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Vaginal Sarcoma

Vagina Sarcoma


Presentation

  • CASE: A 34-year-old woman presented with a painful 3-cm left vulvar-vaginal mass, which was excised and determined to be a sarcoma with positive surgical margins.[ncbi.nlm.nih.gov]
  • A bound-in CD-ROM contains all the images from the book, downloadable to PowerPoint presentations.[books.google.it]
  • Consequently they are malignant.2 CLINICAL PRESENTATION: Mostly asymptomatic. Others presenting as a lump near introitus which may cause problems with micturition, defecation or intercourse. Bleeding or discharges are late features. 4.[jemds.com]
  • RESULTS Case 1: A 77-year-old woman with no systemic illnesses presented with a vaginal lump. Clinically, there was a 6-cm… CONTINUE READING[semanticscholar.org]
  • […] in estimating the risk of breast cancer in women from the Indian population Vasu Reddy Challa, Krishnamurthy Swamyvelu and Naran Shetty Abstract Full Article PDF Published: 17 Oct 2013 / Case Report: An unusual case of Waldenstrom’s Macroglobulinemia presented[ecancer.org]
Cyanosis
  • There was no icterus, no clubbing, no cyanosis, no pedal edema. There was no significant lymphadenopathy. Her blood pressure was 120/80 mm Hg and her pulse rate was 72/min. she was afebrile. R.S, C.V.S and C.N.S were clinically normal.[jemds.com]
Vaginal Discharge
  • Vaginal discharge About 10% of women with uterine sarcomas have a vaginal discharge that does not have any visible blood. A discharge is most often a sign of infection or another non-cancer condition, but it also can be a sign of cancer.[cancer.org]
  • Some women have other abnormal vaginal discharge that doesn’t appear to have blood in it.[seattlecca.org]
  • Other symptoms of vaginal cancer include: Abnormal vaginal discharge Difficulty or pain when urinating Pain during sexual intercourse Pain in the pelvic area (the lower part of the abdomen between the hip bones) Pain in the back or legs Swelling in the[cancer.net]
  • discharge dyspareunia Evaluation Biopsy most lesions occur in the upper 1/3 of the vagina Treatment planning should be individualized depending upon the location, size, and clinical stage of the tumor surgery raditation chemotherapy Please rate topic[medbullets.com]
  • discharge or bleeding that is not normal for you.[mcancer.org]
Dyspareunia
  • […] initially be asymptomatic Local pruritus, possibly with burning sensation and pain Reddish, blackish, and/or whitish patches of discoloration Lumps or growths of various shapes, often wart-like lesions or ulcers Vulvar bleeding or discharge Dysuria, dyspareunia[amboss.com]
  • […] grape-like mass in young girls ( 4 years) can prolapse out of vagina spindle-shaped tumor cells stain positive for desmin Presentation Symptoms abnormal vaginal bleeding may be postcoital, intermenstrual, or postmenopausal. watery vaginal discharge dyspareunia[medbullets.com]
  • Painful sexual intercourse or dyspareunia. Pain in the pelvic area. Tumor in the vaginal mucosa.[cancerwall.com]
  • Other symptoms include pain, urinary or rectal symptoms, pruritus, dyspareunia (pain during sexual intercourse), and groin masses. Question the patient about any pain. Assess the use and effectiveness of any analgesics for pain.[medical-dictionary.thefreedictionary.com]

Workup

  • For staging workup, CT- chest was done in the cancer institute. CT -chest was normal. Rhabdomyosarcoma was ruled out as Desmin was negative.[jemds.com]

Treatment

  • Future technologic advances will expand the number of malignancies for which these treatment approaches can be used.[ncbi.nlm.nih.gov]
  • The following are treatment options for sarcoma of the vagina. Your healthcare team will suggest treatments based on your needs and work with you to develop a treatment plan. Surgery You may be offered surgery for sarcoma of the vagina.[cancer.ca]
  • Local recurrences were common for all types of sarcoma in this series, suggesting that more aggressive initial treatment is mandatory if recurrences are to be prevented and the survival rates improved.[ncbi.nlm.nih.gov]
  • Since there was not much of discrimination in the plan of treatment modalities among different types of sarcoma except for rhabdomyosarcoma, the treatment was planned.[jemds.com]
  • CONCLUSIONS: Surgery is the main treatment for primary vaginal sarcoma. Prognosis may be associated with tumor grade and stage. 2015 Japan Society of Obstetrics and Gynecology.[ncbi.nlm.nih.gov]

Prognosis

  • Prognosis may be associated with tumor grade and stage. 2015 Japan Society of Obstetrics and Gynecology.[ncbi.nlm.nih.gov]
  • Primary tumors of the uterus were a distinct group, distinguished from those arising in the vagina by patient age-range and probably by prognosis, as well as site.[ncbi.nlm.nih.gov]
  • The book provides a description at length of the epidemiology, etiology, pathological anatomy, prognosis, diagnosis, differential diagnosis, imaging and comprehensive therapy of each primary, relapsed, and metastasized tumor including surgery, chemo-,[books.google.it]
  • DISCUSSION: Tumors of vagina is generally said to have a very poor prognosis.[jemds.com]

Etiology

  • The book provides a description at length of the epidemiology, etiology, pathological anatomy, prognosis, diagnosis, differential diagnosis, imaging and comprehensive therapy of each primary, relapsed, and metastasized tumor including surgery, chemo-,[books.google.it]
  • In addition to its pathology and genetics, each lesion is described with its epidemiology, etiology, clinical features, as well as prognosis and predictive factors. This book is in the series commonly referred to as the "Blue Book" series.[books.google.es]
  • Vaginal cancer is closely related to vulvar cancer in terms of etiology and histology, but it occurs inside the vagina (typically the posterior third of the vaginal wall), rather than the vulva.[amboss.com]
  • Epidemiology Rare, almost always in postmenopausal women (median age 65 years), small number of women age 40 years Constitutes half of all uterine sarcomas Sites Uterine corpus, cervix, ovaries, fallopian tubes, vagina, peritoneum; also extragenital sites Etiology[pathologyoutlines.com]

Epidemiology

  • Comparing mortality of vaginal sarcoma, squamous cell carcinoma, and adenocarcinoma in the surveillance, epidemiology, and end results database Talayeh Ghezelayagh; Jose Alejandro Rauh-Hain; Whitfield B.[mgh-ita.org]
  • The book provides a description at length of the epidemiology, etiology, pathological anatomy, prognosis, diagnosis, differential diagnosis, imaging and comprehensive therapy of each primary, relapsed, and metastasized tumor including surgery, chemo-,[books.google.it]
  • METHODS: Women with primary invasive vaginal sarcomas, squamous cell carcinomas, and adenocarcinomas diagnosed between 1988 and 2010 were identified within the National Cancer Institute's Surveillance, Epidemiology, and End Results database.[ncbi.nlm.nih.gov]
  • Regulatory Science domains Social determinants Technology & innovation Training & development Prevention & Screening Bioinformatics Biology Biomarkers Causes of cancer Control, survivorships & outcomes Detection, diagnosis & prognosis Devices Diagnostics Epidemiology[ecancer.org]
Sex distribution
Age distribution

Pathophysiology

  • Etiology and Pathophysiology Women with a history of cervical malignancy have a higher probability of developing squamous cell malignancy in the vagina even after hysterectomy.[unboundmedicine.com]
  • PDF Version Xiaodong Feng Anti-Angiogenesis Therapy for Cancer Treatment: An Overview for Clinicians PPT Version PDF Version Muhammad Attique khan Shahid Nuclear Physics PPT Version Aly-Moussa Virology PPT Version PDF Version Sivaramakrishna Koganti Pathophysiological[omicsonline.org]

Prevention

  • Epidemiology & prevention Imaging Screening Treatments Antibodies & immunotherapy Cell therapy & stem cells Complications Cytotoxics Drug development Hormones/endocrine Radiotherapy Supportive care Surgery Targeted molecules Transplantation Vaccines[ecancer.org]
  • Local recurrences were common for all types of sarcoma in this series, suggesting that more aggressive initial treatment is mandatory if recurrences are to be prevented and the survival rates improved.[ncbi.nlm.nih.gov]
  • Clinical trials look at new ways to prevent, find and treat cancer.Find out more about clinical trials .[cancer.ca]
  • […] of HIV HIV Transmission and Prevention in Specific Populations Systematic Review of HIV Behavioral Prevention Research in African Americans Lynae A.[hivinsite.ucsf.edu]
  • Vaccines that prevent some types of HPV infection are available. Exposure to miscarriage prevention drug.[mayoclinic.org]

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