Presentation
These four cases illustrate the wide range of clinical presentations associated with this organism. [ncbi.nlm.nih.gov]
Entire Body System
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Fulminant Sepsis
A healthy man presented with severe abdominal pain, diarrhoea and fever followed by development of multiple blisters, cellulitis and necrotizing fasciitis of the lower limbs, who progressed rapidly to fulminant sepsis caused by this organism. [ncbi.nlm.nih.gov]
Most deaths at that time were occurring due to fulminant sepsis, either in the area of oyster harvest and ingestion, or in tourists returning home. [en.wikipedia.org]
sepsis and are at high risk of mortality. [doi.org]
Recently, a patient with hepatic cirrhosis and hepatic carcinoma suffered fulminant sepsis and necrohemorrhagic bullae secondary to a V. vulnificus infection. The patient had ingested oysters in Mexico City 36 h before [ 54 ]. [intechopen.com]
Respiratoric
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Productive Cough
The fourth case is that of a 32-year-old, human immunodeficiency virus-positive, hepatitis C-positive woman with cirrhosis who presented with productive cough, chills, fever, and red spots on her extremities and buttocks. [ncbi.nlm.nih.gov]
Gastrointestinal
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Abdominal Pain
A healthy man presented with severe abdominal pain, diarrhoea and fever followed by development of multiple blisters, cellulitis and necrotizing fasciitis of the lower limbs, who progressed rapidly to fulminant sepsis caused by this organism. [ncbi.nlm.nih.gov]
Among healthy people, ingestion of V. vulnificus can cause vomiting, diarrhea, and abdominal pain. [aol.com]
Symptoms include vomiting, diarrhea, and abdominal pain. Necrotizing wound infections can occur in injured skin exposed to contaminated marine water. [en.wikipedia.org]
In people with an intact immune system, the infection can cause nausea, abdominal pain, and vomiting. The infection can be much more serious in those whose immune function is compromised. [medicinenet.com]
Musculoskeletal
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Heel Pain
A case of alcoholic liver cirrhosis developed acute left heel pain and swelling 2 days after ingesting raw fish. Two sets of blood cultures indicated V. vulnificus. HLA-B27 was negative. Ultrasonography revealed left Achilles tendinitis. [ncbi.nlm.nih.gov]
Eyes
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Photophobia
The second case was that of a 43-year-old Asian man employed as an oyster shucker who presented with complaints of redness, tearing, and photophobia of the right eye. [ncbi.nlm.nih.gov]
Workup
HLA Type
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HLA-B27
HLA-B27 was negative. Ultrasonography revealed left Achilles tendinitis. Fluid aspirated from the left retrocalcaneal bursa was sterile. The patient recovered completely 3 weeks after treatment. [ncbi.nlm.nih.gov]
Treatment
Furthermore, psammaplin A treatment significantly suppressed the growth of V. vulnificus. Taken together, these results indicate that psammaplin A may be a potential agent for the prevention and treatment of V. vulnificus infections. [ncbi.nlm.nih.gov]
Prognosis
To improve the likelihood of patient survival, an early prognosis of patient outcome is clinically important for emergency/trauma department doctors. [ncbi.nlm.nih.gov]
Once a bloodstream infection occurs, the prognosis is grim: About 50 percent of V. vulnificus bloodstream infections are fatal, according to the Florida Department of Health. [yahoo.com]
The worst prognosis is in those people arriving at hospital in a state of shock. [en.wikipedia.org]
Etiology
Vibrio vulnificus, the etiologic pathogen of the compartment syndrome, was isolated from wound and blood cultures. The patient was treated with systemic antibiotic treatment and multiple forearm fasciotomies. [ncbi.nlm.nih.gov]
[…] of diseases in human communities. 2. the field of medicine concerned with the determination of the specific causes of localized outbreaks of infection, such as hepatitis, of toxic disorders, such as lead poisoning, or any other disease of recognized etiology [vdh.virginia.gov]
Significant SSTIs can also follow marine injuries and exposures in travelers, and the etiologies are often marine bacteria. [doi.org]
Epidemiology
To describe the epidemiology, pathophysiology, diagnosis, treatment, and prevention of Vibrio vulnificus, a rare organism that surfaced following Huricane Katrina and caused serious problems for many victims. [ncbi.nlm.nih.gov]
Bulletin Archive Contact Us Laurie Forlano, DO, MPH, State Epidemiologist Director, Office of Epidemiology 109 Governor Street, 6th Floor East Richmond, VA 23219 Phone: (804) 864-8141 Fax: (804) 864-8139 Contact Us by Email [vdh.virginia.gov]
Study Objective: To describe the clinical and epidemiologic features of Vibrio vulnificus infections. Design: Case series based on notifiable disease report forms and patient medical records. [annals.org]
Pathophysiology
To describe the epidemiology, pathophysiology, diagnosis, treatment, and prevention of Vibrio vulnificus, a rare organism that surfaced following Huricane Katrina and caused serious problems for many victims. [ncbi.nlm.nih.gov]
Pathophysiology V vulnificus infects the body in 2 ways, either by exposure to contaminated seafood, such as raw oysters, or through an open wound exposed to contaminated seawater. [emedicine.medscape.com]
Prevention
Mutation of the vvpM gene appeared to play major role in the prevention of IL-1β production due to V. vulnificus infection in macrophage. [ncbi.nlm.nih.gov]