Any unexplained weight gain needs prompt professional medical advice.more ». Any unexplained weight gain needs prompt professional medical advice. [etalger.org]

He showed normal weight gain and head circumference, which had not been described previously. Hematologic and molecular studies of the patient excluded the thalassemia trait or Hb H disease. [omim.org]

Patients present with short stature, generalized obesity, hypotonia, mental retardation, abnormal cry, and seizures. [accessanesthesiology.mhmedical.com]

crawling, walking), hypotonia, delayed bone growth and severe failure to thrive are the main characteristics of this disorder. [accessanesthesiology.mhmedical.com]

Clinical features can include various anomalies, including craniofacial (narrow forehead, up-slanted fissures, brachycephaly, microphthalmia, narrow palate, bifid uvula), orthopedic (kyphoscoliosis, camptodactyly, genu valgum, proximally set thumb, ulna [accessanesthesiology.mhmedical.com]

Four had small head, with narrow forehead in two. History of neonatal hypotonia with difficulty in feedings was obtained in two. A variety of structural abnormalities of the hand and other skeletal defects were observed in some. [nature.com]

Clinical features can include various anomalies, including craniofacial (narrow forehead, up-slanted fissures, brachycephaly, microphthalmia, narrow palate, bifid uvula), orthopedic (kyphoscoliosis, camptodactyly, genu valgum, proximally set thumb, ulna [accessanesthesiology.mhmedical.com]

Other clinical features include microcephaly, prominent supraorbital ridges, ptosis, unusually deep-set eyes, and/or a short neck. An X-linked dominant or recessive genetic trait has been suggested. [accessanesthesiology.mhmedical.com]

Clinical Features Smith et al. (1980) described 2 brothers with a combination of mental retardation, microcephaly, short stature, and unusual facial appearance, including slanted palpebral fissures, narrow face with maxillary overjet, alternating exotropia [omim.org]

Symptoms - Vasquez Hurst Sotos syndrome * Mental retardation * Mild skeletal defects * Deafness * Concentration difficulties * Learning difficulties * Dysmorphic facies * Hypogonadism * Hypotonic facies * Renal anomalies * Incomplete development of genitals [checkorphan.org]

familial developmental Dysphasia, familial developmental MedGen Managing Gastric Linitis Plastica: Keep the scalpel sheathed Managing Gastric Linitis Plastica: Keep the scalpel sheathed Sultan Qaboos University Medical Journal. 2013 Aug; 13(3)451 Peripheral [ncbi.nlm.nih.gov]

Liver function studies, liver biopsy, and serum iron and iron-binding capacity will help rule out hemochromatosis and cirrhosis of the liver. [checkorphan.org]