Presentation
A 44-year-old, previously healthy woman, gravida 3, para 3, presented with a life-threatening uterine hemorrhage. She was subsequently diagnosed with APML by bone marrow biopsy. [ncbi.nlm.nih.gov]
Entire Body System
- Fatigue
Other complications of uterine atony include: orthostatic hypotension, which is lightheadedness or dizziness due to low blood pressure anemia fatigue an increased risk of postpartum hemorrhage in a later pregnancy Anemia and fatigue after birth also increase [healthline.com]
The woman has symptoms of significant blood loss, such as low blood pressure, a rapid heart rate, dizziness, light-headedness, fatigue, and weakness. Excessive blood loss usually occurs soon after delivery but may occur as late as 1 month afterward. [msdmanuals.com]
MORE ON PREGNANCY HEALTH AND SYMPTOMS Fatigue During Pregnancy Morning Sickness Gestational Diabetes From the What to Expect editorial team and Heidi Murkoff, author of What to Expect When You're Expecting. [whattoexpect.com]
- Infertility
The procedures used usually do not cause infertility, abnormalities in menstruation, or other lasting problems. [msdmanuals.com]
Normal fetal growth and umbilical artery Doppler waveforms have been described as being associated with perinatal survival. [16] The frequency of subchorionic hematoma has been shown to be high with infertility treatment by in vitro fertilization (IVF [emedicine.medscape.com]
Even if you need sutures on your uterus, infertility shouldn’t occur. However, in the rare instance of needing a hysterectomy, you won’t be able to have another baby. [healthline.com]
Local mononuclear cell infiltrates in infertile patients with endometrial macropolyps versus micropolyps. [accessmedicina.mhmedical.com]
- Chills
You may have PPH if you have heavy bleeding from the vagina that doesn’t slow or stop, blurred vision, chills, or if you feel weak or feel faint. You’re more likely to have PPH if you’ve had it in the past. [marchofdimes.org]
[…] previously described management has been conducted (tutorial author) It is very expensive compared with Methergine and Pitocin (tutorial author) The side effects are very uncomfortable and include nausea, vomiting, diarrhea, flushing or hot flashes and chills [library.med.utah.edu]
- Rigor
Acute PPH is often accompanied by signs of shock such as reduced blood pressure, tachycardia or low pulse rate, fever, rigors, and faintness or collapse. These are the most definite indications of a PPH, but also the most dangerous. [wikihow.com]
Rigors. Tachycardia. Tenderness of the suprapubic area and adnexae. Elevated fundus which feels boggy in RPOC. Investigation FBC. Blood cultures. Check MSU. High vaginal swab; also gonorrhoea/chlamydia. [patient.info]
- Gangrene
The most dramatic effects of poisoning are hallucinations and convulsions, prolonged vasospasm and damage of endothelium that may result in gangrene, and stimulation of uterine smooth muscle, which in pregnancy may result in abortion. [en.wikiversity.org]
Skin
- Hirsutism
Other symptoms caused by changes in hormone levels may include: Excessive growth of body hair in a male pattern (hirsutism). Hot flashes. Mood swings. Tenderness and dryness of the vagina. [medigoo.com]
- Ulcer
May have ULCERATED cervix. Blood is dark, bad smelling, continuous. Flow is increased from the least exertion. Ipecac (uterine hemorrhage) Profuse bleeding with continuous NAUSEA, faintness and weakness. No relief, even from vomiting. [quizlet.com]
Urogenital
- Uterine Hemorrhage
The uterine hemorrhage was treated with hormonal therapy and uterine artery embolization (UAE), which failed to control the bleeding. Radiofrequency, impedance-controlled endometrial ablation was successfully utilized. [ncbi.nlm.nih.gov]
- Vaginal Bleeding
No further vaginal bleeding was noted up to eight weeks posttherapy, with an increase in hemoglobin in each patient. Each patient avoided emergent hysterectomy and/or blood transfusion. [ncbi.nlm.nih.gov]
Vaginal Bleeding Between Periods. Healthline. https://www.healthline.com/health/vaginal-bleeding-between-periods 7. Christiano, D. (2019, March 8). Everything You Should Know About Menometrorrhagia. [medtronic.com]
What conditions cause abnormal vaginal bleeding in women who are ovulating regularly? Abnormal vaginal bleeding in women who are ovulating regularly, most commonly involve excessive, frequent, irregular, or decreased bleeding. [medicinenet.com]
- Metrorrhagia
Abstract A 57-year-old postmenopausal woman with end-stage liver disease secondary to alcoholic cirrhosis, esophageal varices, severe alcoholic cardiomyopathy, and metrorrhagia causing persistent anemia despite multiple transfusions presented with heavy [ncbi.nlm.nih.gov]
Menstrual periods at irregular intervals (metrorrhagia) Irregular menstrual periods (metrorrhagia) can be due to benign growths in the cervix, such as cervical polyps. The cause of these growths is usually not known. [medicinenet.com]
MEDMOS Types [ edit ] Metrorrhagia (metro = womb, -rrhagia = excessive flow [1] ) is uterine bleeding at irregular intervals, particularly between the expected menstrual periods. [2] Postcoital bleeding is vaginal bleeding after sexual intercourse. [en.wikipedia.org]
- Oligomenorrhea
WebMD. https://www.webmd.com/women/oligomenorrhea-definition-signs-and-treatments 4. Young, B. (2018, February 28). Polymenorrhea. Healthline. https://www.healthline.com/health/polymenorrhea 5. Oehler, M. K., & Rees, M. C. P. (2003). [medtronic.com]
Workup
Based on the clinical presentation, a workup for thyroid disorders, liver disorder, sepsis, or leukemia may be indicated. Endometrial tissue sampling should be performed in patients with AUB who are older than 45 years as a first-line test. [acog.org]
Acta Obstet Gynecol Scand 79:1006, 2000 [PubMed: 11081688] Shi AA, Lee SI: Radiological reasoning: algorithmic workup of abnormal vaginal bleeding with endovaginal sonography and sonohysterography. [accessmedicina.mhmedical.com]
Treatment
The patients were investigated before and after hormonal treatment aimed at restoring normal hemostasis and the control of menstrual function. [popline.org]
Treatment Limited evidence and expert opinion support recommendations for treatment. [acog.org]
Treatment usually involves medication to correct the hormone imbalance. [medigoo.com]
Continued Your treatment also can depend on whether you plan to have children. It might not be safe to get pregnant after some treatments, while others can make it impossible. [webmd.com]
Oligomenorrea: Definition, Signs, and Treatments. (2021, June 30). WebMD. https://www.webmd.com/women/oligomenorrhea-definition-signs-and-treatments 4. Young, B. (2018, February 28). Polymenorrhea. [medtronic.com]
Prognosis
Therefore, the prognosis of patients with this type of hematoma is worse than the prognosis of patients with hematoma early in first trimester. [12, 13] The subchorionic hematoma often regresses, especially if it is small or moderate in size. [emedicine.medscape.com]
Prognosis 90% of cases of postpartum endometritis treated with antibiotics improve within 48-72 hours. [ 16 ] If this is not the case, the patient should be re-evaluated. [patient.info]
A doctor or radiologist can then explain the problem, the prognosis, and the risks. Fortunately, those who haven’t experienced heavy bleeding or those who have very small clots are probably not going to deal with any further symptoms or problems. [newkidscenter.com]
Etiology
The author also discussed the etiological mechanism of the disease and the theory that guided him in designing the prescription in the light of TCM. [ncbi.nlm.nih.gov]
Etiologies of Acute Abnormal Uterine Bleeding The etiologies of acute AUB, which can be multifactorial, are the same as the etiologies of chronic AUB. [acog.org]
Etiology Common causes are trauma; congenital abnormalities; pathologic processes (such as tumors; infections, esp. of the alimentary, respiratory, and genitourinary tracts); and generalized vascular disorders such as purpuras and coagulation defects. [medical-dictionary.thefreedictionary.com]
Etiology Pneumonic: The traditional pneumonic “4Ts: tone tissue trauma thrombosis Carusi, Daniela, Yaa, Maame, and Yiadom, A B. 2010. Pregnancy, Postpartum Hemorrhage. Emedicine. [primumn0nn0cere.wordpress.com]
A rare etiology of delayed postpartum hemorrhage. J Obstet Gynaecol Can JOGC J Obstétrique Gynécologie Can JOGC. 2008 Mar;30(3):239-43. PubMed | Google Scholar Delesalle C, Dolley P, Beucher G, Dreyfus M, Benoist G. [panafrican-med-journal.com]
Epidemiology
Epidemiology Obstetric haemorrhage is no longer a major cause of maternal death in the UK. [patient.info]
ANDERSON, M.D., F.A.A.F.P., is director of the obstetrics and gynecology curriculum at Forbes Family Medicine Residency Program, Western Pennsylvania Hospital Forbes Regional Campus, Monroeville, Pa., and instructor of family medicine and clinical epidemiology [aafp.org]
Epidemiology of postpartum haemorrhage: a systematic review. Best Pract Res Clin Obstet Gynaecol. 2008;22:999-1012. [ PubMed ] doi: 10.1016/j.bpobgyn.2008.08.004. Chhabra S, Sirohi R. [apicareonline.com]
Pathophysiology
However, prediction of occurrence of atonic uterus is difficult before delivery, because the precise pathophysiological mechanism to trigger this condition remains unclear. [ncbi.nlm.nih.gov]
If it does, there is probably other pathophysiology occuring. At this point an obstetric consultant should be contacted in the event that high acuity medical or surgical procedures are needed. [library.med.utah.edu]
Prevention
The branched configuration functions to prevent tissue from obstructing the medially oriented openings. [google.sr]
MEA successfully controlled bleeding in all four patients, thereby preventing them from undergoing hysterectomy. Our results suggest that emergency MEA is a promising way to control a life-threatening uterine hemorrhage. [ncbi.nlm.nih.gov]
Can abnormal uterine bleeding be prevented or avoided? If your abnormal uterine bleeding is caused by hormonal changes, you will not be able to prevent it. But if your hormonal changes are caused by being overweight, losing weight could help. [familydoctor.org]
Tocolytics are stopped and oxytocin is restarted following reduction to prevent recurrence. [emergencymedicinecases.com]