Edit concept Question Editor Create issue ticket

Uveal Disease


Presentation

  • Patients tend to present a decade earlier and early macular involvement rapidly impairs vision.[patient.info]
  • Iris melanoma presents as an iris pigmented mass. Ciliary body melanoma can cause blurred vision. Loss of vision, flashing light sensation, exudative retinal detachment are some of the common presentations of a choroidal melanoma.[my.clevelandclinic.org]
  • Thrombocytopenia: case definition and guidelines for collection, analysis, and presentation of immunization safety data. Vaccine 2007;25: 5717-5724.[sukl.sk]
  • Presentations on patient care, literature review, or current treatments are discussed by all in attendance. Administration Time: The resident will be given administration time depending upon clinic availability.[pacificu.edu]
  • The case presented in this section (below) demonstrates one such case. Symptoms Depending on the location of the leukemic infiltrates, patients will have different symptoms.[eyecancer.com]
Asymptomatic
  • Presentation Many patients are asymptomatic but they may complain of metamorphopsia or impaired vision over time. Investigations Fluorescein angiogram. Treatment This depends on the underlying cause but asymptomatic folds do not require treatment.[patient.info]
  • […] development of metastases, consideration of active surveillance and management of patients following adjuvant therapy has been recommended within the UK Uveal Melanoma National Guidelines. 40 Although no survival benefit as a result of the early detection of asymptomatic[bjo.bmj.com]

Workup

  • If one of the high-risk indicators, mentioned previously is found, there is reasonable evidence for potential growth and many authorities recommend advancing the workup and obtaining a biopsy.[eyewiki.aao.org]
Lymphocytic Infiltrate
  • Immunology [ edit ] The normal uvea consists of immune competent cells, particularly lymphocytes, and is prone to respond to inflammation by developing lymphocytic infiltrates.[en.wikipedia.org]
  • infiltration, fibrovascular loops) the location of the tumor (with melanomas involving the ciliary body conferring the highest risk of metastasis), and the extent of metastasis. [12] While the cellular makeup of biopsied tumors remains very useful, recent[eyewiki.aao.org]

Treatment

  • Not only are there better treatments for diseases where treatments existed, we now have effective therapy for previously untreatable and blinding eye disorders.[books.google.com]
  • Liver-targeted treatment options The liver is the organ most commonly affected by metastatic disease.[bjo.bmj.com]
  • Treatment Treatment Options: Simple iris colobomas usually do not require treatment. The visual prognosis depends upon the structures involved.[disorders.eyes.arizona.edu]
  • Wiegel Karger Medical and Scientific Publishers, 1997 - 301 Seiten This book discusses current controversial topics and therapeutic strategies in the treatment of malignant and benign ocular diseases, with special emphasis on ocular tumors.[books.google.de]

Prognosis

  • Metastases are most frequently localised to the liver and, as few patients are candidates for potentially curative surgery, this is associated with a poor prognosis.[bjo.bmj.com]
  • The visual prognosis depends upon the structures involved. Those with microcornea usually have a lower acuity and, of course, eyes with the most extensive involvement of the uveal tract and/or the optic nerve may have the least vision.[disorders.eyes.arizona.edu]
  • Prognosis - this condition recurs over months and frequent foveal involvement gives rise to a relatively poor prognosis. Multiple evanescent white dot syndrome (MEWDS) Nature - uncommon, idiopathic and self-limiting condition.[patient.info]
  • Iris melanoma: features and prognosis in 317 children and adults. J AAPOS. 2012 Feb;16(1):10-6. 4.0 4.1 Kujala E, Makitie T, Kivela T (2003) Very Long-Term Prognosis of Patients with Malignant Uveal Melanoma.[eyewiki.aao.org]
  • Many ocular eye diseases should be detected early for a better prognosis and monitored regularly.[vision-care.com]

Etiology

  • […] fungal infection, orbital cellulitis, concern in diabetics Kochers sign, Von Graefes sign Periorbital swelling and shared cosmetics (make-up) Symblepharon and Ankyloblepharon Zeis or Moll gland infection Obese man with sleep apnea Canaliculitis (#1 etiology[quizlet.com]
  • Seeing this great use of the journal supplement medium, we sought to complement their guide with one of our own that summarized the description and etiology of the most frequently encountered ocular diseases, along with abbreviated management discussions[reviewofoptometry.com]
  • […] age-adjusted incidence of this rare malignancy has been reported as 5.1 per million and has remained stable since at least the early 1970’s. [1] These tumors most commonly arise unilaterally in Caucasians during the fifth to sixth decade of life. [1] Etiology[eyewiki.aao.org]

Epidemiology

  • […] management of ocular therapeutics into practice and to work in an integrated way with other health professionals so as to provide guided practical experience in the therapeutic management of ocular disease Related topics in: Pathophysiology Genetics Epidemiology[savvysciencepublisher.com]
  • Swerdlow AJ. (1983) Epidemiology of eye cancer in England and Wales, 1962-1977. Am J Epidemiol. 118:294-300.[photobiology.info]
  • Risk factors for the development of uveal melanoma include Caucasian ethnicity, welding, light eye colour (green or blue), dysplastic naevus syndrome, ocular melanocytosis and presence of germline BRCA1-associated protein 1 ( BAP1 ) mutations. 8–13 Epidemiology[bjo.bmj.com]
  • This definition requires clinical and laboratory confirmation (or epidemiological link to a confirmed case) that the actual disease is vaccine preventable, i.e. that the pathogen (including, where appropriate, type, subtype, variant, etc.) and clinical[sukl.sk]
Sex distribution
Age distribution

Pathophysiology

  • "Ocular Disease: Mechanisms and Management is invaluable in its emphasis on discussions of the pathophysiology of ocular disease.[amazon.com]
  • […] the skills to incorporate management of ocular therapeutics into practice and to work in an integrated way with other health professionals so as to provide guided practical experience in the therapeutic management of ocular disease Related topics in: Pathophysiology[savvysciencepublisher.com]
  • Obstructive Sleep Apnea and Coronary Ar te ry D i sease : F rom Pathophysiology to Clinical Implications. Obstructive sleep apnoea: brain structural changes and neurocognitive function before and after treatment.[semanticscholar.org]
  • Pathophysiology The pathogenesis of uveal effusion syndrome, also referred to as idiopathic ciliochoroidal effusion, though has not been clearly defined.[eyewiki.aao.org]
  • Nordlund JJ, Boissy RE, Hearing VJ, King RA, Ortonne J. (1998) The pigmentary system: Physiology and pathophysiology. Oxford University Press, New York.[photobiology.info]

Prevention

  • Read more about our Management of Ocular Disease An early diagnosis of glaucoma is the best prevention against this disease’s harmful effects.[coveeyecare.com]
  • For those who have diabetes, they're required to have an annual eye exam to help maintain and prevent any harm to the eye.[overlandoptical.com]
  • Commercially available moisture shields, plastic wraps, or swimming goggles may also be used to prevent the eye from drying.[emedicine.medscape.com]
  • Below is a list of services we provide for the prevention and management for diabetic ocular diseases.[visionsource-nfe2020.com]
  • Early detection and treatment could prevent vision loss. See an eye care professional right away if you have a sudden change in vision, if everything looks dim, or if you see flashes of light.[medlineplus.gov]

Ask Question

5000 Characters left Format the text using: # Heading, **bold**, _italic_. HTML code is not allowed.
By publishing this question you agree to the TOS and Privacy policy.
• Use a precise title for your question.
• Ask a specific question and provide age, sex, symptoms, type and duration of treatment.
• Respect your own and other people's privacy, never post full names or contact information.
• Inappropriate questions will be deleted.
• In urgent cases contact a physician, visit a hospital or call an emergency service!