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Upper Urinary Tract Infection
Urinary Tract Infection Upper

Presentation

Abstract Angiotensin converting enzyme (ACE) is present within the brush border of the tubular cell of the kidney. [ncbi.nlm.nih.gov]

If urinary tract infections seem to be recurring, it may be time to look at the overall health of your pet to assess any other issues that may be present. [vetmed.tennessee.edu]

Patients present with suprapubic pain, dysuria, urinary urgency and frequency. [amboss.com]

Characteristics/Clinical Presentation When a patient presents with both clinical features and laboratory evidence of a urinary infection, a symptomatic UTI diagnosis can be made. [physio-pedia.com]

Entire Body System

  • Candidiasis

    Detection of renal Candida casts may be a useful diagnostic marker in distinguishing upper versus lower urinary tract candidiasis. [ncbi.nlm.nih.gov]

    "Clinical Practice Guideline for the Management of Candidiasis: 2016 Update by the Infectious Diseases Society of America". Clinical Infectious Diseases. 62 (4): e1–50. doi:10.1093/cid/civ933. PMC 4725385. [en.wikipedia.org]

    I will never understand why don�t doctors tell us or investigate more on the subject of candidiasis. Two of my friends, one of them a naturopath had recommended that I try your program. [es.slideshare.net]

    The fungus Candida is the organism most likely to cause urinary tract yeast infections (candidiasis). Candida frequently infects people who have an impaired immune system or a bladder catheter in place. [msdmanuals.com]

    Oral leukokeratosis occurs early, may possibly cause feeding difficulties and should be distinguished from oral candidiasis in infants. [orpha.net]

  • Infertility

    […] premature delivery, postpartum infections, clinically apparent and subclinical pelvic inflammatory disease, [as well as] postsurgical complications (after abortion, hysterectomy, caesarian section), increased vulnerability to HIV infection and, possibly, infertility [en.wikipedia.org]

    Antimicrobials are not needed for asymptomatic patients who have evidence of inflammation on biopsy specimens or in secretions (category IV prostatitis); however, antimicrobials should be considered for men who are infertile who have bacteria or inflammation [emedicine.medscape.com]

    Another example is seminal fluid inflammation noted during evaluation from an infertile couple. The long-term consequences of such asymptomatic inflammation are unknown. [ncbi.nlm.nih.gov]

  • Constitutional Symptom

    Nephrolithiasis (Kidney Stones) Trauma Genitourinary Tuberculosis Genitourinary Neoplasm Intra-abdominal Abscess Yeast Infection Variation in symptom presentation: Post-menopausal women present with constitutional symptoms, such as abdominal pain, back [physio-pedia.com]

    Pyelonephritis (inflammation of the renal parenchyma) is a clinical syndrome characterized by chills and fever, flank pain and constitutional symptoms caused by bacterial invasion of the kidney. [ncbi.nlm.nih.gov]

  • Recurrent Inflammation

    Lower urinary tract infection Inflammation of the bladder wall Inflammation of the urethra. This usually occurs in an otherwise normal urinary tract and involves only the bladder. This UTI has underlying conditions or special circumstances. [quizlet.com]

Urogenital

  • Urinary Incontinence

    Overactive Bladder in Children (Child Incontinence): Signs, Causes, and Treatment. [online] Available at: http://www.WebMD.com/urinary-incontinence-oab/overactive-bladder-in-children [Accessed 6 Apr. 2015]. Other urinary incontinence causes [depend.com.au]

    It is commonly divided into 'uncomplicated' and 'complicated' infections. painful urination strangury bloody, dark, cloudy urine urinary frequency urinary incontinence urinary urgency systemic symptoms: fevers, chills, rigors, tiredness, confusion UTIs [radiopaedia.org]

    The most prominent symptoms are voiding, such as dysuria, frequency, urgency and urinary incontinence. 11 • Upper UTI or acute pyelonephritis (APN) Infections that reach and inflame the upper urinary tract (ureter, collecting system, renal parenchyma) [guiasalud.es]

    […] cloudy, bloody or bad-smelling urine lower abdominal pain urinary incontinence – the involuntary leakage of urine mild fever (a high temperature between 37–38°C or 98.6–101.0°F) delirium/acute confusion (sudden onset confusion developing within one to [alzheimers.org.uk]

    Elderly women may present with only urinary incontinence and no other symptoms. Urine dipstick test showing positive nitrites or leukocyte esterase are suggestive of UTI, raising the pretest probability by 25%. [pathophys.org]

  • Foul Smelling Urine

    foul-smelling urine, vaginal discharge if female and enlarged prostate(males/bladder What are the factors that predispose to a UTI ? BBCS Very Shit: 1. Being female and pregnancy/menopause, 2. Bladder outlet obstruction (TCC and BPH), 3. [brainscape.com]

    Symptoms Of A Urinary Tract Infection Symptoms of a lower UTI include Frequency and/ or urgency Pain or discomfort when urinating (usually a burning sensation) The feeling of being unable to empty your bladder fully Cloudy and/or foul-smelling urine that [bladderandbowel.org]

    Common UTI symptoms A need to urinate urgently and frequently with small amount of urine voided A sensation of pain or burning with urination Blood in the urine Cloudy or foul smelling urine Cramps or tenderness over the bladder Kidney infections, also [uihc.org]

    Common UTI symptoms include: Generally feeling tired and unwell Cloudy or foul smelling urine Increased need to urinate Pain or burning sensation when urinating Blood in your urine Lower abdominal pain In older men, generalised symptoms such as confusion [netdoctor.co.uk]

  • Urinary Retention

    […] or more times per night to void complaint of loss of urine during sleep Clinical manifestations related to bladder emptying weak stream, hesitance, intermittancy, post-void dribbling, dysuria, urinary retention, difficulty voiding, pain on urination Symptoms [quizlet.com]

    When risk factors for urosepsis are present, such as fever or urinary retention, the patient should be hospitalized and IV antibiotics should be started. [emedicine.medscape.com]

    If urinary obstruction, establish flow (e.g., place a Foley in a patient with urinary retention and UTI). [infectiousdiseaseadvisor.com]

    The diagnostic term for this is urinary retention, and it can be described like overflow from a full cup — the bladder remains full despite some urine trickling out. [womenshealthnetwork.com]

    If acute urinary retention develops, drainage should be by supra-public needle aspiration or if prolonged bladder drainage is required by a suprapubic cystostomy tube. [ncbi.nlm.nih.gov]

  • Enlargement of the Prostate

    In men, physical examination is important for detecting possible infection of the genitals and enlargement of the prostate gland, which may be a sign of serious disease. [britannica.com]

    In men, an enlarged or inflamed prostate may also present in a similar manner to a UTI. [patient.info]

    […] or infected prostate, which can obstruct the bladder from emptying properly Uncircumcised men may be more likely to experience a UTI than circumcised men Anal sex. [ada.com]

  • Renal Injury

    •Abnormal renal ultrasound • Hydronephrosis • Thick bladder wall • Renal scarring •Abnormal voiding post-febrile UTI •Post-second febrile UTI •Suspicion of • VUR • posterior urethral valves •Clinical suspicion of renal injury •Reduced renal function [slideshare.net]

    Long-term morbidity follows renal injury and scarring from upper tract UTI. [bmjpaedsopen.bmj.com]

Neurologic

  • Seizure

    Glutamine may increase the risk of mania or seizures in susceptible people and may interfere with some anticonvulsant medications. [soc.ucsb.edu]

    […] are typically used because they are generally considered safe in pregnancy.[77] A kidney infection during pregnancy may result in premature birth or pre-eclampsia (a state of high blood pressure and kidney dysfunction during pregnancy that can lead to seizures [en.wikipedia.org]

Workup

With the diagnosis of upper UTI, a radiographic workup is needed to identify which patients are susceptible to renal damage. [ci.nii.ac.jp]

No evidence of any associated malignancy was found after thorough workup. She was diagnosed as PC Type 1. She was put on topical steroids and orally on acetretin 25 mg OD. [idoj.in]

(See Workup.) Successful emergent management includes selection of appropriate antimicrobial therapy with recommendations for follow-up care. [emedicine.medscape.com]

X-Ray

  • Nephrolithiasis

    […] infection and nephrolithiasis. [ncbi.nlm.nih.gov]

    Nephrolithiasis is suspected. There is painless gross hematuria or new renal insufficiency. Fever persists for ≥ 72 h. 17. [slideshare.net]

    Differential Diagnosis The American Urological Association has identified conditions that can cause symptoms similar to UTI, including [4] : STDs: Genital Herpes, Gonorrhea, Chlamydia, Trichomonas Inflammatory disorders: Vaginitis, Prostatitis, Urethritis Nephrolithiasis [physio-pedia.com]

    Nephrolithiasis (hematuria and flack pain) mimics pyelonephritis. Chronic pelvic pain syndrome (CPPS) in males mimics prostatitis. [infectiousdiseaseadvisor.com]

Microbiology

  • Chlamydia

    The skin around your urethra may have bacteria, such as Escherichia Coli, gonococcus, and Chlamydia trachomatis, which can easily enter the urethra and infect it. [curejoy.com]

    Urethritis also may be caused by microorganisms that are transmitted through sexual contact, including gonorrhea and Chlamydia. Another form of male urinary infection is prostatitis which is an inflammation of the prostate. [health.harvard.edu]

    Some bladder infections in both men and women are linked to sexually transmitted infections, including Chlamydia trachomatis, mycoplasma, and ureaplasma. The parasite trichomonas can also cause similar symptoms. [webmd.com]

    NSAIDs) or radiation-induced cystitis Other diseases of the bladder (e.g., urolithiasis, bladder cancer, foreign objects) Vaginitis Pelvic inflammatory disease (PID) Prostatitis Urethritis with sexually transmitted infections (Neisseria gonorrhoeae, Chlamydia [amboss.com]

    Causes[edit] The disease is classified as either gonococcal urethritis, caused by Neisseria gonorrhoeae, or non-gonococcal urethritis (NGU), most commonly caused by Chlamydia trachomatis. [en.wikipedia.org]

  • Chlamydia Trachomatis

    Some bladder infections in both men and women are linked to sexually transmitted infections, including Chlamydia trachomatis, mycoplasma, and ureaplasma. The parasite trichomonas can also cause similar symptoms. [webmd.com]

    The skin around your urethra may have bacteria, such as Escherichia Coli, gonococcus, and Chlamydia trachomatis, which can easily enter the urethra and infect it. [curejoy.com]

    trachomatis, etc.), Candida, or irritants Trauma Structural abnormalities of the urethra, e.g., diverticula or strictures References:[16][17][18][19] The differential diagnoses listed here are not exhaustive. [amboss.com]

    Causes[edit] The disease is classified as either gonococcal urethritis, caused by Neisseria gonorrhoeae, or non-gonococcal urethritis (NGU), most commonly caused by Chlamydia trachomatis. [en.wikipedia.org]

    Other infections of the genital tract such as with C. albicans, herpes simplex, Chlamydia trachomatis and Gardnerella spp. may also produce similar symptoms in some women. [patient.info]

Treatment

An approach to evaluating antibacterial agents in the treatment of urinary tract infections. Clin Infect Dis 1992; 14: S246–251. PubMed Google Scholar 21. Stamey TA. Pathogenesis and Treatment of Urinary Tract Infections. [link.springer.com]

With prompt antibiotic treatment, most people recover quickly. [ada.com]

Current recommendations suggest that the treatment period should be no longer than three days in women with uncomplicated UTI, although should remain at seven days for the treatment of UTIs in men.[1] First-line therapy in mild cases of uncomplicated [patient.info]

It is the latest locally published guideline on the treatment of UTI in adults. [smj.org.sg]

Explain that prophylactic treatment does not modify the natural history of recurrent urinary tract infections. When such treatment ceases, even after long periods of treatment, more than 50% of women will have another infection within three months. [bmj.com]

Prognosis

[…] immunocompromised status especially virulent pathogen factors that may make a patient complicated 1 male childhood UTIs immunocompromised pregnancy elderly diabetes mellitus failed antibiotic course extended symptoms before presentation Treatment and prognosis [radiopaedia.org]

Prognosis of Urinary Tract Infection (UTI) Lower urinary tract infections are seldom complicated and complete recovery is expected with a short course of antibiotics. [healthengine.com.au]

Prognosis Complications may include secondary infection that is usually well controlled by antibiotics therapy. [orpha.net]

Prognosis Once a woman has been cured of cystitis, she has a 20% chance of developing a second infection. After the second infection, she has a 30% risk of developing a third. [drugs.com]

Etiology

The etiology of candidemia in this patient and the reason she developed progressive ocular symptoms after starting antifungal treatment are reviewed. [ncbi.nlm.nih.gov]

Etiology Pathogens Bacteria: usually caused by an ascending bacterial infection from the urethra Enterobacteriaceae (gram-negative rods) Escherichia coli: in ∼ 80% of UTIs Proteus mirabilis: ; urease-producing → causes alkaline urine with an ammonia smell [amboss.com]

Etiology Although historically two subtypes have been described, PC-1 and PC2, it is today recommended to classify PC patients into four subgroups based the underlying molecular etiology: PC-K6a, PC-K6b, PC-K16 and PC-K17, as PC is caused by dominant [orpha.net]

Etiology and risk factors N Engl J Med. 2012 Mar 15;366(11):1028-37. Lancet Infect Dis. 2004 Oct;4(10):631-5. Etiology Most commonly due to infection with Escherichia coli species (80-90% of cases). [pathophys.org]

The term urinary tract infection (UTI) covers a heterogeneous group of conditions with different etiologies, which have as their common factor the presence of bacteria in the urinary tract, as this is usually sterile, associated with variable clinical [guiasalud.es]

Epidemiology

Klebsiella spp. as nosocomial pathogens: epidemiology, taxonomy, typing methods, and pathogenicity factors. Clin Microbiol Rev 11, 589 –603. [Google Scholar] Sahly, H., Aucken, H., Benedí, V. J., Forestier, C., Fussing, V., Hansen, D. [jmm.microbiologyresearch.org]

American Journal of Epidemiology 151(12): 1194-1205. Encyclopedia of Health, 7th New York: Marshall Cavendish, 2010. Kidney Health Australia. 2014. “Urinary Tract Infections Fact Sheet.” Nitzan, O., Elias, M., Chazan, B. & Saliba, W. 2015. [utipure.com]

American Journal of Epidemiology, October 2004. Cochrane Database. Lynch, D. Am Fam Physician. December 1, 2004. National Institute of Diabetes and Digestive and Kidney Diseases. National Women’s Health Information Center. Nemours Foundation. [webmd.com]

The epidemiology of UTI in the tropics is less well documented. UTIs appear to be common and associated with structural abnormalities. [emedicine.medscape.com]

Journal of clinical epidemiology. 2006;59(9):970-9. 21. Bont J, Hak E, Hoes AW, Macfarlane JT, Verheij TJ. [verenso.nl]

Pathophysiology

In conclusion, based on the importance of the hemostatic component in the pathophysiology of infections, our findings of platelet count and MPV and predictivity of the type of the organism would suggest the usefulness of the routine measurements in children [ncbi.nlm.nih.gov]

However, indi¬vi¬duals with¬out these recogni¬zed traits and conditions also develop OSA making the etiology and pathophysiology unclear. [umu.se]

"Pathophysiology of bradykinesia in Parkinson's disease The term bradykinesia was first used by James Parkinson to describe one of the cardinal features of the disease that now bears his name. [dict.leo.org]

Pathophysiology 7. Etiology The bacteria that most often cause cystitis and pyelonephritis are the following: Enteric, usually gram-negative aerobic bacteria (most often) Escherichia coli : 75 to 95% of cases. [slideshare.net]

Pathophysiology of Complicated Urinary Tract Infections. Medscape Reference [On-line information]. Available online at http://emedicine.medscape.com/article/2039975-overview. Accessed October 2012. Brusch, J. (Updated 2012 February 1). [labtestsonline.org]

Prevention

Recurrent UTIs in Women: Treatment & Prevention [plushcare.com]

The exact amount of juice or pills needed and how long you need to take them to prevent infection are being studied. Treatment with an estrogen cream or pills is being studied as a way to prevent UTIs in menopausal women. [m.acog.org]

Cranberry extracts do not help treat existing UTIs but may help prevent their development. This is because cranberries contain compounds called proanthocyanidins that prevent E. coli from sticking to the walls of the digestive and urinary tracts. [medicalnewstoday.com]

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