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Uremic Pneumonitis

Lung Uremic


Presentation

  • This patient had no access to formal healthcare and presented with a now rare and “forgotten” clinical entity.[shmabstracts.com]
  • Mason, MD now presents the fifth edition in full color with new images and highlighted clinical elements.[books.google.com]
  • (in 85% of patients) Absent (unless pericarditis is present) Rare; a pleural friction rub is present in 3% of patients S 3 sound, pulmonary congestion Absent May be present Absent Table 4.[aafp.org]
  • Similarly to our cases, 81% of the patients were treated with PE; nevertheless 61% of the patients died or presented ESRD.[em-consulte.com]
Pallor
  • He had marked pallor, with a hyperdynamic precordium and coarse rales bilaterally. There was no jugular venous distension, pericardial friction rub, stupor, asterixis or peripheral edema.[shmabstracts.com]
  • He had mild conjunctival pallor, a pan systolic murmur best heard at the left 3rd intercostal space midclavicular line, crackles on both lung fields. He also had bilateral pedal edema, but no jugular venous distension, or pericardial friction rib.[imedpub.com]
  • Approximately 3 to 10 days after the development of gastroenteritis, additional symptoms appear including sudden onset of paleness (pallor), irritability, weakness, diminished excretion of urine (oliguria) or no urine [anuria], and lack of energy (lethargy[rarediseases.org]
Coarse Rales
  • He had marked pallor, with a hyperdynamic precordium and coarse rales bilaterally. There was no jugular venous distension, pericardial friction rub, stupor, asterixis or peripheral edema.[shmabstracts.com]
Exertional Dyspnea
  • In January 2006, he again complained of cough, sputum, and exertional dyspnea for 3 days. On physical examination, the respiratory rate was 18/min and the heart rate was 104 beats/min. However, there was no fever, edema, or cyanosis.[kjim.org]
Pericardial Friction Rub
  • There was no jugular venous distension, pericardial friction rub, stupor, asterixis or peripheral edema. At presentation, his serum creatinine and BUN levels were markedly elevated (41.5 and 218 mg/dl) with hemoglobin of 4.6 g/dl.[shmabstracts.com]
  • friction rub and thus allows differentiation from a pleural rub.[aafp.org]
  • A pericardial friction rub was audible, and an echocardiogram demonstrated a small pericardial effusion. A renal ultrasound showed normal sized kidneys with no evidence of renal vein thrombosis.[pedsccm.org]
Dysgeusia
  • A 23–year–old gentleman presented with a 2–week history of cough, epistaxis, hemoptysis and shortness of breath on exertion, loss of appetite, fatigue, nausea and dysgeusia. He denied rash or arthralgias and reported normal urinary output.[shmabstracts.com]
Asterixis
  • There was no jugular venous distension, pericardial friction rub, stupor, asterixis or peripheral edema. At presentation, his serum creatinine and BUN levels were markedly elevated (41.5 and 218 mg/dl) with hemoglobin of 4.6 g/dl.[shmabstracts.com]
Erythema
  • Can cause an arthritis with symptoms of Joint pain,swelling and erythema.[medicaljoyworks.com]
  • Signs of infection include erythema, skin breakdown, purulent drainage and, occasionally, bleeding from a pseudoaneurysm. Fever and other signs of sepsis may be present.[antimicrobe.org]
Epistaxis
  • A 23–year–old gentleman presented with a 2–week history of cough, epistaxis, hemoptysis and shortness of breath on exertion, loss of appetite, fatigue, nausea and dysgeusia. He denied rash or arthralgias and reported normal urinary output.[shmabstracts.com]

Workup

  • Now, although empiric antibiotic coverage is mainly based on the treatment setting, the diagnostic workup and empiric antibiotics can differ a bit based on the organisms that are suspected based on the appearance of the chest x-ray.[osmosis.org]
  • Workup to identify the predisposing factor including human immunodeficiency virus (HIV), parvovirus (B19), cytomegalovirus (CMV), quantiferon tuberculosis testing were all negative. Genetic testing was deferred to the outpatient setting.[imedpub.com]
  • The workup to define antibiotic failure includes a tube dilution MIC/MBC ratio; the higher the ratio, the greater limitation of antibiotics. A serum bacteriocidal level (Schlicter test) is also useful.[antimicrobe.org]
  • Clearly, the diagnostic workup and management will be directed by the medical history and clinical examination and investigation findings.[sjkdt.org]
  • Table 1 HUSs that can present in childhood – a comprehensive laboratory workup is designed to distinguish these entities from one another, particularly when the clinical presentation is not straightforward STEC HUS Pathophysiology Shiga toxin (Stx) infection[karger.com]
Atelectasis
  • […] hypersensitivity pneumonitis Aka: chronic extrinsic allergic alveolitis, pathology: proliferation of epithelial cells, elaboration of reticulum fibres, findings: interstitial reticulonodular pattern (basilar distribution), volume loss (cicatrization atelectasis[kmle.co.kr]
  • On a chest x-ray, atelectasis shows up as a wedge-shaped region with its apex at the hilum with an ipsilateral shift of structures due to volume loss.[osmosis.org]
  • Atelectasis of lung may cause trachea to deviate toward same side as diseased lung.[kumc.edu]
  • There is diaphragmatic elevation resulting in plate-like atelectasis. Only gold members can continue reading.[thoracickey.com]
  • Diffuse alveolo-capillary damage, interstitial and intra-alveolar edema, widespread atelectasis, alveolar hemorrhages and pulmonary hyaline membranes are characteristic but not pathognomonic findings in uremic pneumonitis.[imedpub.com]
Pulmonary Infiltrate
  • The presence of a new or progressive pulmonary infiltrate and a clinical syndrome consistent with infection helps to confirm the diagnosis.[cancertherapyadvisor.com]
  • A patient was considered to have CAP if, at the time of hospital admission, he/she presented with respiratory symptoms and sputum, and exhibited pulmonary infiltrates on chest radiographs.[birpublications.org]
  • infiltrate in a patient with lower respiratory tract symptoms highly confirms the evidence of a pulmonary process, but does not confirm the presence of bacteria in the lower respiratory tract.[cancertherapyadvisor.com]
  • There are episodes compatible with lung infection and isolation of microorganisms in significant concentrations in ventilated patients that do not present visible pulmonary infiltrate, known as respirator-associated tracheobronchitis.[archbronconeumol.org]
  • Patients with SLE who present with a febrile illness, cough with or without productive sputum, and new pulmonary infiltrates must be considered to have an infectious pneumonia, although acute lupus pneumonitis and diffuse alveolar hemorrhage may have[thoracickey.com]
Reticulonodular Pattern
  • pattern (basilar distribution), volume loss (cicatrization atelectasis) in upper lobes, pleural effusion (rare), lymph node enlargement may occur (12 Dec 1998) interstitial pneumonitis A form if pneumonia which involves the interstitial tissues (connective[kmle.co.kr]
Lymphocytic Infiltrate
  • There is a dense lymphocytic infiltrate, broadening the interstitium and lymphoid follicles. UIP is the underlying lesion of idiopathic pulmonary fibrosis and can also appear in all the collagen vascular diseases.[thoracickey.com]
  • Like the lymphocytic infiltrate described herein, the neutrophils were located primarily within the alveolar walls and the pattern did not simulate the airspace involvement of typical acute pneumonia.[archivesofpathology.org]

Treatment

  • Lists the latest drugs used for the treatment of cardiopulmonary disorders. Includes information on laboratory medicine and pediatrics to help you apply cardiopulmonary principles to practice.[books.google.com]
  • The diagnosis was supported by the tomographic picture of the lung and the severe state of uremic poisoning, as well as an ex juvantibus criterion: intensive dialytic treatment together with broad-spectrum antibiotic therapy resulted in progressive improvement[ncbi.nlm.nih.gov]
  • Renal Failure Prevention and Treatment in the 19808 It appears logical to juxtapose in this volume prevention-low cost and nonmorbid-with uremia therapy, which is very morbid and very high cost.[books.google.com]
  • Next Document: Baclofen in the treatment of spasticity.[biomedsearch.com]

Prognosis

  • Anti-Glomerular Basement Membrane Disease* / diagnosis, epidemiology, etiology, pathology, radiography, therapy Capillary Permeability Female Humans Lung / pathology Male Middle Aged Pneumonia / complications*, pathology, physiopathology, radiography Prognosis[biomedsearch.com]
  • A subgroup of (young) patients presenting with a mild nephropathy and not requiring dialysis has a good prognosis, however.[adc.bmj.com]
  • Deschenes Prognosis of Streptococcus pneumoniae -induced hemolytic uremic syndrome Pediatr Nephrol, 16 (2001), pp. 362-365 [9.] D.J. Krysan, J.T.[analesdepediatria.org]
  • This case highlights two important facts: the possibility of occurrence of pHUS in young infants on one hand and the fact that the histological study is a valuable pointer of prognosis on the other. 1. Kaplan BS, Cleary TG, Obrig TG.[sjkdt.org]
  • Nathanson S, Deschenes G. prognosis of streptococcus pneumonia induced hemolytic uremic syndrome. Pediatr Nephrol 2001;16:362-365. banerjee R, Hersh Al, Newland J, et al.[journals.sbmu.ac.ir]

Etiology

  • , pathology, radiography, therapy Capillary Permeability Female Humans Lung / pathology Male Middle Aged Pneumonia / complications*, pathology, physiopathology, radiography Prognosis Pulmonary Edema / physiopathology Uremia / etiology* From MEDLINE /PubMed[biomedsearch.com]
  • High affinity to the respiratory epithelium makes Chlamydophila pneumoniae a common etiological agent. Constitutional symptoms (malaise, lethargy etc.)[medicaljoyworks.com]
  • Incidence of specific etiology and role of methods for specific etiologic diagnosis of primary acute pericarditis. Am J Cardiol. 1995;75(5):378–382. 13. Ginzton LE, Laks MM.[aafp.org]
  • The reported rates for polymicrobial etiology differ considerably between 5.7 and 38.4% [7], [8].[ejbronchology.eg.net]
  • […] chlorine Bronchial obstruction ( obstructive pneumonitis or post-obstructive pneumonitis ) Ascariasis (during parasite migration) Diagnosis [ edit ] A chest X-ray or CT is necessary to differentiate between pneumonitis and pneumonia of an infectious etiology[en.wikipedia.org]

Epidemiology

  • JAPAN Other Details: Languages: jpn Pagination: 1639-48 Citation Subset: IM Export Citation: APA/MLA Format Download EndNote Download BibTex MeSH Terms Descriptor/Qualifier: Adolescent Adult Aged Anti-Glomerular Basement Membrane Disease* / diagnosis, epidemiology[biomedsearch.com]
  • The new vaccine virus was developed by the WHO Collaborating Center for the Surveillance, Epidemiology and Control of Influenza at the CDC in Atlanta.[cidrap.umn.edu]
  • Children Pneumonia Epidemiology 2014 ERS[erj.ersjournals.com]
  • Epidemiology of our cluster of resp HUS remains uncertain. No common source or type for S. pneumoniae was determined. No new resp HUS case has been diagnosed in the past 16 months.[nature.com]
  • Epidemiology of Streptococcus pneumoniae-induced hemolytic uremic syndrome in Utah children. Pediatr Infect Dis J 2010; 29:712. Proulx F, Liet Jm, David M, et al. Hemolytic uremic syndrome associated with invasive streptococcus pneumonia infection.[journals.sbmu.ac.ir]
Sex distribution
Age distribution

Pathophysiology

  • It integrates key concepts of pathophysiology, clinical manifestations, diagnostic tests and laboratory information and findings with clinically important medical and surgical interventions and pharmacologic therapies — then applies the material to physical[books.google.com]
  • The results suggest that uremic pneumonitis does, indeed, exist as part of the pathophysiology of renal failure, and may occur without detectable evidence of cardiac decompensation.[annals.org]
  • Pathophysiology of hemolysis in infections with Hemophilus influenzae type b. J Clin Invest. 1986;77(4):1340-1348. Ramakrishnan M, Moïsi JC, Klugman KP, et al.[journals.sbmu.ac.ir]
  • The plural form of HUS (‘Syndrome’ in German) was deliberately used in anticipation of the epidemiological, clinical, and pathophysiological heterogeneity of the disease.[adc.bmj.com]
  • Pathophysiology of accelerated aging in uremia The pathophysiology of the accelerated aging process in dialysis patients is multifactorial.[academic.oup.com]

Prevention

  • Renal Failure Prevention and Treatment in the 19808 It appears logical to juxtapose in this volume prevention-low cost and nonmorbid-with uremia therapy, which is very morbid and very high cost.[books.google.com]
  • Preventing the spread of E.coli To help prevent infection with STEC and the development of HUS: Ensure proper hand washing, especially after handling raw meat.[betterhealth.vic.gov.au]
  • In the same manner, the manipulation of the respirator tubes is also a risk for NP. 12 Preventive Measures The strategies involved in the prevention of NP can be directed towards modifiable risk factors for colonization and aspiration, 5,7,13–15 in addition[archbronconeumol.org]
  • In recent years, most cases of SP-HUS have been caused types of SP that are not prevented by the PCV-7 vaccine—particularly a strain called serotype 3.[wolterskluwer.com]

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