Herein, we report the unusual presentation of venlafaxine withdrawal in a female preterm baby of 29 weeks gestation, who presented with myoclonic seizures on her second day of life. [ncbi.nlm.nih.gov]

• Fatigue

  As for the short-acting selective serotonin re-uptake inhibitors, severe discontinuation reactions may occur with venlafaxine, seemingly marked most distinctly by headache, nausea, fatigue, dizziness and dysphoria, and may make cessation of the drug extremely [ncbi.nlm.nih.gov]

  Some of the other most common side effects include brain zaps, nausea, weight gain and fatigue or feeling tired. It is important to always speak with your doctor before taking effexor or any other antidepressant. [web.archive.org]

  […] is prescribed to treat Depression Social phobia Anxiety Panic disorders Hot flashes (menopause and breast cancer therapy related) Diabetic neuropathy pain Post-traumatic stress disorder Tension type headaches and migraines Bipolar depression Chronic fatigue [newhealthadvisor.com]

• Hyperthermia

  Serotonin syndrome is characterized by rapid development of hyperthermia, hypertension, myoclonus, rigidity, autonomic instability, mental status changes (e.g., delirium or coma), and in rare cases, death. [pdr.net]

  Of the 7 deaths, 4 people had significant hyperthermia. There was a statistically significant increased risk of death associated with stimulant exposure. [ncbi.nlm.nih.gov]

• Movement Disorder

  Drug-Induced Tremor [ hide all summaries ] (July 2018) Tremor is the single most common movement disorder, affecting millions of people in the U.S. If you have tremors, could one of your drugs be the cause? Read this article to learn the answer. [worstpills.org]

  Case reports documenting an interaction between metoclopramide and other serotonergic agents (i.e., SSRIs) suggest that serotonin syndrome and/or movement disorders are possible during combined use of metoclopramide and SNRIs. [pdr.net]

• Veterinarian

  A: Supply once with a prescription from a doctor or veterinarian B: Supply with a prescription from a doctor or veterinarian C: Supply on technical advice from medical staff D: Supply on technical advice E: Supply without technical advice デンマーク [ 編集 ] [ja.wikipedia.org]

• Nausea

  Poor drug metabolizer, lower dose requirements, nausea, vomiting and diarrhea Details Cytochrome P450 2D6 CYP2D6*11 Not Available 883G>C Effect Inferred Poor drug metabolizer, lower dose requirements, nausea, vomiting and diarrhea Details Cytochrome [drugbank.ca]

  As for the short-acting selective serotonin re-uptake inhibitors, severe discontinuation reactions may occur with venlafaxine, seemingly marked most distinctly by headache, nausea, fatigue, dizziness and dysphoria, and may make cessation of the drug extremely [ncbi.nlm.nih.gov]

  Headache, insomnia, and nausea were among the most common adverse effects. This systematic review provides preliminary support that venlafaxine may have short term utility in treating ADHD in children and adolescents. [doi.org]

• Hypertension

  Hypertension 53:631–638 View Article Google Scholar Pardal PK, John TR, Rathee SP (2001) Venlafaxine induced hypertension: a case report. [doi.org]

  Venlafaxine must be discontinued if significant hypertension persists. [ncbi.nlm.nih.gov]

  […] is controlled in line with the current NICE guideline on hypertension. [gpnotebook.co.uk]

  Stay alert for hypertension and tachycardia. • Monitor nutritional status, hydration, and weight. Patient teaching • Tell patient taking extended-release capsules to swallow them whole without chewing, breaking, dividing, or dissolving. [medical-dictionary.thefreedictionary.com]

  Hypertension can also occur with venlafaxine XR, especially at higher doses. Prescribers should be cautious when using this medication for patients with preexisting hypertension. [psychopharmacologyinstitute.com]

• Flushing

  Hot flushes may be associated with fatigue, poor concentration, and depression. [womensmentalhealth.org]

  Clayden, JR, Bell, JW, Pollard, P Menopausal flushing: double-blind trial of a non-hormonal medication. Br Med J 1974 ;1: 409 – 12. Google Scholar | Crossref | Medline 9. [journals.sagepub.com]

• Leg Cramp

  Musculoskeletal system— Infrequent: arthritis, arthrosis, bone pain, bone spurs, bursitis, leg cramps, myasthenia, tenosynovitis; Rare: pathological fracture, myopathy, osteoporosis, osteosclerosis, plantar fasciitis, rheumatoid arthritis, tendon rupture [dailymed.nlm.nih.gov]

  cramps, myasthenia, neck rigidity, tenosynovitis Rare (less than 0.1%): Muscle cramp, muscle spasms, musculoskeletal stiffness, myopathy, osteoporosis, osteosclerosis, pathological fracture, plantar fasciitis, rhabdomyolysis, rheumatoid arthritis, tendon [drugs.com]

  Musculoskeletal system—Infrequent: arthritis, arthrosis, bone pain, bone spurs, bursitis, leg cramps, myasthenia, tenosynovitis; Rare: pathological fracture, myopathy, osteoporosis, osteosclerosis, plantar fasciitis, rheumatoid arthritis, tendon rupture [medlibrary.org]

• Mood Swings

  Mood swings are common occurrence. Crying s pells : Crying for no reason is just a sign of severe depression. If you stop using venlafaxine which battles depression, you will experience these crying spells again. [newhealthadvisor.com]

  Any change in mood (deepening depression, mood swings, sudden happiness), unusual thoughts (thoughts of harming self or others, bizarre thoughts, paranoia), anxiety, aggression, irritability, hostility or unusual behavior should be reported immediately [anti-depressants.com]

  Bipolar Disorder Bipolar disorder (or manic depression) is a mental illness characterized by depression, mania, and severe mood swings. Treatment... Panic Attacks Panic attacks are sudden feelings of terror that strike without warning. [medicinenet.com]

  This could involves having suicidal thoughts, severe mood swings, impulsive behavior or incoherent speech. [canadadrugs.com]

• Euphoria

  Nervous system— Frequent: trismus, vertigo; Infrequent: akathisia, apathy, ataxia, circumoral paresthesia, CNS stimulation, emotional lability, euphoria, hallucinations, hostility, hyperesthesia, hyperkinesia, hypotonia, incoordination, libido increased [dailymed.nlm.nih.gov]

  […] and higher blood pressure eye problems, such as blurred eyesight, or your pupils (black centre of the eye) getting bigger nerve problems, such as dizziness, pins and needles, movement problems, or fits mental health problems, such as hyperactivity and euphoria [headmeds.org.uk]

  Common (1% to 10%): Abnormal dreams, abnormal thinking, agitation, anorgasmia, confusion, depersonalization, depression, libido decreased, orgasm disturbance, orgasmic dysfunction Uncommon (0.1% to 1%): Apathy, bruxism, derealization, emotional lability, euphoria [drugs.com]

  Call your doctor straight away if experience : constant headaches, long-lasting confusion or weakness, or frequent muscle cramps can all be signs of low sodium levels in your blood - in severe cases low sodium levels can lead to seizures feelings of euphoria [nhs.uk]

• Hunger

  […] breasts and/or abnormal milk production in women, seizures, fast heart rate, irregular heartbeats, red or purple spots on the skin, low blood sugar and its symptoms (anxiety, chills, cold sweats, confusion, difficulty concentrating, drowsiness, excess hunger [encyclopedia.com]

  I woke up every morning with no appetite whatsoever, and the only way to "enable" my normal hunger was to have something sugary. [mattgemmell.com]

• Sexual Dysfunction

  Dysfunction than Prozac, Zoloft, Paxil Sexual Dysfunction in 10-15% of cases Similar to Luvox and Celexa See Antidepressant Induced Sexual Dysfunction More stimulating (anxiogenic) than sedating Agitation or Insomnia may occur Decreased appetite and [fpnotebook.com]

  Abstract Objective: Many patients with depression suffer from sexual dysfunction and sexual dysfunction is a recognized side‐effect of antidepressants. [doi.org]

  The most common side effect of Effexor is sexual dysfunction in both men and women. Loss of sexual desire also falls into this category. Some of the other most common side effects include brain zaps, nausea, weight gain and fatigue or feeling tired. [web.archive.org]

  Max dose is normally 225mg Nausea, headache, anorexia, nervousness, sweating, somnolence, weight loss, insomnia, dizziness, dry mouth, hypertension, angle closure glaucoma, sexual dysfunction, hyponatremia, and suicidal thoughts or actions. [quizlet.com]

• Seizure

  The seizures were confirmed using amplitude-integrated electroencephalography, and other possible causes of neonatal seizures were excluded. The baby responded to treatment with phenobarbitone and phenytoin. [ncbi.nlm.nih.gov]

  The odds ratio (OR) for seizures with dothiepin vs. other TCAs was 3.4 (95%CI 1.2–9.9). Seizures occurred in 7/51 (14%) venlafaxine overdoses; all patients with seizures consumed ≥900 mg. The OR for seizures vs. TCAs was 4.4 (95%CI 1.4–13.8). [doi.org]

• Myoclonus

  A 29-year-old Taiwanese woman with major depressive disorder abruptly developed serotonin syndrome during low-dose (37.5 mg/d) venlafaxine monotherapy, with symptoms of restlessness, tremor, shivering, diarrhea, vomiting, ataxia, tachycardia, and myoclonus [ncbi.nlm.nih.gov]

  Serotonin syndrome is characterized by rapid development of hyperthermia, hypertension, myoclonus, rigidity, autonomic instability, mental status changes (e.g., delirium or coma), and in rare cases, death. [pdr.net]

  […] derived as a diagnostic criteria that at least 3 of the following symptoms should be present if a serotonergic substance is used and if another etiology or neuroleptic treatment can be ruled out: mental status change (confusion, hypomania), agitation, myoclonus [priory.com]

  John’s Wort, and triptans; symptoms include tremor, myoclonus, diaphoresis, nausea, vomiting, flushing, dizziness, hyperthermia with features resembling neuroleptic malignant syndrome, seizures, rigidity, autonomic instability with possible rapid fluctuations [reference.medscape.com]

• Hyperreflexia

  Soon after administration of the lipid infusion the distinct rigidity and hyperreflexia disappeared. The further course was uneventful. [ncbi.nlm.nih.gov]

  […] diagnostic criteria that at least 3 of the following symptoms should be present if a serotonergic substance is used and if another etiology or neuroleptic treatment can be ruled out: mental status change (confusion, hypomania), agitation, myoclonus, hyperreflexia [priory.com]

  The otherwise highly discriminating neuromuscular features of clonus and hyperreflexia are often not demonstrable in patients with severe rigidity; therefore rule 5 was added despite the fact it was not determined by CART. [doi.org]

• Difficulty Concentrating

  Other symptoms include altered sleep patterns, thoughts of suicide, difficulty concentrating, agitation, lack of energy, and loss of enjoyment in activities that are usually pleasurable. [encyclopedia.com]

  Other symptoms include: Restlessness Fatigue (low energy, feeling tired all the time) Difficulty concentrating Irritability Muscle tension Sleep disturbance (difficulty falling asleep or waking up in the middle of the night) Panic Disorder occurs when [nami.org]

  Signs and symptoms of hyponatremia include headache, difficulty concentrating, memory impairment, confusion, weakness, and unsteadiness, which may lead to falls. [medlibrary.org]

• Tremulousness

  While in the ED, by 5 h after ingestion, the patient had developed tachycardia to a heart rate of 130 beats/min and tremulousness that was treated with a total of lorazepam 2 mg IV. [dx.doi.org]

Patients who responded to 10-week venlafaxine ER 75-300 mg/day treatment and maintained response through a 6-month continuation treatment were assigned randomly to venlafaxine ER or placebo maintenance-phase treatment. [ncbi.nlm.nih.gov]

The treatment may comprise withdrawal of medication and dose reduction, but it is not necessary to use any neuroleptic treatment. References Ebert D, Albert R, May A, et al. [priory.com]

and treatment × severity interaction. [doi.org]

[…] the drug transporter gene ABCB1 predict side effects of treatment with cabergoline in patients with PRL adenomas [ PMID 23093106 ] Detection of frequent ABCB1 polymorphisms by high-resolution melting curve analysis and their effect on breast carcinoma prognosis [snpedia.com]

Long term prognosis in attention deficit hyperactivity disorder. Child Adolesc Psych Clin North Am 2000; 9: 711–26 Google Scholar 19. Biederman J, Faraone SV. [dx.doi.org]

Its possible etiologic factors include panic attack, adverse drug reaction, pharmacodynamic interaction, and congenital absence of CYP2D6 enzyme activity. [ncbi.nlm.nih.gov]

Only etiologic studies were considered. Results. Fifteen studies met inclusion criteria. [doi.org]

Presented at the 23rd Annual Meeting of the Society for Pediatric and Perinatal Epidemiologic Research, Seattle, Washington, June 23–24, 2010, the 43rd Annual Meeting of the Society for Epidemiologic Research, Seattle, Washington, June 21–24, 2010, the [doi.org]

Few epidemiologic studies have investigated the use of venlafaxine (Effexor XR capsules, Product Monograph, Wyeth, Montreal, Canada), an antidepressant used to treat major depression and anxiety disorders in adults, during pregnancy. [ncbi.nlm.nih.gov]

Pathophysiological mechanisms implicated in the development of AEP in our patient seems to be associated with eotaxin and serotonin eosinophilic-specific chemoattracting action. [ncbi.nlm.nih.gov]

Venlafaxine extended-release formulation (venlafaxine XR) is a serotonin and norepinephrine re-uptake inhibitor with antidepressant and anxiolytic properties relevant to the pathophysiology of PTSD. [doi.org]

PURPOSE: Previous pilot data suggested that venlafaxine could prevent acute and chronic oxaliplatin-related neuropathy. [ncbi.nlm.nih.gov]

Silberstein, Preventive Migraine Treatment, Neurologic Clinics, 27, 2, (429), (2009). E. [dx.doi.org]

Researchers concluded that Effexor has potential as a headache prevention drug. [nmihi.com]