A case of severe fluid and electrolyte depletion resulting from a massive villous adenoma of the rectosigmoid colon is presented. The syndrome is discussed, and the often insidious presentation and life-threatening aspects are emphasized. [ncbi.nlm.nih.gov]

Summary A case of severe fluid and electrolyte depletion resulting from a massive villous adenoma of the rectosigmoid colon is presented. The syndrome is discussed, and the often insidious presentation and life-threatening aspects are emphasized. [link.springer.com]

A large morphologically benign lymphoid aggregate is present. No submucosal invasion is identified. [librepathology.org]

Presentation on theme: "Case presentation Transylvania GI Oncology 2014. Case 1 F 63 y Colonoscopy Colonoscopy- 2011 – Stenotic,circuferential neoplasm in the transvers colon. [slideplayer.com]

• Laboratory Technician

  Wallace Jones for advice and criticism in the management of this patient and in the preparation of this manuscript and to the laboratory technicians at Symmes Hospital for co-operation. [nejm.org]

• Diarrhea

  diarrhea, up to 8 times per day. [laendo.net]

  Furthermore, the etiology of the diarrhea is often difficult to establish by the usual technics. [nejm.org]

  When they do occur, however, they may include abnormal bleeding, cramps, abdominal pain, constipation, or diarrhea. [microscopyu.com]

  pain, rectal bleeding, or melena • Lesion closer to rectum: More likely to have diarrhea, electrolyte loss (hypokalemia and hyponatremia) TERMINOLOGY Synonyms Definitions • Adenomatous polyp that contains predominantly villous (“shaggy” surface) elements [radiologykey.com]

  These can also lead to secretory diarrhea with large volume liquid stools with few formed elements. They are commonly described as secreting large amounts of mucus, resulting in hypokalaemia in patients. [en.wikipedia.org]

• Rectal Mass

  Pallor due to occult bleeding Abdominal tenderness Bright red blood on digital rectal examination Rectal mass on digital rectal examination Laboratory Findings Laboratory findings associated with villous adenoma are: Positive fecal occult blood test Hypokalemia [wikidoc.org]

  Rectal bleeding is usually intermittent, with a small amount of dark blood mixed with the stool. A palpable mass in the left side of the abdomen. [surgwiki.com]

Adenomatous Polyposis Peutz-Jeghers Syndrome Other Problems to be Considered: Adenocarcinoma Tubular adenoma Cowden disease Granular cell tumor Hyperplastic polyp Inflammatory polyps Juvenile polyps Lymphoid polyps Mucosal prolapse Solitary rectal ulcer Workup [suprepkit.com]

• Polyps

  Adenomatous tubulo-villous polyp, pedunculated (colon). [pathologyatlas.ro]

  Not all polyps will turn into cancer, and it may take many years for a polyp to become cancerous. [uofmhealth.org]

  A polyp is a lump projecting above the surface of the intestinal lining. The term is no more specific than that and therefore must be preceded by another term identifying the type of polyp, such as adenomatous polyp or hyperplastic polyp. [pezimclinic.com]

  Polyps in the rectum are occasionally palpable by rectal examination, but more often require examination via endoscopy to be discovered. [microscopyu.com]

[…] commonly in rectum or rectosigmoid Less frequent than tubular adenoma ( eMedicine ) May invade directly into colon wall since no stalk is present to serve as buffer zone Higher risk of malignancy than tubular adenoma; 40% risk if sessile and > 4 cm Treatment [pathologyoutlines.com]

Treatment is required only for uncontrollable bleeding or intussusception. Inflammatory polyps and pseudopolyps occur in chronic ulcerative colitis and in Crohn disease of the colon. [merckmanuals.com]

Colonoscopy ( confirmatory test ) References: [1] Treatment Treatment depends on the etiology and nature of the polyp or polyps. References: [1] [2] [amboss.com]

It is currently believed that hyperplastic polyps have no potential to become cancers and hence require no treatment nor follow-up. [pezimclinic.com]

All 4 are effective in catching cancers in the early stages, when treatment is most beneficial. [stlukes-stl.com]

Epidemiology Occurs in one in 10,000–30,000 live births < 1% of colorectal cancers in the U.S. are due to FAP Both sexes equally affected Polyposis typically develops within the third decade of life Clinical features Diagnosis Treatment Prognosis : The [amboss.com]

[15] Prognosis becomes poor with malignant transformation of the lesion. [wikidoc.org]

Villous adenomas have a worse prognosis and warrant closer follow-up. One needs only to remember the criteria for tubular adenomas and villous adenomas, as tubulovillous adenomas are what is left over. [librepathology.org]

Based on the fact that the ascending colon resection showed cancer at regional stage (a positive lymph node), that tumor has a worse prognosis and should be sequence 01. Turn to the colon histology coding rules in your preferred format. [training.seer.cancer.gov]

Colonoscopy ( confirmatory test ) References: [1] Treatment Treatment depends on the etiology and nature of the polyp or polyps. References: [1] [2] [amboss.com]

Furthermore, the etiology of the diarrhea is often difficult to establish by the usual technics. [nejm.org]

(Etiology) Currently, the exact cause and mechanism of formation of Villous Adenoma of Vagina is unknown It is believed to arise from embryological remnants (displaced tissue) during fetal growth and development The kind of tissue that can be abnormally [dovemed.com]

Epidemiology References: [1] [2] [3] Epidemiological data refers to the US, unless otherwise specified. Etiology Classification The majority of colon carcinomas develop from adenomas ( adenoma‑carcinoma sequence). [amboss.com]

Methods for pooled analyses of epidemiologic studies. Epidemiology, 4 : 295 -302, 1993. ↵ Terry M. B., Gammon M. D., Ng-Mak D., Thompson W. D. Re: “p53 protein overexpression in relation to risk factors for breast cancer.” Am. J. [cebp.aacrjournals.org]

[…] colon polyp with at least low grade dysplasia Precursor to invasive adenocarcinoma Essential features Dysplastic nuclei (elongated and hyperchromatic pseudostratification) < 25% villous component ICD coding K63.5 : colon polyp D12.6 : adenomatous polyp Epidemiology [pathologyoutlines.com]

Methods Statistics Trigonometry Medical & Nursing Anatomy Anesthesiology Audiology Bacteriology Biochemistry Bioethics Biomedical Science Cardiology Cardiovascular Childbirth Chiropractic Dentistry Dermatology Diagnostic Imaging Drugs Endocrinology Epidemiology [brainscape.com]

"Epidemiology of colorectal polyps". Tech Coloproctol. 8 Suppl 2: s243–7. doi : 10.1007/s10151-004-0169-y. PMID 15666099. ↑ Jin Y, Yao L, Zhou P, Jin S, Wang X, Tang X; et al. (2018). "[Risk analysis of the canceration of colorectal large polyps]". [wikidoc.org]

[…] undergoing colonoscopy are found to have at least one adenoma ( N Engl J Med 2006;355:2551 ) Men more commonly affected than women ( Gastrointest Endosc 2011;74:135 ) Sites Found more commonly in the left colon and rectum compared with other polyps Pathophysiology [pathologyoutlines.com]

Sleisenger and Fordtran's Gastrointestinal and Liver Disease: Pathophysiology/Diagnosis/Management. 10th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 126. [medlineplus.gov]

Sleisenger and Fordtran's Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, and Management. 6th ed. Philadelphia: WB Saunders; 1997. 467-71. Mandel JS, Bond JH, Church TR, et al. [emedicine.medscape.com]

Sleisinger & Fordtran's Gastrointestinal and liver disease; pathophysiology, diagnosis, management. 6th ed. Philadelphia: Saunders, 1998. 11. Launoy G, Smith TC, Duffy SW, Bouvier V. [aafp.org]

Are Colon Polyps Preventable? There is no definitive, fail-proof method of preventing colon polyps from forming. Avoiding the risk factors one can control, such as tobacco use or poor diet may help to prevent polyps from forming. [sanfranciscocolonoscopy.com]

Prevention of Colon Polyps There is no guaranteed way to prevent polyps from forming. However, the risk of developing polyps can be lowered by taking a few small steps. [gipractice.com]

Printer-friendly Colon Polyps and Cancer Prevention PDF [arizonadigestivehealth.com]

"Aspirin for the Primary Prevention of Cardiovascular Disease and Colorectal Cancer: A Decision Analysis for the U.S. Preventive Services Task Force". Ann. Intern. Med. 164 (12): 777–86. doi : 10.7326/M15-2129. [wikidoc.org]

Nonsteroidal anti-inflammatory drugs, eicosanoids, and colorectal cancer prevention. Gastroenterol Clin North Am. 1996 Dec. 25(4):773-91. [Medline]. Farnell MB, Sakorafas GH, Sarr MG, et al. [emedicine.medscape.com]