This can lead to a type of fatigue that can only be cur … read more Dr. Rick Board Certified MD Doctoral Degree 13,344 satisfied customers I HAVE DRY EYES, GRANULATED EYE LIDS, BLOOD SHOT EYE. NO I HAVE DRY EYES, GRANULATED EYE LIDS, BLOOD SHOT EYE. [justanswer.com]

A few of the illnesses helped by osteopathic manipulation are spinal and joint conditions, arthritis, allergies, cardiac diseases, breathing dysfunctions, chronic fatigue syndrome, hiatal hernias, high blood pressure, headaches, digestive disorders, bladder [alternative-health-group.org]

There may be fever, headache, nausea, meningismus, dysacusia (discomfort caused by loud noises or a distortion in the quality of the sounds being heard), tinnitus, and/or vertigo. Eye symptoms can include orbital pain, photophobia and tearing. [en.wikipedia.org]

Signs & Symptoms Vogt-Koyanagi-Harada disease is initially characterized by headaches, very deep pain in the eyes, dizziness (vertigo), and nausea. [rarediseases.org]

The prodromic stage is characterized by nonspecific symptoms such as fever, headaches, nausea and vertigo, and then by neurologic symptoms such as muscle weakness, hemiparesis, hemiplegia, dysarthria and orbital pain. [orpha.net]

Initial onset of Vogt-Koyanagi-Harada syndrome is characterized by severe headache, deep pain in the eye, vertigo (feeling that the room is spinning), and nausea, followed in a few weeks by uveitis and vision loss. [healthcentral.com]

There may be fever, headache, nausea, meningismus, dysacusia (discomfort caused by loud noises or a distortion in the quality of the sounds being heard), tinnitus, and/or vertigo. Eye symptoms can include orbital pain, photophobia and tearing. [en.wikipedia.org]

[…] multifocal exudative retinal or retinal pigment epithelial detachments, disc hyperemia or edema, or “sunset glow” fundus, which is a yellow-orange appearance of the fundus due to depigmentation of the RPE and choroid, 3) neurologic signs, including tinnitus [aao.org]

The ocular symptoms were accompanied by tinnitus and marked dyspnea. Pulmonary consultation identified nonspecific pulmonary findings which were out of proportion to her dyspnea. [karger.com]

During the initial assessment by the Ophthalmologist, she complained about persistent tinnitus and headache, considered as unspecific by the Otorhinolaryngologist and Neurologist. [omicsonline.org]

Clinical manifestations include anterior and posterior uveitis, vitiligo, tinnitus, exudative retinal detachment and cerebrospinal fluid pleocytosis. Onset is usually in the second to fifth decade of life. [aaopt.org]

In a retrospective review of 48 patients, Beniz et al. report the prevalence of headache (67%), tinnitus (17%), dysacusis (13%), vitiligo (10%), alopecia (13%), and poliosis (6%). [omicsonline.org]

[…] inflammation Vogt in 1906 • Primary posterior uveitis exudative RDs CSF pleocytosis Einosuke Harada • B/l chronic iridocyclitis skin & hair depigmentation  Koyanagi • This constellation of findings was termed “uveitis with polosis, vitiligo, alopecia and dysacusis [de.slideshare.net]

Inner ear involvement Changes in the inner ear, such as dysacusis, hearing loss and vertigo, have been observed in 70 % of patients, especially during the prodromal stage. Tinnitus is present in 42 % [ 65 ]. [doi.org]

Ocular findings may be accompanied by lymphocytic meningitis, hearing impairment and/or tinnitus in a variable proportion of patients. [doi.org]

In the ophthalmologic stage, occurring a few days after the prodromic stage, patients complain of blurred vision, ocular pain, and photophobia or central scotoma (bilateral in 80% of cases). [orpha.net]

A 57-year-old man with no family history of neurologic disease was healthy until age 40 years, when he gradually experienced bilateral eye pain and blurred'' vision. [n.neurology.org]

Case Presentation An 18-year old woman with a history of astigmatism presented with the complaint of blurred vision in the right eye for two weeks. [omicsonline.org]

VKH often becomes bilateral, with patients experiencing blurred vision. “Sometimes there is pain and discomfort,” Dr. Tessler said. Patients also usually develop exudative retinal detachments. In fact, Dr. [healio.com]

Vogt-Koyanagi-Harada syndrome - see under Vogt, Alfred Vogt, Alfred, Swiss ophthalmologist, 1879-1943. limbal girdle of Vogt - corneal opacity that occurs in an arc concentric pattern. [medical-dictionary.thefreedictionary.com]

[…] depigmented Hair), Hearing [..] 0 0 A syndrome characterized by bilateral granulomatous UVEITIS with IRITIS and secondary GLAUCOMA, premature ALOPECIA, symmetrical VITILIGO, poliosis circumscripta (a strand of depigmented hair), HEARING [..] [dictionary.university]

Engelsk definition A syndrome characterized by bilateral granulomatous UVEITIS with IRITIS and secondary GLAUCOMA, premature ALOPECIA, symmetrical VITILIGO, poliosis circumscripta (a strand of depigmented hair), HEARING DISORDERS, and meningeal signs [mesh.kib.ki.se]

A syndrome characterized by bilateral granulomatous UVEITIS with IRITIS and secondary GLAUCOMA, premature ALOPECIA, symmetrical VITILIGO, poliosis circumscripta (a strand of depigmented hair), HEARING DISORDERS, and meningeal signs (neck stiffness and [ncbi.nlm.nih.gov]

VKH is a multisystem disorder and includes idiopathic uveitis, dysacousia, leukodermia, alopecia, canities (whitened hair), poliosis (whitened eyebrows and eyelashes), acute encephalitic signs, and fluctuating meningeal symptoms both central and peripheral [jamanetwork.com]

Given that the cutaneous manifestations of VKH disease are so characteristic, these could not have been missed even before the actual clinical entity of VKH was recognized in the early 20th century. [ncbi.nlm.nih.gov]

Vogt-Koyanagi-Harada syndrome is a multisystem disorder characterized by granulomatous panuveitis with exudative retinal detachments that is often associated with neurologic and cutaneous manifestations. [radiopaedia.org]

manifestations, including poliosis, vitiligo, and alopecia. [en.wikipedia.org]

The cutaneous symptoms may lead us to consider diagnostic possibilities such as Alezzandrini's syndrome, alopecia areata, vitiligo and piebaldism 10. [scielo.br]

Besides that, the cutaneous manifestations should exclude diagnosis such as Alezzandrini’s syndrome, alopecia areata, vitiligo and piebaldism. Other immunomediated sensorineural hearing loss should also be excluded such as Cogan syndrome. [doi.org]

Examination of the cerebrospinal fluid reveals a pattern consistent with MENINGITIS, ASEPTIC. [mesh.kib.ki.se]

Examination of the cerebrospinal fluid reveals a pattern consistent with meningitis, aseptic. [icd9data.com]

Definition / general Also called Vogt-Koyanagi-Harada syndrome Rare multisystemic autoimmune disease affecting eyes, meninges, ears and skin Sudden onset of blindness, pleocytosis and temporary hearing loss; no history of eye trauma or surgery (by definition [pathologyoutlines.com]

VKH is a multisystem disorder and includes idiopathic uveitis, dysacousia, leukodermia, alopecia, canities (whitened hair), poliosis (whitened eyebrows and eyelashes), acute encephalitic signs, and fluctuating meningeal symptoms both central and peripheral [jamanetwork.com]

A 29-year-old man presented with headache and decreased vision in his left eye (LE) for 2 days. Best-corrected visual acuity was 20/20 in both his eyes. [ncbi.nlm.nih.gov]

[…] syndrome characterized by bilateral granulomatous UVEITIS with IRITIS and secondary GLAUCOMA, premature ALOPECIA, symmetrical VITILIGO, poliosis circumscripta (a strand of depigmented hair), HEARING DISORDERS, and meningeal signs (neck stiffness and headache [mesh.kib.ki.se]

It is manifested with hearing disorders, panuveitis, alopecia, poliosis, vitiligo, neck stiffness, headaches, and focal neurologic signs ICD-9-CM Volume 2 Index entries containing back-references to 364.24 : [icd9data.com]

The prodromic stage is characterized by nonspecific symptoms such as fever, headaches, nausea and vertigo, and then by neurologic symptoms such as muscle weakness, hemiparesis, hemiplegia, dysarthria and orbital pain. [orpha.net]

There may be fever, headache, nausea, meningismus, dysacusia (discomfort caused by loud noises or a distortion in the quality of the sounds being heard), tinnitus, and/or vertigo. Eye symptoms can include orbital pain, photophobia and tearing. [en.wikipedia.org]

Signs & Symptoms Vogt-Koyanagi-Harada disease is initially characterized by headaches, very deep pain in the eyes, dizziness (vertigo), and nausea. [rarediseases.org]

The prodromic stage is characterized by nonspecific symptoms such as fever, headaches, nausea and vertigo, and then by neurologic symptoms such as muscle weakness, hemiparesis, hemiplegia, dysarthria and orbital pain. [orpha.net]

Initial onset of Vogt-Koyanagi-Harada syndrome is characterized by severe headache, deep pain in the eye, vertigo (feeling that the room is spinning), and nausea, followed in a few weeks by uveitis and vision loss. [healthcentral.com]

In this update, the author cites work that shows that earlier initiation of either glucocorticoids or immunomodulatory measures significantly reduces late visual morbidity in patients with Vogt-Koyanagi-Harada syndrome and that the neurologic manifestations [medlink.com]

Patients must have either the neurologic manifestations or dermatological signs. c. Probable VKH disease: similar eye disease as patients with complete VKH disease but without neurologic and dermatological signs. [rarediseases.org]

manifestation, 054078, 症状, ｼｮｳｼﾞｮｳ, symptom, 040039 [togodb.biosciencedbc.jp]

Complications of the disorder include the following: Cataract Subretinal fibrosis Choroidal neovascularization Neovascularization of the disc Pigmentary changes of the fundus Optic atrophy Neurologic manifestations - Many of the neurologic manifestations [emedicine.com]

Hearing disturbances (75%) and dizziness may also be present. [orpha.net]

Hearing disturbances and dizziness may be present. After weeks or months, most patients notice cutaneous signs (e.g. hair loss, poliosis, vitiligo). [radiopaedia.org]

Signs & Symptoms Vogt-Koyanagi-Harada disease is initially characterized by headaches, very deep pain in the eyes, dizziness (vertigo), and nausea. [rarediseases.org]

The diagnosis of clinical deafness, tinnitus and dizziness should always consider Vogt-Koyanagi-Harada syndrome. [arquivosdeorl.org.br]

The association of HLA-DR4/ HLA-DRB1*04 with VKH was reported in various ethnic populations. Our meta-analysis confirms these previous reports on the association of HLA-DR4/ HLA-DRB1*04 with VKH. [nature.com]

[…] found an association with HLA-DR4 and HLA-DR53, while HLA-DR1 and HLA-DR4 were reported in Hispanic patients living in southern California. [40] An association with HLA-DR4, HLA-DRw53, and HLA-DQw3 has been found in subjects of Native American ancestry [emedicine.com]

VKH has been linked to human leukocyte antigen DR4 (HLA-DR4) and HLA-Dw53, with strongest associated risk for HLA-DRB1*0405 haplotype. [ncbi.nlm.nih.gov]