Presentation
In patients with vernal conjunctivitis, acute hydrops may be the presenting sign of keratoconus in preadolescence. [ncbi.nlm.nih.gov]
[Figure 4] shows the associated ocular disorders presented. Systemic allergic associations were rare. Most of the patients seen did not present with a related medical or family history of systemic allergic associations. [smjonline.org]
The main presenting features of these patients were as follows. · The eye ball is seldom affected · Always presents with itching and burning · Intolerance to light, sunlight. · Conjunctival troubles are often psoric · Constant desire to rub the eyes. [homoeotimes.com]
Mild limbal hypertrophy was present. Treatment included topical 0.1% betamethasone, 0.2% olopatadine (an antihistamine and a mast-cell stabilizer), and tear substitutes. [nejm.org]
We are presenting a case report of a young male patient who presented with complaints of pain, watering, redness, and photophobia. [tjmrjournal.org]
Entire Body System
- Increased Susceptibility to Infections
susceptibility to infection or superinfection. [link.springer.com]
- Cape Verde
Verde Islands: results of a national eye survey. 61 Schemann JF...Guelfi Y 16877280 2006 42 [Identification of adenovirus associated with conjunctivitis by molecular methodology]. 61 Mejia-Lopez H...Velez-Montoya R 16888690 2006 43 A clinicopathological [malacards.org]
Eyes
- Chemosis
Prostaglandin D2 is a secondary mast cell mediator that causes redness, chemosis, mucous discharge, and eosinophil chemotaxis in the eye. It may play an important role in allergic ocular disease. [ncbi.nlm.nih.gov]
[…] infection, keratoconus, and vision loss Atopic keratoconjunctivitis: eyelid tightening, loss of eyelashes, cataracts Giant papillary conjunctivitis : eyelid inflammation and ptosis Clinical features History of allergy, asthma, or eczema Itching (pruritus), chemosis [pathologyoutlines.com]
Watering Mucoid stringy discharge Blurred vision Photophobia Difficulty opening eyes on waking NB: the symptoms are often asymmetrical in the two eyes Signs Stringy white mucous exudate Palpebral, limbal and corneal manifestations: Palpebral hyperaemia and chemosis [college-optometrists.org]
This ocular allergy is characterized by bilateral inflammation of the palpebral conjunctiva, itching, conjunctival hyperemia and chemosis among others signs and symptoms. [omicsonline.org]
Differential Diagnosis of Viral, Allergic and Bacterial Conjunctivitis Viral Allergic Bacterial Laterality Unilateral, then bilateral Bilateral Unilateral, then bilateral Tissue response Follicles Chemosis Petechial hemorrhages Subepithelial Infiltrates [reviewofoptometry.com]
- Blepharitis
A rabbit model of staphylococcal blepharitis. Arch Ophthalmol. 1987; 105 409-412 9 Mondino B J. Inflammatory diseases of the peripheral cornea. Ophthalmology. 1988; 95 463-472 10 Schuster V, Seidenspinner S, Zeitler P. et al. [thieme-connect.com]
Chronic and severe anterior blepharitis: the reduction in the tear film associated with blepharitis can cause chronic irritation and scarring. Drugs: may cause mild-to-severe irritation. [patient.info]
(C) Anterior blepharitis in a child. Note the hyperemia and crusts on the anterior lid margin. [onlinelibrary.wiley.com]
S 15097129 2004 47 [Allergic conditions of the eye]. 61 Thurau S 15347048 2004 48 Animal models of allergic and inflammatory conjunctivitis. 61 Groneberg DA...Wahn U 14616119 2003 49 Contact lenses and associated anterior segment disorders: dry eye, blepharitis [malacards.org]
[…] common cause of blepharitis is Staphylococcus. [reviewofoptometry.com]
- Conjunctival Injection
Signs Recurs in warm weather Conjunctival injection with mucoid secretion Severe Palpebral Conjunctivitis Hard flattened papillae with furrows Large "cobblestone" appearance VI. Complications Corneal Scarring and Conjunctival Scarring VII. [fpnotebook.com]
injection superiorly, OU (see Figure 1). [webeye.ophth.uiowa.edu]
Atopic keratoconjunctivits (AKC) Bilateral conjunctival injection with associated eczematoid belpharitis, watery/mucoid discharge, and boggy edema. [eyewiki.aao.org]
Generally, the common problem with vasoconstrictors is that they may cause dependency with resultant rebound conjunctival injection and inflammation. [emedicine.medscape.com]
- Conjunctival Disease
disease, disease, eye inflammation Subclass of eye disease, disease, conjunctival disease, inflammatory disease Authority control Q167844 National Diet Library Auth ID: 00565682 BNCF Thesaurus ID: 40962 Reasonator PetScan Scholia Statistics Search depicted [commons.wikimedia.org]
Diseases Eye Diseases Keratitis Corneal Diseases Hypersensitivity, Immediate Hypersensitivity Immune System Diseases Tacrolimus Tobramycin (...) [tripdatabase.com]
Signs Conjunctival injection with dilated conjunctival vessels. Conjunctival chemosis (conjunctival oedema). [patient.info]
Evaluation of ocular surface inflammation in the presence of dry eye and allergic conjunctival disease. Ocul Surf 3, S161 – S164. Steven, P. & Gebert, A. ( 2009 ). [cambridge.org]
- Burning Eyes
Symptoms include: Burning eyes. Discomfort in bright light (photophobia). Itching eyes. The area around the cornea where the white of the eye and the cornea meet (limbus) may become rough and swollen. [medlineplus.gov]
Symptoms Symptoms include: Burning eyes. Discomfort in bright light (photophobia). Itching eyes. The area around the cornea where the white of the eye and the cornea meet (limbus) may become rough and swollen. [m.ufhealth.org]
Symptoms Symptoms include: Burning eyes. Discomfort in bright light ( photophobia ). Itching eyes. The area around the cornea where the white of the eye and the cornea meet (limbus) may become rough and swollen. [leehealth.org]
Prof Ariyanto Harsono MD PhD SpA(K) 8 9. Burning eyes Discomfort in bright light (photophobia) Itching eyes The area around the cornea where the white of the eye and the cornea meet (limbus) may become rough and swollen The inside of the eyelids [slideshare.net]
Workup
Seasonal allergic conjunctivitis (SAC) is a self-limiting condition that usually exhibits small tarsal papillae.3 Atopic keratoconjunctivitis has prolonged symptoms and can have sight-threatening consequences.3 Your workup should begin with a thorough [reviewofoptometry.com]
[…] blepharoconjunctivitis; SPK, superficial punctate keratitis; NA, not affected. 2 Methods A systematic review of the literature was performed in PubMed and ScienceDirect databases, using the following key words: Allergic Conjunctivitis or Ocular Allergy [AND] Diagnosis workup [onlinelibrary.wiley.com]
Other Pathologies
- Lymphocytic Infiltrate
infiltrates of three patients with Graves' disease. [ncbi.nlm.nih.gov]
Horner-Trantas spots indicate lymphocytic infiltration of the limbal conjunctiva. [jebmh.com]
A classic sign of VKC is Tranta’s dots which represent lymphocytic infiltration of the limbal conjunctiva. [dovepress.com]
Treatment
The mean level of PGE2 in the patients before treatment was found to be slightly lower than that in the control group, and it dropped even lower during treatment. [ncbi.nlm.nih.gov]
[…] that it be used as a second line treatment and is not recommended before 2 years of age. [doi.org]
Treatment of vernal keratopathy- Punctuate epithelial keratitis require no extra treatment except that instillation of steroids should be increased. Large vernal plaque requires surgical excision. [en.wikipedia.org]
Prognosis
Prognosis Since allergic conjunctivitis generally clears up readily, the prognosis is favorable. Complications are very rare, with corneal ulcers or keratoconus occurring rarely. [slideshare.net]
Prognosis- Disease is usually self-limiting and resolves in 5-10 years but may result in complications like Keartoconus. [medchrome.com]
Outlook (Prognosis) The condition continues over time (is chronic). It gets worse during certain seasons of the year, most often in the spring and summer. Treatment may provide relief. [m.ufhealth.org]
The prognosis for VKC patients is generally good and the disease is generally self-limiting with appropriate treatment. [dovepress.com]
Etiology
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10coded.com]
Hereditary and environmental factors may contribute to the etiology of keratoconus and corneal hydrops. [ncbi.nlm.nih.gov]
The virus etiology of the nonbacterial conjunctivitis of the newborn known as inclusion blennorrhea (Lindner1) was confirmed in a former report ;2 in this paper evidence was presented to indicate that the basophilic cytoplasmic inclusion bodies (Stargardt3 [jamanetwork.com]
Etiology Seasonal allergic conjunctivitis (hay fever conjunctivitis) is caused by airborne mold spores, or pollen of trees, grasses, or weeds. [msdmanuals.com]
We do know that all ocular allergies—seasonal, perennial, atopic, iatrogenic and vernal—share a mixed immunological and inflammatory etiology. [reviewofophthalmology.com]
Epidemiology
Case series of 406 vernal keratoconjunctivitis patients: a demographic and epidemiological study. Acta Ophthalmol Scand 2006;84(3):406–10. Lambiase A, Minchiotti S, Leonardi A, Secchi AG, Rolando M, Calabria G, et al. [jamc.ayubmed.edu.pk]
The purpose of this review is to give an update on its epidemiology, immunopathogenesis and management. [ncbi.nlm.nih.gov]
Epidemiology Occurs annually in spring or early summer Affects adolescents Affects Males more often than females III. Pathophysiology Allergic Conjunctiva response to light or heat IV. [fpnotebook.com]
Case series of 406 vernal keratoconjunctivitis patients: a demographic and epidemiological study. Acta Ophthalmol Scand. 2006; 84:406–410. Trocmé SD, Hallberg CK, Gill KS, Gleich GJ, Tyring SK, Brysk MM. [aao.org]
Pathophysiology
However, its aetiology and pathophysiology remain unclear. The clinical course of this disease is usually benign and self-limiting, but a minority of patients will face very debilitating and sight threatening complications. [ncbi.nlm.nih.gov]
Pathophysiology Allergic Conjunctiva response to light or heat IV. Symptoms Bilateral eye involvement Watery Eye Discharge Photophobia Severe eye itching V. [fpnotebook.com]
Although a large body of information exists on the pathophysiology of ACDs, this has not yet lead to the development of clear recommendations and guidelines for the diagnosis of ACDs or development… Publisher Full Text In vitro safety of ketotifen as [unboundmedicine.com]
Sites Unilateral or bilateral; affects palpebral and bulbar conjunctiva Pathophysiology Ocular surface inflammation (usually mast cell driven) is associated with type 1 hypersensitivity reactions ( eMedicine: Allergic Conjunctivitis [Accessed 24 April [pathologyoutlines.com]
Prevention
Prevention Using air conditioning or moving to a cooler climate may help prevent the problem from getting worse in the future. Images References Barney NP, Cook EB, Stahl JL. Allergic and immunologic diseases of the eye. [m.ufhealth.org]
Prevention Using air conditioning or moving to a cooler climate may help prevent the problem from getting worse in the future. References Barney NP, Cook EB, Stahl JL. Allergic and immunologic diseases of the eye. [pennstatehershey.adam.com]
Treatment may include: Antihistamine or anti-inflammatory drops that are placed into the eye Eye drops that prevent a type of white blood cell called mast cells from releasing histamine (may help prevent future attacks) Mild steroids that are applied [medlineplus.gov]
The goals of treatment are the prevention of complications including ulceration, corneal scarring, keratoconus, and blindness. [flatironallergy.com]