Presentation
The usual clinical presentation was back pain. Fever and systemic complaints were usually present. [ncbi.nlm.nih.gov]
Entire Body System
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Anorexia
A 53-year-old man with a past medical history of total arch replacement surgery and severe aortic regurgitation presented with a 1-month history of persistent general malaise, anorexia, body weight loss and night sweats. [ncbi.nlm.nih.gov]
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Fulminant Sepsis
In some patients primary amputation after graft infection was necessary to prevent further deterioration with fulminant sepsis. The overall mortality was 17%, the amputation rate was 60%. [ncbi.nlm.nih.gov]
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Intravenous Drugs
An infectious aneurysm can result from infections in other parts of the body, blood vessel trauma from catheterization, traumatic injury or intravenous drug use. [news.heart.org]
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Fever of Unknown Origin
“Months to even years later, people who have undergone an abdominal aneurysm repair can develop a fever of unknown origin with bacteria in the bloodstream. [news.heart.org]
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Difficulty Walking
PAD typically causes narrowing of the leg arteries, resulting in pain and difficulty walking. If left untreated, PAD can lead to gangrene and amputation of a limb. [news.heart.org]
Psychiatrical
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Suggestibility
Later on an 18F-FDG PET/CT study showed a pathological uptake, suggestive of periprosthetic infection, as well as an incidental pulmonary lesion, suggestive of a primary neoplasm. [ncbi.nlm.nih.gov]
Workup
The diagnostic workup revealed an infected vascular graft that had been implanted 2 years before because of a ruptured infrarenal aortic aneurysm as the cause of HOA. [ncbi.nlm.nih.gov]
Don’t be hesitant to get a vascular surgeon involved even if your workup is normal. References / Further Reading Chenu C, Marcheix B, Barcelo C, Rousseau H. [emdocs.net]
Microbiology
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Coxiella Burnetii
We report the first case of Coxiella burnetii vascular graft infection diagnosed by broad-range PCR and discuss the diagnostic approaches and treatment strategies of chronic C. burnetii infection. [ncbi.nlm.nih.gov]
View Article Google Scholar Georghiou GP, Hirsch R, Vidne BA, Raanani E: Coxiella burnetii infection of an aortic graft: surgical view and a word of caution. [bmcinfectdis.biomedcentral.com]
We present a case of overt gastrointestinal bleeding from an aortoesophageal fistula in a patient with chronic infection of an endovascular prosthesis with Coxiella burnetii. [acgcasereports.gi.org]
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Chlamydia
[…] complete coverage of newer viruses such as human herpesvirus 6 and 8, West Nile virus, hepatitis C, D, and E, hantaviruses, caliciviruses, and astroviruses, as well as recently discovered microorganisms such as Escherichia coli 0157, Helicobacter pylori, Chlamydia [books.google.com]
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Human Herpesvirus 6
This edition provides complete coverage of newer viruses such as human herpesvirus 6 and 8, West Nile virus, hepatitis C, D, and E, hantaviruses, caliciviruses, and astroviruses, as well as recently discovered microorganisms such as Escherichia coli 0157 [books.google.com]
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Helicobacter Pylori
pylori, Chlamydia pneumoniae, Bartonella, and microsporidia. [books.google.com]
Treatment
auxiliary diagnostic methods, antibiotic treatment, anti-infective structures of vascular prostheses, surgical treatment, treatment strategy against infectious aortic aneurysms, future surgical treatment, postoperative systemic therapy, and antimicrobial [ncbi.nlm.nih.gov]
Prognosis
CONCLUSION: Avidin/111In-biotin scintigraphy is a simple and accurate imaging method for the routine diagnosis of vascular graft infection, and it may have a role in identifying the disease process in its initial stages, thus improving prognosis. [ncbi.nlm.nih.gov]
In conclusion, abdominal-aortic, thoracic-aortic, and peripheral PVGI are three quite distinct clinical entities and the prognosis for treatment of a PVGI seems to be influenced by the location of the PVGI. [journals.plos.org]
Etiology
C. burnetii should be considered as etiological agent in patients with a vascular graft and fever, abdominal pain, and laboratory signs of inflammation, with or without exposure history. [ncbi.nlm.nih.gov]
Conclusion C. burnetii should be considered as etiological agent in patients with a vascular graft and fever, abdominal pain, and laboratory signs of inflammation, with or without exposure history. [bmcinfectdis.biomedcentral.com]
Bulgaria 2 Department of Microbiology and Medical Genetics, Bulgaria 3 Student, Faculty of Medicine Medical University - Pleven, Bulgaria Abstract PDF References Article Recommendations Summary The purpose of the study was to evaluate the frequency and etiology [degruyter.com]
Epidemiology
Furthermore, because of the changed epidemiology of bacterial susceptibility against antibiotics today, reliance on the efficacy of systemic antibiotic prophylaxis must be done with caution. [ncbi.nlm.nih.gov]
Expected value of the project: Results from the proposed study are an important contribution to the field, based on the large sample size, longitudinal design and by unifying clinical and epidemiological science. [clinicaltrials.gov]
Ledergerber, PhD 1, Stefan P Kuster, MD MSc 1, Alexandra U Scherrer, PhD 1, Bettina Näf, cand.med. 1, Reinhard Zbinden, MD 2, Zoran Rancic, MD PhD PD 3, Dominique Bettex, MD 4, Mario Lachat, MD 3 and Barbara Hasse, MD 1, (1)Infectious Diseases and Hospital Epidemiology [idsa.confex.com]
Vascular graft infections: epidemiology, microbiology, pathogenesis and prevention. In: Towne JB and Hallier LH, editors. Complications in Vascular Surgery. 6th ed. New York: Marcel Dekker Inc; 2004. p. 305-16. 6. Calligaro KD, Veith FJ. [degruyter.com]
Miler, MA, Herwaldt, LA : Laboratory, clinical, and epidemiological aspects of coagulase-negative staphylococci. Clinical Microbiology Review. 1988 ; 1 : 281 – 299. 5. [cambridge.org]
Pathophysiology
Moreover, since VGIs demonstrate very specific pathophysiology, guidelines on other material-related infections or infective endocarditis treatment cannot be entirely applied to VGI. [ncbi.nlm.nih.gov]
Prevention
Specific emphasis is put on silver and its use in antimicrobial vascular grafts for prevention and treatment of vascular surgical infection. Copyright 2011 Elsevier Inc. All rights reserved. [ncbi.nlm.nih.gov]