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Vascular Graft Infection


Presentation

  • The usual clinical presentation was back pain. Fever and systemic complaints were usually present.[ncbi.nlm.nih.gov]
  • RESULTS: 32 cases of aortoiliac and aortofemoral vascular graft infection with varied clinical presentation were found.[ncbi.nlm.nih.gov]
  • PURPOSE: To present the use of sartorius myoplasty (SM) and superficial femoral vein (SFV) in a graft-sparing approach to vascular graft infection.[ncbi.nlm.nih.gov]
  • In situ replacement and graft preservation treatments should be selective and based on presentation of the infection and the type of pathogenic organism.[ncbi.nlm.nih.gov]
  • Presented here is a case of M. catarrhalis bacteraemia associated with prosthetic vascular graft infection along with a review of the relevant literature.[ncbi.nlm.nih.gov]
Asymptomatic
  • The patient was asymptomatic and not a surgical candidate, and was treated conservatively with a course of antibiotics.[ncbi.nlm.nih.gov]
  • Eighteen months later (May 2005), the patient was asymptomatic and serology showed persistence of high levels of phase I IgG (1600) and phase II IgG (3200). C. burnetii is a strict intracellular bacterium.[bmcinfectdis.biomedcentral.com]
  • Presentation Unfortunately the presentation for an endoleak is usually completely asymptomatic. 5 However, remember that any patient undergoing endovascular repair can have as high as a 25% postoperative complication rate.[emdocs.net]
Italian
  • SETTING: A single department of vascular surgery and one of nuclear medicine of a Northern Italian hospital.[ncbi.nlm.nih.gov]
  • A Journal on Vascular and Endovascular Surgery Official Journal of the Italian Society of Vascular and Endovascular Surgery Indexed/Abstracted in: EMBASE, Emerging Sources Citation Index, Scopus eTOC ORIGINAL ARTICLES Copyright 2006 EDIZIONI MINERVA MEDICA[minervamedica.it]
Recurrent Infection
  • Morbidity and mortality associated with treatment, likelihood of long-term limb salvage, and likelihood of persistent or recurrent infection vary among these types of treatment.[ncbi.nlm.nih.gov]
  • At 2.4 years mean follow-up, the incidence of graft infection was 0.66% (6 early and 7 late); 1 patient presented infection in 2 sites and 1 patient had 2 recurrent infections. The mean time between graft insertion and infection was 6.6 months.[minervamedica.it]
Fulminant Sepsis
  • In some patients primary amputation after graft infection was necessary to prevent further deterioration with fulminant sepsis. The overall mortality was 17%, the amputation rate was 60%.[ncbi.nlm.nih.gov]
Night Sweats
  • A 53-year-old man with a past medical history of total arch replacement surgery and severe aortic regurgitation presented with a 1-month history of persistent general malaise, anorexia, body weight loss and night sweats.[ncbi.nlm.nih.gov]
Foot Ulcer
  • New Third Edition chapters cover bioterrorism, hospital infections, emerging infections, Kawasaki syndrome, transmissible spongiform encephalopathies, diabetic foot ulcers, decubitus ulcers, staphylococcal and streptococcal toxic shock syndrome, food[books.google.com]
Withdrawn
  • (Although safety was not an issue in this investigation, following reports of serious, including two fatal, events after administration, 99mTc-fanolesomab was withdrawn from the United States market).[ncbi.nlm.nih.gov]
  • (Although safety was not an issue in this investigation, following reports of serious, including two fatal, events after administration, 99m Tc-fanolesomab was withdrawn from the United States market.)[journals.lww.com]

Workup

  • The diagnostic workup revealed an infected vascular graft that had been implanted 2 years before because of a ruptured infrarenal aortic aneurysm as the cause of HOA.[ncbi.nlm.nih.gov]
  • We present a case of an 83-year-old man, who had an F-18 FDG PET/CT scan for workup of a solitary pulmonary nodule, and was incidentally diagnosed with chronic multifocal infection of an aorto-iliac vascular graft, with an infected fistula tract into[ncbi.nlm.nih.gov]
  • […] number of infected grafts was small, CT is recommended as the initial examination when graft infection is suspected because it can be performed immediately. 67Ga scintigraphy remains an important complementary test, adding specificity to the diagnostic workup[ncbi.nlm.nih.gov]
  • Don’t be hesitant to get a vascular surgeon involved even if your workup is normal. References / Further Reading Chenu C, Marcheix B, Barcelo C, Rousseau H.[emdocs.net]
Coxiella Burnetii
  • We report the first case of Coxiella burnetii vascular graft infection diagnosed by broad-range PCR and discuss the diagnostic approaches and treatment strategies of chronic C. burnetii infection.[ncbi.nlm.nih.gov]
  • BACKGROUND: Q fever is considered endemic worldwide, and endocarditis, or aortic vascular infection, or both caused by Coxiella burnetii can be a fatal disease. The importance of surgical intervention has not yet been defined.[ncbi.nlm.nih.gov]
  • Coxiella burnetii, the causative agent of Q fever, may cause culture-negative vascular graft infections that can be diagnosed by serology and molecular biology.[ncbi.nlm.nih.gov]
  • View Article Google Scholar Georghiou GP, Hirsch R, Vidne BA, Raanani E: Coxiella burnetii infection of an aortic graft: surgical view and a word of caution.[bmcinfectdis.biomedcentral.com]
  • We present a case of overt gastrointestinal bleeding from an aortoesophageal fistula in a patient with chronic infection of an endovascular prosthesis with Coxiella burnetii .[acgcasereports.gi.org]
Chlamydia
  • […] complete coverage of newer viruses such as human herpesvirus 6 and 8, West Nile virus, hepatitis C, D, and E, hantaviruses, caliciviruses, and astroviruses, as well as recently discovered microorganisms such as Escherichia coli 0157, Helicobacter pylori, Chlamydia[books.google.com]

Treatment

  • , auxiliary diagnostic methods, antibiotic treatment, anti-infective structures of vascular prostheses, surgical treatment, treatment strategy against infectious aortic aneurysms, future surgical treatment, postoperative systemic therapy, and antimicrobial[ncbi.nlm.nih.gov]
  • Morbidity and mortality associated with treatment, likelihood of long-term limb salvage, and likelihood of persistent or recurrent infection vary among these types of treatment.[ncbi.nlm.nih.gov]
  • Abstract Debate continues over which procedure is the best treatment for prosthetic graft infections.[ncbi.nlm.nih.gov]
  • The options for surgical treatment are not uniformly accepted and remain controversial.[ncbi.nlm.nih.gov]
  • We performed a descriptive retrospective study to assess indications for surgical treatment, timing of treatment, and outcome.[ncbi.nlm.nih.gov]

Prognosis

  • CONCLUSION: Avidin/111In-biotin scintigraphy is a simple and accurate imaging method for the routine diagnosis of vascular graft infection, and it may have a role in identifying the disease process in its initial stages, thus improving prognosis.[ncbi.nlm.nih.gov]

Etiology

  • C. burnetii should be considered as etiological agent in patients with a vascular graft and fever, abdominal pain, and laboratory signs of inflammation, with or without exposure history.[ncbi.nlm.nih.gov]
  • This report emphasizes the relevance of the PET scanner in the diagnosis of infection when used in association with Q fever serology and molecular biology for the etiological identification of C. burnetii.[ncbi.nlm.nih.gov]
  • Conclusion C. burnetii should be considered as etiological agent in patients with a vascular graft and fever, abdominal pain, and laboratory signs of inflammation, with or without exposure history.[bmcinfectdis.biomedcentral.com]
  • Bulgaria 2 Department of Microbiology and Medical Genetics, Bulgaria 3 Student, Faculty of Medicine Medical University - Pleven, Bulgaria Abstract PDF References Article Recommendations Summary The purpose of the study was to evaluate the frequency and etiology[degruyter.com]
  • Etiology and Anatomic Pathology of Thoracic Outlet Syndrome 56. Diagnosis of Thoracic Outlet Syndrome 57. Conservative Treatment for Thoracic Outlet Syndrome 58. Transaxillary Operative Management of Thoracic Outlet Syndrome 59.[euro-libris.ro]

Epidemiology

  • Furthermore, because of the changed epidemiology of bacterial susceptibility against antibiotics today, reliance on the efficacy of systemic antibiotic prophylaxis must be done with caution.[ncbi.nlm.nih.gov]
  • Expected value of the project: Results from the proposed study are an important contribution to the field, based on the large sample size, longitudinal design and by unifying clinical and epidemiological science.[clinicaltrials.gov]
  • PhD 1 , Stefan P Kuster, MD MSc 1 , Alexandra U Scherrer, PhD 1 , Bettina Näf, cand.med. 1 , Reinhard Zbinden, MD 2 , Zoran Rancic, MD PhD PD 3 , Dominique Bettex, MD 4 , Mario Lachat, MD 3 and Barbara Hasse, MD 1 , (1)Infectious Diseases and Hospital Epidemiology[idsa.confex.com]
  • Vascular graft infections: epidemiology, microbiology, pathogenesis and prevention. In: Towne JB and Hallier LH, editors. Complications in Vascular Surgery. 6th ed. New York: Marcel Dekker Inc; 2004. p. 305-16. 6. Calligaro KD, Veith FJ.[degruyter.com]
  • Miler , MA , Herwaldt , LA : Laboratory, clinical, and epidemiological aspects of coagulase-negative staphylococci . Clinical Microbiology Review. 1988 ; 1 : 281 – 299 . 5.[cambridge.org]
Sex distribution
Age distribution

Pathophysiology

  • Moreover, since VGIs demonstrate very specific pathophysiology, guidelines on other material-related infections or infective endocarditis treatment cannot be entirely applied to VGI.[ncbi.nlm.nih.gov]
  • Pathophysiology of Aortic Dissections 69. Arteriomegaly and Aneurysmosis 70. Vascular complications of Marfan syndrome, Ehlers-Danlos Syndrome and Loeys-Dietz Syndrome 71. Ultrasonography in the Evaluation of Abdominal Aortic Aneurysms 72.[euro-libris.ro]

Prevention

  • Specific emphasis is put on silver and its use in antimicrobial vascular grafts for prevention and treatment of vascular surgical infection. Copyright 2011 Elsevier Inc. All rights reserved.[ncbi.nlm.nih.gov]
  • Therefore, LVFX-ALB presumably had a bactericidal action and adhesive prevention against inoculated S. aureus. LVFX-ALB may be useful in preventing graft infections during and immediately after vascular reconstruction.[ncbi.nlm.nih.gov]
  • A thorough understanding of these issues will enable us to prevent prosthetic vascular graft infection in the thoracic aortic area as far as possible.[ncbi.nlm.nih.gov]
  • Dental-type antibiotic prophylaxis would not have prevented any of the infections in this study. Aggressive treatment of recognized sources of infection in patients with vascular grafts is imperative.[ncbi.nlm.nih.gov]
  • Sound surgical technique, use of prophylactic antibiotics and the avoidance of a groin incision are emphasized as the most important factors in prevention of graft infection.[ncbi.nlm.nih.gov]

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