowing, and an altered [en.wikipedia.org]
- Poor Oral Hygiene
Others include poor oral hygiene, irritation caused by ill-fitting dentures, rough surfaces on teeth and poor nutrition. [ucsfhealth.org]
Lydiatt, MD, director of head and neck cancer surgery at the University of Nebraska Medical Center, "Poor oral hygiene over a long period of time, 30 or 40 years, can be a cause oral cancer. This is because of chronic inflammation. [everydayhealth.com]
- Sore Mouth
Symptoms of mouth cancer Symptoms of mouth cancer include: sore mouth ulcers that don't heal within several weeks unexplained, persistent lumps in the mouth that don't go away unexplained, persistent lumps in the neck that don't go away unexplained looseness [nhs.uk]
[…] due to a sore mouth, which may make eating difficult Inability to wear dentures for a period of time Depending on the type of treatment, other side effects may include: Fatigue Dental problems lowered immune system Nausea Vomiting Mouth sores Lack of [hopkinsmedicine.org]
- Loose Tooth
It started with a tooth that just fell out and another one a month later. I had no pain – they just popped out. In August, when the third one became loose, I called an oral surgeon. He pulled the loose tooth and biopsied the tissue. [sixstepscreening.org]
- Tooth Loss
Lung cancer — Several investigators examined the relationship between lung cancer and tooth loss or periodontal disease. [perioimplantadvisory.com]
Musculoskeletal
- Neck Pain
Swelling in the jaw, neck, or side of the face. This may cause dentures to fit poorly. Frequent sinus infections that do not respond to antibiotics. Neck pain that won't go away. Frequent headaches. Pain in the upper teeth. [my.clevelandclinic.org]
[…] persistent sore throat or cough coughing up bloody phlegm bad breath weight loss voice changes or hoarseness dull pain around the breastbone a lump in the neck pain in the ear or frequent ear infections feeling that your air supply is blocked numbness [cancervic.org.au]
Symptoms may include: A lip or mouth sore that does not heal A white or red patch on the gums, tongue, or lining of mouth A lump on the lip or in the mouth or throat Unusual bleeding, pain, or numbness in the mouth area Swelling of the jaw or neck Pain [hopkinsmedicine.org]
When on the lips, it commonly looks like a persistent crusting ulcer that does not heal, and slowly grows. [4] Other symptoms may include difficult or painful swallowing, new lumps or bumps in the neck, a swelling in the mouth, or a feeling of numbness [en.wikipedia.org]
Psychiatrical
- Fear
I was sick with fear - if I survived it, what would I end up looking like? My nightmare had begun innocuously enough. Eighteen months earlier I’d been brushing my teeth when I first felt the tiny painless lump on my gum. [dailymail.co.uk]
But the fear of it returning is constant. I cannot stress the importance of good medical practitioners, screenings at ever dental visit, and awareness raising. [sixstepscreening.org]
Treatment
This way people can get the best treatment available now and may also get the new treatments that are thought to be even better. [cancer.org]
What are the treatment options for mouth cancer? Mouth cancer treatments which may be considered include radiotherapy, surgery and chemotherapy. [patient.info]
PURPOSE: The aim of this retrospective study was to determine a rational of treatment of squamous-cell carcinoma of the upper gum and hard palate. [ncbi.nlm.nih.gov]
Treatment of mouth cancer What treatment you’re offered will depend on what type of mouth cancer you have, where it is and how far it’s spread. Your doctor will discuss your treatment options with you. [bupa.co.uk]
Many centres have reported excellent cure and local control rates for their chosen treatment method. Electron beam treatment is recognized as a method of treatment and has theoretical advantages related to its depth-dose characteristics. [aboutcancer.com]
Prognosis
The 5-year survival rate was 33.7%; patients without node involvement had better prognosis (p=0.034). The 5-year rate of recurrence-free survival was 61%; patients without node involvement had better prognosis (p = 0.032). [ncbi.nlm.nih.gov]
Survival Rate Duodenal Cancer – Symptoms, Prognosis, Survival Rate and Treatment Vaginal Cancer – Symptoms, Signs, Pictures, Treatment, Causes Tonsil Cancer – Pictures, Symptoms, Survival Rate, Staging, Prognosis Fallopian Tube Cancer – Symptoms, Prognosis [cancerwall.com]
[…] this highly lauded three-volume reference provides an interdisciplinary approach to the diagnosis, treatment, and management of head and neck diseases, including the incidence, etiology, clinical presentation, pathology, differential diagnosis, and prognosis [books.google.com]
According to 2009 data from the Centers for Disease Control and Prevention, the five 5-year survival rate is 50 percent, but detecting the disease early improves the patient's prognosis. [livestrong.com]
Large bulky tumors or high-grade tumors carry a poorer prognosis and may best be treated by surgical resection combined with postoperative radiation therapy.[ 15 ] The prognosis also depends on the following:[ 16, 17 ] Gland in which they arise. [northshore.org]
Etiology
Updated, reorganized, and revised throughout, this highly lauded three-volume reference provides an interdisciplinary approach to the diagnosis, treatment, and management of head and neck diseases, including the incidence, etiology, clinical presentation [books.google.com]
Certain HPV strains are etiologic risk factors for Oropharyngeal Squamous Cell Carcinoma (OSCC) It is important to note that over 25% of all oral cancers occur in people who do not smoke and who only drink alcohol occasionally. [webmd.com]
It is a lesion of unknown etiology that actually moves around the mouth over time. [capedental.com]
There is concern about an ongoing increase in younger patients and in women in particular, as well as in the oropharynx, possible due to human papillomavirus (HPV) infection. [4] The etiology of OSCC appears to be multifactorial and strongly related to [emedicine.medscape.com]
[…] cancers.[ 1, 2 ] Most patients with malignant salivary gland tumors are in their sixth or seventh decade of life.[ 3, 4 ] Carcinogenesis and Risk Factors Although exposure to ionizing radiation has been implicated as a cause of salivary gland cancer, the etiology [northshore.org]
Epidemiology
European Journal of Epidemiology 2005; 20:229-236. [perioimplantadvisory.com]
"Epidemiology of oral cancer in Arab countries". Saudi Medical Journal. 37 (3): 249–55. doi : 10.15537/smj.2016.3.11388. PMC 4800887. [en.wikipedia.org]
Human papillomavirus and the epidemiology of head and neck cancer. In: Flint PW, Haughey BH, Lund V, et al, eds. Cummings Otolaryngology: Head and Neck Surgery. 6th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 75. [medlineplus.gov]
National Cancer Institute, Surveillance, Epidemiology and End Result Program. Available at https://seer.cancer.gov/statfacts/html/oralcav.html. Accessed: May 20, 2017. Nagler R, Dayan D. The dual role of saliva in oral carcinogenesis. [emedicine.medscape.com]
Surveillance, Epidemiology, and End Results Program public-use data. Rockville, MD: 1973-1998. National Cancer Institute, Division of Cancer Control and Population Sciences, Surveillance Research Program, Cancer Statistics Branch. [dentistryiq.com]
Pathophysiology
Pathophysiology In oral squamous cell carcinoma (OSCC), modern DNA technology, especially allelic imbalance (loss of heterozygosity) studies, have identified chromosomal changes suggestive of the involvement of tumor suppressor genes (TSGs), particularly [emedicine.medscape.com]
Pathophysiology [ edit ] Oral squamous cell carcinoma is the end product of an unregulated proliferation of mucous basal cells. [en.wikipedia.org]
Prevention
These startling statistics from the Centers from Disease Control and Prevention tell a warning tale, but there is some good news, too. If caught early, oral cancer is highly treatable. [consumer.healthday.com]
Preventing mouth cancer The three most effective ways of preventing mouth cancer developing, or preventing it coming back after successful treatment, are: not smoking ensuring you don't drink more than the recommended weekly limits for alcohol eating [nhs.uk]
These cancers are very treatable if caught early, and are easily preventable. The most common causes of head and neck cancer are tobacco and alcohol use. [my.clevelandclinic.org]
They have been shown to prevent most oral HPV infections. It is not clear yet whether they also are able to prevent oral cancers. [medlineplus.gov]
Although gum disease is the more common of the two – affecting slightly more than 47 percent of all adults, according to the Centers for Disease Control and Prevention (CDC) – oral cancer is also a legitimate possibility. [colgate.com]