Presentation
We concluded that endothelium-dependent vasodilation evoked with substance P was present at the site where coronary vasospasm occurred spontaneously in our case. [ncbi.nlm.nih.gov]
CardioCase presentation. Ethel s Case. [docplayer.net]
Entire Body System
- Pain
This may exacerbate unwanted venous pooling during postoperative pain therapy. [ncbi.nlm.nih.gov]
Chest Pain Chest pain is a common complaint by a patient in the ER. [medicinenet.com]
- Congestive Heart Failure
This case is unusual in that hypotension, as opposed to hypertension, was a consequence of increased sympathetic tone in the postoperative period, but it illustrates the well known fact that patients in compensated congestive heart failure do poorly when [ncbi.nlm.nih.gov]
heart failure who have dyspnea at rest or with minimal activity.DB05794SerelaxinInvestigated for use/treatment in cardiovascular disorders, congestive heart failure, infertility, peripheral vascular disease, and scleroderma.DB06154Pentaerythritol tetranitrateUsed [drugbank.ca]
heart failure and 21 normal subjects. [jci.org]
- Weakness
[…] in your hands or feet Swollen feet, lower legs, or lymph nodes Bloating Fever and sore throat Weakness Skin rash or redness, itching, or blisters; or unusual changes in the way your skin looks Constipation Dizziness or lightheadedness Fainting [saintlukeskc.org]
An aneurysm is a weakness in an artery wall. This weakness in the wall causes the artery to widen or balloon out, and then they rupture or break open. A person with an brain aneurysm generally won't have any symptoms until it becomes a problem. [medicinenet.com]
- Fever
Prostaglandins could ease inflammation, fever and pain, and tothrombozne A2 could lead to formation of blood clots. [en.wikibooks.org]
When to call your healthcare provider Call your healthcare provider right away if you have any of the following: Chest, muscle, or joint pain Pain, numbness, tingling, or weakness in your hands or feet Swollen feet, lower legs, or lymph nodes Bloating Fever [saintlukeskc.org]
Abstract Coxiella burnetii is an intracellular bacterial pathogen that causes human Q fever, an acute flu-like illness that can progress to chronic endocarditis and liver and bone infections. [ncbi.nlm.nih.gov]
If you get any of these, contact your doctor right away: Fever Joint or chest pain Sore throat Skin rash (especially on the face) Unusual bleeding or bruising Weight gain Swelling of the ankles Other Guidelines for Vasodilators While taking them, have [webmd.com]
In particular, avoiding over-the-counter medicines for appetite control, colds, cough, sinus problems, asthma, hay fever and other allergies, should be avoided as these may increase blood pressure. [encyclopedia.com]
- Fatigue
Vasodilation also helps improve the removal of catabolic waste products from the muscles like lactic acid and ammonia that contribute to muscle fatigue and failure. [atpextreme.com]
This can cause you to feel fatigued, have a headache or experience stomach upset. Caffeine affects people differently. [livestrong.com]
Nausea, vomiting, malaise, indigestion, sweating, shortness of breath, and fatigue may signal a heart attack. [medicinenet.com]
Gastrointestinal
- Diarrhea
Mild side effects include: Headache Nausea or vomiting Diarrhea Loss of appetite When to call your healthcare provider Call your healthcare provider right away if you have any of the following: Chest, muscle, or joint pain Pain, numbness, tingling, or [saintlukeskc.org]
Headache ; rapid, irregular, or pounding heartbeat; numbness or tingling of the fingers or toes; lightheadedness or passing out; loss of appetite; and diarrhea : Your doctor probably will prescribe more medicine to control these. [webmd.com]
Side Effects of Vasodilator Drugs Side effects of vasodilator drugs are just temporary like as follows: Loss of appetite Diarrhea Headache Nausea or vomiting It is to be noted that the patients who are taking vasodilators shouldn't take any other medicines [pharmaceutical-drug-manufacturers.com]
This effect explains diarrhea observed in patients with carcinoid syndrome. Serotonin has an emetic effect by stimulation of 5-HT3 receptors. [pharmacorama.com]
- Constipation
Calcium channel blockers may also cause headaches, swelling of the feet, exacerbation of heart burn, constipation, gum overgrowth, nausea and constipation. In older patients it can exacerbate eczema and dry skin. [rheumaderm-society.org]
[…] muscle, or joint pain Pain, numbness, tingling, or weakness in your hands or feet Swollen feet, lower legs, or lymph nodes Bloating Fever and sore throat Weakness Skin rash or redness, itching, or blisters; or unusual changes in the way your skin looks Constipation [saintlukeskc.org]
[…] seek medical help immediately: hives swelling in lips, face, throat or tongue difficulty breathing chest pain vision problems bloody vomit nausea fever jaundice (yellow skin or eyes) convulsions Less severe symptoms can include: upset stomach diarrhea constipation [en.wikibooks.org]
Additionally to these, male patients may experience impotence. [18] clonidine hydrochloride guanabenz acetate guanfacine hydrochloride Clonidine, guanabenz or guanfacine may give rise to severe dryness of the mouth, constipation or drowsiness. [en.wikipedia.org]
Cardiovascular
- Hypertension
Portopulmonary hypertension (POPH) is a part of group 1 pulmonary hypertension (pulmonary hypertension associated with portal hypertension). [ncbi.nlm.nih.gov]
The Journal of Clinical Hypertension. 2011;13(9):690-692. ↑ Carter B, Saseen J. Hypertension. 5th ed. New York, NY: McGraw-Hill; 2002. ↑ Patel P, Jneid H. Interventional Pharmacology-Vasodilators. [physio-pedia.com]
Another type of indirect mechanism is the… Read More treatment of hypertension In hypertension: Treatment Vasodilators act by relaxing smooth muscle in the walls of blood vessels, allowing small arteries to dilate and thereby decreasing total peripheral [britannica.com]
Usage of Vasodilators • Systemic hypertension • Heart failure • Peripheral vascular disease • Raynaud's disease • Pulmonary hypertension. 3. Directly acting vasodilators : 1. [slideshare.net]
- Hypotension
Adverse effects : • Hypotension • Raised serum creatinine. • Headache. 31. [slideshare.net]
HYD/ISDN dosing was progressively and consistently decreased up to the moment of hospital discharge and during outpatient follow-up, primarily due to incident hypotension. [ncbi.nlm.nih.gov]
- Heart Disease
Abstract The operability of congenital heart disease with left to right shunt depends on the severity of the pulmonary vascular disease induced by the increased pulmonary blood flow. [ncbi.nlm.nih.gov]
Heart Disease Heart disease (coronary artery disease) occurs when plaque builds up in the coronary arteries, the vessels that supply blood to the heart. Heart disease can lead to heart attack. [medicinenet.com]
- Tachycardia
Ischaemia induced ventricular arrhythmia (bursts of polymorphous tachycardia) that responded well to antispastic therapy. [ncbi.nlm.nih.gov]
The vasodilation may cause reflex tachycardia, orthostatic hypotension, and nasal congestion. [accessanesthesiology.mhmedical.com]
ADVERSE EFFECTS OF HYDRALAZINE CNS: Headache Dizziness Peripheral neuropathy CVS: Palpitation Flushing Reflex tachycardia Angina Ischemic arrhythmias GIT: Anorexia Nausea. [slideshare.net]
Possible side effects of taking vasodilators include flushing, headache, dizziness, fainting, nausea, swollen ankles, chest pain, rapid heartbeat (tachycardia), and heart palpitations. Other medications may be prescribed to counter these effects. [daviddarling.info]
Reflex tachycardia is the primary adverse effect of these drugs, as a consequence of the medication induced baroreflex response compensating for the sudden medication decrease in vascular resistance. [physio-pedia.com]
- Orthostatic Hypotension
hypotension can often occur owing to systemic vasodilatation. [ncbi.nlm.nih.gov]
Other less serious side effects include orthostatic hypotension, dizziness, weakness, fluid retention and nausea.[6] PTs should be mindful of potential implications of adverse effects of these drugs or contraindications to therapy in patients. [physio-pedia.com]
The vasodilation may cause reflex tachycardia, orthostatic hypotension, and nasal congestion. [accessanesthesiology.mhmedical.com]
Examples include: [ citation needed ] Endogenous [ edit ] Vasoconstriction is a procedure of the body that averts orthostatic hypotension. [en.wikipedia.org]
Vasodilators can impair normal baroreceptor-mediated reflex vasoconstriction when a person stands up, which can lead to orthostatic hypotension and syncope upon standing. [cvpharmacology.com]
Psychiatrical
- Withdrawn
[…] angina in coronary artery disease.DB01020Isosorbide mononitrateA nitrate used to prevent and treat angina and to treat angina caused by coronary artery disease.DB01613Erythrityl tetranitrateFor the prevention of angina.DB04825PrenylaminePrenylamine was withdrawn [drugbank.ca]
The vasodilators were withdrawn and, using a crossover design all patients received carprazidil (mean final dose 88 mg) and minoxidil (20 mg) for an average period of 5 to 6 months. [link.springer.com]
Six-month effects of early treatment with lisinopril and transdermal glyceryl trinitrate singly and together withdrawn 6 weeks after acute myocardial infarction. The GISSI-3 trial. J Am Coll Cardiol 1996;27:337-44. [ Links ] 28. [scielo.org.mx]
Antihypertensive medication was withdrawn 48 h before the beginning of the study. HD patients were studied in the morning during their short dialysis-free interval. Their actual weight did not exceed the estimated dry weight by >2 kg. [jasn.asnjournals.org]
[…] repeated sampling before and 24 hr after SAC (days 18 and 19) after a two week period of regular inhaled β 2 -agonist (albuterol) or placebo, and final repeat sampling (day 25) of initial lung segments after 1 additional week of β 2 -agonist or placebo, withdrawn [respiratory-research.biomedcentral.com]
- Fear
Most is due to fear that the exertion of sexual activity will precipitate another myocardial infarction, but 10% to 15% is due to organic causes of impotence. 4 Approximately 5.5 million men take nitrates on a regular basis for angina pectoris, 5 and [circ.ahajournals.org]
Urogenital
- Renal Injury
Bosch: Outcome of Acute Renal Injury in Diabetic Mice with Experimental Endotoxemia: Role of Hypoxia-Inducible Factor-1α.Journal of Diabetes Research Volume 2013, Article ID 254529, ( http://dx.doi.org/10.1155/2013/254529 ) Ortega, M. Romero, A. [cifra2-cm.com]
Workup
T Wave
- T Wave Inversion
[…] patients on minoxidil It's unclear if minoxidil causes pericardial effusions since it is often used in patients with other risk factors for effusions (e.g. kidney disease) [1] EKG changes Minoxidil can cause changes on the electrocardiogram (EKG or ECG) T-wave [straighthealthcare.com]
Treatment
We investigated the correlation between the type of audiometric curve and hearing gain after treatment, the correlation between the age and the effectiveness of treatment, plus the effect of therapy on tinnitus. [ncbi.nlm.nih.gov]
Another type of indirect mechanism is the… Read More treatment of hypertension In hypertension: Treatment Vasodilators act by relaxing smooth muscle in the walls of blood vessels, allowing small arteries to dilate and thereby decreasing total peripheral [britannica.com]
Previous studies have indicated that short-term survival can be enhanced by vasodilator treatment. [dictionary.cambridge.org]
Prognosis
Primary pulmonary hypertension is a rare disease of childhood, which carries a poor prognosis. Patients often present with severe exercise limitation, and untreated life expectancy is less than 1 year. [ncbi.nlm.nih.gov]
Low frequency, either too low or too high loudness and complete maskability of tinnitus indicated a good prognosis with vasodilators. [link.springer.com]
Etiology
Penile duplex Doppler ultrasound (PDDU) assesses the etiology of erectile dysfunction. Peak systolic velocity (PSV), end-diastolic velocity (EDV), and resistive index (RI) are common PDDU parameters. [ncbi.nlm.nih.gov]
New concept in etiology and managment of otologic aspects. Transactions of the American Academy of Ophthalmology and Otolaryngology, 58 : 529–531. Google Scholar 5. Lempert J. (1946): Tympanosympathectomy. Archives of Otolaryngology, 43 : 199–212. [link.springer.com]
[…] dynamic than aortic regurgitation, experimental studies have shown that the aortic regurgitant orifice area decreases during diastole and also depends on the loading conditions. 2 Clearly, changes in the regurgitant orifice area are associated with the etiology [revespcardiol.org]
Clinical Characteristics of Patients With Asymptomatic C~UXI~C A&c Regu~git~tj~~ Treated With En&+\ and ~y~ra~~z~ne Age Cvr) Gender (M/F) Duration of AR (yr)* Mean severity of AR Mild/moderate/severe With SBP ~180 mm Hg Etiology Thickened/degenerative [fdocuments.in]
Epidemiology
Although some recommendations exist regarding operative indications according to pathological, hemodynamic, and epidemiological factors, the evidence underlying these recommendations is not conclusive. [ncbi.nlm.nih.gov]
Abstract Introduction Epidemiological studies have found populations living at higher elevations are at lower risk for acute myocardial infarction (MI) than those at lower elevations, even after adjustments for confounders. [fasebj.org]
PEACOCK: Yes, your epidemiology comments are quite accurate: we did start in the heart-transplant world, and as the Acute Decompensated Heart Failure National Registry (ADHERE) registry 1 showed us, HF is slightly common in women—just over half of the [themedicalroundtable.com]
Use of blood pressure lowering drugs in the prevention of cardiovascular disease: meta-analysis of 147 randomised trials in the context of expectations from prospective epidemiological studies. [futuremedicine.com]
Many epidemiologic studies have studied the relationship between coffee consumption and the risk of heart disease. [hindawi.com]
Pathophysiology
Author information 1 a Department of Pathology and Pathophysiology, Hubei Provincial Key Laboratory of Developmentally Originated Disease, Wuhan University School of Basic Medical Sciences, Wuhan, Hubei, China. 2 b Division of Nephrology, Renmin Hospital [ncbi.nlm.nih.gov]
In between, you have the other pathophysiologic state of pulmonary venous congestion. Such patients clearly benefit from venodilators, and we are reminded of the article from 1931 by Dr. [themedicalroundtable.com]
Página 133 - Cines, DB, Pollak, ES, Buck, CA, Loscalzo, J., Zimmerman, GA, McEver, RP, Pober, JS, Wick, TM, Konkle, BA, Schwartz, BS, Barnathan, ES, McCrae, KR, Hug, BA, Schmidt, AM, and Stern, DM (1998) Endothelial cells in physiology and in the pathophysiology [books.google.es]
However, therapies with unequivocal benefit in HFrEF have failed to show efficacy in HFpEF (3–5), suggesting important pathophysiologic differences. [onlinejacc.org]
Prevention
Among the three prevention groups, the combination group had the most efficient results. In conclusion, the combined prevention with an anticoagulant and a vasodilator has the potential to decrease the incidence of steroid-associated ONFH in rabbits. [ncbi.nlm.nih.gov]
[…] coronary artery disease.DB01020Isosorbide mononitrateA nitrate used to prevent and treat angina and to treat angina caused by coronary artery disease.DB01613Erythrityl tetranitrateFor the prevention of angina.DB04825PrenylaminePrenylamine was withdrawn [drugbank.ca]
Heart Attack Prevention Heart disease and heart attacks can be prevented by leading a healthy lifestyle with diet, exercise, and stress management. [medicinenet.com]