Presentation
We present six cases of poisoning due to ingestion of Veratrum viride (false hellebore) and review the physiology of veratrum alkaloids. [ncbi.nlm.nih.gov]
Symptoms typically presented within an hour, after which calls were made to authorities. After sneezing, the victims began to develop gastrointestinal disturbances such as vomiting in all cases and epigastric pain in two. [en.wikipedia.org]
We present a case of accidental poisoning from Veratrum parviflorum mistaken for the edible Allium tricoccum (ramps, wild leek). [tandfonline.com]
Even ingesting a small amount can be lethal due to toxic steroidal alkaloids present, especially in roots, shoots, and rhizomes. [centralcoastbiodiversity.org]
(Wetland indicator code: FACW) New England Distribution and Conservation Status Distribution Connecticut present Maine present Massachusetts present New Hampshire present Rhode Island present Vermont present Conservation Status Exact status definitions [gobotany.newenglandwild.org]
Entire Body System
- Pallor
Veratrum Album Useful for: Key Symptoms: HEAT EXHAUSTION Pallor Nausea Prostration Pulse feeble & rapid Clammy sweat Weakness SUDDEN COLLAPSE Extreme coldness, blueness & weakness Cold sweat, especially on forehead HEADACHE With nausea, vomiting & diarrhea [elixirs.com]
Respiratoric
- Sneezing
[…] poisoning of those who used it. [17] Sneezing powders are commonly used to prank others. [en.wikipedia.org]
Incidents At higher doses, sneezing powder has been found to cause more than just sneezing. A 1983 report from a poison control centre in France examined nine cases of poisoning resulting from sneezing powders containing Veratrum alkaloids. [thepoisongarden.co.uk]
Since the plant induces sneezing, its German name is niewurz, meaning “sneezing root”. The sneezing powder was believed in ancient times to purge the demons of illness from the body. [entheology.com]
UPDATE: I added some “Toxic Tidbits” about Moxie and a 1982 outbreak of sneezing powder intoxications involving Veratrum album. Yes, sneezing powder. [naturespoisons.com]
Elsewhere in cooler parts of Eurasia, where it grows quite commonly and sometimes abundantly, it has been used to make sneezing powder, but it is so rare in Finland that it must not be collected. False helleborine is extremely poisonous plant. [luontoportti.com]
- Dyspnea
SYMPTOMS : Species vary in physiologically active principles, yet symptoms of acute poisoning are constant: salivation, vomiting, diarrhea, stomach pains, prostration, depressed heart action, general paralysis, spasms, and dyspnea. Death may result. [research.vet.upenn.edu]
Difficult (dyspnea) Loud ≡ more ... ▲ COUGH Cough Cough from deep down evening Hollow Comes on suddenly ≡ more ... ▲ SKIN Skin Cold sweat Wrinkling of skin of hands and feet. [abchomeopathy.com]
Gastrointestinal
- Vomiting
Veratrum Album pellets are indicated for Collapse, Coughs, Cramps, Vomiting, Weakness. [naturesfarmacy.com]
Also remember Veratrum Album when diarrhea, vomiting, headache comes simultaneous with subsequent severe weakness. [elixirs.com]
vomiting; forcible vomiting; during vertigo, dizziness vomiting; violent vomiting; black vomiting; frothy vomiting; green vomiting; sour vomiting; water vomiting; yellow ≡ more ... ▲ RECTUM, ANUS, STOOL Rectum Constipation from inactivity of rectum, [abchomeopathy.com]
Other indications for its use include cold sweat - particularly on the forehead, thirst, profuse rice water stools, profuse vomiting, and vomiting and diarrhea that can be virtually simultaneous. [homeopathyworks.com]
Menstrual cramps with coldness, prostration. vomiting and diarrhea. [homeopathyforwomen.org]
- Nausea
Cocculus – Indications for this remedy include nausea or motion sickness, dizziness, palpitations, headache, numbness, and an empty or hollow feeling in various parts of the body. [homeopathyonline.org.uk]
Nausea and vomiting also occur typically after ingestion. Atropine is the mainstay of therapy, but pressors may be required to maintain blood pressure. Cases of veratrum poisoning have not been widely reported in the emergency medicine literature. [ncbi.nlm.nih.gov]
Veratrum Album Useful for: Key Symptoms: HEAT EXHAUSTION Pallor Nausea Prostration Pulse feeble & rapid Clammy sweat Weakness SUDDEN COLLAPSE Extreme coldness, blueness & weakness Cold sweat, especially on forehead HEADACHE With nausea, vomiting & diarrhea [elixirs.com]
Good old nausea, vomiting, and diarrhea round out the gastrointestinal system. Fun times, fun times. [naturespoisons.com]
- Diarrhea
Veratrum album would be given for watery diarrhea, and Podophyllum for diarrhea with few other symptoms. If.Poiyarch root of Veratrum (a monocotyfedon). Veratrum is an alpine genus of the north temperate zone. (3) Quinoline group. [yourdictionary.com]
Also remember Veratrum Album when diarrhea, vomiting, headache comes simultaneous with subsequent severe weakness. [elixirs.com]
Menstrual cramps with coldness, prostration. vomiting and diarrhea. [homeopathyforwomen.org]
Veratrum album is a homeopathic remedy often used for individuals suffering with profuse and often violent diarrhea and vomiting accompanied by a great coldness and weakness. [naturesfarmacy.com]
- Abdominal Pain
Following the ingestion of Veratrum alkaloids, expected signs and symptoms include vomiting and abdominal pain, followed by cardiovascular effects such as bradycardia, hypotension and cardiac conduction abnormalities and death. [ncbi.nlm.nih.gov]
pain, sinus bradycardia, and hypotension. [en.wikipedia.org]
Symptoms typically occur between 30 minutes and 4 hours after ingestion and include nausea and vomiting, abdominal pain, numbness, headache, sweating, muscle weakness, bradycardia, hypotension, cardiac arrhythmia, and seizures. DO NOT EAT! [ballyrobertgardens.com]
Within 15-30 min of ingestion they developed nausea, vomiting, and abdominal pain. At the same time dizziness, tingling, dimmed and jumping vision, transient blindness, and confusion appeared. [pubmed.ncbi.nlm.nih.gov]
- Abdominal Cramps
He develops painful abdominal cramps. The main indications It can be used to treat diarrhoea with abundant stools, dehydration and stomach cramps. [homeopathy-information.com]
Cardiovascular
- Palpitations
Heart: palpitation, pulse irregular, feeble, intermittent, < anxiety, < feeble persons, < hepatic obstruction; tobacco heart from chewing. [qjure.com]
Constriction, tension Heart; palpitations Oppressed feeling Respiration Heart; Palpitation with anxiety and rapid audible respiration Hoarse, weak voice Rattling in chest Much mucus in bronchial tubes, that cannot be coughed up Coarse rales Chronic bronchitis [abchomeopathy.com]
Palpitation with anxiety and rapid audible respiration. Pulse irregular, feeble. Tobacco heart from chewing. Intermittent action of heart in feeble persons with some hepatic obstruction. One of the best heart stimulants in homeopathic doses (J. [homeoint.org]
- Tachycardia
VERATRUM viride, the American false hellebore, has been used intermittently for over a hundred years in the treatment of fever, tachycardia and disturbances of the circulation. [nejm.org]
Face, Head & Neck
- Risus Sardonicus
Risus sardonicus. Mouth.- (Veratrum album) Tongue cold (Camph., Naja) ; dry, blackish (Op., Phos.), cracked ; red and swollen. ( Bell., Rhus tox .) Dryness of the mouth and palate. (Apis, Ars., Nux m.) [homeoint.org]
Neurologic
- Headache
Also remember Veratrum Album when diarrhea, vomiting, headache comes simultaneous with subsequent severe weakness. [elixirs.com]
In addition, hallucinations, headache, and a burning sensation of mouth and throat have been reported. [research.vet.upenn.edu]
Daily dosage varied from 15 to 30 Craw units. 2a The only reactions noted were vomiting in 1 patient and headache in another. No effect of the drug was noted on occasional electrocardiograms. [jamanetwork.com]
INTRODUCTION: Veratrum album (white or false hellebore) is a poisonous plant containing steroidal alkaloids that cause nausea, vomiting, headache, visual disturbances, paresthesia, dizziness, bradycardia, atrioventricular block, hypotension, and syncope [ncbi.nlm.nih.gov]
Rectum.-- Constipation from inactivity of rectum, with heat and headache. Constipation of babies, and when produced by very cold weather. Stools large, with much straining until exhausted, with cold sweat. [homeoint.org]
- Irritability
Veratrum Album contains a very powerful alkaloid, Veratralbine, and also an irritant poisonous resin (?). [henriettes-herb.com]
Sometimes the violent form of mania alternates with a "disposition to silence," but if irritated gets mad, scolds, calls names and talks of the faults of others. [vithoulkas.com]
[…] of mucous membranes. [25] When ingested, the irritation of the mucosal membranes of the stomach and intestines will cause nausea and vomiting. [22] [25] If the herb is introduced to the nose, this mucosal irritation will cause sneezing and coughing. [en.wikipedia.org]
It is especially indicated for a woman who is feeling irritable, sad, worn out, and indifferent to her family. She feels worst in the morning before she eats, but is not improved by eating and may vomit afterward. [homeopathyonline.org.uk]
Medicinal Action and Uses--- A violent, irritant poison. When snuffed up the nose it occasions profuse running of the nose; when swallowed, severe vomiting and profuse diarrhoea. [botanical.com]
- Screaming
; with inconsolable weeping, howling (Cic .), and screaming over some fancied misfortune. Delirium ; talks about religious things (Ars., Aur.) ; praying, cursing, and howling all night ; loquacious. [homeoint.org]
Treatment
[ edit ] Treatment for Veratrum alkaloid poisoning include supportive care and symptomatic treatments, such as fluid replacement and anti-emetics. [en.wikipedia.org]
Some of these opinions may contain information about treatment or uses of drug products that have not been approved by the U.S. Food and Drug Administration. WebMD does not endorse any specific product, service, or treatment. [webmd.com]
The entire treatment took approximately seven hours. [entheology.com]
Etiology
Etiology In Veratrum Album, discharges can be enormously. This loss of fluids leads to collapse and great coldness of the body, followed by cramps or spasms, probably due to the potassium, magnesium and calcium loss. [arscurandi.ca]
Pathophysiology
In China, Veratrum treatment often leads to many side effects and even causes the death of patients, but the pathophysiological mechanisms under these adverse effects are not clear. [mdpi.com]
Prevention
Laboratory not useful Lesions typical fetal malformations Treatment not useful Prevention keeping animals away from Veratrum sp. during the first trimester of pregnancy has largely eliminated the problem in sheep. [research.vet.upenn.edu]
Steroidal alkaloids prevent repolarization (a return to “ready status”) in neurons after a signal is transmitted, which results in multiple depolarizations (firings) of a nerve cell in response to a single stimulus. [mlbs.virginia.edu]
[…] becoming the first foreign vessel to enter San Francisco Bay, and in 1794 Vancouver was able to persuade the Hawaiian King Kamehameha and the other district chiefs to cede the lands under their control to England, something which the Napoleonic Wars prevented [calflora.net]