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Upper Gingival Carcinoma

Gum Neoplasm Malignant Carcinoma of Upper Gum


Presentation

  • At the present time, surgery associated or not with post-operative radiotherapy seems to be optimal curative treatment. The question of whether neck dissection should be performed remains debated for patients without clinically nodes.[ncbi.nlm.nih.gov]
  • Updated, reorganized, and revised throughout, this highly lauded three-volume reference provides an interdisciplinary approach to the diagnosis, treatment, and management of head and neck diseases, including the incidence, etiology, clinical presentation[books.google.com]
  • Presented with midline ulcerated mass. Diagnosis: Squamous cell carcinoma, arising actinic cheilitis 64 year old male with a long history of cigarette smoking presents with an a symetrical nodular mass in the retromolar region.[oralcancerfoundation.org]
  • Advertisements present are clearly labelled and in no way support the website or influence the contents.[fauquierent.net]
  • Potentially malignant disorders of the oral and oropharyngeal mucosa; terminology, classification and present concepts of management. Oral Oncology 45 (2009) 317–323. Medline.[dermnetnz.org]
Poor Oral Hygiene
  • Others include poor oral hygiene, irritation caused by ill-fitting dentures, rough surfaces on teeth and poor nutrition.[ucsfhealth.org]
  • Lydiatt, MD, director of head and neck cancer surgery at the University of Nebraska Medical Center, "Poor oral hygiene over a long period of time, 30 or 40 years, can be a cause oral cancer. This is because of chronic inflammation.[everydayhealth.com]
Sore Mouth
  • Symptoms of mouth cancer Symptoms of mouth cancer include: sore mouth ulcers that don't heal within several weeks unexplained, persistent lumps in the mouth that don't go away unexplained, persistent lumps in the neck that don't go away unexplained looseness[nhs.uk]
  • […] due to a sore mouth, which may make eating difficult Inability to wear dentures for a period of time Depending on the type of treatment, other side effects may include: Fatigue Dental problems lowered immune system Nausea Vomiting Mouth sores Lack of[hopkinsmedicine.org]
Chewing Problem
  • problems Mouth sores that may bleed Pain with swallowing Speech difficulties Swallowing difficulty Swollen lymph nodes in the neck Tongue problems Weight loss Difficulty opening the mouth Numbness and loosening of teeth Bad breath Your doctor or dentist[medlineplus.gov]
Xanthoma
  • […] small, round bump that often has an ulcerated surface Rhabdomyoma A striated-muscle tumor that may appear on the tongue, pharynx, uterus, vagina, or heart Schwannoma A single tumor that grows in the neurilemma (Schwann's sheath) of nerves Verruciform xanthoma[hopkinsmedicine.org]

Treatment

  • PURPOSE: The aim of this retrospective study was to determine a rational of treatment of squamous-cell carcinoma of the upper gum and hard palate.[ncbi.nlm.nih.gov]
  • Updated, reorganized, and revised throughout, this highly lauded three-volume reference provides an interdisciplinary approach to the diagnosis, treatment, and management of head and neck diseases, including the incidence, etiology, clinical presentation[books.google.com]
  • This way people can get the best treatment available now and may also get the new treatments that are thought to be even better.[cancer.org]
  • What are the treatment options for mouth cancer? Mouth cancer treatments which may be considered include radiotherapy, surgery and chemotherapy.[patient.info]
  • Treatment of mouth cancer What treatment you’re offered will depend on what type of mouth cancer you have, where it is and how far it’s spread. Your doctor will discuss your treatment options with you.[bupa.co.uk]

Prognosis

  • The 5-year survival rate was 33.7%; patients without node involvement had better prognosis (p 0.034). The 5-year rate of recurrence-free survival was 61%; patients without node involvement had better prognosis (p 0.032).[ncbi.nlm.nih.gov]
  • […] this highly lauded three-volume reference provides an interdisciplinary approach to the diagnosis, treatment, and management of head and neck diseases, including the incidence, etiology, clinical presentation, pathology, differential diagnosis, and prognosis[books.google.com]
  • , Survival Rate Duodenal Cancer – Symptoms, Prognosis, Survival Rate and Treatment Vaginal Cancer – Symptoms, Signs, Pictures, Treatment, Causes Tonsil Cancer – Pictures, Symptoms, Survival Rate, Staging, Prognosis Fallopian Tube Cancer – Symptoms, Prognosis[cancerwall.com]
  • According to 2009 data from the Centers for Disease Control and Prevention, the five 5-year survival rate is 50 percent, but detecting the disease early improves the patient's prognosis.[livestrong.com]
  • Large bulky tumors or high-grade tumors carry a poorer prognosis and may best be treated by surgical resection combined with postoperative radiation therapy.[ 15 ] The prognosis also depends on the following:[ 16 , 17 ] Gland in which they arise.[northshore.org]

Etiology

  • Updated, reorganized, and revised throughout, this highly lauded three-volume reference provides an interdisciplinary approach to the diagnosis, treatment, and management of head and neck diseases, including the incidence, etiology, clinical presentation[books.google.com]
  • Certain HPV strains are etiologic risk factors for Oropharyngeal Squamous Cell Carcinoma (OSCC) It is important to note that over 25% of all oral cancers occur in people who do not smoke and who only drink alcohol occasionally.[webmd.com]
  • It is a lesion of unknown etiology that actually moves around the mouth over time.[capedental.com]
  • There is concern about an ongoing increase in younger patients and in women in particular, as well as in the oropharynx, possible due to human papillomavirus (HPV) infection. [4] The etiology of OSCC appears to be multifactorial and strongly related to[emedicine.medscape.com]
  • .[ 1 , 2 ] Most patients with malignant salivary gland tumors are in their sixth or seventh decade of life.[ 3 , 4 ] Carcinogenesis and Risk Factors Although exposure to ionizing radiation has been implicated as a cause of salivary gland cancer, the etiology[northshore.org]

Epidemiology

  • "Epidemiology of oral cancer in Arab countries". Saudi Medical Journal. 37 (3): 249–55. doi : 10.15537/smj.2016.3.11388. PMC 4800887.[en.wikipedia.org]
  • European Journal of Epidemiology 2005; 20:229-236.[perioimplantadvisory.com]
  • Human papillomavirus and the epidemiology of head and neck cancer. In: Flint PW, Haughey BH, Lund V, et al, eds. Cummings Otolaryngology: Head and Neck Surgery. 6th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 75.[medlineplus.gov]
  • National Cancer Institute, Surveillance, Epidemiology and End Result Program. Available at . Accessed: May 20, 2017. Nagler R, Dayan D. The dual role of saliva in oral carcinogenesis. Oncology. 2006. 71(1-2):10-7. [Medline].[emedicine.medscape.com]
  • Surveillance, Epidemiology, and End Results Program public-use data. Rockville, MD: 1973-1998. National Cancer Institute, Division of Cancer Control and Population Sciences, Surveillance Research Program, Cancer Statistics Branch.[dentistryiq.com]
Sex distribution
Age distribution

Pathophysiology

  • Pathophysiology In oral squamous cell carcinoma (OSCC), modern DNA technology, especially allelic imbalance (loss of heterozygosity) studies, have identified chromosomal changes suggestive of the involvement of tumor suppressor genes (TSGs), particularly[emedicine.medscape.com]

Prevention

  • These startling statistics from the Centers from Disease Control and Prevention tell a warning tale, but there is some good news, too. If caught early, oral cancer is highly treatable.[consumer.healthday.com]
  • These cancers are very treatable if caught early, and are easily preventable. The most common causes of head and neck cancer are tobacco and alcohol use.[my.clevelandclinic.org]
  • Preventing mouth cancer The three most effective ways of preventing mouth cancer developing, or preventing it coming back after successful treatment, are: not smoking ensuring you don't drink more than the recommended weekly limits for alcohol eating[nhs.uk]
  • Asian Pacific Journal of Cancer Prevention. Asian Pacific Organization for Cancer Prevention. 14 (10): 5567–5577. doi : 10.7314/apjcp.2013.14.10.5567. ISSN 1513-7368.[en.wikipedia.org]
  • They have been shown to prevent most oral HPV infections. It is not clear yet whether they also are able to prevent oral cancers.[medlineplus.gov]

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