PATIENT: A 43-year-old male patient was admitted to our hospital with inguinal lymphadenopathy and pruritus. He turned out to be uremic due to focal segmental glomerulosclerosis (creatinine 4.5 mg/dl, MDRD creatinine clearance 12 ml/min). [ncbi.nlm.nih.gov]

Alternative therapeutic approaches, including topical, oral, and intravenous drugs; dialysis modifications; homeopathic therapies; and physical treatments have been used, but few evidence-based studies exist to support their utility. [ncbi.nlm.nih.gov]

Parathyroid hormone increases serum levels of histamine and mast cell proliferation and dramatic improvement in pruritus has been noted after parathyroidectomy [ 65 - 67 ]. [omicsonline.org]