[…] necrosis and regenerative atypia Microglandular hyperplasia (MGH) of cervix: Has basal squamous metaplasia, prominent subnuclear vacuolization, relatively low proliferation index, lacks stromal foam cells and does not have a conventional EEC pattern present [pathologyoutlines.com]

Most patients present at low stage and have a favorable prognosis.34 This variant of ECa must be distinguished from the following: 1 ECa with osteoid formation. [nature.com]

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  Differential diagnosis Benign Endometrial glandular stromal breakdown: Artifactual crowding due to glandular collapse, predecidual necrosis and regenerative atypia Microglandular hyperplasia (MGH) of cervix: Has basal squamous metaplasia, prominent subnuclear [pathologyoutlines.com]

Endometrial carcinoma: Staging and surgical treatment. UpToDate. Inc. https://www.uptodate.com>. (Consulta: enero de 2021) [ Links ] 20. Fornalik H, Zore T, Fornalik N, Foster T, Katschke A, Wright G. [scielo.org.mx]

Primary treatment is surgical (hysterectomy and bilateral salpingo-oophorectomy with staging), unless patient desires fertility Hormonal therapy (progesterone, leuprolide) alone can lead to complete remission in early stage, low grade tumor for women [pathologyoutlines.com]

CT abdomen / pelvis Enlarged uterus Hypoattenuating, hypoechoic mass in endometrial cavity Used mostly for staging of advanced disease (i.e. lymph node status and distant metastases) Reference: Indian J Radiol Imaging 2015;25:137 Prognostic factors Prognosis [pathologyoutlines.com]

A subtype with favourable prognosis?. Tidsskr Nor Laegeforen. 1996;113:2569-71. Datta CK. Well differentiated papillary villoglandular adenocarcinoma of the uterine cervix. W.V. Med J 1997;93:186-8. [medigraphic.com]

In view of the frequent admixture of VGA and EA and their generally similar biological characteristics, with a prognosis similar to that of typical EA, we conclude that VGA should be considered a variant of EA. [pubmed.ncbi.nlm.nih.gov]

It has a prognosis intermediate between villoglandular carcinoma and serous carcinoma. [nature.com]

[…] estrogen, unopposed by progesterone: Initially, estrogen has mitogenic effect on both endometrial glands and stroma Chronic estrogenic stimulation without progesterone affects glands to a greater extent → glandular overgrowth (hyperplasia) → adenocarcinoma Etiology [pathologyoutlines.com]

Endometrial endometrioid adenocarcinoma refers to a tumor arising from the endometrium, which resembles proliferative type endometrial glands ICD coding ICD-O: 8380/3 - Endometrioid adenocarcinoma, NOS ICD-10: C54.1 - Malignant neoplasm of endometrium Epidemiology [pathologyoutlines.com]

[…] endometriosis Ectopic endometrial glands / stroma are responsive to estrogen stimulation and can also develop an endometrioid-like hyperplasia and subsequently carcinoma (Gynecol Oncol 2002;84:280, Gynecol Oncol 1996;60:238, Int J Gynecol Pathol 1996;15:1) Pathophysiology [pathologyoutlines.com]