Presentation
The typical presentation is with adult-onset sensorineural hearing loss or non-pulsatile tinnitus. In some patients, this goes unnoticed, and presentation is delayed until the lesion is much larger and presents with symptoms related to mass effect. [radiopaedia.org]
We present a case of a patient with confirmed WM who initially presented with peripheral visual, hearing, vestibular losses. Design/Methods:. [neurology.org]
So, in our case of bilateral VII and VIII cranial nerve involvement presented a diagnostic dilemma and definite etiology could not be ascertained. [indianjotol.org]
Neurosyphilis may present as acute meningitis with cranial nerve dysfunction. We present the clinical and MR imaging findings in a case of neurosyphilis causing facial and vestibulocochlear nerve dysfunction. [ajnr.org]
Clinical Presentation : A 71-year-old woman presented with several month history of progressive neurologic decline and a negative extensive workup performed elsewhere. [omicsonline.org]
Entire Body System
- Asymptomatic
It is treated by surgery or radiation therapy, or, in cases where the condition has remained asymptomatic, it is sometimes left alone and observed via MRI scans for any further growth. [livestrong.com]
As many authors have shown before, cranial nerve compression from vascular loop was also incidentally noted in asymptomatic patients when brain MRI was performed for other reasons [ 5 ]. [jneuro.com]
Most patients are asymptomatic (3). The major forms of clinically symptomatic infection are acute syphilitic meningitis, meningovascular syphilis, and parenchymal neurosyphilis (4). [ajnr.org]
Cranial base tumors can often be asymptomatic (without symptoms) until they compromise neighboring structures, so they are often found at advanced stages. [nyhni.org]
Damage to the motor part of the trigeminal nerve can be difficult to detect and is usually asymptomatic if unilateral but the jaw may deviate towards the affected side on opening. [nature.com]
- Surgical Procedure
As it is the most invasive and risky of the surgical procedures offered for this condition, other options such as the Meniette device, Intratympanic steroid therapy and endolymphatic sac decompression are usually considered. [earassociates.com]
- Short Stature
stature homeobox-containing) 114 single sweep P300 64 SOAE (spontaneous otoacoustic emission) 12, 13 SP (summating potential) 25 SPL(sound pressure level) 29 SR (stapedial reflex) 20 SVN (superior vestibular nerve) 134 「T」 「U」 TEOAE (transient evoked [rnavi.ndl.go.jp]
Gastrointestinal
- Nausea
[…] drugs that can reduce dizziness and nausea, and sedatives to allay the anxiety. [neuroequilibrium.in]
The disorder may cause a person to experience such symptoms as sudden, severe vertigo (spinning/swaying sensation), dizziness, balance difficulties, nausea, vomiting, and concentration difficulties. [my.clevelandclinic.org]
Treatment Acute vestibular neuritis is treated with medicines to suppress nausea and dizziness. [everydayhealth.com]
Symptoms include tinnitus, sensorineural hearing loss, dizziness, or vertigo with or without vomiting and nausea. [deafwebsites.com]
[…] autonomic disorders; nausea, vomiting, sweating - vertigo is ALWAYS worse during head movement!! [quizlet.com]
- Vomiting
The disorder may cause a person to experience such symptoms as sudden, severe vertigo (spinning/swaying sensation), dizziness, balance difficulties, nausea, vomiting, and concentration difficulties. [my.clevelandclinic.org]
He or she may also give you other medicines, such as antiemetics, antihistamines, and sedatives, to help control the nausea and vomiting caused by vertigo. Vertigo usually gets better as your body adjusts ( compensation ). [northshore.org]
Problems with the vestibulocochlear nerve can result in vertigo, vomiting, ringing in the ears, a false sense of motion, motion sickness, or even hearing loss. [healthline.com]
Steroids, antiviral drugs, and antibiotics (if a bacterial infection is present) may also be prescribed, and intravenous fluids may be administered if a person has become dehydrated from vomiting. [everydayhealth.com]
Symptoms include tinnitus, sensorineural hearing loss, dizziness, or vertigo with or without vomiting and nausea. [deafwebsites.com]
Ears
- Tinnitus
Conclusion: Tinnitus due to vascular pressure is a syndrome which should be considered in differential diagnosis in case of tinnitus. Keywords Tinnitus; Vascular loop syndrome; VIIIth Cranial nerve; Anterior inferior cerebellar artery (AICA). [jneuro.com]
For pulsatile tinnitus and typewriter tinnitus, the contact is at the peripheral nervous system segment. The tinnitus is unilateral and characterized by intermittent paroxysms of tinnitus. [link.springer.com]
Objective tinnitus refers to noise audible to both the patient and the examiner, as occurs in carotid stenosis. Most tinnitus is subjective tinnitus. It may vary in pitch and intensity, and may be continuous or intermittent. [neupsykey.com]
Clinical signs are varying degree of HEARING LOSS; VERTIGO; and TINNITUS. [profiles.umassmed.edu]
- Hearing Impairment
Disease, damage, or deformity of the cochlear hair cells is a common cause of hearing impairment or deafness. These malfunctioning hair cells may send intermittent or unclear signals to the auditory nerve, or send no signal at all. [msdmanuals.com]
Danielidis and other scientists from the Department of Otorhinolaryngology at the School of Medicine at Democritus University in Greece and published in the journal "Audiology & Neuro-ontology" states that "hearing impairment is a well-known consequence [livestrong.com]
Evaluation of hearing impairment in leprosy patients taking multidrug therapy. Indian J Lepr, 2013; 85(4); 171-6. Sacheri, R. F(1963). Auricular leprosy and disturbance of hearing. Int.J.Lepr.33:383. Singh SR, et al. [hearinghealthmatters.org]
Lesion of the tensor tympani branch → hearing impairment (particularly difficulty hearing low-pitched sounds) Lesions of the trigeminal nerve nuclei : Depending on which nuclei are affected ;, the patient may present with ipsilateral weakness of muscles [amboss.com]
- Sudden Hearing Loss
The first symptom is usually a gradual loss of hearing in one ear, often accompanied by ringing in the ear (tinnitus) or a feeling of fullness in the ear. Less commonly, acoustic neuromas may cause sudden hearing loss. [webmd.com]
Audiograms revealed severe-to-profound sensorineural hearing loss on the left and severe sensorineural hearing loss on the right. [ajnr.org]
Bilateral sudden sensorineural hearing loss caused by Charcot-Marie-Tooth disease. J Laryngol Otol 2003 May;117(5):399-401 Pelosi, S., et al. (2012). [dizziness-and-balance.com]
Neurologic
- Vertigo
[…] in: - Vestibular neuronitis - Acute posttraumatic vertigo - Benign paroxysmal positional vertigo - Meniere's disease - VN: acute attack - APTV: continous - BPPV: several seconds, no more than 1 min - Meniere's: min--> hours treatment of acute vertigo [quizlet.com]
They may reduce symptoms of vertigo. [northshore.org]
The most common single cause of positional vertigo is so-called "benign paroxysmal positional vertigo" (BPPV). The characteristic complaint is of vertigo, which is severe and relatively brief, after turning in bed. [dartmouth.edu]
vertigo, also known as dizziness, in their lifetime. [southdenverneurosurgery.org]
- Headache
There are often no specific symptoms of meningiomas other than headache. [nyhni.org]
This condition—which involves dizziness, hearing loss, and headache—tends to last a few days or weeks, and then gradually subsides. Acute Vestibular Neuropathy This is damage to the vestibular portion of cranial nerve VIII. [abmp.com]
Kids may seem momentarily scared and unsteady and also may have nausea, vomiting, involuntary eye movements, or headaches. [m.kidshealth.org]
Complications: Pain and headache: These are usually short lived. Hearing loss: The surgery is designed to eliminate balance fibers and maintain hearing fibers, but this is sometimes not possible. Hearing loss may occur, and be mile to profound. [earassociates.com]
She presented to our institution with complete left facial weakness, left-sided deafness, gait unsteadiness, headache and anorexia. [omicsonline.org]
- Cranial Neuropathy
Multiple cranial neuropathies are common, particularly in lesions arising from tumors, trauma, impaired blood flow, and infections. [amboss.com]
Meningeal irritation results in cranial neuropathies because the meningeal disease extends along the nerves at the base of the brain. Cranial nerves seven and eight are most frequently involved in syphilitic basilar meningitis (3). [ajnr.org]
The diseases often associated with bilateral peripheral paralysis are neurosarcoidosis, multiple idiopathic cranial neuropathies, brain stem encephalitis, benign intracranial hypertension, Guillain-Barre syndrome, bacterial meningitis, leukemia, syphilis [indianjotol.org]
Eidelman BH, VK Nielsen, M Møller et al (1985) Vascular compression, hemifacial spasm, and multiple cranial neuropathy. Neurology 35:712–6. PubMed CrossRef Google Scholar 73. Schwaber M (1994) Vascular compression syndromes. [link.springer.com]
The effects of the erosion of surrounding structures include: Headaches Cranial neuropathies (disease or non-function of the twelve large, paired nerves exiting the base of the brain) Frontal lobe symptoms such as alterations in personality. [nyhni.org]
- Seizure
[…] balance-related symptoms can take a real toll on kids — physically and emotionally — and cause other symptoms like: frequent headaches or migraines nausea, vomiting, and diarrhea motion (car) sickness changes in heart rate and blood pressure fatigue seizures [m.kidshealth.org]
She collapsed and had a generalized seizure and was transferred to our institution at the end of July 2013. [omicsonline.org]
The symptoms appear from months to a decade after the primary infection and may include seizures, hemiplegia, insomnia, personality changes, and dementia. [ajnr.org]
If vertigo is the only symptom, it is difficult to diagnose seizure or migraine until or unless more characteristic features arise. [dartmouth.edu]
[…] evoked potentials, provide further diagnostic information in the setting of cranial nerve associated dysfunction in smell, vision, and hearing, as well is in lower neurologically functioning individuals. 8,10 Electroencephalograophy should be employed if seizures [now.aapmr.org]
- Areflexia
CANVAS Syndrome CANVAS is an easy to remember acronym for cerebellar ataxia, neuropathy, and vestibular areflexia. [vestibular.org]
[…] of lesion - hearing is impaired, but tinnitus may occur - mostly in adults between 30-60 years of age - benign condition, lasts some days, can be spontanoues recovery - unknown cause, can be viral - vetibular examination reveals unilateral vestibular areflexia [quizlet.com]
The recently reported "CANVAS" syndrome (cerebellar ataxia, neuropathy, vestibular areflexia) would be a reasonable candidate for this as well. In other words, the vestibular findings of AN may have been largely overlooked. [dizziness-and-balance.com]
Workup
Acute stroke workup, including brain CT/CTA and MRI, were negative except a dolichoectatic basilar artery. [neurology.org]
Extensive systemic workup was likewise unrevealing prior to biopsy of the CPA lesion. [omicsonline.org]
Treatment
Get clear, concise descriptions and evidence-based treatment guidelines for a full range of clinical conditions, ranging from the common to the unusual. [books.google.com]
Treatments might include different; 1) surgical approaches for removal or debulking (partial removal) of a tumor or bone, 2) of radiation treatment or 3) tumor drug treatment. [nf2is.org]
Radiosurgery Radiosurgery treatments can be single or fractionated (multiple smaller treatments rather than one large one). [hopkinsmedicine.org]
If medical treatment does not satisfactorily reduce the symptoms, surgical intervention with a procedure called Microvascular Decompression (MVD) can be performed. [californiaearinstitute.com]
Treatment options There is no cure for auditory neuropathy. [betterhealth.vic.gov.au]
Prognosis
Treatment and prognosis There is variability in the rate of growth of these tumors, and as such, the decision to treat requires consideration of the patient's age and co-morbidities. [radiopaedia.org]
D'Ambrosio AL, Agazzi S (2007) Prognosis in patients presenting with brain metastasis from an undiagnosed primary tumor. Neurosurg focus 22:E7. [omicsonline.org]
Aggressive tumors and those that invade the sphenoid sinus, orbit (eye socket), and dura (outer covering of the brain) are known to have a poorer prognosis. Treatment includes both surgery and radiation with chemotherapy of questionable impact. [nyhni.org]
Cranial Nerve Malignant Neoplasm – Malignant cranial nerve sheath tumors are uncommon and deals with weak prognosis as those of spinal nerves at other places. [knowyourbody.net]
[…] posterior communicating artery aneurysm ) Pupillary sparing → often due to ischemic microangiopathy Treatment Compressive lesions: surgery Ischemic microangiopathy or demyelinating lesions: medical management with adequate control of the underlying disease Prognosis [amboss.com]
Etiology
Etiology Clinical features Extorsion of the eye : inability to depress and adduct the eyeball simultaneously (the pupil shoots upward during attempted adduction of the eyeball) Diplopia ( double vision ) Mild esotropia Trigeminal nerve lesion (V) Etiology [amboss.com]
[…] options Subheadings: analysis anatomy and histology blood blood supply cerebrospinal fluid chemically induced chemistry classification complications congenital cytology diagnosis diagnostic imaging drug therapy economics enzymology epidemiology ethnology etiology [ncbi.nlm.nih.gov]
Olfactory system dysfunction of central etiology is resistant to treatment, and sense of smell is regained by approximately 1/3 of patients within two years. [now.aapmr.org]
Jannetta PJ and DJ Bissonette (1978) Bell’s palsy: a theory as to etiology. Observations in six patients. Laryngoscope 88:849–54. PubMed Google Scholar 46. Schwaber MK and JW Hall (1992) Cochleovestibular nerve compression syndrome. I. [link.springer.com]
BPPV: Etiology and Symptoms The layout of the inner ear is complex. The vestibule, a hollow area at the center of the bony labyrinth, has several sub-portions. [abmp.com]
Epidemiology
PubMed search builder options Subheadings: analysis anatomy and histology blood blood supply cerebrospinal fluid chemically induced chemistry classification complications congenital cytology diagnosis diagnostic imaging drug therapy economics enzymology epidemiology [ncbi.nlm.nih.gov]
The epidemiology and treatment of Bell's palsy in the UK. Eur J Neurol 2002;9:63-7. [ PUBMED ] 4. Keane JR. Bilateral seventh nerve palsy: analysis of 43 cases and review of the literature. Neurology 1994,44:1198-2002. [ PUBMED ] 5. May M, Klein SR. [indianjotol.org]
Epidemiology including risk factors and primary prevention The exact incidence of cranial nerve injuries is unknown. [now.aapmr.org]
Pathophysiology
A disease of the inner ear characterised by episodes of deafness, tinnitus and vertigo, usually preceded by a sense of fullness in the ear; caused by build-up of fluid in the inner ear Describe the pathophysiology of Meniere's disease. 1. [brainscape.com]
Møller AR (1993) Cranial nerve dysfunction syndromes: Pathophysiology of microvascular compression. In: Neuro surgical Topics Book 13, ‘Surgery of Cranial Nerves of the Posterior Fossa,’ Chapter 2. D.L. Barrow, ed. [link.springer.com]
Vestibular nerve histopathology and theory of pathophysiology." Laryngoscope 102(9): 1030-6. [californiaearinstitute.com]
Moller AR (1999) Vascular compression of cranial nerves: II: pathophysiology. Neurol Res 21:439-443. Schwaber MK, Whetsell WO (1992) Cochleovestibular nerve compression syndrome. Ii. Vestibular nerve histopathology and theory of pathophysiology. [jneuro.com]
"Auditory dyssynchrony or auditory neuropathy: understanding the pathophysiology and exploring methods of treatment." Int J Pediatr Otorhinolaryngol 78(2): 171-173. Papadakis CE, Hajiioannou JK, Kyrmizakis DE, Bizakis JG. [dizziness-and-balance.com]
Prevention
[…] cytology diagnosis diagnostic imaging drug therapy economics enzymology epidemiology ethnology etiology genetics history immunology metabolism microbiology mortality nursing organization and administration parasitology pathology physiology physiopathology prevention [ncbi.nlm.nih.gov]
Early detection of changes in hearing can determine the type of loss and may prevent permanent deafness. [deafwebsites.com]
A facial nerve monitor is used to prevent this, and is successful in all but rare cases. Spinal Fluid Leak: Spinal fluid is the fluid that bathes the brain and can leak out into the ear or the wound in any surgery when the dura mater is opened. [earassociates.com]
In most cases a barrier is placed between the two structures (such as Teflon felt) in order to prevent further compression in the future. [californiaearinstitute.com]
Division of STD Prevention, Centers for Disease Control and Prevention, Atlanta, GA. Available at: http://www.cdc.gov/nchstp/dstd/Syphilis_Facts.htm. Accessed October 4, 1999 ↵ STD Surveillance 1998 National Profile: Syphilis. [ajnr.org]